ANNOUNCING A NEW COURSE SEQUENCE Starting Spring 2009 STAT 4510/7510: Applied Statistical Models I STAT 8220: Applied Statistical Models II A fresh update our classic Regression and ANOVA courses Stat 4510/7510, formerly called Regression and Correlation Analysis, has been updated and re-titled Applied Statistical Models I. The content of this course has been revised to provide a unified presentation of linear models including classical regression and analysis of variance topics. By presenting classical regression and ANOVA topics in a cohesive, condensed format, students will also be exposed to random and mixed effects models in the first semester. Topics in the “new” 4510/7510 include simple linear regression, multiple regression, analysis of designed experiments, multi-factor ANOVA, random effects models, and mixed effects models. Starting in FS2009 the second course in the new sequence, Stat 8220: Applied Statistical Models II, will be offered. This course will focus on important modern modeling techniques with an emphasis on methods and procedures that are of interest to applied researchers. Topics include linear mixed models, generalized linear models, and nonlinear models. Optional topics, time permitting, are generalized linear mixed models, Bayesian estimation, longitudinal data models, nonparametric regression, generalized additive models and log-linear models. During both semesters, students will be expected to apply the techniques learned in class to datasets using statistical software. We anticipate the use of SAS during the first semester SAS and/or R during the second semester. At the present time, we plan to continue offering Stat 4530/7530: Analysis of Variance. Depending on student need, we will re-evaluate the necessity of continuing this course in the future. Other statistics courses that students may find important in meeting their career goals may be found in our Schedule of Planned Statistics Offerings, which is a useful tool for curriculum planning. 1 Stat 4510/7510: Applied Statistical Models I To be offered each fall, spring, and summer starting in Spring 2009 Catalog description: Introduction to applied linear models including regression (simple and multiple, subset selection, estimation and testing) and analysis of variance (fixed and random effects, multifactor models, contrasts, multiple testing). No credit for a graduate degree in statistics. Prerequisite: STAT 3500 or 7070 or 4710/7710 or 4760/7760 or instructor’s consent. Additional requirements for graduate credit: Graduate students will be required to analyze a data set of their own choosing and, time permitting, to make a presentation on their analysis to class. Possible textbook: Applied Regression Analysis and Other Multivariable Methods, 4th Edition, by Kleinbaum, Kupper, Nizam and Muller. Course Topics: Review (1 week) Descriptive statistics; one sample inference for mean and variance, Type I and II errors, sample size and power; two-sample comparison of means and variances. Simple linear regression (3 weeks) Basic regression model and assumptions, least squares estimation; normal error and inference on regression coefficient, intercept, mean response, prediction; ANOVA table, residuals and regression diagnostics, measurement errors. Multiple Regression (4 weeks) ANOVA table, inference on regression coefficient, mean and prediction, partial determination, Type I and II sums square, polynomial regression, categorical variables, interaction term, diagnostic (outliers of X, Y, influential observation, multicolinearity), remedial measures (weighted least squares, variance stabilizing transformations), model selection and validation. Analysis of Designed Experiments / One Way ANOVA (1 week) Completely randomized designs, one-factor fixed effects model, alternative formulations and restrictions on parameters, contrasts, multiple comparisons; estimation and inference, F- and t-tests. Multi-Factor ANOVA (3 weeks) Two-factor fixed effects models (balanced and unbalanced designs, alternative models formulations and restrictions, interaction, orthogonal contrasts, nonorthogonal decompositions, Type III sums of squares, F-tests. Introduction to Random Effects (1 week) One-factor random effects models, estimation, F-tests; two-factor random/mixed effects models (balanced designs, variance components, estimation and inference). Analysis of Covariance (1 week) Software: SAS 2 STAT 8220: Applied Statistical Models II To be offered each fall, spring, and summer starting in Fall 2009 Course description: Advanced applied linear models including mixed linear mixed models (fixed and random effects, variance components, correlated errors, split-plot designs, repeated measures, heterogeneous variance), generalized linear models (logistic and Poisson regression), nonlinear regression. No credit for a graduate degree in statistics. Prerequisites: STAT 4510/7510 or instructor’s consent. Possible Textbooks: Applied Regression Analysis and Other Multivariable Methods, 4th Edition, by Kleinbaum, Kupper, Nizam and Muller. Linear Mixed Models by West, Welch and Galecki Course Topics: Review of Fixed and Random Effects models Linear Mixed models Hierarchical framework, correlated error structure, split-plot designs, repeated measure designs, heterogeneous variance. Generalized Linear Models Logistic regression (binomial response), Poisson regression, model structure (link functions), missing values, inference, overdispersion Nonlinear Regression Methods Nonlinear least squares, numerical methods, practical issues, statistical properties, examples. Additional topics (time permitting): Generalized linear mixed models, Bayesian estimation, longitudinal data, nonparametric regression, generalized additive models, log-linear models Software: R, SAS, etc. 3