Practice Management Guidelines for Diagnosis and Management of Blunt Cardiac Injury March 1997 – December 2011 First Author Sanfa GS Year 2011 Reference Title Serum troponin-I as an indicator of clinically significant myocardial injury in paediatric trauma patients. Injury. 2011 Nov 25. Class 3 Conclusions Observational study. Prevalence of elevated TnI in pediatric trauma patients is 27%. While this correlates with overall severity of injury, it does not correlate with myocardial injury. Co SJ 2011 Role of imaging in penetrating and blunt traumatic injury to the heart. Radiographics. 2011 JulAug;31(4):E101-105. Myocardial infarction after blunt chest trauma: usefulness of cardiac ECG-gated CT and MRI for positive and aetiologic diagnosis. Emerg Radiol. 2011 Jun;18(3):271-4. CT imaging of blunt chest trauma. Insights Imaging. 2011 Jun;2(3):281-295. 3 Review. Multidetector CT has increased the diagnosis of cardiac injury, and is the most important diagnostic tool in initial evaluation of patients who have sustained blunt cardiac injury. Case reports. ECG gating is able to identify specific coronary lesions to differentiate acute myocardial infarction from traumatic cardiac injury. Malbranque G 2011 Oikonomou A 2011 Sheikh M 2009 Accuracy of 64-multidetector-row computed tomotgraphy in the diagnosis of coronary artery disease. Med Princ Pract 2009;18(4):323-328. 3 Leibecke T 2008 Posttraumatic and postoperative cardiac luxation: computed tomography finding in nine patients. J Trauma 2008;64(3):721-726. 3 Scaglione M 2008 Multi-detector row computed tomography and blunt chest trauma. Eur J Radiol 65:377-388. 3 Southam S 2006 3 Mirvis SE 2005 Ismailov RM 2005 Contrast-enhance cardiac MRI in blunt chest trauma: differentiating cardiac contusion from acute peritraumatic myocardial infarction. J Thorac Imaging 2006;21(2):176-178. Imaging of acute thoracic injury: the advent of MDCT screening. Semin Ultrasound CT MR 2005;26(5):305-331. Blunt cardiac injury associated with cardiac valve 3 3 3 3 Review. The advent of MDCT has decreased time required to scan trauma patients and allowed for improved detection of injuries. It is now the gold standard for diagnosis of many injuries, such as aortic injury. When mediastinal hematoma is excluded as an indirect sign of aortic injury, sensitivity and specificity are 98% and 100%. Prospective study comparing MDCT to coronary angiography. Patients with suspected CAD who were scheduled to have cardiac catheterization first underwent MDCT, with blinding of the radiographers and those performing the catheterizations to the respective results. Sensitivity and specificity were high for CTA of the main vessels. Sensitivity was lower for segmental arteries, but specificity was still good, making it a useful tool for ruling out significant disease. Case series. Traumatic cardiac luxation represents a serious complication of pericardial rupture. CT is useful in identifying this early so the intervention can be instituted in a timely fashion and delay morbidity and mortality. Review. MDCT is highly sensitive for blunt chest trauma and should be used as an important adjunct in the evaluation of patients who have sustained blunt chest trauma. Case report. Myocardial contusion and myocardial infarction have distinct findings on cardiac MRI that allow for differentiation between the two, which aids in therapeutic decision making. Review. The increased sensitivity of MDCT aids in not only the diagnosis, but the characterization of blunt thoracic injury. Routine use is practical and efficient. A retrospective review of hospital discharge database. There was an Practice Management Guidelines for Diagnosis and Management of Blunt Cardiac Injury March 1997 – December 2011 insufficiency: trauma links to chronic disease? Injury. 2005;36:1022-8. Rajan GP 2004 Cardiac troponin I as a predictor of arrhythmia and ventricular dysfunction in trauma patients with myocardial contusion. J Trauma. 2004;57:801-8 Incidence and significance of cardiac troponin I release in severe trauma patients. Anesthesiology. 2004;101:1262-8. 2 Edouard AR 2004 Lancey RA 2003 Correlation of clinical characteristics and outcomes with injury scoring in blunt cardiac trauma. J Trauma. 2003;54:509-15. Normal electrocardiography and serum troponin I levels preclude the presence of clinically significant blunt cardiac injury. J Trauma. 2003;54:45-51 2/3 Velmahos GC 2003 Lindstaedt M 2002 Acute and long-term clinical significance of myocardial contusion following blunt thoracic trauma: results of a prospective study. J Trauma. 2002;52:479-85. 2 Athanassiadi K 2002 Sternal fractures: retrospective analysis of 100 cases. World J Surg. 2002;26:1243-6. 2 Collins JN 2001 The usefulness of serum troponin levels in evaluating cardiac injury. Am Surg. 2001;67:821-6. 2 2 2 increased association of Limited conclusions based the nature of the database (discharge) used, there are associations but no ability to determine cause and effect Prospective observational study of 187 multiply injured patients with blunt chest trauma and suspected BCI. Troponin I <1.05 ruled out BCI. Authors recommended that for cTnI >1.05g/L should undergo further cardiac evaluation and monitoring. Observational study. Elevated troponin had no prognostic value for stable patients, but authors recommend that positive values need further work up Myocardial contusion was diagnosed by ECG criteria. Significant elevation of cTnI >2.0 g/L Values for cTnI in predicting BCI: Sensitivity: 63% Specificity: 98% PPV: 40% NPV: 98% Retrospective review of 47 patients with dx BCI. Higher OIS grades seem to correlate with severity of injury and survival. Prospective observational study (n=333) pts with chest trauma followed with cTnI, serial ECGs, and selective use of echo. The combination of normal ECG and enzymes at 8h post trauma rules out significant injury (NPV=100%). If both enzymes and ECG are abnormal, PPV of 34% of significant blunt cardiac injury. 5/67 patients with normal ECG had positive troponin and had “significant BCI” (significant defined as hypotension, arrhythmia, decreased cardiac index, treatment required). This study suggests that a normal ECG by itself, cannot rule out significant BCI. Prospective observational study (n=118) with 3 and 12 month follow up. BCI dx by ECG changes and CK-MB>7%. Patients who are hemodynamically stable on admission do not deteriorate. Routine work up for patients with thoracic trauma is not necessary for patients to rule in or out BCI. Retrospective study of 100 patients with sternal fracture, one patient had “cardiac contusion”. Routine screening with echo not warranted for sternal fractures Prospective (n=66) Positive troponin values have a low PPV. Normal ECG rules out BCI. Abnormal ECG with normal troponin rules out BCI. Patients with abnormal ECG and troponin should be admitted with Practice Management Guidelines for Diagnosis and Management of Blunt Cardiac Injury March 1997 – December 2011 Wiener Y 2001 Echocardiogram in sternal fracture. Am J Emerg Med. 2001;19:403-5. 3 Walsh P 2001 2 Vignon P 2001 Rashid MA 2001 Salim A 2001 Nagy KK 2001 Swan KG Jr 2001 Use of V4R in patients who sustain blunt chest trauma. J Trauma. 2001;51:60-3. Comparison of multiplane transesophageal echocardiography and contrast-enhanced helical CT in the diagnosis of blunt traumatic cardiovascular injuries. Anesthesiology. 2001;94:615-22 Cardiovascular injuries associated with sternal fractures. Eur J Surg. 2001;167:243-8. Clinically significant blunt cardiac trauma: role of serum troponin levels combined with electrocardiographic findings. J Trauma. 2001;50:237-43. Determining which patients require evaluation for blunt cardiac injury following blunt chest trauma. World J Surg. 2001 Jan;25(1):108-11. Decelerational thoracic injury. J Trauma. 2001;51:970-4 Sadaba JR 2000 Bertinchant JP 2000 Rashid MA 2000 Tanaka H 1999 1/2 telemetry. Incidence of BCI with sternal fracture was 8% (4/50). None of these patients required intervention for their BCI. Patients with isolated sternal fracture do not require echocardiogram. 45 blunt chest trauma pts vs 40 unmatched control subjects. Left sided ECGs were distinguishable from between chest trauma pts and controls. Right sided ECG does not add to the diagnosis of BCI Prospective, observational study (n=110) TEE superior to CT in diagnosis of cardiac injury (eg, valve damage). CT does not rule out BCI 3 Retrospective chart review (n=418, 29 sternal fractures). Sternal fracture is not a marker for BCI 2 Prospective, non-randomized (n=115). NPV of normal ECG and troponin was 100% in combination. Normal ECG did not rule out BCI 2 Patients with an abnormal ECG need monitoring. Patients with normal ECG, hemodynamics, and cardiac enzymes do not need further intervention. Single institution retrospective review of decelerational thoracic injuries. Of the 171 patients with ICD-9 codes for myocardial contusion, only 38 (22%) had that diagnosis supported on review of the medical record. Case review (n=37) pts with sternal fracture. Sternal fracture is not a marker for BCI. 3 Management of isolated sternal fractures: determining the risk of blunt cardiac injury. Ann R Coll Surg Engl. 2000;82:162-6. Evaluation of incidence, clinical significance, and prognostic value of circulating cardiac troponin I and T elevation in hemodynamically stable patients with suspected myocardial contusion after blunt chest trauma. J Trauma. 2000;48:924-31. Cardiac injuries: a ten-year experience. Eur J Surg. 2000;166:18-21. 2 Pericardial tamponade type injury: a 17-year study in an urban trauma center in Japan. 3 2 Prospectively collected data (n=94, 26 with “myocardial contusion” diagnosed by ECG, echo). There was no diff in CK, CK-MB between those with BCI and those without. The low sensitivity (23%, 12%) and low predictive values of troponin-I and troponin-T do not provide an improved method of dx of BCI in hemodynamically stable patient. 2 Retrospective case review of 11 cardiac injury pts 4 with blunt mechanism. BCI diagnosis consumes considerable resources, but the disease often has little clinical relevance. Retrospective study of pericardial tamponade. Of patients with tamponade from blunt cause (n=12), five had “myocardial contusion”. Practice Management Guidelines for Diagnosis and Management of Blunt Cardiac Injury March 1997 – December 2011 Velmahos GC 1999 Swaanenburg JC 1998 Garcia-Fernandez MA 1998 Chiu WC 1997 Fulda GJ 1997 Surg Today. 1999;29:1017-23 The "seat belt mark" sign: a call for increased vigilance among physicians treating victims of motor vehicle accidents. Am Surg. 1999;65:181-5. Troponin I, troponin T, CKMB-activity and CKMBmass as markers for the detection of myocardial contusion in patients who experienced blunt trauma. Clin Chim Acta. 1998;272:171-81. Role of transesophageal echocardiography in the assessment of patients with blunt chest trauma: correlation of echocardiographic findings with the electrocardiogram and creatine kinase monoclonal antibody measurements. Am Heart J. 1998;135:476-81. Sternal fractures in blunt chest trauma: a practical algorithm for management. Am J Emerg Med. 1997;15:252-5. An evaluation of serum troponin T and signalaveraged electrocardiography in predicting electrocardiographic abnormalities after blunt chest trauma. J Trauma. 1997;43:304-12. 2 2 2 2 2 Tamponade patients from blunt mechanism had average ISS =54 Retrospective review of pts with seatbelt mark. 7.5% of patients with seatbelt mark had a BCI, if abnormal ECG, got an echo, none of the patients with BCI required intervention or treatment. Review of 89 blunt trauma pts separated by thoracic and non-thoracic trauma. Examined CK, CK-MB, and relative ratios and troponin. CKMB no useful in diagnosis of BCI. While troponin may be helpful in diagnosis of BCI, the optimal timing of measurement needs to be determined. Multicenter, prospective, non-randomized (n=117) CK-MB not useful in diagnosis of BCI. Normal ECG does not rule out BCI. TEE is a valuable tool to identify patients needing surgery. Retrospective study (n=33) of sternal fracture and relationship to BCI. Sternal fracture is not a marker for BCI. Management of sternal fracture should be directed at management of associated injuries. Prospective study (n=71). Signal averaged ECG is not helpful in the diagnosis of BCI. Initial ECG is the best overall predictor of BCI. Troponin T may have a role in the evaluation of patients with normal ECG.