Appendix 1: search strategies EMBASE search on the 27th of January 2014 Set 1: physician/ or anesthesist/ or cardiologist/ or dermatologist/ or emergency physician/ or endocrinologist/ or female physician/ or general practitioner/ or gerontologist/ or gynecologist/ or hospital physician/ or internist/ or nephrologist/ or neurologist/ or occupational physician/ or orthopedic specialist/ or pathologist/ or pediatrician/ or podiatrist/ or psychiatrist/ or radiologist/ or surgeon/ or urologist/ or (physician* or clinician* or hospitalist* or consultant* or faculty* or doctor* or anesthesiologist* or anaesthesiologist* or gynecologist* or gynaecologist* or surgeon* or pediatrician* or radiologist* or psychiatrist* or gp* or neurologist* or general practitioner*).ti. and (patient or patients).ti,ab. Set 2: personality/ or interpersonal communication/ or communication skill/ or nonverbal communication/ or persuasive communication/ or verbal communication/ or behavior/ or human characteristic/ or (extraversion or neuroticism or "emotional stability" or stability or emotionality or likability or friendliness or "social conformity" or compliance or conformity or dependability or "openness to experience" or vulnerability or agreeableness or conscientiousness or intellect or dutifulness or tendermindedness or "individual characteristics" or "personal characteristics" or "physician characteristics" or "gp characteristics" or "clinician characteristics" or "consultant characteristics" or "faculty characteristics" or "doctor characteristics" or personality).ti,ab. Set 3: good clinical practice/ or patient satisfaction/ or patient safety/ or job performance/ or professional competence/ or clinical competence/ or exp medical error/ or exp treatment outcome/ or exp mortality/ or health care quality/ or clinical effectiveness/ or incident report/ or complication/ or anesthesia complication/ or catheter complication/ or infection complication/ or infectious complication/ or perioperative complication/ or peroperative complication/ or preoperative complication/ or wound complication/ or (guideline adherence or complaint* or error* or mortality or performance or clinical effectiveness or clinical outcome* or patient outcome or quality of health care or treatment outcome or error* iatrogenic disease or patient readmission or length of stay or reoperation or adverse events or patient safety or unintended events or unintended consequences or patient satisfaction or patient compliance or patient centered care).ti,ab. Not publication types: (book or book series or conference abstract or conference paper or "conference review" or editorial or erratum or letter or note or conference proceeding) Number of hits: 5886 MEDLINE on the 14th of January 2013 (("Physicians"[Mesh] OR "Physician-Patient Relations"[MAJR] OR ((physician*[ti] OR clinician* [ti] OR consultant*[ti] OR faculty[ti] OR doctor*[ti] OR hospitalist*[ti] OR anesthesiologist*[ti] OR anaesthesiologist*[ti] OR gynecologist*[ti] OR gynaecologist*[ti] OR surgeon*[ti] OR pediatrician*[ti] OR radiologist*[ti] OR neurologist*[ti] OR psychiatrist[ti] OR GP[ti] OR general practitioner*[ti]) AND (patient[tiab] OR patients[tiab]))) AND (("personality"[Mesh] NOT ("personality development"[Mesh])) OR "human characteristics"[Mesh] OR “communication”[mesh:NoExp] OR behavior[mesh:NoExp] OR nonverbal communication[Mesh:NoExp] OR extraversion[tiab] OR neuroticism[tiab] OR emotional stability[tiab] OR stability[tiab] OR emotionality[tiab] OR likability[tiab] OR friendliness [tiab] OR social conformity [tiab] OR compliance[tiab] OR conformity[tiab] OR dependability[tiab] OR openness to experience[tiab] OR Vulnerability[tiab] OR agreeableness[tiab] OR conscientiousness[tiab] OR intellect[tiab] OR dutifulness[tiab] OR tender-mindedness[tiab] OR "individual characteristics"[tiab] OR "personal characteristics"[tiab] OR "physician characteristics"[tiab] OR “GP characteristics”[tiab] OR “clinician characteristics”[tiab] OR “consultant characteristics”[tiab] OR “faculty characteristics”[tiab] OR “doctor characteristics”[tiab] OR behavior*[tiab] OR behaviour*[tiab] OR "personality"[tiab]) AND ("Outcome Assessment (Health Care)"[MeSH:NoExp] OR patient centered care[mesh] OR "quality of health care"[Mesh:NoExp] OR "patient care"[Mesh:NoExp] OR "Safety/standards"[Mesh:NoExp] OR patient safety[tiab] OR "complications "[Subheading] OR "Postoperative Complications"[Mesh] OR performance[tiab] OR "Surgical Wound Infection"[Mesh] OR "Patient Readmission"[Mesh] OR "Reoperation"[Mesh] OR "Length of Stay"[Mesh] OR "Iatrogenic Disease"[Mesh] OR mortality[tiab] OR adverse events[tiab] OR "Patient Satisfaction"[MAJR] OR patient outcome*[tiab] OR “clinical effectiveness”[tiab] OR clinical outcome*[tiab] OR patient satisfaction[tiab] OR "professional competence"[Mesh] OR Mortality[Mesh] OR error*[tiab] OR unintended events[tiab] OR unintended consequences[tiab] OR complaint*[tiab] OR guideline adherence[tiab] OR guideline adherence [Mesh])) NOT ("Letter"[Publication Type] OR "Comment"[Publication Type] OR "Editorial"[Publication Type] OR "Guideline"[Publication Type] OR "Case Reports"[Publication Type] OR Practice guideline [publication type] OR autobiography [publication type] OR biography [publication type] OR interview [publication type] OR portraits [publication type]) Number of hits: 5239 PsycINFO search on the 14th of January 2013 Set 1: physicians/ or family physicians/ or general practitioners/ or gynecologists/ or internists/ or neurologists/ or obstetricians/ or pathologists/ or pediatricians/ or psychiatrists/ or surgeons/ or clinicians/ or ((physician* or clinician* or hospitalist* or consultant* or faculty* or doctor* or anesthesiologist* or anaesthesiologist* or gynecologist* or gynaecologist* or surgeon* or pediatrician* or radiologist* or psychiatrist* or gp* or neurologist* or general practitioner*).ti. and (patient or patients).ti,ab.) Set 2: behavior/ or communication/ or interpersonal communication/ or nonverbal communication/ or persuasive communication/ or verbal communication/ or communication skills/ or exp personality traits/ or five factor personality model/ or (extraversion or neuroticism or emotional stability or stability or emotionality or likability or friendliness or social conformity or compliance or conformity or dependability or openness to experience or vulnerability or agreeableness or conscientiousness or intellect or dutifulness or tendermindedness or individual characteristics or personal characteristics or physician characteristics or gp characteristics or clinician characteristics or consultant characteristics or faculty characteristics or doctor characteristics or behavior* or behaviour* or personality).ti,ab. Set 3: treatment guidelines/ or best practices/ or satisfaction/ or client satisfaction/ or consumer satisfaction/ or client participation/ or safety/ or exp job performance/ or professional competence/ or employee efficiency/ or misdiagnosis/ or personnel evaluation/ or occupational success prediction/ or exp treatment outcomes/ or treatment effectiveness evaluation/ or "death and dying"/ or morbidity/ or postsurgical complications/ or treatment duration/ or "quality of care"/ or treatment compliance/ or (guideline adherence or complaint* or error* or mortality or performance or clinical effectiveness or clinical outcome* or patient outcome or quality of health care or patient care or treatment outcome or error* iatrogenic disease or patient readmission or length of stay or reoperation or adverse events or patient safety or unintended events or unintended consequences or patient satisfaction or patient compliance or patient centered care).ti,ab. Number of hits: 1924 Appendix 2: References of studies that related health care providers’ personality or interpersonal behavior to the quality of their provided patient care (studies that included physicians in their sample accompanied with other health care professionals such as residents, students, nurses and physician assistants) Allen AS, Orav EJ, Lee TH, Sequist TD. Clinician personality and the evaluation of higher-risk patient symptoms. J Patient Saf 2011;7:122-126. Begley TM, Lee C, Czajka JM. The relationships of Type A behavior and optimism with job performance and blood pressure. Journal of Business and Psychology 2000; 15: 215-227 Bertakis KD, Roter D, Putnam SM. The relationship of physician medical interview style to patient satisfaction. J Fam Pract 1991;32:175-181. Carter WB, Inui TS, Kukull WA, Haigh VH. Outcome-based doctor-patient interaction analysis: II. Identifying effective provider and patient behavior. Med Care 1982;20:550-566. Cecil DW, Killeen I. Control, compliance, and satisfaction in the family practice encounter. Fam Med 1997;29:653-657. Christen RN, Alder J, Bitzer J. Gender differences in physicians' communicative skills and their influence on patient satisfaction in gynaecological outpatient consultations. Soc Sci Med 2008;66:1474-1483. Clayton MF, Latimer S, Dunn TW, Haas L. Assessing patient-centered communication in a family practice setting: how do we measure it, and whose opinion matters? Patient Educ Couns 2011;84:294-302. Cruz M, Roter DL, Cruz RF, Wieland M, Larson S, Cooper LA, et al. Appointment length, psychiatrists' communication behaviors, and medication management appointment adherence. Psychiatric Services 2013;9:886-92. Davis MS. Variation in patients' compliance with doctors' orders: Medical practice and doctor-patient interaction. Psychiatry in Medicine 1971; 2; 31-54 Dyche L, Swiderski D. The effect of physician solicitation approaches on ability to identify patient concerns. J Gen Intern Med 2005; 20: 267-270. Fossli JB, Dahl FA, Safran DG et al. The ability of a behaviour-specific patient questionnaire to identify poorly performing doctors. BMJ Qual Saf 2011;20:885-893. Gordon GH, Joos SK, Byrne J. Physician expressions of uncertainty during patient encounters. Patient Educ Couns 2000;40:59-65. Graugaard PK, Holgersen K, Finset A. Communicating with alexithymic and non-alexithymic patients: an experimental study of the effect of psychosocial communication and empathy on patient satisfaction. Psychother Psychosom 2004;73:92-100. Hall JA, Irish JT, Roter DL, Ehrlich CM, Miller LH. Satisfaction, gender, and communication in medical visits. Med Care 1994;32:1216-1231. Haskard KB, Williams SL, DiMatteo MR, Rosenthal R, White MK, Goldstein MG. Physician and patient communication training in primary care: effects on participation and satisfaction. Health Psychol 2008;27:513-522. Joos SK, Hickam DH, Gordon GH, Baker LH. Effects of a physician communication intervention on patient care outcomes. J Gen Intern Med 1996;11:147-155. Kinsman H, Roter D, Berkenblit G et al. "We'll do this together": the role of the first person plural in fostering partnership in patient-physician relationships. J Gen Intern Med 2010;25:186-193. Korsch BM, Gozzi EK, Francis V. Gaps in doctor-patient communication. 1. Doctor-patient interaction and patient satisfaction. Pediatrics 1968;42:855-871. Krupat E, Frankel R, Stein T, Irish J. The Four Habits Coding Scheme: validation of an instrument to assess clinicians' communication behavior. Patient Educ Couns 2006;62:38-45. Lobb EA, Butow PN, Barratt A et al. Communication and information-giving in high-risk breast cancer consultations: influence on patient outcomes. Br J Cancer 2004;90:321-327. Pearson SD, Goldman L, Orav EJ et al. Triage decisions for emergency department patients with chest pain: do physicians' risk attitudes make the difference? J Gen Intern Med 1995;10:557-564. Putnam SM, Stiles WB, Jacob MC, James SA. Patient exposition and physician explanation in initial medical interviews and outcomes of clinic visits. Med Care 1985;23:74-83. Robbins JM, Kirmayer LJ, Cathebras P, Yaffe MJ, Dworkind M. Physician characteristics and the recognition of depression and anxiety in primary care. Med Care 1994;32:795-812. Roter DL, Hall JA, Kern DE, Barker LR, Cole KA, Roca RP. Improving physicians' interviewing skills and reducing patients' emotional distress. A randomized clinical trial. Arch Intern Med 1995;155:1877-1884. Roter DL, Stewart M, Putnam SM, Lipkin M, Jr., Stiles W, Inui TS. Communication patterns of primary care physicians. JAMA 1997;277:350-356. Rowland-Morin PA, Carroll JG. Verbal communication skills and patient satisfaction. A study of doctor-patient interviews. Eval Health Prof 1990;13:168-185. Sandhu H, Dale J, Stallard N, Crouch R, Glucksman E. Emergency nurse practitioners and doctors consulting with patients in an emergency department: a comparison of communication skills and satisfaction. Emerg Med J 2009;26:400-404. Shaw WS, Pransky G, Roter DL, Winters T, Tveito TH, Larson SM. The effects of patient-provider communication on 3-month recovery from acute low back pain. J Am Board Fam Med 2011;24:16-25. Sleath B, Carpenter DM, Slota C et al. Communication during pediatric asthma visits and self-reported asthma medication adherence. Pediatrics 2012;130:627-633. Smets EM, Hillen MA, Douma KF, Stalpers LJ, Koning CC, de Haes HC. Does being informed and feeling informed affect patients' trust in their radiation oncologist? Patient Educ Couns 2013;90:330-337. Smith CK, Polis E, Hadac RR. Characteristics of the initial medical interview associated with patient satisfaction and understanding. J Fam Pract 1981;12:283-288. Stapleton RD, Engelberg RA, Wenrich MD, Goss CH, Curtis JR. Clinician statements and family satisfaction with family conferences in the intensive care unit. Crit Care Med 2006;34:1679-1685. Stiles WB, Putnam SM, Wolf MH, James SA. Interaction exchange structure and patient satisfaction with medical interviews. Med Care 1979;17:667-681. Street RL, Jr., Richardson MN, Cox V, Suarez-Almazor ME. (Mis)understanding in patient-health care provider communication about total knee replacement. Arthritis Rheum 2009;61:100-107. Wissow L, Gadomski A, Roter D, Larson S, Lewis B, Brown J. Aspects of mental health communication skills training that predict parent and child outcomes in pediatric primary care. Patient Educ Couns 2011;82:226-232. Zandbelt LC, Smets EMA, Oort FJ, Godfried MH, de Haes HCJM. Medical specialists' patient-centered communication and patient-reported outcomes. Med Care 2007;45:330-339. Appendix 3: Overall study characteristics Characteristic Studies, n (%) Publication year <1989 9 1990-1999 21 2000-2006 19 ≥2007 39 Location United States 46 Netherlands* 13 United Kingdom 8 Australia # 6 Canada 5 Norway 2 Spain 2 Belgium 2 Sweden 1 Switzerland 1 France 1 Poland 1 Specialty Primary Care 46 Oncology 15 Other internal specialties 7 Pediatrics 6 Multiple specialties 5 Surgical specialties 4 Psychiatry 1 Anesthesiology 1 Obstetrics 1 unspecified 2 *= one study also included Belgium, #= one study also included New Zealand Appendix 4: Overall quality of included studies Quality check Number of studies Study Design Single group cross-sectional 48 Single group pre and post-test 28 Non-randomized, two group 2 Randomized controlled experiment 10 Institutions Single institution 25 Two institutions 4 More than two institutions 59 Response rate not reported 33 <50% 13 50-74% 16 75-100% 26 Validity of internal structure reported Not reported 17 Reported 71 Highest outcomes level Patient perceptions 37 Physician behaviors 15 Patient behaviors 21 Patient outcomes 15 adjustment for possible confounders Not adjusted (univariate analysis only) 21 Not adjusted (multivariate analysis) 5 Multivariate adjusted 52 Randomized by study design 10