Partners Research Studies Seeking Volunteers
1. Do you have a Wart?
You may qualify for a research study on an Investigational device.
 Age 18-55 years of age
 Up to 8 study visits
 Remuneration of $40 per study visit
Please call (617) 726-5066 or e-mail us at: harvardskinstudies@partners.org
IRB # 2006-P-001911
2. Do you want to quit smoking once and for all?
Have you been smoking 10 or more cigarettes a day for the past 6 months?
If you are a female between the ages of 18 and 65, you may be eligible to participate in
our research study at no cost to you. The study involves an 8-week smoking cessation
phase, where you will be given free nicotine patches to help you quit smoking. If you are
able to successfully quit smoking after 7 weeks of nicotine replacement therapy (i.e. the
patch), you will enter into the 5-week relapse prevention phase of the study where you
will stop using the patch, and you will be randomly assigned to receive an investigational
drug that may be an effective treatment in helping prevent recently quit smokers from
relapsing or placebo (i.e. inactive medication).
Study participation involves weekly or biweekly visits to our clinic at Massachusetts
General Hospital and the completion of computerized and behavioral tasks at three points
throughout the 15-week study. Additional compensation will be provided.
If interested, please call 617-724-8472 or email quitforgood@partners.org. All inquiries
are completely confidential.
IRB #2006-P-000031
3. Cognitive-Behavior Therapy for Depression in Bipolar Disorder
The MGH Bipolar Clinic and Research Program is currently seeking volunteers to
participate in a research study evaluating a psychosocial therapy for the treatment of
depressive symptoms in patients with bipolar disorder. In this study, patients will receive
18 sessions of therapy for bipolar depression and a brain scan at no cost.
Bipolar patients above the age of 18, who are currently in a depressive episode, please
contact Hannah Lund at hlund@partners.org or call (617) 724-6545 for more
information. IRB # 2006-P-001521
4. Women with Heart Disease
Researchers at Massachusetts General Hospital in Boston, MA are currently enrolling
women who suffer from chest pain due to heart disease. If you have had a prior bypass
graft or stent procedure but still have chest pain that limits your day-to-day activities, are
taking at least 2 medications for your chest pain, and can take an exercise treadmill test,
you may be eligible to enroll in this research study. The study includes 2-3 screening
visits, 6 study visits, and yearly phone follow-up for four years. The study will reimburse
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out-of-pocket expenses. If you are interested in participating or would like more
information please contact Voula Christopoulos, the research coordinator, at 617-6432890 or by e-mail at vchristopoulos1@partners.org. IRB# 2007-P-001075
5. Researchers from Brigham and Women’s hospital are seeking men and women
who are suffering from tunnel vision. If you are between the age of 21 and 65 and
cannot see as wide or complete a field of vision as normal, you may qualify for a research
study. Eligible candidates will be asked to come to Birgham and Women’s Hospital for a
single visit, which consists of answering brief questionnaires, and being given a
functional magnetic resonance imaging (fMRI) scan of the brain.
For more information please contact Zvi at 617-732-5969 or zshapiro@partners.org.
IRB# 2007-P-000109
6. Weight Loss Study for patients with type-II diabetes
The MGH Weight Center is seeking eligible participants to take part in a clinical trial for
an experimental weight loss medication. We are looking for people who are overweight
or obese and have type-II diabetes. Study related exams and drug as well as individual
nutritional counseling will be provided free of charge for those who qualify.
You may be eligible to participate in this investigational research study if you:
Are between 18 and 65 years old
Have type-II (adult onset) diabetes treated with oral medications only (no insulin)
Are overweight
Are not pregnant or planning to become pregnant in the next year
For more information visit http://www.weightcenter.org/ or call 617-724-9616 IRB#
2007-p-002197
7. General Anesthesia Study
The Mass General Hospital Department of Anesthesia and Critical Care is recruiting
healthy, non-smoking adults, ages 18-36 years for a research study to identify the sites of
action of Propofol anesthesia in the brain. We will be using magnetic resonance imaging
(MRI) and electroencephalogram (EEG) to observe brain activity. Studies will be
conducted at the MGH General Clinical Research Center in the Charlestown Navy Yard,
and will consist of a physical exam and a 7-hour imaging/EEG/anesthesia session. Two
or three visits will be required to complete the study. Subjects will receive up to $200 for
completion of the study. For more information, please contact Dr. Emery N. Brown in the
MGH Department of Anesthesia and Critical Care at 617-724-9857 or at
mgh.anesthesia.study@gmail.com.http://neurostat.mgh.harvard.edu/anesthesia_eeg.htm.
IRB #: 2005-P-001549
8. Volunteers Needed for MRI Research Study on Depression:
Caucasian women ages 30-44 with a history of depression who are no longer depressed
are needed for a research study on hormone and brain activity in depression. This
research study involves two 4 1/2 hour visits, two weeks apart, to our imaging center at
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Brigham and Women's Hospital. Both visits will include an MRI scan, blood draws, and
some questionnaires and cognitive (thinking processes) testing. You will receive up to
$250 compensation for your participation in the two visits. If you would like to learn
more about the research study, please call our depression study coordinator, Dr. Laura
Holsen, at 617-525-8772. IRB #: 2006P-001172
9. Are you a current or former cigarette smoker?
We are looking for current and former cigarette smokers to participate in a one-day study
(~3 hours) to help determine the risk factors for developing COPD (Chronic Obstructive
Pulmonary Disease). You may be eligible if you are:



A current or former smoker
Between 45 and 80 years of age
White (Non-Hispanic) or African American
Compensation provided.
For more information please call 1-866-328-9494 or email copdstudy@partners.org.
IRB# 2007-p-000554
10. Weight Loss Study
The MGH Weight Center is seeking eligible participants to take part in a clinical trial for
an experimental weight loss medication. Study related exams and drug as well as
individual nutritional counseling will be provided free of charge for those who qualify.
You may be eligible to participate in this investigational research study if you:
Are between 18 and 65 years old
Are not diabetic
Are overweight
Are not pregnant of planning to become pregnant in the next year
For more information visit http://www.weightcenter.org/ or call 617-724-9616 IRB#
2008-p-000193
11. Depression, Inflammation and measures of aging
We are looking for participants in a research study examining how depression with or
without anxiety impacts inflammation and measures of aging. We are trying to
understand the relationship between stress related to suffering from depression and how it
may cause cells in the body to age, and thus impact long term health. You may be eligible
if:
1. You are currently depressed and are not currently taking an anti-depressant
medication.
2. You are between 18 and 70 years of age.
This study would involve having a formal psychiatric interview, filling out some
questionnaires and having a blood draw. We may ask you to return 4 times over the next
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8 years to repeat the same procedure. There is no treatment offered in this study, but this
study can be done in conjunction with several treatment studies at our program.
Procedures will take about 2 and ½ hours each visit, and participants will be paid up to
$75 per visit for their time and effort. If you are interested, please call us at 617-7265805.
IRB# 2007-P-000123
12. Do you have Atrial Fibrillation?
Researchers at the Massachusetts General Hospital are seeking people with Atrial
Fibrillation to take part in a study about AF. Participants will be interviewed, have an ecg
taken, and give a one time blood sample. Participation involves one brief visit to the
MGH.
To find out more information please call Marisa Shea, RN, study nurse, at 617-724-7780.
IRB # 2001-P-000053
13. Women with anorexia nervosa who are 18-45 years old and have not had their
period for at least 3 months, are needed for a research study at Massachusetts General
Hospital looking at the role of cortisol and other hormones on skeletal health.
Participants cannot be on oral contraceptive pills. The study includes an hour-long
screening session, a two-hour outpatient visit and a 24-hour inpatient stay. Participants
receive a physical examination, nutritional and body composition analyses, and a
hormonal evaluation, as well as bone density, blood, urine and saliva tests at no cost. For
more information contact Janet Lydecker at (617) 724-1838 or jlydecker@partners.org.
Volunteers also receive up to $150 for their participation, as well as reimbursement of
local travel/ parking costs. IRB# 2003-p-000549
14. MRI Research Study
MGH Department of Neurology & Martinos Center for Biomedical Imaging in
Charlestown Navy Yard seek young, middle-aged, and older adults (ages 18 and older)
for a research study looking at characteristics of normal aging and examining changes in
the brain and cognition (thinking) in Alzheimer's and Huntington's Diseases. Study
includes a brief medical history, 90 minute neuropsychological exam, and 2 hour imaging
session. Magnetic resonance imaging (MRI) will be used to examine brain structure, and
to see how the brain responds while performing a memory task. Payment for
participation: $50 per session for each of the two sessions (MRI/cognitive testing). For
more information, please leave a message for Dr. Diana Rosas at 617-726-5486 or email
cenagn@nmr.mgh.harvard.edu IRB# 2002-p-000137
15. Healthy Subjects Who Have Experienced Trauma Wanted For
A Study of Brain Activity in People with Posttraumatic Stress Disorder (PTSD)
Dr. Lisa Shin and colleagues in the Department of Psychiatry at the Massachusetts
General Hospital (MGH) are conducting a research study to examine brain activity in
individuals who have posttraumatic stress disorder (PTSD), as compared to those who do
not have PTSD. We are seeking healthy comparison subjects who have experienced
traumatic events in the past. Participation will take up to 5 hours of your time. It will
involve undergoing a psychiatric assessment, filling out questionnaires, providing a saliva
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sample, and lying in a scanner while “pictures” of your brain are taken using functional
magnetic resonance imaging (fMRI). Participants will be paid $100 for their time.
Who is Eligible: Individuals who are:
Age 18-45
Right-Handed
Not Pregnant
Without metal implants, such as pacemakers and aneurysm clips
For more information: Please contact Lisa M. Shin, PhD at (617) 726-8120IRB# 2006-P000579/4
16. Weight Loss Study
Doctors at the MGH Weight Center are seeking eligible participants to take part in a
clinical research study with an experimental drug for the treatment of obesity and type-II
diabetes. Study related exams and drug as well as individual nutritional counseling will
be provided free of charge for those who qualify.
You may be eligible to participate in this investigational research study if you:
Are between 18 and 65 years old
Have Type-II (adult onset) diabetes
Are overweight
Are not pregnant of planning to become pregnant in the next year
For more information visit http://www.weightcenter.org/ or call 617-724-9616 IRB#
2007-p-2197
17. Do you get out of bed to eat at night, after you have gone to sleep?
Do episodes of repetitive eating at night feel out of your control? You may have SleepRelated Eating Disorder, which can disrupt your sleep and health. Brigham and Women’s
Hospital Sleep Health Center in Brighton is conducting a research study on an
investigational medication for Sleep-Related Eating Disorder. Qualified participants can
receive up to $300 for 10 clinic visits over 4 months. If interested, please call Lisa at
(617) 783-1496 x115, or email SleepResearch@sleephealth.com IRB # 2007-P-002187
18. Healthy Women Wanted for Research Study:
The MGH Reproductive Endocrine Unit seeks:
 36-45 years old
 Who have Regular menstrual cycles (25-35 days)
 Who are not on any medications (including birth control pills)
 Volunteers will be remunerated up to $400
This 2-3 week study does not require an overnight stay in the hospital or involve any
investigational drug.
If interested, please call Teresa at 617-726-8484 or email talati@partners.org IRB# 2002P-001354
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