Margaret R. Becklake, MD - Curriculum Vitae – CURRICULUM VITAE 1 MARGARET R. BECKLAKE, MD Address: Respiratory Epidemiology and Clinical Research Unit Joint Departments of Epidemiology and Biostatistics, Occupational Health Faculty of Medicine, McGill University Montréal Chest Institute, Room K1.33 3650 St Urbain Street, Montréal, Québec Canada H2X 2P4 Tel: (514) 934-1934 ext 32159 Fax: (514) 843-2803 Email: margaret.becklake@mcgill.ca Citizenship: Canadian Degrees, Professional Qualifications 1. 2. 3. 4. 5. 6. 7. MB, BCh., University of the Witwatersrand, Johannesburg, South Africa MD, University of the Witwatersrand, Johannesburg, South Africa M.R.C.P., London, England F.R.C.P., London, England Registered Physician Specialist, South African Medical and Dental Council Certified Specialist, Chest Diseases and Tuberculosis, Québec Certified Specialist, Community Health, Québec 1944 1951 1946 1972 1954 1965 1981 Post Graduate Training 1. 2. 3. 4. Internship in Medicine and Surgery, Johannesburg General Hospital 1945 Student and Intern in Medicine, Post-graduate Medical School of London, England 1946 Research Assistant, then Junior Medical Registrar (research) at the Post-graduate 1948-1949 Medical School of London, England Medical Registrar (tutorial), University of the Witwatersrand at Johannesburg 1950-1954 General Hospital (this post carried the University status of Junior Lecturer in Medicine) Academic Appointments 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. Lecturer in Clinical Pathology, University of the Witwatersrand 1947 Junior Lecturer in Medicine, University of the Witwatersrand 1950-1957 Assistant Professor, Experimental Medicine, McGill University 1961-1965 Associate Professor, Experimental Medicine, McGill University 1965-1971 Professor, Experimental Medicine and Medicine, McGill University 1972- date Associate Professor, Epidemiology and Health, McGill University 1967-1972 Professor, Epidemiology and Biostatistics, McGill University 1973- date Associate member, School of Occupational Health, McGill University 1983- date Professor (honorary), Community Health, University of the Witwatersrand, 1984-1985 Johannesburg (while on sabbatical leave from McGill University) Director, Respiratory Epidemiology Unit 1992-1998 Member, Respiratory Epidemiology and Clinical Research Unit 1998 to date Director, Annual Summer Program, Department of Epidemiology and Biostatistics, 1986-1993 McGill University Margaret R. Becklake, MD - Curriculum Vitae – 2 Hospital and Other Appointments 1. 2. 3. 4. 5. 6. 7. 8. 9. Physiologist to the Pneumoconiosis Bureau, Johannesburg, South Africa 1954-1957 Research Bursar, Cardiopulmonary Unit of the Council for Scientific & Industrial 1954-1957 Research, Johannesburg General Hospital Clinical Fellow, Royal Victoria Hospital, Montréal 1958 Clinical Assistant, Royal Victoria Hospital, Montréal 1959-1963 Assistant Physician, Royal Victoria Hospital, Montréal 1964-1966 Associate Physician, Royal Victoria Hospital, Montréal 1967-1973 Senior Physician, Royal Victoria Hospital, Montréal 1974-1989 Head, Epidemiology Unit and Principal Medical Officer, National Centre for 1984-1985 Occupational Health, Johannesburg (while on sabbatical leave from McGill University) Honorary Physician, Royal Victoria Hospital, Montréal 1989-to date Honours and Awards Medical Research Council of Canada: Career Investigator 1968-1993 University of the Witwatersrand, Johannesburg, South Africa: MD(Honorary) 1974 Royal Society of Canada: Fellow 1991 Royal Victoria Hospital: Physician-in-Chief’s Award 1992 South African Pulmonology Society: Honorary Life Membership 1993 College of Medicine of South Africa: Honorary Fellow 1994 McGill University: Professor Emeritus 1996 Canadian Lung Association: Connaught Award for Outstanding Service in Prevention and Control of Lung Disease 1996 American Thoracic Society: Distinguished Achievement Award 1997 American Thoracic Society: World Lung Health Award 2001 Les ambassadrices: Portraits de femmes accomplies au Québec, Nima Mazhari (photographe). Stanké 2001, page 73 2001 University of Massachusetts-Lowell : Doctor of Humane Letters (Honoris Causa) 2003 Professional activities 1. Membership in professional societies: Canadian Society for Clinical Investigation (member) Canadian Thoracic Society (member) Research Awards Committee (member) Executive (member) President American Physiological Society (member) American Thoracic Society (member) Environmental and Occupational Health (EOH) Assembly (member) ditto Long Range Planning Committee 1960- date 1964- date 1968-1973 1977-1978 1978-1979 1968-2002 1964 -date 1977 -date 1979-81, 1991-94 Margaret R. Becklake, MD - Curriculum Vitae – 2. International Respiratory Epidemiology Courses Sponsored or co-sponsored by: International Union Against Tuberculosis and Lung Disease (IUATLD) and/or The American Thoracic Society (ATS) Faculty and Co-Curriculum Director with Professor J. Samet, Mexico City (IUATLD/ATS) March 21-28, 1994 Research Methods for the Promotion of Lung Health Faculty and Curriculum Director, Nairobi, Kenya (IUATLD/ATS) Dec 4-9, 1995 Faculty and Curriculum Director, Nairobi, Kenya (IUATLD/ATS) Dec 2-7, 1996 Faculty and Co-Curriculum Director, Aberdare, Kenya (IUATLD) Mar 8-16, 1998 Faculty and Co-Curriculum Director, Valley of a Thousand Hills, South Africa (IUATLD/ South African Pulmonology Society) Sept 5-10, 1999 Faculty and Co-Curriculum Director, Aberdare, Kenya (IUATLD) Apr 6-12, 2002 Basic techniques in lung health, Paris, Faculty (IUATLD) October 2, 1996 Basic techniques in lung health, Madrid, Faculty (IUATLD) Sept 15, 1999 International Respiratory Epidemiology Course (Basic) Faculty (ATS /Sociedad Chilena de Enfermadades Respiratorias) Quinamivada, Chili Nov 27-Dec 2, 2000 3. Professional service: College of Physicians and Surgeons of Quebec Board of Examiners in the specialty of Respiratory Disease Vice-president 1971-1974 President 1975-1977 National Heart Lung and Blood Institute, National Institutes of Health, Washington, DC Pulmonary Training Committee (member) 1972-1974 Site visit teams (member) 1981,1986 Parent Committee, SCOR grant (member) 1986 Lung Health Study: Member, Data Safety and Monitoring Board 1990-1994 Medical Research Council of Canada (member) 1975-1980 Executive Committee (member) 1975-1977 Conseil de Recherche en Santé du Québec Membre, Comité de la recherche thématique sur la santé et la sécurité au travail 1978-1981 Institut de Recherche en Santé et Sécurité au Travail Membre, Conseil scientifique 1981-1983 Royal College of Physicians and Surgeons of Canada Membre du jury d'examens en médecine du travail 1988-1998 Fonds de Recherche en Santé du Québec Membre, Conseil d'administration 1991-1998 World Health Organization/International Labour Office Sept. 21-23, 1993 Temporary Advisor and Chair of meeting to develop "Guidelines on Medical Screening and Surveillance of Workers Exposed to Mineral Dust” New Zealand Asbestos Register (Wellington, NZ), Consultant Nov 16-24, 1994 University of Campinas, Brazil (Dept. Preventive and Social Medicine), Consultant 1999-date Morbidity and Mortality among Workers and Ex-Workers exposed to Asbestos In Mining-Milling Activity 1940-1996. Project Coordinator: Prof E. Bagatin 3 Margaret R. Becklake, MD - Curriculum Vitae – 4 Reviewer on request for grant applications 1980-date Medical Research Council of Canada; National Health Research Development Program; Fonds de Recherche en Santé du Québec; Ontario, Alberta and British Columbia Medical Research Councils; BC Occupational Health Council: New Zealand Child Development Program, Canadian Institutes for Health Research Editorial activities Canadian Journal of Physiology and Pharmacology Associate Editor 1970-1973 American Review of Respiratory Disease Member, Editorial Board 1970-78 and 1982-88 American Journal of Industrial Medicine Member, Editorial Board 1975- 1998 International Journal of Tuberculosis and Lung Disease, Associate Editor 1997-date Canadian Respiratory Journal, Member, Editorial Board 1996- date Journal of Environmental Medicine, Member, Editorial Board 1999-2000 Reviewer on request for the following journals: 1975-date American Journal of Epidemiology; American Journal of Respiratory and Critical Care Medicine (formerly the American Review of Respiratory Disease); Chest; Clinical and Investigative Medicine; European Respiratory Journal; International Journal of Epidemiology; Journal of Applied Physiology; Journal of Clinical Epidemiology (formerly Journal of Chronic Diseases); Lung; New England Journal of Medicine; Scandinavian Journal of Work Environment and Health; Revue des Maladies Respiratoires Margaret R. Becklake, MD - Curriculum Vitae – 5 Trainees supervised,*co-supervised,**or on their thesis committee*** within the last 10 years Trainee Period Degree Zwi,* Anthony+ 84-94 PhD 94 University of Witwatersrand Community Health Respiratory health of foundry workers Assoc Prof, London School of Tropical Medicine and Hygiene UK Mokeotle, * Khathatso + 85-90 MSc 90 University of Witwatersrand Community Health Respiratory health survey of an urban Black Workforce in Johannesburg Director, Progressive Primary Health Care Network, Johannesburg, South Africa Lalloo,** * Umesh + 85-92 MD 92 Univ.of Natal, Durban, S Africa Respiratory health survey of a South African Indian community Professor/Chair, Dept.of Medicine University of Natal, Durban, S Africa Delfino,* Ralph 88-93 PhD Epidemi ology 93 McGill; Respir Epidemiol Unit Urgent hospital admission and air pollution levels Associate Clinical Professor, University California, Irvine DeGrosbo is*, Sylvie 90-98 PhD Epidemi ology 98 McGill; Respir Epidemiol Unit Occupational exposures and airway disease Zejda,* Jan 89 90 McGill; Respir Epidemiol Unit Jaakkola, * Maritta 87 Diploma Epidemi ology Diploma Epidemi ology 90 McGill; Respir Epidemiol Unit Sallie,** Beverly 93 Diploma Epidemi ology 94 McGill Occupational exp-osure to asbestos & chronic airways disease Cigarette smoking & change in ventilatory lung function over time in young adults. Circumstances, severity and after effects of inhalation accidents Agente de recherche Centre Etudes InterActions Biologiques UQAM Dean, Faculty of Public Health, University of Silesia, Sosnowic, Poland Associate Physician, Institute of Occupational Health, Helsinki, Finland. Odhiambo *, Joseph 92-94 Diploma Epidemi ology 94 McGill; Respir Epidemiol Unit Urban-rural respiratory health surveys in Kenya Director, KEMRI#, Consulltant, USAIDS Kenya Ng’ang’a, Lucy 92-96 PhD Epidemi ology 96 McGill; Respir Epidemiol Unit Epidemiology of childhood asthma in Kenya KEMRI: IUATLD Collab Centre; Consultant, USAIDS Kenya Eltayara, Loubna 93-96 Diploma Epidemi ology 96 McGill; Meakins Christie Labs Relationship between dyspnea &expiratory flow limitation Chest disease, Beirut + # ## Yr Institution; Dept or Unit Thesis Title Former or current position Research Assistant Imperial College, London, UK Supervision started, when I was on sabbatical leave at the University of Witwatersrand, Johannesburg, South Africa, 1984-85 Kenya Medical Research Institute IUATLD: International Union Against Tuberculosis and Lung Disease Margaret R. Becklake, MD - Curriculum Vitae – 6 Trainees supervised*, co-supervised** or member of their thesis committee*** within the last 10 years:(continued) Trainee Period Degree Yr Institution; Dept or unit Chen,* Bowen 95-96 Diploma Epidemi ology 96 McGill; Respir Epi Unit Risk factors for pneumonia death in children under 5 Child health, Univ. Beijing, China Mungai,*** Mary 95-97 MSc Epidemi ology 97 McGill; Respir Epi Unit Epidemiology of atopy in Kenyan children USPHS:CDC: Field service trainee Kassaye,** Tarik 95-00 PhD 01 McGill; Dietetics Vit A supplementation & lung function in Ethiopian children Relationship of the home environment to indicators of asthma in Montréal and Port Alberni Exposure to occupational agents as a risk factor for adult asthma Post Doctoral Fellow, Harvard School of Public Health University of Northern British Columbia McGill Incidence of ccupational asthma in UK surveillance system Research Asst; Imperial College, Univ. London, UK McGill Exposure to allergens in early life Research Assistant Imperial College Univ London, UK Discordance between cross sectional & longitudinal estimates for the effect of ageing on lung function Respiratory health among South African coal miners Validation of an online questionnaire in a population of adolescents Professor of Occupational Respiratory Medicine Univ Newcastle-on-Tyne, UK & Human Nutrition Mitri,*** Angeli 95-98 99-00 MSc 00 Demir,* Ahmet 96-98 MSc 98 McGill, Respir Epi Unit McGill, Respir Epi Unit Keynes**, Helen 97 Diploma Harris,* Jessica 98 Diploma Hendrick,** David 98 MSc 01 McGill; Joint Depts of Epi, Biostatistics, & Occ Hlth Naidoo,*** Rajan 98 PhD 02 University of Michigan, USA Radon *** Katja 98 MSc 02 McGill; Joint Depts of Epi, Biostatistics, & Occ Hlth 99 Thesis Title Former or current position Chest Physician, Dept Medicine, Haceteppe Univ.Ankara, Turkey Dept of Community Health, University of Natal, Durban Institute of Occupational and Environmental Medicine, Munich Margaret R. Becklake, MD - Curriculum Vitae – 7 PUBLICATIONS A) Articles in peer-reviewed journals 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. Van Lingen B, Becklake, MR. Venous catheterization of the heart; results on normal subjects. S Afr Med J 1948; 12:575-584. Briscoe WA, Becklake MR, Rose TF. Intrapulmonary mixing of helium in normal and emphysematous subjects. Clin Sci 1951; 10:37-51. Becklake MR. A study of an open circuit method: the intrapulmonary mixing of inspired air. Thorax 1951; 6:433-441. Becklake MR. A new index of the intrapulmonary mixture of inspired air. Thorax 1952; 7:111-116 Becklake MR, Goldman HI. The clinical uses of pulmonary function tests. S Afr Med J 1953; 27:16-19. Becklake MR, McGregor M, Goldman HI, Braudo JL. A study of the effects of physiotherapy in chronic hypertrophic emphysema. Dis Chest 1954; 26:2-12. Becklake MR, Goldman HI, McGregor M. The effect of pneumoperitoneum on lung function tests in chronic hypertrophic emphysema. Thorax 1954; 9:222-225. Becklake MR, Goldman HI. The influence of pulmonary dead space on lung mixing indices. S Afr J Med Sci 1954; 19:21-27. Becklake MR, Goldman HI. The prediction of pulmonary dead space. Acta Med Scand 1955; 306:1519. Becklake MR, Griffiths SB, McGregor M, Goldman HI, Schreve JP. Oxygen dissociation curves in sickle cell anaemia and in patients with the sickle cell trait. J Clin Invest 1955; 34:751-755. Becklake MR. A functional approach to the diagnosis of chest disease. The Leech 1956; 26:27-30. Becklake MR, Goldman HI, Freed OG, Bosman AR. The long-term effects of exposure to nitrous fumes. Am Rev Tubercul Pulm Dis 1957; 76:398-409. Becklake MR, DuPreez L, Lutz W. Lung function in silicosis of the Witwatersrand goldminer. Am Rev Tubercul Pulm Dis 1958; 77:400-412. Zwi S, Becklake MR. Respiratory function of Witwatersrand goldminers: a comparison between radiologically normal miners and control non-mining subjects. Br J Ind Med 1959; 16:290-296. Kamener R, Becklake MR, Goldman HI, McGregor M. Respiratory function following segmental resection of the lung for bronchiectasis. Am Rev Tubercul Pulm Dis 1958; 77:209-221. Goldman HI, Becklake MR. Respiratory function tests: normal values at median, and the prediction of normal results. Am Rev Tubercul Pulm Dis 1959; 79:457-467. Zwi S, Theron JC, McGregor M, Becklake MR. The influence of instrumental resistance on the maximum breathing capacity. Dis Chest 1959; 36:361-368. Becklake MR, Zwi S, Lutz WH. Studies on the nature and aetiology of the respiratory disability in Witwatersrand gold miners free of radiological silicosis. Br J Ind Med 1959; 16:290-296. McGregor M, Becklake M. The relationship of O2 cost of breathing to respiratory mechanical work and respiratory force. J Clin Invest 1961; 40:971-980. Beaudry PH, Becklake MR. A trial of SA-97 in the treatment of asthma in children. J Allergy 1962; 33:210-214. Macklem PT, Becklake MR, The relationship between the mechanical and diffusing properties of the lung. Am Rev Respir Dis 1963; 87:47-56. Becklake MR, Varvis CJ, Pengelly LD, Kenning S, McGregor M, Bates DV. The measurement of pulmonary blood flow during exercise using nitrous oxide. J Appl Physiol 1962; 17:5279-5286 Newhouse MT, Becklake MR, Macklem PT, McGregor M. Effect of alterations in CO2 tension on flow resistance. J Appl Physiol 1964; 19:745-749. Parsons LD, de Villiers AJ, Bartlett LS, Becklake MR. Lung cancer in a fluorspar mining community. II. The prevalence of symptoms and disability. Br J Ind Med 1964; 21:110-116. Becklake MR, Frank H, Dagenais GR, Ostiguy GL, Guzman CA. The influence of age and sex on exercise cardiac output. J Appl Physiol 1965; 20:938-947. Andrew GM, Guzman CA, Becklake MR. Effect of athletic training on exercise cardiac output. J Appl Margaret R. Becklake, MD - Curriculum Vitae – 27. 28. 29. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. 48. 49. 50. 51. 52. 53. 8 Physiol 1966; 21:603-608. Ostiguy GL, Becklake MR. Solubility of nitrous oxide in human blood. J Appl Physiol 1966; 21:13971399. White JJ, Tanser PH, Anthonisen NR, Wyands JC, Pare JAP, Becklake MR, Munro DD, Maclean LD. Human lung homotransplantation. Can Med Assoc J 1966; 94:1199-12-19. Holley S, Milic-Emili J, Becklake MR, Bates DV. Regional distribution on ventilation and perfusion in obesity. J Clin Invest 1967; 46:475-481.Massey DG, Becklake MR, McKenzie JM, Bates DV. Circulatory and ventilatory response to exercise in thyrotoxicosis. N Engl J Med 1967; 276:1104-1112. Douglas FGV, Becklake MR. Effect of seasonal training on maximal cardiac output. J Appl Physiol 1968; 25:600-605. Douglas FGV, Cocco J, Brindle F, Gilbert RGB, Becklake MR. Pulmonary mechanics and gas exchange during neurosurgical anesthesia. Can Anaesth Soc J 1969; 16:7-17. Ouellet Y, Poh SC, Becklake MR. Circulatory factors limiting maximal aerobic exercise capacity. J Appl Physiol 1969: 27:874-880. Housley E, Louzada N, Becklake MR To sigh or not to sigh. Am Rev Respir Dis 1970; 101:611-614. Klassen GA, Andrew GM, Becklake MR. Effect of training on total and regional blood flow and metabolism in paddlers. J Appl Physiol 1970; 28:397-406. Becklake MR (Guest Editor). Respiratory function tests in epidemiological surveys. Bull Physiopathol Respir1970; 6:533-535. Becklake MR, Fournier-Massey G, McDonald JC, Siemiatycki J, Rossiter CE. Lung function in relation to radiographic changes in Quebec asbestos workers. Bull Physiopathol Respir 1970; 6:637-660. Fournier-Massey G, Becklake MR. II. Appendice: Epreuves de fonction respiratoire. Bull Physiopathol Respir 1970; 6:661-670. Jodoin G, Gibbs GW, Macklem PT, McDonald JC, Becklake MR. Early effects of asbestos exposure on lung function. Am Rev Respir Dis 1971; 104:525-535. Craig DB, Wahba WH, Don HF, Couture JC, Becklake MR. "Closing Volume" and its relationship to gas exchange in the seated and supine positions. J Appl Physiol 1971; 31:717-721. Wahba WM, Craig DB, Don HF, Becklake MR. The cardio-respiratory effects of thoracic epidural anesthesia. Can Anaesth Soc J 1972; 19: Jan. No.I. Andrew GM, Becklake MR, Guleria JS, Bates DV. Heart and lung functions in swimmers and nonathletes during growth. J Appl Physiol 1972; 32:245-251. McDonald JC, Becklake MR, Fournier-Massey G, Rossiter CE. Respiratory symptoms in chrysotile asbestos mine & mill workers of Quebec. Arch Environ Health 1972; 24: 357-363. Becklake MR, Fournier-Massey G, Rossiter CE, McDonald JC. Lung function in chrysotile asbestos mine and mill workers in Quebec. Arch Environ Health 1972; 24:401-409. Demedts M, Sniderman A, Utz G, Palmer WH, Becklake MR. Lung volume including closing volume and arterial blood gas measurements. Bull Physiopathol Respir 1974; 10:11-25. Seely JE, Guzman CA, Becklake MR. Heart and lung function at rest and during exercise in adolescence. J Appl Physiol 1974; 36:34-40. McDonald JC, Becklake MR, Gibbs GW, McDonald AD, Rossiter CE. The health of chrysotile mine and mill workers of Quebec. Arch Environ Health 1974; 28:61-68. Jeffrey JR, Guttman RD, Becklake MR, Beaudoin JG, Morehouse DD. Recovery from severe cytomegalovirus pneumonia in a renal transplant patient. Am Rev Respir Dis 1974; 109:129-133. McGregor M, Becklake MR. Basic research in acupuncture analgesia. Can Med Assoc J 1974; 110:328329. White FMM, Swift J, Becklake MR, Rheumatic complaints and pulmonary response to chrysotile dust inhalation in the mines and mills of Quebec. Can Med Assoc J 1974; 111:533-535. Fournier-Massey G, Becklake MR. Pulmonary function profiles in Quebec asbestos workers. Bull Physiopathol Respir 1975; 11:429-445. Becklake MR, Leclerc M, Strobach H, Swift J. The N2 closing volume test in population studies: sources of variation and reproducibility. Am Rev Respir Dis 1975; 111:141-147. Becklake MR. Respiratory impairment including assessment of disability. Bull Physiopathol Respir Margaret R. Becklake, MD - Curriculum Vitae – 54. 55. 56. 57. 58. 59. 60. 61. 62. 63. 64. 65. 66. 67. 68. 69. 70. 71. 72. 73. 74. 75. 76. 77. 78. 79. 9 1975; 11:203-209. Becklake MR, Fournier-Massey G, Black R, Lung function profiles in the chrysotile asbestos mines and mills of Quebec. Chest 1976; 69 (2 suppl): 303. Becklake MR. State of the Art: Asbestos-related diseases of the lung and other organs: their epidemiology and implications for clinical practice. Am Rev Respir Dis 1976; 114:187-227. Becklake MR, Soucie J, Gibbs GW, Ghezzo H. Respiratory health status of children in three Quebec urban communities: an epidemiologic study. Bull Physiopathol Respir 1978; 14:205-218. Macklem PT, Becklake MR. Is screening for chronic airflow limitation desirable? Chest 1978; 74:607608. Becklake MR, Clinical measurements in Quebec chrysotile miners: use for future protection of workers. Ann NY Acad Sci 1979; 330:23-30. Becklake MR, Liddell FDK, Manfreda J, McDonald JC. Radiological changes after withdrawal from asbestos exposure. Br J Ind Med 1979; 36:23-28. Aubry F, Gibbs GW, Becklake MR. Air pollution and health in three urban communities. Arch Environ Health 1979; 34:360-68. Becklake MR. Environmental exposure to asbestos: a factor in the rising rate of cancer in the industrialized world? Chest 1979; 76:285-92. Becklake MR. Asbestos and lung cancer: the clinicians' questions. Chest 1980; 78:372-373. Hurwitz S, Ross J, Liben A, Becklake MR. Lung function in young adults: evidence for differences in chronological age at which various functions start to decline. Thorax 1980; 35:615-619. Becklake MR. Summary, 23rd Aspen Lung Conference on the Environment and the Lung. Chest 1981; 80:90S-95S. Becklake MR, Occupational respiratory diseases in technically advanced countries. Bull Int Union Tuberc 1981; 56:12-15. Cohen D, Crowther TS, Gibbs GW, Becklake MR. Magnetic lung measurements in relation to occupational exposure in asbestos miners and millers of Quebec. Environ Res 1981; 26:535-550. Rea H, Becklake MR, Ghezzo H. Lung function changes as a reflection of tissue aging in young adults. Bull Physio-pathol Resp 1982; 18:5-19. Becklake MR, Thomas DT, Liddell FDK, McDonald JC. Follow-up respiratory measurements in Quebec chrysotile asbestos miners and millers. Scand J Work Environ Health 1982; 9(Supp 1):105-110. Becklake MR. Exposure to asbestos & human disease. N Engl J Med 1982; 306:1480-1482. Becklake MR, Asbestos-related diseases of the lungs and pleura: current clinical issues. Am Rev Respir Dis 1982; 126:187-194. Leech JA, Ghezzo H, Stevens D, Becklake MR. Respiratory pressures and function in young adults. Am Rev Respir Dis 1983; 128:17-23. Becklake MR, Toyota B, Stewart M, Hanson R, Hanley J. Lung structure as a risk factor in adverse pulmonary responses to asbestos exposure: a case-referent study in Quebec chrysotile miners and millers. Am Rev Respir Dis 1983; 128:385-388. Becklake MR. Occupational lung disease - past record and future trends using the asbestos case as an example. Clin Invest Med 1983; 6:305-317. Becklake MR. Organic and functional impairment: overall perspective. Am Rev Respir Dis 1984; 129:2(Part2) 96S-100S. Davies JCA, Becklake MR. Reference values for lung function - more to be done. S Afr Med J 1984; 66:830. Becklake MR, Use of information: environmental standards, assessment of risk, prevention and clinical implications. In. Proc Occ Lung Dis Seminar. Med J Australia 1985; 143:63-64. Becklake MR, Occupational and environmental lung disease. Chronic airflow limitation: its relationship to work in dusty occupations. Chest 1985; 88:608-617. Leech JA, Ernst P, Rogala EJ, Gurr RN, Gordon I, Becklake MR. Cardiorespiratory status in relation to mild deformity in adolescent idiopathic scoliosis. J Pediatr 1985; 106:143-149. Copes R, Thomas D, Becklake MR. Temporal patterns of exposure to asbestos and non-malignant pulmonary abnormality in Quebec chrysotile workers. Arch Environ Health 1985; 40:80-87. Margaret R. Becklake, MD - Curriculum Vitae – 80. 81. 82. 83. 84. 85. 86. 87. 88. 89. 90. 91. 92. 93. 94. 95. 96. 97. 10 Becklake MR, Davies JCA. Action on mesothelioma. S Afr Med J 1985; 67:118. Leech JA, Martz L, Liben A, Becklake MR. Diffusing capacity for carbon monoxide: the effects of different derivations of breathhold time and alveolar volume and of carbon monoxide back pressure on calculated results. Am Rev Respir Dis 1985; 132:1127-1129. Picado C, Ernst P, Becklake MR. Lack of an association between social drinking and respiratory health in young Canadians. Can J Public Health 1985; 76:134-135. Becklake MR. Occupational lung disease in the 1980's: an approach to its identification. S Afr J Continuing Med Education 1986; 4:29-36. Ernst P, Thomas D, Becklake MR. Respiratory survey of North American Indian children living in proximity to an aluminium smelter. Am Rev Respir Dis 1986; 133:307-312. Becklake MR. Concepts of normality applied to the measurement of lung function. Am J Med 1986; 80:1158-1164 Steinberg M, Becklake MR. Socio-environmental factors and lung function; a review of the literature. S Afr Med J 1986; 70:270-274. Murphy RL, Becklake MR, Brooks SM, Gaensler EA, Gee Bl, Goldman AM, Kleinerman JI, Lewinsohn HC, Mitchell RS, Utell MJ, Weill H, The diagnosis of nonmalignant diseases related to Asbestos. Am Rev Respir Dis 1986; 134:363-368. Ernst P, Shapiro S, Dales RE, Becklake MR. The determinants of respiratory symptoms in insulators exposed to asbestos and synthetic mineral fibers. Br J Ind Med 1987; 44:90-95. Picado C, Laporta P, Grassino A, Cosio M, Thibodeau M, Becklake MR, Mechanisms affecting exercise performance testing in subjects with asbestos-related pleural disease. Lung 1987; 165:45-57. Dales RE, Hanley JA, Ernst P, Becklake MR. Computer modelling of measurement error in longitudinal lung function data. J Chron Dis 1987; 40:769-774. Becklake MR, Irwig LM, Kielkowski D, Webster I, de Beer M, Freeman S, Landau SP. The predictors of emphysema in South African gold miners. Am Rev Respir Dis 1987; 135:1234-1241. Becklake MR, Freeman S, Goldsmith C, Hessel PA, Mkhwelo R, Mokoetle K, Reid G, Sitas F. Respiratory questionnaires in occupational studies: their use in multilingual workforces on the Witwatersrand. Int J Epidemiol 1987; 16:606-611. Dales RE, Ernst P, Hanley JA, Battista R, Becklake MR. Prediction of airway reactivity from responses to a standardized respiratory symptom questionnaire. Am Rev Respir Dis 1987; 135:817-821. Becklake MR, Control of asbestos-related disease in the RSA. S Afr Med J 1987; 71:208-210. Masi MA, Hanley JA, Ernst P, Becklake MR. Environmental exposure to tobacco smoke and lung function in young adults. Am Rev Respir Dis 1988; 138:296-299. Sitas F, Davies JCA, Kielkowsi D, Becklake MR. Occupational health services in South African manufacturing industries: a pilot survey. Am J Ind Med 1988; 14:545-557. Martin JR, Muir CF, Moore E, Edwards AC, Becklake MR, Morgan KW, Anderson H, Edstrom H, Rusted IE, Segovia J. Pneumoconiosis in iron ore surface mining in Labrador. J Occup Med 1988; 30:780-784. Margaret R. Becklake, MD - Curriculum Vitae – 98. 99. 100. 101. 102. 103. 104. 105. 106. 107. 108. 109. 110. 111. 112. 113. 114. 115. 116. 117. 118. 119. 120. 121. 122. 123. 11 Utell MJ, Samet JM, Bates DV, Becklake MR, Dockery DW, Leaderer BP, Mauderly JL, Speizer FE, Air pollution and health. Am Rev Respir Dis 1988; 138:1065-1068. Cowie RL, Langton ME, Becklake MR. Pulmonary Tuberculosis in South African gold miners. Am Rev Respir Dis 1989; 139:1086-1089. Becklake MR. Occupational exposures: evidence for a causal association with chronic obstructive pulmonary disease. Am Rev Respir Dis 1989; 140:S85-S91. Becklake MR, Occupational Pollution. Chest 1989; 96(suppl):372S-378S. Zwi AB, Reid G, Landau SP, Kielkowski D, Sitas F, Becklake MR. Mesothelioma in South Africa, 1976-84: Incidence and case characteristics. Int J Epidemiol 1989; 18:320-329. Ernst P, Dales R, Nunes F, Becklake MR. Relation of airway responsiveness to duration of work in a dusty environment. Thorax 1989; 44:116-120. Becklake MR. Epidemiology of spirometric test failure. Brit J Ind Med 1990; 47:73-74. Bourbeau J, Ernst P, Chrome J, Armstrong B, Becklake MR. The relationship between respiratory impairment and asbestos-related pleural abnormality in an active work force. Am Rev Respir Dis 1990; 142:837-842. Becklake MR. Epidemiology and surveillance. Chest 1990; 98:5(suppl):165S-172S. Becklake MR, Lalloo UG, The "healthy smoker": a phenomenon of health selection? Respiration 1990; 57:137-144. Zwi S, Davies JCA, Becklake MR, Goldman HI, Reinach SG, Kallenbach JM. Respiratory health status of children in eastern Transvaal highveld. S Afr Med J 1990; 78:647-653. Becklake MR. Asbestos and other fiber related diseases of the lungs and pleura: distribution and determinants in exposed populations. Chest 1991; 100:248-254. Lalloo UG, Becklake MR, Goldsmith CM. Effect of standing versus sitting position on spirometric indices in healthy subjects. Respiration 1991; 58:122-125. Jaakkola MS, Jaakkola JJK, Ernst P, Becklake MR. Ventilatory lung function in young cigarette smokers: a study of susceptibility. Eur Respir J 1991; 4:643-650. Jaakkola MS, Ernst P, Jaakkola JJK, Ng'ang'a LW, Becklake MR. Effect of cigarette smoking on evolution of ventilatory lung function in young adults: an eight year longitudinal study. Thorax 1991; 46:907-913. Ernst P, Bourbeau J, Becklake MR. Pleural abnormality as a cause of impairment and disability. Ann N Y Acad Sci 1991; 643:157-162. Ng'ang'a LW, Ernst P, Jaakkola MS, Gerardi G, Hanley JH, Becklake MR. Spirometric lung function: distribution and determinants of test failure in a young adult population. Am Rev Respir Dis 1992; 145:48-52. Becklake, MR. The mineral dust diseases. Tuber Lung Dis 1992; 73:13-20. Ernst P, Becklake MR. La "bronchite chronique industrielle" et les programmes de surveillance médicale. Union Médicale du Canada 1992;121:15-16, 18-20. Jaakkola MS, Jaakkola JJK, Ernst P, Becklake MR. Respiratory symptoms in young adults should not be overlooked. Am Rev Respir Dis 1993; 147:359-366. Delfino RJ, Becklake MR, Hanley JA. Reliability of hospital data for population-based studies of air pollution. Arch Environ Health 1993; 48(3):140-146. Becklake MR, White N. Sources of variation in spirometric measurements: identifying the signal and dealing with noise. Occup Med 1993; 8:241-264. Delfino R, Ernst P, Jaakkola MS, Solomon S, Becklake MR. Questionnaire assessments of recent exposure to environmental tobacco smoke in relation to salivary cotinine. Eur Respir J 1993; 6:11041108. Fonn S, Groenveld H, de Beer M, Becklake MR. An environmental and respiratory health survey of workers in a grain mill in the Johannesburg area. Am J Ind Med 1993; 24:387-400. Fonn S, Groenveld H, de Beer M, Becklake MR. Relationship of respiratory health status to grain dust in a Witwatersrand grain mill: comparison of workers' exposure assessments with industrial hygiene survey findings. Am J Ind Med 1993; 24:401-411. Fonn S, Becklake MR. Documentation of ill health effects of occupational exposure to grain dust Margaret R. Becklake, MD - Curriculum Vitae – 124. 125. 126. 127. 128. 129. 130. 131. 132. 133. 134. 135. 136. 137. 138. 139. 140. 141. 142. 143. 144. 145. 12 through sequential, coherent epidemiologic investigation. Scand J Work Environ Health 1994; 20:13-21. Mokoetle K, de Beer M, Becklake MR. A respiratory survey in a black Johannesburg workforce. Thorax 1994; 49:340-346. White NW, Hanley JH, Lalloo UG, Becklake MR. Review and analysis of variation between spirometric values reported in 29 studies of healthy African adults. Am J Respir Crit Care Med 1994; 150:348-355. Delfino RJ, Becklake MR, Hanley JA. The relationship of urgent hospital admissions for respiratory illnesses to photochemical air pollution levels in Montréal. Environ Res 1994; 67:1-19. Delfino RJ, Becklake MR, Hanley JA, Singh B. Estimation of unmeasured particulate air pollution data for an epidemiological study of daily respiratory morbidity. Environ Res 1994; 67:20-38. Becklake MR, Case BW. Fiber burden and asbestos-related lung disease: determinants of dose-response relationships. Am J Respir Crit Care Med 1994; 150:1488-1492. Jaakkola MS, Jaakkola JJK, Becklake MR, Ernst P. Passive smoking and evolution of lung function in young adults. An 8-year longitudinal study. J Clin Epidemiol 1995; 48(3):317-27 Ernst P, Demissie K, Joseph L, Locher U, Becklake MR. Socioeconomic status and indicators of asthma in children; Am J Respir Crit Care Med 1995;152:570-575 Becklake MR, Relationship of acute obstructive airway change to chronic (fixed) obstruction. Thorax 1995; 50(Suppl 1):S16-S21 Becklake MR. International Union Against Tuberculosis and Lung Disease (IUATLD): initiatives in non-tuberculous lung disease. Tuber Lung Dis 1995; 76:493-504 Demissie K, Ernst P, Hanley J, Locher U, Menzies R, Becklake MR.. Socioeconomic status and lung function among primary school children in Canada. Am J Respir Crit Care Med 1996; 153:719-723 Demissie K, Ernst P, Becklake MR.. Socioeconomic status and childhood atopy. Can Respir J 1996; 3(1):53-57 Jaakkola MS, Jaakkola JJK, Becklake MR, Ernst P. Effect of passive smoking on the development of respiratory symptoms in young adults. An 8-year longitudinal study. J Clin Epidemiol 1996; 49(5):58186 Eltayara L, Becklake MR, Volta CA, Milic-Emili J. Relationship between chronic dyspnea and expiratory flow limitation in patients with chronic obstructive pulmonary disease Am J Respir Crit Care Med 1996; 154: 1726-1734. Becklake MR, Broder I, Chan-Yeung M, Dosman JA, Ernst P, Herbert FA, Kennedy SM, Warren PW, Recommendations for reducing the effect of grain dust on the lungs. Can Med Assoc J 1996; 155:13991403. Demissie K, Ernst P, Joseph L, Becklake MR. Birthweight and preterm birth in relation to indicators of childhood asthma. Can Respir J 1997; 4:91-97 Delfino RJ, Murphy-Moulton AM, Burnett RT, Brook JR, Becklake MR. Effects of air pollution on emergency room visits for respiratory illnesses in Montréal, Québec. Am J Respir Crit Care Med 1997;155:568-576 Becklake MR, Ernst P, Environmental factors. Lancet 1997;350(suppl II):10-13 Ng'ang'a LW, Odhiambo JA, Omwega MJ, Gicheha CM, Becklake MR, Menzies R, Mohammed N, Macklem PT. Exercise-induced bronchospasm: a pilot survey in Nairobi school children. East Afr Med J 1997; 74:694-698. Delfino RJ, Murphy-Moulton AM, Becklake MR. Emergency room visits for respiratory illnesses among the elderly in Montréal: Association with low level ozone exposure. Environ Res 1998;76:67-77 Ng’ang’a LW, Odhiambo JA, Mungai MW, Gicheha CM, Nderitu P, Maingri B, Macklem PT, Becklake MR. Prevalence of exercise induced bronchospasm in Kenyan school children: an urban-rural comparison. Thorax 1998:53:0-7 Becklake MR. Airways disease and occupational exposure to particulates not otherwise classified/regulated. Appl Occup Environ Hyg 1998; 13: 586-592 Odhiambo JA, Ng’ang’a LW, Mungai MW, Gicheha CM, Nyamwaya JK, Karimi F, Macklem PT, Becklake MR. Urban-rural differences in questionnaire-derived markers of asthma in Kenyan school children. Eur Respir J 1998; 12:1105-1112 Margaret R. Becklake, MD - Curriculum Vitae – 146. 147. 148. 149. 150. 151. 152. 153. 154. 155. 156. 157. 13 Becklake MR. Narazenia zawodowe jako przyczyna chorob drog oddechowych w swietle anych pochodzacych oraz grup zawodowych (in Polish). Medycyna Pracy 1998;6 (suppl II):7-17 Demissie K, Ernst P, Joseph L, Becklake MR. The role of domestic factors and day-care attendance on lung function of primary school children. Respir Med 1998;92:928-935 Ng’ang’a L, Odhiambo JA, Mungai MW, Gicheha CM, Becklake MR. Urban-rural differences in questionnaire-derived markers of asthma in Kenyan school children. Eur Respir J 1998;12:1105-1112. Becklake, MR, Kauffmann, F. Gender differences in airway behaviour over the human life span. Thorax 1999:54; 1119-1138 Johnson AR, Dimich-Ward HD, Manfreda J, Becklake MR, Ernst P, Sears MR, Bowie DM, Sweet L, Chan-Yeung M. Occupational asthma in adults in six Canadian communities, Am J Resp Crit Care Med 2000; 162:2058-2062 Manfreda J, Becklake MR, Sears MR, Chan-Yeung M, Dimich-Ward H, Sierstad H, Ernst P, Sweet LE, Van Til L, Bowie DM, Anthonisen NRl. Prevalence of asthma symptoms among adults aged 20-44 years in Canada CMAJ 2001; 164:995-1001 Kassaye T, Receveur O, Johns T, Becklake MR. Prevalence of vitamin A deficiency in children aged 69 years in Wukro, northern Ethiopia. Bull World Health Organ 2001; 79:415-422 Kassaye T, Becklake MR, Receveur O, Hanley JA, Johns T. Association between vitamin A status and lung function level in children aged 6-9 years in Wukro wereda, Northern Ethiopia Int J Epidemiol 2001; 30: 457-464 Becklake MR. When the chest x-ray does not tell the whole story Am J Respir Crit Care Med 2001; 164: 1761-1762 Ernst P, Becklake MR, Ghezzo H. Risk factors for bronchial hyperresponsiveness in late childhood and early adolescence. Eur Respir J 2002; 20:635-639. Radon K, Goldberg M, Becklake MR, Pindur U, Hege I. Low acceptance of an internet-based online questionnaire by young adults. Epidemiology 2002; 13; 748-749. Radon K, Goldberg M, Becklake MR. Healthy worker effect in cohort studies on chronic bronchitis. Scand J Work Environ Health 2002; 28:328-332 B) Book chapters or contributions 1. 2. 3. 4. 5. 6. 7. 8. 9. Bates DV, Christie RV (With the assistance of Becklake, MR, R.E. Donevan, R.G. Fraser, J.A.P. Pare and W. Thurlbeck). Pneumoconioses. In: Respiratory function in health and disease. Handbook of Physiology: Respiration Section. Vol. II. Amer Physiological Society, Washington, DC, 1965;16011614. 1965.. Becklake, MR. Chemical and physical diseases of the lung. In. P.B. Beason, W. McDermott,. editors. Cecil-Loeb Textbook of Medicine, 13th ed. Philadelphia: W.B. Saunders 1971; 911-922. Becklake, MR. Chemical and physical irritants in diseases of the lung. In. P.B. Beason, W. McDermott, eds. Cecil-Loeb Textbook of Medicine, 14th ed. Philadelphia: W.B. Saunders 1974;854-867 Becklake, MR. Permutt S. Evaluation of tests of lung function for "screening" for the early detection of chronic obstructive lung disease. In. Macklem PT, Permutt S, eds. The lung in the transition between health and disease. New York: Marcel Dekker 1979; 345-387. Becklake, MR. Physical and chemical irritants. In. Beason PB, McDermott W, Wyngaarden JB, eds, Cecil-Loeb Textbook of Medicine, 15th ed. Philadelphia: W.B. Saunders 1979; 983-1002 Becklake, MR. Asbestos-related fibrosis of the lungs (asbestosis) and pleura. In. Fishman AP, ed. Pulmonary diseases and disorders: Update. New York: McGraw Hill 1982; 167-192. Becklake, MR. Epidemiologic studies in human populations. In. Witichi HP, Brain JD, editors. The toxicology of inhaled materials. Vol. I, Section C, General assessment of toxic effects. Berlin: SpringerVerlag 1985; 115-147. Becklake, MR. The Pneumoconioses. In. Murray JF, Nadel J, eds. Textbook of Respiratory Medicine. Philadelphia: WB Saunders1988; 1556-1592. Irwig LM, Groeneveld HT, Becklake, MR. Assessing the effect of exposure on lung function loss Margaret R. Becklake, MD - Curriculum Vitae – 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 14 between two occasions: Issues of confounding and measurement error. In. Hemsley MJ, Saunders NA, eds. Clinical epidemiology of chronic obstructive pulmonary disease. New York: Marcel Dekker 1989; 81-98. Bates DV, ed (with the assistance of Becklake, MR. Chan-Yeung M, Fleetham JA, Hogg JC, King M, Ledsome JR, Road JD). Respiratory function in disease. 3rd ed. Philadelphia:WB Saunders1989. Becklake, MR. The epidemiology of asbestosis. In. Liddell D, Miller K, eds. Mineral Fibers and Health. Boca Raton:CRC Press, 1991; 103-119. Becklake, MR. Occupational exposures and chronic airways disease. In. Rom WN, ed. Environmental and Occupational Medicine. 2nd ed. Toronto:Little Brown,1992; 453-63. Becklake, MR. Epidemiology: Prevalence and Determinants. In: Bernstein IL, Chan-Yeung M, Malo JL, Bernstein DI, eds. Asthma in the Workplace. New York: Marcel Dekker, 1993; 29-59. Becklake, MR. Respiratory diseases and tobacco: epidemiologic methodology. In: Hirsch A, Goldberg M, Martin J-P, MassJ R, eds. Prevention of respiratory diseases. New York: Marcel Dekker 1993; 397416. Kauffman F, Becklake, MR. Maladies respiratoires obstructives: un paradigme de la complexité des différences de santé entre hommes et femmes. In. Saurel-Cubizolles MJ, Blondel B, eds. La santé des femmes. Paris: Flammarion Médecine / Sciences, 1996; 209-233. Becklake, MR. Asbestos related disease. In. Stellman JM ed. ILO Encyclopedia of Occupational Health and Safety 4th ed. Part II Health & Work Respiratory System. Geneva: ILO 1997;10:50-10:62. Becklake, MR. Workplace pollution and airway disease: Evidence from community and work force based studies. In. Mohr U, ed. Relationships between respiratory disease and exposure to air pollution. Washington, D.C.: ILSI Press, 1998;133-145 Becklake, M.R. Occupational exposures as a cause of chronic airways disease. In: Rom, W.N.ed Environmental and Occupational Medicine, Philadelphia:Lippincott-Raven, 1998;573-586. Becklake, MR. Malo, J-L. Chan-Yeung M. Epidemiologic Approaches in occupational Asthma. In. Bernstein IL, Chan-Yeung M, Malo JL, Bernstein DI, eds. Asthma in the Workplace. 2nd ed. New York: Marcel Dekker 1999; 27-66 Becklake, MR., Cowie, RL, Pneumoconiosis. In. Murray, JF, Nadel, JA,. Eds Mason, RJ, Boushay, HA Associate Editors. Textbook of Respiratory Medicine, Third Edition. Philidelphia, WB Saunders, 2000, Volume 2; 1811-1851. Kauffman F, Becklake MR. Sex and Gender. Eur Respir Mon 2000:15; 288-304 Becklake MR. Gender differences in airway (physiology) across the human life span. Eur Respir Mon 2003; 25:8:8-25 C) Published Abstracts 1. 2. 3. 4. 5. 6. 7. Kamener R, Becklake MR, Goldman HI, McGregor M. Hyperinflation and lung function following surgery. S Afr Med Sci 1957;22:156 Becklake MR, Varvis CJ, Pengelly LD, Bates DV. Measurement of pulmonary blood flow during exercise, Third International Conference on Medical Electronics “The Respiratory System”, London, July 26, 1960 Becklake MR, Varvis CJ, McGregor M, Bates DV. Measurement of pulmonary blood flow by a foreign gas technique (Can Soc Clin Invest). Can Med Assoc J 1961; 84:562. Macklem PT, Becklake MR. The correlation of mechanical properties of the lung with diffusion, lung mixing and ventilatory tests in chronic lung disease (Can Soc Clin Invest). Can Med Assoc J 1962; 86:225. Massey DG, Becklake MR, Bates DV. Exercise cardiac and lung function in thyrotoxicosis (Can Soc Clin Invest). Can Med Assoc J 1965; 92:360. Becklake MR, Frank H, Dagenais GD, Ostiguy GL, Guzman CA. Effect of age and sex on exercise cardiac output. Fed Proc 1965; 24:466. Andrew GM, Guzman CA, Becklake MR. Exercise cardiac output following physical training. Fed Proc Margaret R. Becklake, MD - Curriculum Vitae – 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. 15 1966; 25:233. Milic Emili J, Holley HS, Becklake MR. Regional ventilation and perfusion of the lung in obesity (CanSoc Clin Invest). Can Med Assoc J 1966; 94:670. Guzman CA, Becklake MR. The effect of acute hypoxia on exercise cardiac output. (Can Soc Clin Invest). Can Med Assoc J 1966; 94:665. Becklake MR. Commentary, Session III: The influence of active conditioning upon subjects with coronary artery disease (Proc of International Symposium on Physical Activity and Cardiovascular Health). Can Med Assoc J 1967; 96:760. Andrew GM, Becklake MR. The effect of training on the lung function of growing children. The Proceedings of the Canadian federation of Biological Society 1967;10:152 Becklake MR, Ouellet U, Poh SC, Douglas FGV, Andrew GMS. Circulatory factors limiting maximum exercise capacity. Fed Proc 1967; 26:721. Ouellet Y, Poh SC, Becklake MR. Cardiac output at maximum O2 uptake. Proceedings of Canadian Society for Clinical Investigation 1967:76-77 Douglas FGV, Andrew GM, Becklake MR. The effect of training on maximal cardiac output. The Proceedings of the Canadian Federation of Biological Society 1967;10:153 Klassen GA, Andrew GM, Zborowska-Sluis DT, Becklake MR. Total and regional blood flow adaptation to training in paddlers. Fed Proc 1968; 27:231. Becklake MR, Douglas FGV, Andrew GM. Effect of different types of athletic training on maximal cardiorespiratory functions. XXIV International Congress of Physiological Sciences, Washington 1968;7:35 Becklake MR, McDonald JC, Fournier-Massey GG, Rossiter CE. Pleural and parenchymal lung changes in asbestos workers and their relative effects on pulmonary function. Am Rev Respir Dis 1969; 99:997. Guzman CA, Caplan R, Becklake MR. Cardiorespiratory response to exercise during pregnancy. Fed Proc 1969; 28:786. Milic Emili J, Ruff F, Couture J, Housley E, Don H, Gardiner A, Becklake MR. Airway closure in relation to pulmonary gas exchange after upper abdominal surgery. Clin Res 1969; 17:670. Craig DB, Wahba WM, Don HF, Couture JG, Becklake MR. The effect of posture on airway closure and gas exchange. Clin Res 1970; 12:742. Becklake MR, Dobell ARC, Fraser G, Graham A, Lemire G, Johnson AL, Palmer WH. Measurement of cardiac function following heart transplantations. Ann Roy Coll Phys Surg Can 1970;52 Seely JE, Guzman CA, Becklake MR. Sex differences in the cardiac and lung function of teenagers. Fed Proc 1971; 30:659. Jodoin G, Gibbs GW, Macklem PT, McDonald JC, Becklake MR. The early effects of asbestos on lung function. Clin Res 1971; 19:512. Wahba WM, Don HF, Craig DB, Becklake MR. Cardio-pulmonary effects of thoracic epidural anaesthesia. Royal College of Physicians and Surgeons of Canada, Regional Meeting, Sherbrooke, Québec, September 24-25, 1971 Seely JE, Guzman CA, Becklake MR. Sex differences in adolescent cardiac function. Clin Res 1971; 19:762. McDonald JC, Becklake MR, Gibbs GW, McDonald AD, Rossiter CE. Epidemiological and clinical studies of asbestos workers in Québec. American Conference of Government and Industrial Hygienists, 34th Annual Conference, San Francisco, May 1972 Becklake MR. Les effets de la pollution atmosphérique chez l’homme dans la région de Montréal. Collège Royal des Médecins et Chirurgiens du Canada, Congrès Régional, Québec, 27-28 octobre 1972 Strobach H, Vaillancourt P, Becklake MR. Evaluation of an on-line computer calculation of N2 closing volume. The Physiologist 1973; 16:3. Sniderman AD, Demedts M, Palmer WH, Utz G, Becklake MR. Lung volumes, including closing volume in acute ischemic left heart failure. Clin Res 1973; 21:1073. Aubry F, Gibbs GW, Swift J, Becklake MR. Respiratory symptoms and lung function in 3 Quebec communities with differing air pollution. Am Rev Respir Dis 1975; 111: 4(pt2):A942. Becklake MR, Fournier-Massey G, Black R. Lung function profiles in Quebec chrysotile asbestos Margaret R. Becklake, MD - Curriculum Vitae – 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. 48. 49. 50. 51. 52. 53. 54. 55. 16 workers. Chest 1975; 69:303. Peress L, Hoag H, White F, Becklake MR. The relationship between closing volume, smoking and asbestos dust exposure. Clin Res 1975; 23:647A. Becklake MR, Jodoin G. A health study of grain handlers in St. Lawrence River Ports. Am Rev Respir Dis 1977; 115: 4pt2):A200. Becklake MR, Hurwitz S, Ross J, Liben A. Lung functions in young adults: evidence for differential onset of aging. Clin Res 1978; 26:876A. Rea H, Becklake MR, Ghezzo H, Allan J, Liben A. The influence of race and sex on the age-related changes of lung function in young adults. Am Rev Respir Dis 1979; 119:4(pt2):A350. Durand P, Rea HH, Fraser W, Becklake MR. Partial flow-volume curves in population studies: a study of four test procedures. Canadian Thoracic Society Annual Scientific Meeting, Toronto 1979 Becklake MR, Gibbs, Arhirii M, Hurwitz S. Respiratory changes in relation to asbestos exposure in manufacturing processes. Am Rev Respir Dis 1980; 121:4(pt2):A223. Leech JA, Ghezzo H, Becklake MR. Lung function from adolescence to early adulthood. Am Rev Respir Dis 1982; 125:4(pt2)A157. Durand P, Ghezzo H, Becklake MR, Martin RR. Prevalence of acute airway response in aluminium potroom workers. Fed Proc 1982; Becklake MR, Toyoto B, Stewart M, Hanson R, Hanley J. Lung geometry as a risk factor in the response to asbestos exposure: a case-referent study in Quebec chrysotile workers. Scan J Work Environ Health 1983; 9:70. Durand P, Martin RR, Becklake MR, Acute respiratory changes in aluminium workers. Scan J Work Environ Health 1983; 9:71. Leech JA, Ernst P, Rogala E, Becklake MR. Cardiorespiratory status in the mild degrees of deformity in idiopathic scoliosis. Am Rev Respir Dis 1983; 127:4(pt2):A225. Rea H, Becklake MR, Ghezzo H. Lung function changes as reflection of tissue aging in young adults. Respiratory Disease Digest 1983 (August):8-9 Ernst P, Thomas D, Becklake MR. Lung function in North American Indian adolescents exposed to particulate fluoride atmospheric pollution. Am Rev Respir Dis 1984; 129:4(pt2):A142. Ernst P, Ghezzo H, Stevens D, Amar D, Berridge L, Becklake MR. Factors influencing short-term prospective measurements of spirometric lung functions in young adults. Am Rev Respir Dis 1984;129:4(pt2): A176 Dales R, Ernst P, Hanley J, Becklake MR. Dealing with measurement error in longitudinal lung function data. Am Rev Respir Dis 1985; 131:4(pt2):A178. Ernst P, Shapiro S, Becklake MR, Determinants of respiratory symptoms in insulators exposed to asbestos and synthetic mineral fibers. Am Rev Respir Dis 1985; 131:4(pt2):A178. Becklake MR, Irwig LM, Kielkowski D, Webster I, de Beer M, Freeman S. Predictors of emphysema in S African goldminers. Am Rev Respir Dis 1986; 133:4(pt2):A264. Zwi A, Becklake MR, Smit AE, Becker PJ, Rendall REG. Relationship between dust exposure and x-ray appearance of pneumoconiosis in two South African foundries. Am Rev Respir Dis 1986; 133:4(pt2):A264. Dales R, Ernst P, Hanley J, Battista R, Becklake MR. The ability of a standardized respiratory symptom questionnaire to predict airway reactivity (AR) as measured objectively. Am Rev Respir Dis 1986; 133:4(pt2):A359. Lalloo UG, Goldsmith CM, Becklake MR. Effect of posture on spirometric indices in healthy subjects. Am Rev Respir Dis 1986; 133:4(pt2):A388. Ernst P, Dales R, Nunes F, Becklake MR, Health selection may be determined by airway reactivity in a dusty environment. Chest 1987; 91:307. Fonn S, Rendall REG, Growneveld H, de Beer M, Poh L, Becklake MR. A respiratory health survey of a Johannesburg grain mill workforce. Chest 1987; 91:299. Masi M, Hanley J, Ernst P, Becklake MR. Environmental exposure to tobacco smoke and lung function in young adults. Am Rev Respir Dis 1987; 135:A341. Bourbeau J, Ernst P, Durand P, Giguere D, Nunes F, Blanchet Y, Nguyen D, Becklake MR, Margaret R. Becklake, MD - Curriculum Vitae – 56. 57. 58. 59. 60. 61. 62. 63. 64. 65. 66. 67. 68. 69. 70. 71. 72. 73. 74. 75. 76. 77. 17 Determinants of respiratory impairment in men at work. Am Rev Respir Dis 1987; 135:A21. Bourbeau J, Ernst P, Chrome J, Nunes F, Armstrong B, Blanchet Y, Becklake MR, Relationship between respiratory impairment and asbestos-related pleural disease in active workers. Am Rev Respir Dis 1988; 137:A92. Bourbeau J, Delfino R, Becklake MR, Ernst P. Tracheal size is a determinant of the bronchoconstrictive response to inhaled methacholine. Am Rev Respir Dis 1988; 137:A231. Fonn S, Groeneveld H, DeBeer M, Becklake MR, Subjective and objective assessment of exposure to grain dust in relation to lung function change over a working week. Progress in occupational epidemiology, Hogstedt C, Reuterwall C, eds., Biomedical Division, Elsevier Science 1988: 271-275. Zwi AB, Reid G, Landau SP, Kielkowski D, Sitas F, Becklake MR, Mesothelioma in South Africa 19761984: estimates of incidence and case characteristics. Am Rev Respir Dis 1989;139:A25 Zwi S, Davies JCA, Becklake MR, Goldman H, Reinach G, Kallenbach J. Respiratory health status of children exposed to environmental air pollution in the Eastern Transvaal highweld. Am Rev Respir Dis 1989; 139:4A28. Becklake MR, Accelerated loss of function due to occupational causes: asbestos and manmade mineral fibers. Joint Meeting SEP-SEPCR, Barbican Centre, London, September 9-14, 1990. Desjardins A, Ernst P, Suissa S, Becklake MR, Turnover rates in a population at risk for laboratory animal allergy. Eur Resp J 1990; 3:112S. N'gan'ga LW, Ernst P, Jaakkola MJ, Gerardi G, Becklake MR, Spirometry test failure: distribution and determinants in an adult working population. Am Rev Respir Dis 1990; 141:A226. Jaakkola MJ, Jaakkola JJK, Ernst P, Becklake MR, Ventilatory lung function in young cigarette smokers; a study of susceptibility. Am Rev Respir Dis 1990; 141:A775. Mokoetle K, De Beer M, Zwi A, Steinberg M, Becklake MR, Determinants of respiratory status in a Johannesburg workforce. Int Epidemiol Assoc, 12th Scientific Meeting, Los Angeles, 1990, 119. White NW, Rooda M, Gerardi G, Nunes F, Menzies R, Becklake MR, Ernst P. Bronchial hyperreactivity assessed by exercise and by methacholine challenge in a study of school children. Am Rev Respir Dis 1991; 143:A273. Jaakkola MS, Ernst P, Jaakkola JJK, Ng'ang'a LW, Becklake MR, Adverse effect of cigarette smoking on evolution of ventilatory lung function in young adults: an eight year longitudinal study. Am Rev Respir Dis 1991; 143:A276. Desjardins A, Suissa S, Becklake MR, Ernst, P. Health selection in cross-sectional studies of occupational asthma due to laboratory animals. Am Rev Respir Dis 1991; 143::A436. Jaakkola MS, Jaakkola JJK, Ernst P, Becklake MR, Development of chronic respiratory symptoms associated with ventilatory impairment in young adulthood. An eight year longitudinal study. Am Rev Respir Dis 1992; 145:A198. Ernst P, Nunes F, Gerardi G, Becklake MR, Distribution and determinants of bronchial hyperresponsiveness to exercise among primary school children. Am Rev Respir Dis 1992; 145:A537. Ng'ang'a LW, Odhiambo JA, Gichega CG, Mohamed N, Menzies R, Macklem PT, Becklake MR, The prevalence of bronchial asthma in primary school children in Nairobi, Kenya. Am Rev Respir Dis 1992; 145:A537. Odhiambo J, Ng'ang'a LW, Gichega CG, Becklake MR, Menzies R, Macklem PT, Omwega MJ. Bronchial hyper-responsiveness to methacholine in Nairobi school children. Am Rev Respir Dis 1992; 145:A537. White NW, Quince JE, Becklake MR, An international comparison of current practices for predicting spirometry in patients of sub-Saharan African ancestry. Am Rev Respir Dis 1992; 145:A538. White NW, Hanley JH, Becklake MR, Spirometric measurements in subjects of sub-Saharan African ancestry. Am Rev Respir Dis 1992; 145:A538. Jaakkola MS, Jaakkola JJK, Ernst P, Becklake MR, Passive smoking and evolution of lung function in young adults. An eight-year longitudinal study. Am Rev Respir Dis 1993; 47:A215. Delfino RJ, Hanley JA, Abenhaim L, Becklake MR, The relationship of urgent hospital admissions for respiratory illness to air pollution levels in Montréal. Am Rev Respir Dis 1993; 147:A638. Demissie K, Ernst P, Hanley J, Nunes F, Becklake MR, Socio-environmental factors and lung function Margaret R. Becklake, MD - Curriculum Vitae – 78. 79. 80. 81. 82. 83. 84. 85. 86. 87. 88. 89. 90. 91. 92. 93. 94. 95. 96. 18 levels among primary school children - a multi level analysis. Third National Conference of the Canadian Society for Epidemiology and Biostatistics. Quebec, June 2-4, 1993. Demissie K, Ernst P, Hanley J, Nunes F, Becklake MR, Adjustment of lung function for height and age among primary school children of different ethnic origins in a Montréal study of environmental exposures. Third National Conference of the Canadian Society for Epidemiology and Biostatistics. Quebec, June 2-4, 1993. Jaakkola MS, Jaakkola JJK, Ernst P, Becklake MR, Passive smoking and evolution of lung function in young adults. An eight-year longitudinal study. Am Rev Respir Dis 1993; 147:A215. Demissie K, Ernst P, Becklake MR, Joseph L. Relationship of prenatal and early postnatal events to lung function and airways responsiveness in school children. Am J Respir Crit Care Med 1994; 149::A910. Escamilla B, Mwawasi G, Comtois P, Becklake MR, Ernst P. The determinants of airborne mold levels in Canadian homes. Am J Respir Crit Care Med 1994; 149:A247. Odhiambo J, Ng'ang'a L, Mungai M, Gichega C, Nyamwaya J, Becklake MR, Macklem PT. Rural and urban respiratory health surveys in Kenya school children: participation rates and prevalence of markers of asthma. Am J Respir Crit Care Med 1994; 148:A385. White NW, Hanley J, Lalloo U, Becklake MR, A review and analysis of variation between spirometric values reported in 29 studies of healthy African adults. Tuberc Lung Dis 1994; 75:128 Demissie K, Ernst P, Joseph L, Locher U, Becklake MR, Socio-economic status and indicators of asthma in children. Am J Respir Crit Care Med 1995; 151:A29. Siersted HC, Ernst P, Becklake MR, Manfreda J, Sears MR. A comparison between two skin prick test methods used within an international asthma prevalence study. Am J Respir Crit Care Med 1995; 151:A565. Odhiambo J, Ng’ang’a L, Mungai M, Gicheha C, Nyamwaya J, Mwawasi G, Becklake MR, Menzies R, Macklem PT. Risk factors for asthma in Kenya school children. Tuberc Lung Dis 1995;76 (suppl 2):6869 Manfreda J, Yeung M, Dimich-Ward H, Sears MR, Siersted HC, Ernst P, Becklake MR, Tate RB, Anthonisen NR. Prevalence of asthma-like symptoms in four Canadian cities. Am J Respir Crit Care Med 1995; 151:A29. Murphy AM, Delfino RJ, Becklake MR, Air pollution and emergency room visits for respiratory illnesses in Montréal: A daily time series. Am J Respir Crit Care Med 1995; 151:A359. Ng’ang’a L, Odhiambo J, Mongai M, Gicheha C, Nyamwaya J, Mwawasi G, Becklake MR, Menzies R, Macklem P. Breast feeding and allergic disease in Kenyan school children. Am J Respir Crit Care Med 1995; 151:A468. Eltayara L, Ploysongsang Y, Volta CA, Becklake MR, Milic-Emili J. Relationship between expiratory flow limitation at rest and degree of dyspnea in COPD patients. Am J Respir Crit Care Med 1995; 151:A548 Poirier C, Chang-Yeung M, Manfreda J, Dimich-Ward H, Sears MR, Siersted H, Becklake MR, Ernst P. Distribution of asthma according to socio-economic status in adult populations. Am J Respir Crit Care Med 1996, 153:A429 Manfreda J, Chan-Yeung M, Dimich-Ward M, Sears MR, Sierstead HC, Becklake MR, Ernst P, Sweet L, VanTil L, Bowie D, Anthonisen NR, Tate RB. Prevalence of asthma in Canada. Am J Respir Crit Care Med 1996 153:A432 Becklake MR, Ernst P, Chan-Yeung M, Manfreda M, Dimich-Ward H, Sears MR, Siersted H. The burden of airway disease attributable to work exposures in Canada. Am J Respir Crit Care Med 1996, 153:4:A433 Chan-Yeung M, Dimich-Ward H, Sears MS, Sierstead HC, Becklake MR, Ernst P, Sweet L, VanTil L, Bowie D, Anthonisen NR, Tate RB, Manfreda J. The effects of smoking on asthma and chronic chest symptoms in Canada. Am J Respir Crit Care Med 1996, 153:A256 Becklake MR, Pollutants, interactions, and vulnerable populations. Tuberc Lung Dis 1996; 77(suppl 2):4S Ng’ang’a L, Odhiambo J, Mungai M, Gicheha C, Becklake MR, Macklem P. Airway responsiveness to methacholine in Kenyan school children. Tuberc Lung Dis 1996; 77(suppl 2):27S-28S Margaret R. Becklake, MD - Curriculum Vitae – 97. 98. 99. 100. 101. 102. 103. 104. 105. 106. 107. 108. 109. 110. 111. 112. 113. 114. 19 Ng’ang’a L, Odhiambo J, Mungai M, Gicheha C, Becklake MR, Macklem P. Airway hyperresponsiveness to exercise in Kenyan children. Tuberc Lung Dis 1996;77(suppl 2):28S Ng’ang’a LW, Becklake MR, Odhiambo JA, Mungai MW, Gicheha CM, Macklem PT. Lung function level among Kenyan school children from rural and urban communities. Am J Respir Crit Care Med 1997, 155:A74 Becklake MR, Ghezzo H, Van Vliet P, Ernst P. Is salivary cotinine a biomarker of lung susceptibility to inhaled pollutants? Am J Respir Crit Care Med 1997,155:A550 Dimich-Ward H, Manfreda J, Sears MR, Siersted HC, Becklake MR, Ernst P, Van Til L, Bowie D, ChanYeung M. Determinants of total IgE levels based on a Canadian prevalence study. Am J Respir Crit Care Med 1997; 155:A80 Manfreda J, Chan-Yeung M, Dimich-Ward H, Sears MR, Siersted HC, Becklake MR, Ernst P, Van Til L, Bowie D, Anthonisen NR, Tate RB. Risk factors for asthma. Am J Respir Crit Care Med 1997; 155:A251 Ghezzo H, Ernst P, Becklake MR, Is salivary cotinine more than a biomarker of exposure to tobacco smoke? Am J Respir Crit Care Med, 1997;155:A550 Becklake MR, Urban environmental risk factors for chronic lung disease Intl J Tuberc Lung Disease 1997;5(suppl 1):8S Mungai M, Odhiambo J, Ng’ang’a L, Gicheha C, Becklake MR, Macklem P. Atopy in rural and urban Kenyan children Intl J Tuberc Lung Disease 1997;5(suppl 1):116S Bowen C, Yaohua D, Songping W, Hui H, Xiaodong Z, Zhang M, Becklake MR. The risk factors of pneumonia death in children under 5 years old in Enshi Country of China Intl J Tuberc Lung Disease 1997; 5(suppl.1):119S Ghezzo H, Becklake MR, Ernst P. Determinants of methacholine bronchial hyper-responsiveness among adolescents. Am J Respir Crit Care Med 1998, 157:A161 Johnson A, Dimich-Ward H, Manfreda J, Sears M, Becklake MR, Ernst P, Bowie D, Sweet L, ChanYeung M. The prevalence of suspected occupational asthma (OA) in a population-based survey. Am J Respir Crit Care Med 1998;157:A882 Ghezzo H, Becklake MR, Ernst P. Determinants of methacholine bronchial responsiveness among adolescents Am J Respir Crit Care Med 1998;157:A161 Ng’ang’a L, Odhiambo JA, Mungai MW, Gicheha CM, Becklake MR, Determinants of urban rural differences for several markers of asthma in Kenyan school children. Eur Respir J 1998;12 (suppl 29):5S Hendrick DJ, Stenton SC, Sandhu PS, Hanley JA, Becklake MR, Statistical Modelling of Exposure to Estimate the Effect of Coal Mine Dust on Lung Function : Risk Before and After the Age of 25 years. Am J Respir Crit Care Med 2000;161:A168 Kassaye T, Becklake MR, Receveur O, Hanley JA, Johns T. Association between lung function level and vitamin A status in children 6-9 years of age in Wukro Wereda, Northern Ethiopia. Eur Respir J 2000;16(suppl 31):177S. Ghezzo RH, Ernst P, Becklake MR. Airway responsiveness in the transition between childhood and adolescence. Eur Respir J 2000;16(suppl 31):471S Hendrick DJ, Stenton SC, Sandhu PS, Hanley JA, Becklake MR. Coal mine dust and COPD: statistical modelling to assess the risk before and after lung matures at the age of 25 years. Eur Respir J 2000;16(suppl 31):27S Hendrick DJ, Hanley JA, Becklake MR, Why are cross sectional and longitudinal estimates of the effect of ageing on lung function commonly discordant? Am J Respir Crit Care Med 2003, 167:A239 D) Published conference or workshop proceedings 1. 2. 3. Becklake, MR. Fournier-Massey G, Mcdonald JC, Siemiatycki J, Rossiter CE. Lung function in relation to radiographic changes in Quebec asbestos workers. In. Shapiro HA, ed. Pneumoconiosis. Proceedings of the International Conference, Johannesburg, 1969, Cape Town, Oxford University Press, 1970; 233-236. Becklake, MR. Lung function. In. Wagner JC, ed. Biological effects of asbestos. International Agency for Research on Cancer, Lyon, 1973; 31-39. McDonald JC, Becklake, MR. Asbestos-related diseases in Canada. In.Hefte zur Unfallkeikunde, Heft Margaret R. Becklake, MD - Curriculum Vitae – 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 20 126, 2 Deutsch-Osterreinchisch-Schweizerische Umfalltagung in Berlin, 1975. Springer-Verlag Berlin Heidelberg, 1976; 521-536, Becklake, MR. Susceptibility to asbestos-related disease. In. Glen NW, ed, Proceedings of Asbestos Symposium, Johannesburg, Africa, National Institute for Metallurgy, Randburg, 1978; 114-116. Becklake, MR. Factors influencing the epidemiology of airways obstruction. In. DeKock MA, Nadel JA, Lewis CM, eds. Mechanisms of airway obstruction in human respiratory disease. Rotterdam, AA Balkema, 1979; 285-92. Becklake, MR. Jodoin G, Utz G, Lefort L, Rose B, Mandl M, Fraser RG. A respiratory health study of grainhandlers in St. Lawrence River Ports. In. Dosman JA, Cotton DJ, eds, Occupational pulmonary disease. New York: Academic Press, 1980; 239-55. Becklake, MR. Grain dust and health: state of the art. In. Dosman JA, Cotton DJ, eds. Occupational pulmonary disease. New York: Academic Press, 1980; 189-99. Becklake, MR. Arhirii M, Gibbs GW, Hurwitz S. Exposure to asbestos and respiratory abnormality: the influence of fibre type and nature of exposure. In. Wagner JC, ed, Biological effects of mineral fibers. Lyon: IARC Scientific Publications No. 30, 1980; 763-9. Becklake, MR. Asbestos miners and millers: morbidity studies. In. Wagner WL, Rom W, Merchant JA, eds., Health issues related to metal and nonmetallic mining. Boston: Butterworth, 1983; 263-275 Becklake, MR. Epidemiology in the workplace: can it answer the clinicians' questions? In. Gee JBL, Morgan WKC, Brooks SM, eds. Occupational lung disease. New York: Raven Press 1984; 109-118. Becklake, MR. Ernst P. Asbestos exposure and airway responses. In. Gee JBL, ed, Contemporary issues in pulmonary disease: Occupational lung disease. Edinburgh: Churchill Livingston, 1984; 25-50. Becklake, MR. Silicosis. In. Dunn CDR, Garnett HM, Jacobs P, eds. Environmental pollution and man. In. Immunology and Hematology Research Foundation Inc. Monograph No. 3, Newburg, 1984; 85-93. Becklake, MR. Occupational and environmental exposures: their relationship to chronic airflow limitation and the role of acute airway dysfunction. In. Dunn CDR, Garnett HM, Jacobs P, eds. Environmental pollution and man. Immunology and Hematology Research Foundation Inc. Monograph No. 3, Newburg, 1984; 111-20. Becklake, MR. Acute respiratory reactions to chemical exposures: focus on oxides of nitrogen. In. Orford RR, Cowell JW, Jamieson GG, Love EJ, eds. Occupational health and the chemical industry, Edmonton: Medichem Calgary, 1984; 207-214. Becklake MR., Rodarte, JR, Kalica AR. Report of Workshop on the Scientific Issues in the Assessment of Respiratory Impairment. U.S. Department of Health and Human Services. National Institutes of Health. NIH Publication No. 87-2924. Becklake, MR. Churg AM, Rosenstock L, Weill H. Mesothelioma update for clinicians. Am Rev Respir Dis 1986; 134:826-7. Becklake MR. The relationship between acute and chronic airway responses to occupational exposures. Metalworking fluids symposium II The industrial metalworking environment: Assessment and control of metal removal fluids, Detroit, September 15-18, 1987 Curr Pulmonol 1988; 9:25-66 Becklake, MR. Population studies in risk assessment: strengths and weaknesses. In. Mohr U, editor-inchief Inhalational Toxicology, New York: Springer-Verlag Inc. 1988; 263-272. Becklake, MR. Lebowitz MD, Kusek JW. NHLBI Workshop Summary. Longitudinal analysis in pulmonary disease epidemiology. Am Rev Respir Dis 1988; 137: 1241-1243. Becklake MR Rodarte, JR, Kalica AR. NHLBI Workshop Summary. Scientific issues in the assessment of respiratory impairment. NHLBI Workshop Summary. Am Rev Respir Dis 1988; 137:1505-1510. Becklake, MR. Evaluation of respiratory hazards in the working environment through environmental, epidemiologic and medical surveys. In. Proceedings of the VIIth International Pneumoconiosis Conference, Pittsburg, Aug. 23-26, 1988. US Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health. DHHS (NIOSH) Publications No. 90-108, Part 1, 16-21. Becklake, MR. Dust and emphysema. In. Sébastien P. Mechanisms in occupational lung diseases. Colloque INSERM, V.203, 1991; 23-34. Becklake, MR. Epidemiological evidence of varying susceptibility to inhaled substances. Margaret R. Becklake, MD - Curriculum Vitae – 24. 25. 26. 27. 28. 29. 30. 31. 32. 21 Pharmacogenetics 1991; 1:98-101. Becklake, MR. Crapo RO, et al. Lung function testing: selection of reference values and interpretative strategies. Am Rev Respir Dis 1991; 144:1202-1218. Becklake, MR. The workrelatedness of airways dysfunction. In. Proceedings of the 9th International Symposium on Epidemiology in Occupational Health held September 23-25, 1992, Cincinnati, Ohio:DHHS (NIOSH) Publication No. 94-112; 1-28. Becklake, MR. Non-malignant asbestos related pleural conditions: clinical significance and associated impairment. In. Gibbs GW, Dunnigan J, Kido M, Higashi T, eds. Health risks from exposure to mineral fibres. An international perspective. North York: Captus University Publications, 1993; 294-301. Becklake MR, Symptoms and pulmonary functions as measures of morbidity. Ann Occup Hyg 1994; 38:569-580. Becklake MR. The workrelatedness of airways dysfunction. US Dept Health and Human Services.Public Health Service,Center for disease Control and prevention National Institute for Occupational Safety and Health DHSS(NIOSH) 1994; 1-29. Beckett W, Abraham J, Becklake MR, Christiani D, Cowie R, Davis G, Jones R, Kreiss K, Parker J, Wagner G. Adverse effects of crystalline silica exposure. (Official Statement of the American Thoracic Association) Am J Respir Crit Care Med 1997; 155:761-765. Becklake MR, Asthma: What is asthma? Is it increasing? And if so, why? . Conference of the New England Governors and Eastern Canadian Premiers, Montréal May 23-24 2002. menv.gouv.qc.ca/air/symposium/index/htm Chan-Yeung M, Malo JL, Tarlo SM, Bernstein L, Gautrin D, Mapp C, Newman-Taylor A, Swanson MC, Perrault G, Vandenplas O, Cartier A, Becklake MR, Jacques L, Blanc PD. Proceedings of the first Jack Pepys Occupational Asthma Symposium. Am J Respir Crit Care Med 2003; 167:450-471. American Thoracic Society Statement: Occupational contribution to the burden of airway disease. Balmes J, Becklake MR, Blanc P, Hennenberger P, Kreiss K, Mapp C, Milton D, Schwartz D, Toren K, Vicgi G Am J Respir Crit Care Med. 2003; 167:787-97 33. E) OTHER 1. Becklake MR. The clinical value of pulmonary mixing studies. MD Thesis, University of Witwatersrand, Johannesburg, South Africa. 1951. 2. Becklake MR. Epidemiologic studies on asbestos related lung diseases in the Quebec chrysotile asbestos mine and mills. Can Dis Wkly Rep 1975; 1-22; 85-88. 3. Becklake MR. L'amiante et la santé humaine: les questions non-résolues. La Vie Médicale au Canada Français 1977; 6:1299-1303. 4. Becklake MR. L'exposition à l'amiante: égale-t-elle maladie? Le Médecin du Québec 1980; 15:83-91. 5. Becklake MR. The pathogenicity of fibres and their morphology (letter) Chest 1981;79:249-250 6. Weill H, Becklake MR. Public responsibility in asbestos-associated diseases. ATS News 1983; 9:5-6. 7. Becklake MR. Asbestos Criteria (letter). Arch Pathol Lab Med 1984; 108:93. 8. Becklake MR. On Dr. Dunnigan's commentary linking chrysotile asbestos with mesothelioma. (letter) Am J Ind Med 1988; 14:239. 9. Rosenberg E, Becklake MR. Single breath carbon monoxide diffusing capacity (letter). Am Rev Respir Dis 1988; 137:1244 10. Becklake MR. Asbestos related pleural disease: distribution and determinants in asbestos exposed workforces and impact on health. In. Asbestos Medicine Seminar, Oct. 25-27, 1989. Chicago, Research Institute, 913c, I1-I16. 11. Becklake MR. Le vieillissement: répercussions fontionnelles. In. "Le désir d'éternité ou la santé à tout prix". Congrès de pneumologie de langue française, Montréal, QC, Canada. 26-29 juin 1991. Paris, France. 3M Santé, 59-64. 12. Becklake MR (Book Review). Katzenellenbogen JM, Joubert G, Abdool Karim SS. Epidemiology: a manual for South Africa. Am J Epidemiol 1998; 148:408-409. Margaret R. Becklake, MD - Curriculum Vitae – 22 Margaret R. Becklake, MD - Curriculum Vitae – SELECTED INVITED LECTURESHIPSHIPS, 1971-2003 Date Occasion/Organisation and Title Oct. 27, 1971 Harvard School of Public Health. Boston, MA, USA. Alice Hamilton Lecturer: Chrysotile-asbestos exposure and the function of the lungs Nov. 1973 Beijing Medical College. McGill University Bethune exchange Professor Beijing, China June 11-14, 1980 23rd Aspen Lung Conference, Denver, CO, USA – Conference Summarizer: The environment and the lung Oct. 10-12, 1982 American College of Chest Physicians World Congress and Annual Meeting, Toronto, ON, Canada: 31st Louis Mark Memorial Lecturer: Occupational Lung Diseases: past record and future trends July 5-6, 1984 College of Medicine of South Africa, Durban, South Africa. Invited speaker: Epidemiology in the 1980's: a chest physician's point-of-view July 30-31, 1984 University of Stellenbosch, Cape, South Africa. Department of Medicine, Ethnor Jansen Visiting Lecturer Oct. 9, 1984 University of Cape Town, South Africa, Department of Medicine, Bernard Pimstone Memorial Lecturer: Epidemiology in the 1980's: a chest physician's point of view. Oct. 16, 1985 Chamber of Mines, Johannesburg, South Africa. A.J. Orenstein Memorial Lecturer: Setting the limits: how do we protect the environment? April 7-10, 1986 University of British Columbia, Canada: Department of Medicine, Respiratory Division. Medical Research Council Visiting Professor: The predictors of emphysema in South African gold miners. Epidemiology in the 1980's: a chest physician's point of view Mar. 23-27, 1987 Inhalational Life Sciences Institute. Inhalational Toxicology, Hanover, West Germany. Invited Speaker: Population studies in risk assessment: strengths and weaknesses. Sept. 1, 1987 European Society of Pneumology, Amsterdam, Holland - Invited Lecturer: Epidemiology of diseases caused by occupational and environmental chemical pollutants Feb. 29, 1988 National Institute for Occupational Safety and Health (NIOSH). Alice Hamilton Award Symposium. Cincinnati, OH, USA - Invited Speaker: Occupational lung disease in the 1980's: an evolving profile June 24, 1988 SEPCR, Athens, Greece - Invited Speaker: Environment and occupations: their role in chronic lung disease VIIth International Conference on the Pneumoconioses (ILO). Pittsburg, PA, USA. Theme speaker: Evaluation of respiratory hazards in the working environment through environmental, epidemiologic and medical surveys 23 Margaret R. Becklake, MD - Curriculum Vitae – Aug. 31, 1989 University of Cape Town, South Africa, Department of Medicine Invited Speaker: Work-related lung diseases: a profile for the 1990's Nov. 5, 1989 Harvard School of Public Health, Boston, MA, USA. The James L. and Peter M. Whittenberger Lecturer: Industrialization: a challenge to the lung Sept. 10, 1990 Joint SEP-SEPCR meeting, London, England: Invited Speaker Symposium on "Accelerated loss of function due to occupational causes" -: Asbestos and man-made mineral fibers Sept. 14, 1990 Association des pneumologues de la province du Québec et la Société de Thoracologie du Québec: Reunion annuelle, Montréal, QC, Canada.: Conférencière Peter Macklem. Les effets néfastes des polluants de l'air sur le systéme respiratoire: l'impact de la sélection naturelle. Dec. 14, 1990 Société de pneumologie de langue française, Paris, France. Symposium sur trouble ventilatoire obstructive chronique. Conférencière invitée: Epidémiologie: facteurs de risques des troubles ventilatoires obstructifs chroniques Apr. 3, 1991 Meakins Christie Laboratory, McGill University, Montréal, Canada. RV Christie Lecturer, 1991 - Spirometric test failure: disease or disinclination July 9, 1991 Epidemiology Society of Southern Africa. 10th Annual Congress University of the Western Cape, South Africa: Keynote address Respiratory disease epidemiology: the lung itself the confounder? April 29, 1992 School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, MD, USA. Anna Baetjer Lecture: Airway responses to urban environments: community and workplace studies May 11, 1992 Issues in Health and Safety in Agriculture, Third International Symposium. Saskatoon, Canada. Invited Speaker: Epidemiology of Respiratory Occupational Disease Sept. 12, 1992 Canadian Thoracic Society, Ottawa, ON, Canada. Christie Memorial Lecture: Why study the epidemiology of airways disease? Sept. 23, 1992 Epidemiology in Occupational Health, 9th Symposium. Cincinatti, OH, USA. Keynote Speaker: The work relatedness of airways dysfunction Feb 8-9. 1996 Institute of Occupational Medicine and Environmental Health, Sosnowiec, Poland. Invited Lecturer:Occupational exposures as a cause of airway disease: evidence from community and workforce based studies. Conférencière invitée: l’Association canadienne-française pour l’avancement des sciences (ACFAS), Montréal, QC, Canada. Symposium: Les syndromes asthmatiques: méchanismes, modèles, populations: Facteurs de risque personnel: le rôle du sexe et du genre May 17, 1996 24 Margaret R. Becklake, MD - Curriculum Vitae – Oct 7-8, 1996 National Institute for Occupational Safety and Health (NIOSH) / Association of Occupational and Environmental Clinics: Workshop on particles not otherwise regulated. Pittsburgh, PA, USA Keynote speaker: Airways disease and occupational exposure to nonfibrogenic dusts Nov 5, 1996 McMaster University, Hamilton, ON, Canada. Firestone Chest Clinic and Allergy Unit, Michael T. Newhouse 5th Annual Lecture. Sex and gender: determinants of airway disease? Oct 2, 1997 Invited Speaker: International Union Against Tuberculosis and Lung Disease: Annual Scientific Meeting, Paris. Urbanization and the Lung Oct 9-10, 1997 Invited Participant: The Lancet Conference on The Challenge of Asthma, Tours, France. Environmental Factors. Nov 2, 1998 Invited Speaker, Symposium on Global views of occupational lung disease, International Union Against Tuberculosis and Lung Disease, Bangkok, Thaïland May 6, 1999 Guest Speaker Alice Hamilton Awards for Excellence in Occupational Safety and Health. National Institute for Occupational Safety and Health (NIOSH), Morgantown, WV. Diseases of Life vs Diseases of Work. Feb 17 - Mar 14, 2000 Mary Weston Lecturer, Departments of Medicine and Community Health University of Natal-Durban, South Africa Sept 22, 2000 Invited Speaker: Symposium on Asthma and Atopy in the Tropics (Chair: Prof. Julian Hopkin). New challenges in tropical medicine and Parasitology, Oxford, England Feb 26-27, 2001 Invited Participant: A Fogerty International Centre Conference: Health in Southern Africa: Lessons of the recent past and the way forward, (Chair: Professor T. Robbins), Johannesburg, South Africa May 23-24, 2002 Invited speaker: La Conférence des Gouverneurs de la Nouvelle Angleterre et des Premiers Ministres de l’Est du Canada. Asthma: What is asthma? Is it increasing? And if so, why?Montreal May 17, 2003 Invited Participant: ATS Postgraduate course on the Social Epidemiology of Lung Disease : Social Inequalities in Lung Disease: Historical overview and noted gaps, Seattle WA 25