1 Online appendix Questionnaire on perioperative nutrition Please reply to every question by choosing the most appropriate answer(s). One or more answers may be given per question if adequate. 1. Where do you work? University hospital Non University hospital O O >400/year <400/year O O 2. How many GI surgical interventions are performed in your facility? Screening 3. Does your facility conduct a nutritional screening? 4. Who is responsible for the nutritional screening? 5. When is the screening performed? 6. How is the screening performed? Always Sometimes Rarely Never O O O O Surgeon O Anaesthesiologist O Responsible nursing staff O Nutritionist O Preoperatively in outpatient clinic O Preoperatively on admission O Postoperatively O In the ICU O Clinical parameters (weight loss, BMI, etc.) Examples: _____________________________________ Laboratory values (albumine, (prealbumine), etc.) Examples: _____________________________________ O O Biometrical measurements (impedance, subcutaneous fat, etc.) O Examples: _____________________________________ Clinical scores (SGA, NRS, etc.) Examples: _____________________________________ O Nutritional supplementation 7. Immunonutrition contains in your opinion ... Arginine O Glutamine O Non-saturated fatty acids O mRNA O Others:______________________________ 8. Do your patients receive a preoperative nutritional supplementation? 9. Who is receiving the treatment? O Always Sometimes Rarely Never O O O O All patients O All patients before major GI surgery O All patients previously identified by nutritional screening O All patients before oncological GI surgery O Others: _________________________________ O 2 10. Who is conducting the treatment? Surgeon O Responsible nursing staff O Nutritionist O Preoperatively O Postoperatively O Preoperatively und postoperatively O 12. How long is the preoperative treatment 3 days O conducted? 5 days O 7 days O No preoperative treatment in our facility O 13. Which type of nutritional support is used for Protein drinks O preoperative treatment? Immunonutrition O 11. When is the treatment conducted? O Others: ________________________________ 14. How do you control the success of the No control/No preoperative treatment O preoperative treatment? Nutritional diary O Clinical parameters (weight loss, BMI, etc) O Examples: __________________________________ Laboratory values (albumine, (prealbumine), etc) O Examples: __________________________________ Biometrical measurements(impedance, subcutaneous fat, etc) O Examples: __________________________________ Appraisal of current evidence of preoperative nutritional supplementation Yes No O O O O 17. Is there sufficient evidence available for the use of preoperative nutritional supplementation? O O 18. Is there sufficient evidence available in favour of preoperative Immunonutrition? O O 19. Too expensive with regard to the ambiguous absorption of cost O O 20. Logistical efforts O O 21. No sufficient scientific evidence available O O 22. Others: ________________________________________________________________ O O Please express your opinion! 15. Does the use of preoperative nutritional supplementation have a positive impact on the length of stay in the hospital? 16. Does the use of preoperative nutritional supplementation have a positive impact on the perioperative complication rate? Reasons against the use of preoperative Immunonutrition: