Template For Basic Sciences Permission to Write (Nutrition and Pharmacy) PERMISSION TO WRITE MEETING Title of Research Proposal Student Name (Supervisor) Date Table of Contents Table of Contents .................................................................................................................. ii List of Figures ........................................................................................................................iii List of Tables ........................................................................................................................ iv List of Abbreviations .............................................................................................................. v Introduction ............................................................................................................................ # Literature Review ................................................................................................................... # Heading 1 ........................................................................................................................ # Subheading 1 .............................................................................................................. # Heading 2 ........................................................................................................................ # Subheading 2 .............................................................................................................. # Hypothesis ............................................................................................................................. # Objectives .............................................................................................................................. # Materials and Methods........................................................................................................... # Materials .......................................................................................................................... # Experiment 1 ................................................................................................................... # Assay 1............................................................................................................................ # Statistical Analysis ........................................................................................................... # Results ................................................................................................................................... # Experiment 1 ................................................................................................................... # Experiment 2 ................................................................................................................... # References ............................................................................................................................ # ii List of Figures Figure 1. Title 1 ...................................................................................................................... # Figure 2. Title 2 ...................................................................................................................... # Figure 3. Title 3 ...................................................................................................................... # Figure 4. Title 4 ...................................................................................................................... # iii List of Tables Table 1. Title 1 ....................................................................................................................... # Table 2. Title 2 ....................................................................................................................... # Table 3. Title 3 ....................................................................................................................... # Table 4. Title 4 ....................................................................................................................... # iv List of Abbreviations ANOVA Barx1 Bmp BrdU DMEM DNA Analysis of variance BarH-like homeobox 1 Bone morphogenic protein 5' Bromodeoxyuridine Dublecco’s modified eagle medium Deoxyribonucleic acid v Introduction Provide a concise overview (2-3 pages) of the major premise of your research (i.e. what you intend to discover and why this is important). Literature Review The literature review needs to be fairly complete. The student should include all the relevant literature in the research area. The literature review is not meant to be exhaustive. The student must distill the important information from the literature and clearly interconnect this information to build the “story” or “argument” for the student’s research. Use headings and subheadings as necessary. Avoid using one continuous text. Length is at the discretion of the supervisor and student. Heading 1 Subheading 1 Heading 2 Subheading 2 Hypothesis You may have more than one hypothesis statement or one global hypothesis statement. The statement(s) should be worded in a manner that results in a testable statement. Objectives The objective statements should clearly identify what you need to do to test your 1 hypothesis statement. After stating a specific objective you have the option to add additional statements to indicate how you will meet the objective (i.e. these could be specific aims that fall under an objective). 1. To determine … 2. To establish … 3. To identify … Materials and Methods Identify the methods and protocols that have been used in accomplishing the goals identified in the objectives. Be very detailed (i.e. provide sufficient detail to allow duplication of your experiments). Always include a statement indicating that your animal use for the proposed research has been approved by the UCACS Animal REB (same applies to human ethics). Materials Experiment 1 Assay 1 Statistical Analysis Always include this section even if you will only use descriptive statistics (i.e. mean ± SD). Results Include all results. Permission to write is granted only when the committee is satisfied that the student has completed a sufficient amount of research and has answered the 2 major research questions well enough to defend the research. Use appropriate and well-formatted tables and figures (format tables and figures according to Graduate Studies guidelines). Table and Figure titles and legends should have sufficient information to completely describe the experiment and the results expressed in the table or figure. Each table and figure should be able to stand alone without the need to refer to the text of the results section. Insert tables and figures when they appear in the text of the results section. Do not place at the end of the document. Do not leave large gaps in the text of the results section. Use appropriate statistics and indicate significance with the actual P value. The type of statistical analysis should appear in the legend of the tables and figures. Be quantitative, indicating the magnitude of the effect as well as the statistical significance. Experiment 1 Experiment 2 Timeline Identify a timeline for completion of the discussion section if Permission-to-Write is granted. References You have a choice of either using numbers within the text with the number corresponding to the order of appearance of the reference or using text Author/Year citation in the text with the reference list in alphabetical order. 3