Partners Research Studies Seeking Volunteers
1. Do You Have Insomnia?
Brigham and Women's Hospital is conducting a research study testing the effects of a sleep medication and metabolism (how the body processes sugar). We are currently enrolling people between the ages of 25-55 who have insomnia.
The study involves 9 visits, including 3 overnight stays.
Compensation is dependent on the number of completed visits & ranges from $25 up to $1,800.
To find out more contact: Shawn insomniastudy@rics.bwh.harvard.edu
(617) 525-6490 IRB# 2005-P-001997
2. Do You Have Asthma?
The Asthma Research Center at Brigham and Women’s Hospital is recruiting asthmatics aged 18-50 who use asthma medication to control their symptoms. The research study involves 12 visits over a 6-month period and involves bronchoscopies. The study’s purpose is to assess the safety and effectiveness of a new medication in the treatment of asthma. Compensation up to $1650 will be provided at the end of participation. Call us at
617-732-8259 or 1-888-99ASTHMA for more information. IRB#2007-P-001797
3. Brigham and Women’s Hospital in Boston seeks 20 to 75 year old males and females with high blood pressure (ranging from 135/85 to 160/100) and obstructive sleep apnea to participate in a research study investigating a new treatment for high blood pressure. The study involves using a breathing device every day at home for 8 weeks. You may continue to take your blood pressure medicines during the study. You will have your blood pressure measured for 24 hours every 4 weeks. You may will receive up to $550.00 payment for participation. For more information on the “Hy-PAP study” please call Ashley toll-free at 1-877-I-SNORE2 ext. 2 or e-mail at hypap@partners.org
IRB #: 2006-P-002252
4. Are you depressed? Have you stopped getting your period?
For more information contact Janet Lydecker at (617) 724-1838 or jlydecker@partners.org.
Women who are currently depressed and have not had their period for at least three months are needed for a research study at Massachusetts General Hospital. Participants cannot be on oral contraceptive (birth control) pills, and must be 18-45. The study looks at the role of cortisol and other hormones on bone health. Study participants will come to
Massachusetts General Hospital for three visits: two outpatient visits, and one overnight stay. Research participants receive a physical examination, nutritional and body composition analyses, hormonal evaluation, and bone density information at no cost.
Participants also receive reimbursement of local travel/ parking costs, as well as up to
$150 for their participation. IRB# 2003-p-000549
Posted 4/30/08

5. Do you have a Wart?
You may qualify for a research study on an Investigational device.

Age 18-55 years of age

Up to 8 study visits

Remuneration of $40 per study visit
Please call (617) 726-5066 or e-mail us at: harvardskinstudies@partners.org
IRB # 2006-P-001911
6. General Anesthesia Study
The Mass General Hospital Department of Anesthesia and Critical Care is recruiting healthy, non-smoking adults, ages 18-36 years for a research study to identify the sites of action of Propofol anesthesia in the brain. We will be using magnetic resonance imaging
(MRI) and electroencephalogram (EEG) to observe brain activity. Studies will be conducted at the MGH General Clinical Research Center in the Charlestown Navy Yard, and will consist of a physical exam and a 7-hour imaging/EEG/anesthesia session. Two or three visits will be required to complete the study. Subjects will receive up to $200 for completion of the study. For more information, please contact Dr. Emery N. Brown in the
MGH Department of Anesthesia and Critical Care at 617-724-9857 or at mgh.anesthesia.study@gmail.com.http://neurostat.mgh.harvard.edu/anesthesia_eeg.htm
.
IRB #: 2005-P-001549
7. Are you a woman currently taking anti-depressants without relief of symptoms?
You may be eligible for a research study at Massachusetts General Hospital. The study includes:
Medication that may improve depression and energy
Blood tests to measure hormone levels
4 visits to MGH over the course of 8 weeks
3 months of psychiatric care at no cost following participation of study
For more information contact Lindsay Gunnell at (617) 724-1579 or email lgunnell@partners.org
IRB# 2007p000348
8. Got Fibroids?
Volunteers Wanted: SISTERS WHO HAVE (OR HAVE HAD) FIBROIDS
The Center for Uterine Fibroids at Brigham and Women's Hospital seeks participants for a study to identify the causes of uterine fibroid tumors. We are looking for families in which two sisters have (or have had) uterine fibroids. The study involves filling out two surveys and giving a blood sample, all of which can be done by mail at no cost to you.
Please join us in our efforts to search for the causes of uterine fibroids and help future generations of women.
For more information, call the Center at (617) 525-4434, email us at fibroids@rics.bwh.harvard.edu, or visit our web site: www.fibroids.net
<http://www.fibroids.net> . You may also write to us at Center for Uterine Fibroids, 77
Avenue Louis Pasteur, NRB 160, Boston, MA 02115. IRB#: 1999-P-002376/32
Posted 4/30/08

9. Brigham and Women’s Hospital is seeking volunteers for an innovative and unique research project.
OMNI-Carb is a research study of how blood pressure, cholesterol and glucose are affected by what we eat. Blood pressure monitoring, all meals for 21 weeks (1 meal daily in our clinic, M-F), and a stipend of $1500-$1900 are provided.
To join you must be

30 years or older

Have a BMI (Body Mass Index) of 25 or higher

Interested in changing your eating pattern for 21 weeks
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Willing to come to our clinic M-F for one meal
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Have normal or mildly elevated blood pressure
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Are not on blood pressure or cholesterol medications

Are not diabetic
For more information, please call the OMNI Carb study office at 617-525-6737 or visit the web at http://www.OMNICarb.org
IRB# 2007-P-001351
10. Cognitive-Behavior Therapy for Depression in Bipolar Disorder
The MGH Bipolar Clinic and Research Program is currently seeking volunteers to participate in a research study evaluating a psychosocial therapy for the treatment of depressive symptoms in patients with bipolar disorder. In this study, patients will receive
18 sessions of therapy for bipolar depression and a brain scan at no cost.
Bipolar patients above the age of 18, who are currently in a depressive episode, please contact Hannah Lund at hlund@partners.org or call (617) 724-6545 for more information. IRB # 2006-P-001521
11. Researchers from Brigham and Women’s hospital are seeking men and women who are suffering from tunnel vision. If you are between the age of 21 and 65 and cannot see as wide or complete a field of vision as normal, you may qualify for a research study. Eligible candidates will be asked to come to Birgham and Women’s Hospital for a single visit, which consists of answering brief questionnaires, and being given a functional magnetic resonance imaging (fMRI) scan of the brain.
For more information please contact Zvi at 617-732-5969 or zshapiro@partners.org.
IRB# 2007-P-000109
12. Weight Loss Study
The MGH Weight Center is seeking eligible participants to take part in a clinical trial for an experimental weight loss medication. Study related exams and drug as well as individual nutritional counseling will be provided free of charge for those who qualify.
You may be eligible to participate in this investigational research study if you:
Are between 18 and 65 years old
Are not diabetic
Are overweight
Posted 4/30/08

Are not pregnant of planning to become pregnant in the next year
For more information visit http://www.weightcenter.org/ or call 617-724-9616 IRB#
2008-p-000193
13. Healthy Women Ages 21 and older
Researchers at Massachusetts General Hospital and the Foundation for Informed Medical
Decision Making are conducting a study to understand the quality of treatment decisions.
We are seeking healthy women to fill out a questionnaire about breast cancer treatment.
If you are 21 or older and have never been diagnosed with breast cancer, you may be eligible to participate in the study. The survey takes approximately 20 minutes to complete.
All inquiries and returned surveys are kept confidential and identified by code numbers only. Participants will be reimbursed $20 cash or equivalent.
For more information, please email bcaprogram@fimdm.org
or call the program assistant at (617) 724-1506.
IRB#2007-P-002219
14. Healthy Volunteers Wanted for a research study on Vitamin D Deficiency and
Immune Defense
Vitamin D deficiency is a common problem in the Boston area. Most people with
Vitamin D deficiency do not know they have it.
We are looking for healthy volunteers, ages 18-80, to participate in a research study of vitamin D and the immune system. We will check blood levels of vitamin D levels and a protein involved in immune defense.
Participants found to be vitamin D deficient will be offered vitamin D supplements and return in two weeks for repeat levels.
There will be no cost to anyone who participates. No investigational drugs will be used.
All individuals welcome. Women and minorities are encouraged to participate.
For more information, contact Dorrie Sullivan, RN at dsullivan18@partners.org
or 617-
726-5382. IRB# 2008p-000300
15. Are you healthy and between 30 and 60 years old?
We seek men and women to participate as healthy controls (comparison group) for a diabetes research study. You must have never had diabetes. This study involves a single visit to the Mass General hospital during which you will have a glucose tolerance test to screen for diabetes. Recent normal results of this test can be used instead. You will also have two small punch skin biopsies removed from your lower leg under local anesthesia.
Payment for participation is offered. For more information, please contact Max Klein of the MGH Neurology Department at 617-726-9391 (mklein@partners.org).
IRB#99-9042
Posted 4/30/08

16. Weight Loss Study for patients with type-II diabetes
The MGH Weight Center is seeking eligible participants to take part in a clinical trial for an experimental weight loss medication. We are looking for people who are overweight or obese and have type-II diabetes. Study related exams and drug as well as individual nutritional counseling will be provided free of charge for those who qualify.
You may be eligible to participate in this investigational research study if you:
Are between 18 and 65 years old
Have type-II (adult onset) diabetes treated with oral medications only (no insulin)
Are overweight
Are not pregnant or planning to become pregnant in the next year
For more information visit http://www.weightcenter.org/ or call 617-724-9616 IRB#
2007-p-002197
Posted 4/30/08