JORDAN UNIVERSITY OF SCEINCE & TECHNOLOGY
DEPARTMENT OF APPLIED CHEMISTRY
"Spectroscopic Identification of Organic Compounds" Chem. (416)
Read and retain this syllabus. It contains information essential to your success in
this course.
Attendance: Your attendance at all lectures is expected and essential to
your success in this course.
As a rule the student can't miss more than 10% of the lectures with
reasonable excuses from the instructor, and another 10% with reasonable
excuses accepted by the dean of science. If the student misses overall
20% of the lectures, then he or she can't enter the final exam and will fail
the course with 35.
Examination Policy: During this course, there will be a first worth 25.0
points and a second worth 25.0 points, homework and quizzes worth 10.0
points and a final examination worth 40.0 points.
There is NO curve in this course:
Problems: Doing the problems is absolutely essential to your success in
this course. You will not succeed without doing the problems in a timely
fashion. Do not fall behind.
Course Outline
Text Book: 1. Introduction to Spectroscopy by Pavia, Lampman and Kriz.
2. Spectroscopic identification of Organic Compounds by Silverstein,
Bassler, Morrill.
General objectives:
1. In Spectroscopic Identification of Organic Compounds we will explore
the important spectroscopic and analytical techniques used for
structure elucidation.
2. By the end of semester, the students should be able to identify the
structure of organic compounds by analyzing the data that will be
given during the semester such as solubility tests, chemical tests for
functional groups, elemental analysis, molecular formula
determination,
mass
spectrometry,
infrared
spectroscopy,
ultraviolet/visible spectroscopy, nuclear magnetic resonance
spectroscopy.
Chapter that will be covered
1. Organic Qualitative Analysis
Classification of organic Compounds by Solubility Background,
Determination of Solubility, General Solubility Rules, Solubility in
Organic Solvents, Chemical Tests for Functional Groups.
2. Determination of Chemical Formulas
Elemental Analysis, Empirical Formula Determination, Molecular
Mass Determination, Index of Hydrogen Deficiency, Molecular
Formula Determination.
3. Mass Spectrometry
Theory, Instrumentation, Background Information, the Molecular Ion
peak, the Nitrogen Rule, Isotope Ratio Data, Fragmentation Patterns
for Organic Functional Groups (Alkanes, Alkenes, Alkynes, Aromatic
Compounds, Alcohols, Ethers, Aldehydes, Ketones, Esters,
Carboxylic Acids, Amines, Amides, Nitriles, Nitro Compounds,
Halogenated Compounds.
First Exam
4. Infrared Spectroscopy
Background Information, Electromagnetic Radiation, Infrared
Spectroscopy Basics, Instrumentation, General Approach to IR
Spectrum Analysis, and Example Spectra for Various Functional
Groups (alkane, alkene alkyne, alkyl halide, aromatic, alcohol, ether,
aldehyde, ketone, carboxylic acid, ester, acid chloride, acid anhydride,
amine, and amide.
5. Ultraviolet/Visible Spectroscopy
Background Information, Basic of Ultraviolet Light Absorption,
Terminology, Laws of Light Absorption, Measurement of the
Spectrum, Solvents for UV/Vis Spectroscopy, UV/Vis Spectroscopy
Generalization, Types of Electronic Transitions, Empirical Rules for
Calculating Uv/Vis Absorptions.
Second Exam
6. Nuclear Magnetic Resonance Spectroscopy
NMR Basics and 1H Resonance, Nuclear Spin States, Chemical Shift,
Instrumentation, Solvents for 1H NMR, Chemical Equivalence,
Integration, Factors Influencing Chemical Shift, 1H Correlation Chart,
Spin-Spin Splitting (n + 1 Rule).
13
C Resonance, Background, 13C Correlation Chart, 13C Correlation
Chart for Carbonyl Compounds, Solvents for 13C NMR, ProtonCoupled 13C Spectra, Proton-Decoupled 13C Spectra, Off-Resonance
Proton-Decoupled 13C Spectra, Nuclear Overhauser Enhancement,
Problems with Integration of 13C Spectra, Heteronuclear Coupling in
13
C Spectra Calculating Chemical Shift Values: In 1H NMR
Spectroscopy: Disubstituted Methylenes, Substituted Alkenes,
Substituted Benzene Rings. In 13C NMR Spectroscopy: Inear and
Branched Alkanes, Linear and Branched Alkenes, Substituted
Benzene Rings. Spin-Spin Coupling, Basics of Coupling Constants,
Coupling Patterns in NMR. Advanced NMR Techniques:
Double Resonance, DEPT (Distortionless Enhancement by
polarization Transfer) Experiment, Two-Dimensional NMR
Techniques: COSY (Correlation Spectroscopy) Experiment, HETCOR
(Hereronuclear Correlation Spectroscopy) Experiment.
Final Exam
Grading
First Exam
Second Exam
Quizzes
Final
25%
25%
10%
40%