PARAMEDIC II MEDICATIONS/DOSAGES Acute Bronchospasm (Asthma, Allergic reactions, COPD ect.) Albuterol (Proventil) 2.5 mg/3 ml and Ipratropium Bromide 0.02% (Atrovent) 0.5 mg/2.5 ml via nebulizer. May repeat Albuterol (Proventil)/Ipratropium Bromide (Atrovent) X 2 if wheezing persists Methylprednisolone (Solumedrol) 125 mg IV if wheezing persists after 1st nebulizer Magnesium Sulfate 2 grams IV in 100 ml NS over 10-15 minutes Epinephrine 1:1,000 0.3 mg IM (severe respiratory distress) Acute Pulmonary Edema Nitroglycerin 0.4 mg spray SL every 5 minutes Albuterol (Proventil) 2.5 mg/3 ml and Ipratropium Bromide 0.02% (Atrovent) 0.5 mg/2.5 ml via nebulizer: Repeat Albuterol (Proventil)/Ipratropium Bromide (Atrovent) X 2 if wheezing persists. Dopamine infusion at 5-20 mcg/kg/min titrated to maintain systolic BP > 90 mm Hg Allergic Reactions Mild Reaction Diphenhydramine (Benadryl) 1 mg/kg IV (Maximum 50 mg) Moderate Reaction Albuterol (Proventil) 2.5 mg/3 ml and Ipratropium Bromide 0.02% (Atrovent) 0.5 mg/2.5 ml via nebulizer: repeat Albuterol (Proventil)/Ipratropium Bromide (Atrovent) X 2 if wheezing persists Diphenhydramine (Benadryl) 1 mg/kg IV (Maximum 50 mg) Allergic Reactions Severe Reaction Epinephrine 1:1,000 0.3 mg IM Albuterol (Proventil) 2.5 mg/3 ml and Ipratropium Bromide 0.02% (Atrovent) 0.5 mg/2.5 ml via nebulizer: repeat Albuterol (Proventil)/Ipratropium Bromide (Atrovent) X 2 if wheezing persists Diphenhydramine (Benadryl) 1 mg/kg IV (Maximum 50 mg) Methylprednisolone (Solumedrol) 125 mg IV Cardiac Arrest due to Allergic Reaction Epinephrine 1:10,000 0.5 mg IV (instead of 1:1,000 IM) For cardiac arrest, refer to the appropriate algorhythm based on presenting rhythm In the setting of cardiac arrest, the following items should be performed in the post resuscitative phase, when time allows: Albuterol (Proventil) 2.5 mg/3 ml and Ipratropium Bromide 0.02% (Atrovent) 0.5 mg/2.5 ml via nebulizer, repeat Albuterol (Proventil)/Ipratropium Bromide (Atrovent) X 2 if wheezing persists Diphenhydramine (Benadryl) 1 mg/kg IV (Maximum 50 mg) Methylprednisolone (Solumedrol) 125 mg IV Altered Mental Status If hypoglycemic (Blood glucose < 70 mg/dL [<50mg/dL if stroke]): Dextrose 50% 25 gm slow IV Thiamine 100 mg IV (malnourished/Alcoholism) If no IV available: Glucose paste or other oral glucose containing agent (e.g. orange juice) if patient alert enough to self administer oral agent Glucagon 1 mg IM If Opioid overdose suspected (significantly altered mental status or respiratory depression): Naloxone (Narcan) 2 mg IV (start at 0.4 mg for patients over 65 years old) Naloxone (Narcan) can be given in 0.4 mg increments, titrated to mental status and respiratory drive (monitor respiratory status with continuous capnography) If respiratory depression persists, repeat every 3 minutes to a maximum of 8 mg Arrhythmias Adenosine Phosphate (Adenocard) 6 mg rapid IV over 1-3 seconds (Tachycardia) If no response in 2 minutes, 12 mg rapid IV over 1-3 seconds If no response in 2 minutes, repeat 12 mg IV over 1-3 seconds Amiodarone 150 mg followed by 150 mg during 2nd round of medications (Ventricular arrhythmias) Behavioral Emergencies Severe agitation compromising patient care or patient/crew safety, or for patients who continue to struggle against physical restraints Haloperidol (Haldol) 5mg IM if < 60 kg and 10mg IM if > 60 kg Avoid if history of recent MAO inhibitor use (e.g. Phenelzine, Tranylcypromine) Lorazepam (Ativan) 1 mg IM (can be combined in same syringe as Haloperidol) If cocaine/sympathomimetic toxicity strongly suspected: Lorazepam (Ativan) 1 mg IV/IM Repeat Lorazepam (Ativan) 1 mg IV/IM if adequate sedation not achieved initially Bites and Envenomations For hypotension (systolic BP < 90 mmHg) not improved by fluid boluses, or when fluid boluses are contraindicated Dopamine infusion at 5-20 mcg/kg/min titrated to maintain systolic BP > 90 mm Hg For Black Widow spider or Scorpion envenomations with severe muscle spasms Lorazepam (Ativan) 1 mg slow IV or IM For patients with severe pain if systolic blood pressure > 120 mmHg: Morphine Sulfate 2 mg slow IV; repeat every 2 minutes as needed (Maximum 10mg) Cardiac Arrest Medications Epinephrine 1 mg every 3-5 mins (all forms of arrest) Amiodarone 300 mg followed by 150 mg during 2nd round of medications (Ventricular arrhythmias) Magnesium Sulfate 2 grams (Torsades) Sodium Bicarbonate 1 mEq/Kg (hyperkalemia, renal disease) Calcium Chloride 1 gram Dopamine infusion at 5-20 mcg/kg/min titrated to maintain systolic BP > 90 mm Hg (post arrest) Chest Pain Aspirin 324 mg PO, chewed if patient is able to swallow Aspirin is contraindicated if allergic or taking Warfarin (Coumadin) Nitroglycerin 0.4 mg spray SL, every 5 minutes as needed for chest pain Contraindicated if systolic BP < 90 mm Hg Contraindicated if use of a Phosphodiesterase-5 (PDE5) inhibitor within last 24 hours (Viagra or Levitra); 48 hours for Cialis Morphine Sulfate 2 mg slow IV; repeat every 5 minutes as needed (Maximum 10 mg) if no chest pain relief after 3rd Nitroglycerin dose If runs of Ventricular Tachycardia occur: Amiodarone 150 mg IV Piggyback over 10 minutes Isolated PVC’s do not require treatment For patients with severe nausea or vomiting: Ondansetron (Zofran), 4 mg slow IV Cyanide poisoning Hydroxocobalamin (Cyanokit) 5 grams (two 2.5 grams vials) IV/IO over 15 minutes Dehydration Normal Saline 250 ml followed by a second infusion of 250 ml if necessary. Drug overdoses Glucagon 3 mg IV/IO for calcium channel and B blocker OD Calcium Chloride 1 gram IV/IO for calcium channel blocker OD Sodium Bicarbonate 1 mEq/kg IV/IO for Tricyclic antidepressant OD Naloxone (Narcan) 2 mg IV repeat every 3-5 minutes (Maximum 8 mg) Hypoglycemia (Blood glucose < 70 mg/dL [<50mg/dL if stroke]) Dextrose 50% 25 gm slow IV Thiamine 100 mg IV (If the patient appears malnourished/alcoholic) If no IV available: Glucose paste or other oral glucose containing agent (e.g. orange juice) if patient alert enough to self administer oral agent If unable to take oral glucose administer Glucagon 1 mg IM Nausea and Vomiting Ondansetron (Zofran), 4 mg slow IV Pain Control (Chest pain, fractures, kidney stones ect.) Morphine Sulfate 2 mg every 2 minutes maximum dose 10 mg unless medical control increases maximum dose. Seizures For active seizures administer Lorazepam (Ativan) 1 mg, slow IV; can be given IM if no IV Available, If seizures continue or re-occur repeat Lorazepam (Ativan) 1 mg IV or IM; wait at least 5 minutes from initial dose.