MLAB 2434 Microbiology Upper & Lower Respiratory Tract Infections Learning Objectives At the end of this unit, the student will be able to: 1. Describe the basic anatomy of the respiratory tract and explain the mechanical defenses of each anatomic site and how alterations to these sites may lead to infectious diseases. 2. Define the importance of normal flora in the respiratory tract and explain how alterations in the normal flora may lead to infectious disease. 3. Name 5 organisms considered to be normal flora of the upper respiratory tract. 4. Discuss the basic pathogenic mechanisms of infectious diseases of the respiratory tract and the virulence factors of the organisms that cause disease. 5. Describe the most common organisms that cause disease in various upper and lower tract infections. 6. Describe the pathogenesis, risk factors and complications associated with respiratory tract infections as well as types of specimens collected for diagnosis. 7. List the risk factors in immunocompromised hosts that predispose to infections and provide examples of respiratory tract diseases in different types of immunocompromised hosts. 8. Describe the principles and methods of proper specimen collection and transport of respiratory specimens. 9. Discuss the importance of visual examination and proper culturing of respiratory samples. 10. Define colonization. 11. Recognize types of emerging infections. 12. Discuss the treatment of otitis media. 13. Predict a possible pathogen from the respiratory tract based on gram stain, biochemical tests and colony morphology. 14. Evaluate and determine sputum acceptability. 15. Describe the clinical picture of SARS. 2/5/16