Curriculum Vitae Part I: General Information DATE PREPARED: 2/3/2000 Name: Karen Klahr Miller Office Address: Neuroendocrine Unit, Bulfinch 457B, Massachusetts General Hospital Place of Birth: Baltimore, MD Education: 1982 B.A. 1987 B.S. 1992 M.D. Yale College Columbia University School of Journalism Johns Hopkins University School of Medicine Postdoctoral Training: Internships and Residencies: 1992-1993 1993-1994 1994-1995 Intern in Medicine, Brigham and Women’s Hospital Junior Resident in Medicine, Brigham and Women’s Hospital Senior Resident in Medicine, Brigham and Women’s Hospital Clinical and Research Fellowships: 1995-1996 1996-1998 Clinical Fellow, Endocrine Unit, Massachusetts General Hospital Research Fellow, Neuroendocrine Unit, Massachusetts General Hospital Licensure and Certification: 1995 1995 1998 American Board of Internal Medicine Certificate Massachusetts License Registration Endocrinology and Metabolism Certification Academic Appointments: 1995-1998 1998- Postdoctoral Research Fellow in Medicine, Harvard Medical School Instructor in Medicine, Harvard Medical School Hospital or Affiliated Institution Appointments: 1995-1996 Essential Clinical Fellow, Department of Medicine, Massachusetts General Hospital Karen K. Miller, M.D. 1996-1998 1998-1999 2000- Research Fellow, Department of Medicine, Massachusetts General Hospital Clinical Assistant, Department of Medicine, Massachusetts General Hospital Assistant in Medicine, Department of Medicine, Massachusetts General Hospital Professional Societies: 1992199519971997- American College of Physicians American Association of Clinical Endocrinologists The Endocrine Society Women in Endocrinology 2 Karen K. Miller, M.D. Professional Societies (Cont’d): 1998- Pituitary Society Awards and Honors: 1982 1982 1982 1982 1992 1997 1998 1998 1998 1999 1999-2001 Summa Cum Laude, Yale College Phi Beta Kappa, Yale College Honors in the Philosophy Major, Yale College Graduation with Honors, Columbia University School of Journalism Alpha Omega Alpha, Johns Hopkins University School of Medicine Recipient, National Research Service Award, National Institutes of Health Recipient, Clinical Research Scholar Award, National Institutes of Health Recipient, Janet McArthur Award, Women in Endocrinology Recipient, Boston Obesity Nutrition Research Center Pilot Research Award Recipient, Clinical Associate Physician Award, National Institutes of Health Claflin Distinguished Scholar Report of Teaching Local contributions: a. Courses Massachusetts General Hospital 1997- Lecturer, Endocrinology Lecture, Institute of Health Professions. 1998- Lecturer, Neuroendocrine Clinical Conferences, Neuroendocrine Unit, MGH Harvard Medical School 1996- Section Leader, Introduction to Clinical Medicine b. Invited presentations: Massachusetts General Hospital 1995 Endocrine Grand Rounds “Supra-sellar Germinomas” 1995 Thyroid/Neuroendocrine Conference “Thyroid Disease and Reproductive Function” 1996 Endocrine Grand Rounds 3 Karen K. Miller, M.D. “Lymphocytic Hypophysitis” 1996 Reproductive Endocrine Conference “Hypothalamic Amenorrhea” 1998 Pediatric Endocrine Unit Conference “Bone Density, Body Composition and Leptin in Women with Hypothalamic Amenorrhea” 4 Karen K. Miller, M.D. b. Invited presentations (Cont’d): Massachusetts General Hospital 1998 Endocrine Research Lectures “Nutrition and Body Composition Determinants of Bone Mass in Premenopausal Women” Brigham and Women’s Hospital 1996 Department of Infectious Diseases Conference and Journal Club “The AIDS Wasting Syndrome in Women” Regional, national or international contributions 1998 Oral presentation of research findings Endocrine Society “Hypoleptinemia in Women with Hypothalamic Amenorrhea” 1998 Oral presentation of research findings Endocrine Society “Increased Severity of Osteopenia in Women with Anorexia Nervosa Compared to Hypothalamic Amenorrhea: The Importance of Undernutrition as an Etiologic Factor in Premenopausal Bone Loss” Bibliography Original Articles 1. Miller KK, Verma A, Snyder SH, Ross CA. Localization of an endoplasmic reticulum calcium ATPase mRNA in rat brain by in situ hybridization. Neuroscience 1991;43:1-9. 2. Grinspoon S, Corcoran C, Miller K, Biller B, Askari H, Wang E, Hubbard J, Anderson E, Basgoz N, Heller H, Klibanski A. Body composition and endocrine function in women AIDS wasting. J Clin Endocrinol Metab. 1997;82:1332-1337. with 3. Miller, KK, Parulekar, MS, Schoenfeld, E, Anderson E, Hubbard, J, Klibanski A, Grinspoon S. Decreased leptin levels in normal weight women with hypothalamic amenorrhea: The effects of body composition and nutritional intake. J Clin Endocrinol Metab. 1998;83(7):2309-2312. 4. Miller KK, Corcoran C, Armstrong, C, Caramelli, K, Anderson EJ, Cotton D, Basgoz N, Hischhorn L, Tuomala R, Schoenfeld D, Doherty C, Mazer N, Grinspoon S. Short-term 5 Karen K. Miller, M.D. transdermal testosterone administration in women with AIDS wasting. J Clin Endocrinol Metab. 1998;83(8):2717-2725. 5. Miller KK, Daly PA, Sentochnik D, Doweiko J, Samore M, Basgoz NO, Grinspoon SK. Pseudo-Cushing’s syndrome in HIV-infected patients. Clin Infect Dis. 1998;27:68-72. 6. Grinspoon S, Corcoran C, Miller K, Wang E, Hubbard J, Schoenfeld D, Anderson E, Basgoz N, Klibanski A. Determinants of increased energy expenditure in HIV-infected women. Am J Clin Nutr. 1998; 68:720-725. 6 Karen K. Miller, M.D. Original Articles (Cont’d) 7. Grinspoon S, Miller K, Coyle C, Krempin J, Armstrong C, Pitts S, Herzog D, Klibanski A. Severity of osteopenia in estrogen-deficient women with anorexia nervosa and hypothalamic amenorrhea. J Endocrinol Metab. 1999;84(6):2049-2055. 8. Hadigan C, Miller K, Corcoran C, Anderson E, Bascoz N, Grinspoon S. Fasting hyperinsulinemia and changes in regional body composition in human immunodeficiency virus-infected women. J Clin Endocrinol Metab. 1999;84(6):1932-1937. 9. Miller KK, Grinspoon S, Klibanski A. Cardiovascular risk markers in hypothalamic amenorrhea. Clin Endo. (In press). 10. Hadigan C, Anderson E, Miller K, Hubbard J, Herzog D, Klibanski A, Grinspoon S. Assessment of macronutrient and micronutrient intake in women with anorexia nervosa. International Journal of Eating Disorders (In press). Reviews 1. Miller K, Klibanski A. Amenorrhea and osteoporosis. In Kleerekoper M, Siris E, McClung M, editors. The bone and mineral manual: a practical guide. San Diego, CA: Academic Press. 1999. 2. Miller KK, Klibanski A. Amenorrheic bone loss. J Clin Endocrinol Metab. 1999; 84(6). Abstracts 1. Grinspoon S, Miller K, Coyle C, Krempin J, Herzog D, Klibanski A. Increased severity of osteopenia in women with anorexia nervosa compared to hypothalamic amenorrhea . Endocrine Society, 1998. 2. Miller K, Corcoran C, Caramelli K, Daugherty C, Mazer N, Grinspoon S. Transdermal testosterone administration in women with AIDS wasting: a pilot study. Endocrine Society, 1998. 3. Miller K, Parulekar M, Schoenfeld E, Anderson E, Hubbard J, Klibanski A, Grinspoon S. Hypoleptinemia in women with hypothalamic amenorrhea. Endocrine Society, 1998. 4. Grinspoon S, Corcoran C, Miller K, Wang E, Hubbard J, Schoenfeld D, Anderson E, Basgoz N, Klibanski A. Determinants of increased energy expenditure in HIV-infected women . Twelfth World AIDS Conference, 1998. 5. Miller KK, Grinspoon S, Klibanski A. Hypothalamic amenorrhea as an age-independent model of the effects of estrogen-deficiency of cardiac risk factors. Endocrine Society, 1999. 7 Karen K. Miller, M.D. 6. Miller KK, Sesmilo G, Schiller A, Burton S, Klibanski A. Androgen Deficiency in Women with Hypopituitarism. The Endocrine Society 82nd Annual Meeting, 2000. 8