Photo: Göran Assner XXXIV Nordic Congress in Clinical Chemistry September 16 – 19, 2014 at Svenska Mässan in Göteborg Final Programme www.nfkk2014.se Nordisk Forening for Klinisk Kemi SKKLF Sveriges klinisk kemiska laboratorieingenjörers förening C: 88 M: 0 Y: 57 K: 36 Contents Welcome............................ 1 Committees......................... 2 Scientific Program, Overview...... 4 Scientific Program, Day by Day.... 7 Posters list. . ....................... 13 Author index. . .................... 18 Guidelines for Speakers.......... 24 Social Program. . .................. 26 Congress Information............ 27 General Information. . ............ 28 Our Exhibitors. . ................... 34 City Map.......................... 36 Dear NCCC Delegates It is a pleasure and a privilege to welcome you to Gothenburg, Sweden, for the XXXIVth Nordic Congress in Clinical Chemistry on September 16 –19, 2014. A major aim of the NCCC 2014 is to gather all professions in the clinical labs in the Nordic countries, to meet, discuss and share knowledge. Another aim is to broaden our perspective with the overall theme of ”Future opportunities in clinical chemistry”. This includes exciting examples of how the laboratory with its expertise among physicians, biomedical scientists, chemists and laboratory engineers can develop further as a diagnostic partner. The meeting will also cover the use of new biomarkers in risk assessment and diagnosis, novel areas of biomarker discovery, including glycoproteomics, tissue-specific inflammation and an interesting example of using biomarker patterns in multivariate analysis. We will also learn about emerging laboratory techniques, including Next Generation Sequencing and single molecule detection. We wish to extend a cordial welcome to Gothenburg to all of you, and we hope that, during this meeting and especially at the spectacular Glitter & Glamour banquet on the 18th of September, you will meet old friends, make new friends and establish important future connections with colleagues throughout the Nordic countries. On behalf of the organizing committee I wish you all VERY WELCOME to Gothenburg! Ola Hammarsten President, XXXIV Nordic Congress in Clinical Chemistry 1 Committees Organising Committee Ola Hammarsten, Chairman of the Scientific Committee for The XXXIVth Nordic Congress in Clinical Chemistry, MD, PhD, Professor, Senior Consultant, Clinical Chemistry, Sahlgrenska University Hospital Birgitta Kallberg, Head of Unit Clinical Chemistry, Sahlgrenska University Hospital/Mölndal Camilla Brantsing, Biomedical Scientist, Section leader at Clinical molecular research, Clinical Chemistry, Sahlgrenska University Hospital Therese Lorentzon Gräbel, Head Secretary, Clinical Chemistry, Sahlgrenska University Hospital Scientific Committee Ola Hammarsten, Chairman of the ­Scientific Committee for The XXXIVth ­Nordic Congress in Clinical Chemistry, MD, PhD, Professor, Senior Consultant, Clinical Chemistry, Sahlgrenska University Hospital Jorge Asin Cayuela, MD, PhD, Associate Professor, Clinical Chemistry, Sahlgrenska University Hospital Julia Asp, PhD, Associate Professor, Clinical Chemistry, Sahlgrenska University Hospital Anders Elmgren, MD, PhD, Clinical ­Chemistry, Sahlgrenska University Hospital Linda Fogelstrand, MD, PhD, Clinical Chemistry, Sahlgrenska University Hospital 2 Stefan Jacobsson, MD, Senior Consultant Clinical Chemistry, Sahlgrenska University Hospital Anne-Marie Johannesson, POCT ­Coordinator, Biomedical Scientist, Clinical Chemistry, Sahlgrenska University Hospital Helene Johansson, President, The Swedish Institute of Biomedical Laboratory Science, Regional Quality coordinator for haematologi­ cal diagnostics in Västra Götaland, Clinical Chemistry, Sahlgrenska University Hospital Göran Larson, MD, PhD, Professor, Senior Lecturer, Clinical Chemistry, ­Sahlgrenska University Hospital Anders Larsson, MD, PhD, Professor and Consultant, Clinical Chemistry, Akademiska Hospital, Uppsala Lars Palmqvist, MD, PhD, Associate ­Professor, Senior Consultant, Clinical Chemistry, Sahlgrenska University Hospital Anders Lindahl, MD, PhD, Professor, Clinical Chemistry, Sahlgrenska University Hospital Anne Ricksten, PhD, Associate Professor, Clinical Chemistry, Sahlgrenska University Hospital Christian Löwbeer, MD, PhD, Clinical Chemistry, Aleris Medilab Mats Ohlson, PhD, Clinical Chemistry, Sahlgrenska University Hospital, President of The Swedish Association of Clinical ­Biochemists Henrik Zetterberg, MD, PhD Professor of Neurochemistry, Senior Consultant in Clinical Chemistry, Sahlgrenska University Hospital Conference Organisation Conference organisation, registration and abstract management, sponsoring and exhibition. Congress secretariat Delegate service, housing, social programme MCI – Gothenburg Office Mail: confirmation@mci-group.com Phone: + 46 (31) 780 30 30 www.mci-group.com Congress venue The Swedish Exhibition & Congress Centre (Svenska Mässan) Mässans Gata 2, Gothenburg, Sweden 3 Scientific Program Overview Tuesday, September 16 Room: 11:00 Registration 13:20 Opening Ceremony F3 13:30 Afternoon Session: Food, metabolomics and health F3 15:15 Welcome Reception in the exhibition hall Wednesday, September 17 08:00 – 08:45 Breakfast seminar: Beckman Coulter AB F1 09:00 Morning Plenary session: Future biomarkers in acute coronary syndromes F3 09:45 Coffee and exhibition in the exhibition and poster area 10:15 Biomarkers for future risk of cardiovascular disease F1 10:15 Laboratory Point Of Care Testing – current and future ­challenges F2 10:15 Novel laboratory technology – the single ­molecule era F3 12:00 Lunch – Exhibition and lunch seminars 12:30–13:15 Abbott Scandinavia AB F1 12:30–13:15 Siemens Healthcare Diagnostics F2 14:00 Afternoon Plenary session: Surface-based single-liposome sensing for diagnostics and drug screening applications F3 14:45 Coffee and exhibition in the exhibition and poster area 15:15 Novel diagnostic biomarkers in cardiology F1 15:15 The Astrup Prize F2 15:15 Next Generation Sequencing (NGS) in clinical diagnosis F3 16:00 SKKLF Annual Meeting Nordensköld 16:45 SSKF Annual ­Meeting F3 Possibility for companies to arrange a social sponsor a ­ ctivity 4 Thursday, September 18 Room: 08:00 – 08:45 Breakfast seminar: HemoCue F2 08:00 – 08:45 Breakfast seminar: Thermo Fisher Scientific F1 09:00 Morning Plenary session: Vitamin B12 deficiency New trends in biomarkers and diagnostic ­strategies F3 09:45 Coffee and exhibition in the exhibition and poster area 10:15 Rare disorders of erythrocytes. The dysregulation of iron and ferritin h ­ omeostasis F1 10:15 Biomarkers in diagnosis of neurodegenerative diseases F2 10:15 The future clinical laboratory as a diagnostic partner F3 12:00 Lunch – Exhibition and lunch seminars 12:30–13:15 Roche Diagnostics AB F1 12:30–13:15 Sysmex Sverige F2 14:00 Afternoon Plenary session: Blood based biomarkers for ­Alzheimer’s disease – from case control to endophenotype discovery and from small to large, potentially huge, replication F3 14:45 Coffee and exhibition in the exhibition and poster area 15:15 Laboratory diagnostics of myeloproliferative neoplasms F1 15:15 The Eldjarn Prize F2 15:15 Organization of the future clinical laboratory F3 16:45 SFKK Annual Meeting F1 19:30 Banquet “Glitter and Glamoure” in Estrad Restaurant Friday, September 19 09:00 Morning Plenary session: Application of massively parallel sequencing (MPS) for clinical analyses: challenges and opportunities F3 09:45 Coffee and exhibition in the exhibition and poster area 10:15 Clinical laboratory education today and tomorrow F1 10:15 Future use of cancer biomarkers F2 10:15 Biomarkers of kidney disease F3 12:00 Poster Prize winning ceremony and Closing Remarks F3 5 ARCHITECT STAT HIGH SENSITIVE TROPONIN-I ASSAY Redefining Precision to Increase Confidence in Decision Making for Chest Pain in the Acute Setting Hear more at our Lunch Symposium Wednesday, September 17th, 12.30-13.15, Room F1 or come to the Abbott Booth 6 www.abbott.com ADD-00003721 Scientific Program, day by day Tuesday, September 16 07:00 Exhibition building up and moving in 07:00–10:00 11:00 Registration 13:20 – 13:30 Opening Ceremony Room: F3 Opening of the XXXI V Nordic Congress in Clinical Chemistry by the President Ola Hammarsten 13:30 – 15:00 Afternoon session: Food, metabolomics and health Room: F3 Metabolites and antioxidants from dietary sources or produced endogenously are becoming an important field of study to find new biomarkers for disease. This session will discuss recent developments in the study of the human metabolome, inflammation and the role of antioxidants in health and disease Chair: Ola Hammarsten 13:30 –14:00 Clinical Metabolomics: the next stage of clinical biochemistry? (101) Jan Borén, Sweden 14:00 –14:30 Can we tell infection from tissue damage as a cause of inflammation? A strategy using clinical chemistry and patten recognition methods (102) Agnes Wold, Sweden 14:30–15:00 Antioxidants – the dark side (103) Per Lindahl, Sweden 15:15 Welcome Reception in the exhibition hall The reception is hosted by the City of Göteborg and the Region of Västra Götaland. 7 Wednesday, September 17 08:00 – 08:45 Breakfast seminar: Beckman Coulter AB Room: F1 Beckman Coulter’s Innovative Approach to Automating Clinical Molecular Diagnostics Speaker: Brendan McKeown, PhD, Senior Molecular Applications Specialist, UK 09:00 Morning Plenary session Room: F3 Chair: Ola Hammarsten Future biomarkers in acute coronary syndromes (201) Bertil Lindahl, Sweden 09:45 Coffee and exhibition in the exhibition and poster area 10:15 Parallel Sessions Room F1: Biomarkers for future risk of cardiovascular disease Our ability to use biomarkers to predict the development of cardiovascular disease in a healthy person, as a foundation for primary prevention, is currently less than perfect. This session will discuss approaches to finding new biomarkers that may be used for primary and secondary prevention Chairs: Ola Hammarsten and ­Christian Löwbeer 10:15 –10:45 Endocrine and metabolic risk factors for cardio­ metabolic disease (202) Olle Melander, Sweden 10:45 –11:15 Novel and established kidney disease biomarkers in the prediction of cardio­ vascular disease (203) Johan Ärnlöv, Sweden 11:15 –11:45 Risk prediction of ­cardiovascular disease by high sensitive cardiac troponin assays (204) Per Venge, Sweden 11:45–12:00 Integrated Targeted Quantitation Method for Insulin and its Therapeutic Analogs (205) Ravindra Chaudhari, United States Room F2: Laboratory Point Of Care Testing – current and future challenges Small and locally available laboratory equipment gives the physician convenient and immediate access to test results. However, as the tests are often performed by untrained personnel, the test quality is often a problem. This session will discuss the current and future challenges in the quality control of Point Of Care Testing Chair: Anne-Charlotte ­W icktorsson 10:15–10:25 Introduction 10:25–10:55 Patient safety – the value of SKUP evaluations of point of care instruments (206) Elisabeth Eriksson Boija, ­Sweden 10:55–11:25 Quality assurance of the pre- and post analytical phase (207) Sverre Sandberg, Norway. 11:25–11:55 Accreditation of Point Of Care Testing, POCT, at Sahlgrenska University ­Hospital according to ISO 22870:2006 (208) Birgitta Kallberg, Sweden 11:55–12:00 Summary 12:00 8 Lunch – Exhibition and lunch seminars Room F3: Novel laboratory technology – the single molecule era Nanotechnology and other techniques now allow reliable single molecule detection that can be implemented in routine analysis. This session will cover the challenges and opportunities that this novel technology will bring to clinical laboratories Chairs: Julia Asp and Göran Larson 10:15–10:45 Analyzing biology cell by cell and molecule by molecule (209) Ulf Landegren and Masood Kamali-Moghaddam 10:45–11:15 High throughput single cell expression profiling and characterization of circulating tumor cells (210) Mikael Kubista, Sweden 11:15–11:40 A translational equine approach towards development of human biomarkers of early osteoarthritis (211) Anders Lindahl, Sweden 11:40–11:50 Establishment of a GC-MS/ MS methodology for comprehensive sex steroid profiling in mouse serum (212) Maria Nilsson, Sweden 11:50–12:00 Development and ­appli­cation of an LC-MS method with high resolution accurate masses ­detection (HRAM) with ExactivePlus mass ­spectrometer and online sample preparation (213) Valérie Thibert, France 12:30 – 13:15 Lunch seminars: Abbott Scandinavia AB Room: F1 Chairperson: Dave Ambruster, Director, Global Scientific Affairs, Abbott Diagnostics Real life experiences of new assays. HbA1c multicentre study- what do the results tell us Speaker: Johannes Lotz, Institute for Laboratory Medicine, University Hospital Mainz, Germany Our experience with High Sensitive Troponin Speakers: Clare Ford, The Royal Wolverhampton NHS Trust, New Cross Hospital, UK 12:30 – 13:15 Siemens Healthcare Diagnostics Room: F2 Elf in Liver Fibrosis Speaker: Professor W M C Rosenberg MA, MBBS, DPhil, FRCP, UCL Institute for Liver & Digestive Health, University College, UK 14:00 Afternoon Plenary session Room: F3 Chair: Göran Larson Surface-based single-liposome sensing for diagnostics and drug screening applications (214) Fredrik Höök, Sweden 14:45 Coffee and exhibition in the exhibition and poster area 15:15 Parallel Sessions Room F1: Novel diagnostic ­bio­markers in cardiology Room F2: The Astrup Prize Room F3: Next Generation Sequen­cing (NGS) in clinical diagnosis A large proportion of patients seeking health care have cardiac disease that can often be treated effectively if correctly diagnosed. This session will discuss novel diagnostic biomarkers in acute cardiac care Chairs: Ola Hammarsten and ­Christian Löwbeer The Astrup Prize is awarded to contemporary Nordic research work related to the field of clinical chemistry. The Prize is sponsored by Siemens. The winners of the Astrup prizes will be announced at the Congress Banquet Chair: Lars Melholt ­Rasmussen Next Generation Sequencing has revolutionised gene sequencing by allowing the simultaneous analysis of multiple genes, and has been optimised to such an extent that it is now possible to apply it to clinical diagnoses. In this session we will present some examples of how NGS has contributed to the identification of new gene defects linked to hereditary human diseases Chair: Jorge Asin Cayuela and Anne Ricksten 15:15–15:35 The soluble ­mannose receptor Sidsel Rødgaard-Hansen, ­D enmark 15:15–15:40 Next generation sequencing in the identification of new pathogenic ­mechanisms for mitochondrial disorders (219) Henna Tyynismaa, Finland 15:35–15:55 Comparing the diagnostic accuracies of CSF A and PET Flor­betapir Niklas Mattson, Sweden 15:40–16:05 Next Generation Sequencing in Inherited Cardiovascular Diseases (220) Lorenzo Monserrat, Spain 15:15–15:45 Copeptin-Marker of Acute Myocardial Infarction (215) Martin Möckel, Germany 15:45–16:15 PEA multiplex technology – New tools for ­clinical proteomics (216) Agneta Siegbahn, Sweden 16:15–16:30 A Multi-Center ­Analytical Evaluation of the A ­ RCHITECT STAT High Sensitive Troponin-I Assay (217) Lieselotte Lennartz, Germany 16:30–16:45 Highly Multiplexed Proteomic Analysis as a translational tool: Implications for useful biomarker discovery and early ­clinical development (218) Stephen Williams, United States 16:00 16:45 15:55–16:15 Detection of polymerized C1-inh in plasma of HAE patients – possible role in contact activation Daniel Elenius Madsen, Denmark 16:05–16:30 Genomic analysis of ­Neurodegenerative Disease (221) John Hardy, United Kingdom 16:30–16:45 Pilot study for the detection of mutations associated with­ lysosomal ­diseases using Next Generation Sequencing (222) Julia Lindgren, Sweden 16:45–17:00 The use of design programs from Sequenom when diagnosing familial hypercholesterolemia (223) Peter Benedek, Sweden SKKLF Annual Meeting Room: Nordenskiöld SSKF Annual Meeting Room: F2 Possibility for companies to arrange a social sponsor activity 9 Thursday, September 18 Breakfast seminars: 08:00– 08:45 Thermo Fisher Scientific Room: F1 Copetin – a marker of risk stratification and for early rule out in patients with suspected ACS Speaker: Dr. Joern Ole Vollert, MD., Medical Director, Thermo Fisher Scientific The latest news in molecular allergology Speaker: Robert Moverare, Principal Scientist, Thermo Fisher Scientific 08:00 – 08:45 HemoCue Room: F2 Improved workflow for efficient emergency healthcare Speaker: Younis Khalid, Chief Physician, Head of Section, Children’s ER, Drottning Silvias child- and youth hospital 09:00 Morning Plenary session Room: F3 Chair: Stefan Jacobsson Vitamin B12 deficiency. New trends in biomarkers and diagnostic strategies (301) Ebba Nexø, Denmark 09:45 Coffee and exhibition in the exhibition and poster area 10:15 Parallel Sessions Room F1: Rare disorders of erythrocytes. The dys­ regulation of iron and ferritin homeostasis Room F2: Biomarkers in diagnosis of neurodegenerative diseases Dysregulation of the fine-tuned systemic and/or local iron homeostasis is emerging as an under­ lying cause of haematological and neurodegenerative diseases. Various forms of hereditary hemochromatosis with low hepcidin expression and iron-refractory iron deficiency anaemia with high hepcidin expression are attributed to mutations affecting the hepcidin-mediated control of the regulation of ferroportin. This session will give an overview of the molecular mechanisms behind rare hereditary disorders of the red blood cell. The aim is to achieve a better understanding of how to use the different available diagnostic tools Chairs: Linda Fogelstrand and Stefan Jacobsson Neurodegenerative disorders constitute a pleiotropic group of diseases that are often hard to distinguish from one another, without knowledge of the under­ lying pathology, as they often present with similar symptoms. This session will focus on the research frontier of the use of novel biomarkers in the diagnosis of neurodegenerative disorders Chair: Henrik Zetterberg 10:15–10:45 Hereditary hemochromatosis and ferroportin disease (302) Sandro Altamura, Germany 10:45–11:15 Neurological disorders of iron homeostasis: neurodegeneration with brain iron accumulation (NBIA) and neuroferritinopathies (303) Paolo Arosio, Italy 11:15–11:45 Why do we make mistakes in the morphological interpretation of blood slides and how can we improve? (304) John Burthem, United Kingdom 11:45–12:00 Bloodhound Technology™ – Returning to the roots of Hematology (305) Mark Fellmann, Switzerland 12:00 10 10:15–10:45 CSF and plasma biomarkers for Alzheimer’s ­disease – use for diagnostics and ­theragnostics (306) Kaj Blennow, Sweden 10:45–11:15 Emergening molecular diagnostics tools for Alzheimer’s (AD) and other neurodegenerative diseases (307) Niels H. H. Heegaard, ­ Denmark 11:15–11:45 Single Molecule Arrays (Simoa) for Ultrasensitive, Multiplexed Detection of ­Proteins and Nucleic Acids (308) David Hanlon, United States Lunch – Exhibition and lunch seminars Room F3: The future clinical l­aboratory as a ­diagnostic ­partner The expansion of our knowledge of disease mechanisms and novel biomarkers is expected to increase the interaction between experts in the clinical laboratory and physicians. This session will discuss what will be expected from the laboratoryas a diagnostic partner in future medicine Chair: Per Simonsson and Birgitta Kallberg 10:15–10:40 The ­Cinderellas of health care (309) Mirja Mindemark, ­Sweden 10:40–11:05 The future clinical laboratory as ­diagnostic partner (310) Martina Jürs, Denmark 11:05-11:30 Do you read me? – Radio check for clinical ­chemists. (311) Per Simonsson, Sweden 12:30– 13:15 Lunch seminars: Roche Diagnostics AB Room: F1 Panel discussion: True value of labs within the healthcare system Speakers: Tor-Arne Hagve, Physician Medical biochemistry, Laboratory Medical Centre, Akershus, Oslo. Göran Larson Professor, Head of Core Facilities Sahlgrenska Akademin. Robert Sinclair MD, Ph.D, DTM&H, Senior Medical Advisor, Dept. of Health Care Region Västra Götaland. Srinivas Uppugunduri Professor, Head of Dept. of Clinical Chemistry, Östergötland. Kasper Iversen Ph.D, MD, Cardiologist Head Physician, Kardiologisk afdeling, Herlev. Magnus Göransson General Manager, Roche Diagnostics, Sweden. 12:30 – 13:15 Sysmex Sverige Room: F2 Better staining. Better diagnostic morphology. Three Ways Speaker: Henricus Jansen, Marketing Diagnostic Concepts & Lab Solutions, Sysmex Europe 14:00 Afternoon Plenary session Room: F3 Chair: Henrik Zetterberg Blood based biomarkers for Alzheimer’s disease – from case control to endophenotype discovery and from small to large, potentially huge, replication (312) Simon Lovestone, United Kingdom 14:45 Coffee and exhibition in the exhibition and poster area 15:15 Parallel Sessions Room F1: Laboratory diagnostics of myelo­ proliferative neoplasms Our understanding of the molecular changes that lead to the development of different myeloproliferative neoplasms (MPN) has developed rapidly, through the discovery of activating mutations in several genes responsible for the regulation of cell differentiation and proliferation (e.g. the JAK2 gene but also, very recently, the CALR gene). This has led to new diagnostic and therapeutic opportunities but also to new challenges. This session will give a background and update of the laboratory diagnostic of MPN and suggestions on how to integrate new genetic findings in diagnostic algorithms Chairs: Linda Fogelstrand and Lars Palmqvist 15:15–15:45 Perspectives on chronic inflammation in essential thrombocythemia, polycythemia vera, and myelofibrosis: is chronic inflammation a trigger and driver of clonal evolution and development of accelerated atherosclerosis and second cancer? (313) Hans Hasselbalch, Denmark 15:45–16:15 Laboratory Diagnostics of Myelo­ proliferative Neoplasms (314) Susanne Schnittger, Germany 16:15–16:30 Frequency of CALR mutations and correlation with laboratory findings and clinical outcome in Essential Thrombocythaemia and ­Primary Myelofibrosis patients (315) Julia Asp, Sweden 16:30–16:45 European JAK2V617F interlaboratory quality control study carried out by the MPN&MPNR-­EURONET (COST ACTION BM0902) (316) Niels Pallisgaard, Denmark Room F2: The Eldjarn Prize The Lorentz Eldjarn Prize Competition is financed by a Fund established by Professor Lorentz Eldjarn and his wife Torunn in 2009, to reward the best article published in Scand J Clin Lab Invest during the five years preceding the prize year. The Prize Committee has nominated three articles based on the scientific quality of the studies and the clarity of the presentations. The recipients of the prize will be announced at the Congress banquet Chair: Jens P Berg 15:15–15:40 Vitamin D and PTH – ­seasonal and age-related variations (317) Monika Christensen, ­N orway 15:40–16:05 Biomarkers of alcohol use and related health risks (318) Onni Niemelä, Finland 16:05–16:30 Soluble CD163 – a biomarker of macrophage activation in disease (319) Holger Jon Møller, Denmark Room F3: Organisation of the future clinical laboratory As laboratory medicine has converged during the past decade, it now possible to merge several aspects of the clinical laboratory. This merger will need different IT solutions for different platforms. This session will discuss opportunities and potential problems in this process Chairs: Birgitta Kallberg and Anders Lindahl 15:15–15:35 Opportunities and pitfalls when ­integrating laboratory ­disciplines (320) Andreas Matussek, ­Sweden 15:35–15:55 The future of Lab ­M edicine seen through the eyes of a Niche ­Supplier (321) Jørgen Viktil, Norway 15:55–16:15 Clinical Chemistry towards the future-where to go? (322) Anders Lindahl, Sweden 16:15–16:30 Panel ­discussion 16:45–17:00 SFKK Annual Meeting Room: F1 19:30 Banquet “Glitter and Glamour” Estrad Restaurant, Mässans gata 5. Entrance 5 11 Friday, September 19 09:00 Morning Plenary session Room: F3 Chair: Anne Ricksten Application of massively parallel sequencing (MPS) for clinical analyses: challenges and opportunities (401) Ulf Gyllensten, Sweden 09:45 Coffee and exhibition in the exhibition and poster area 10:15 Parallel Sessions Room F1: Clinical laboratory education today and tomorrow Room F2: Future use of ­cancer biomarkers Room F3: Biomarkers of kidney disease The different professions within laboratory medicine complement each other. The education programs are under development and revision. Future laboratory medicine will be dynamic with new biomarkers and techniques. This session will illustrate the situation within the Nordic countries Chairs: Mats Ohlson and Camilla Hesse Our knowledge of how cancer develops and evolves into stable tissue has recently been rewritten. In addition, several cancer biomarkers are now used for screening and to guide personalised treatment. This session will give an overview of our new vistas in cancer biology and provide examples of future cancer biomarkers that will aid in the diagnosis and treatment of cancer Chairs: Julia Asp and Anne Ricksten How to estimate kidney function has been debated for decades. Recently, ways to standardise the measurement of cystatin C have been presented, and new better formulae for both creatinine and cystatin C-based estimations of the GFR have been developed. This session will discuss how kidney function should be measured. In addition, novel methods for the measurement of carbohydrate urine markers and how cardiac markers might be affected by kidney function will be discussed Chairs: Ola Hammarsten and Anders Larsson 10:15–10:45 Do you think (cancer) medicine is modern? The need for a new cancer­ paradigm (407) Ingemar Ernberg, Sweden 10:15–10:45 Biomarkers of Kidney Disease (411) Anders Grubb, Sweden 10:15–10:30 Collaborative Design of Educational Model for Clinical Biochemists in Swedish Laboratory Medicine – “The Swedish Model” (402) Tom M Pettersson, Sweden 10:30–10:40 Training of Clinical Biochemists in Finland (403) Päivi Laitinen, Finland 10:40–10:55 Biomedical ­laboratory science, present and future aspects on the education (404) Camilla Hesse, Sweden 10:45–11:15 Combined assessment of six Tumor ­Markers for the Diagnosis and Histological Diagnosis of Lung Cancer (408) Rafael Molina, Spain 10:55–11:05 Clinical laboratory education today and tomorrow – the Swedish physician’s ­perspective (405) Christian Löwbeer, Sweden 11:15–11:45 Biomarkers increase survival in ovarian ­cancer (409) Karin Sundfeldt, Sweden 11:05–11:20 Specialist training in the Nordic Countries and the ­Danish model (406) Nete Hornung, Denmark 11:20–11:30 Panel discussion 12:00 12 11:45–12:00 Elevated plasma Cobalamin Predicts a Poor ­Survival for Cancer Patients – a Population-based Cohort Study (410) Johan Frederik Berg Arendt, Denmark 10:45–11:15 Simple protocol for preparation and nLC-MS/MS characterization of proteoglycan linkage region glycopeptides of human plasma, urine and cerebrospinal fluid samples (412) Göran Larson, Sweden 11:15–11:25 Cystatin C-based GFR is more closely associated with mortality than creatinine-based GFR in un­selected patients seeking health care (413) Johanna Helmersson-Karlqvist, ­Sweden 11:15–11:35 Troponin I levels are less dependent on glomerular filtration rate compared to Troponin T and other cardiac biomarkers (414) Christian Bjurman, Sweden Poster Prize winning cermony and Closing Remarks Room: F3 Posters list Biomarkers in heart disease P01 Lipoprotein(a), total/HDL-cholesterol ratio, ApoB/ApoA ratio as risk factors for atherogenesis in patients with coronary artery disease Danica Labudovic, Sonja Alabakovska, Katerina Tosheska Trajkovska, Jasna Bogdanska, Silvana Jovanova P02 High Sensitive Troponin in patients with Erectile Dysfunction Gianvico Melzi D’eril, Raffaele Pezzilli, Clara A. L. Damele, Rossana Stefanelli, Giovanni M. Colpi, ­Massimiliano M. Corsi Romanelli, Alessandra Barassi P03 Acute pancreatitis and myocardial damage GianVico Melzi d’Eril, Raffaele Pezzilli, Giovanni M. Colpi, Massimiliano M. Corsi Romanelli, ­Alessandra Barassi P04 Quality assurance measurement of the cholesterol markers apolipoproteins A1 and B; Going against the grain Joannis Kinalis, Eva Fahlen, Erika Langenstam, Erika Karabasic P05 Evaluation of the Alere NT-proBNP test for point of care testing Banafsheh Seyyed Khezri, Lena Carlsson, Anders Larsson P06 Serial Troponin T testing based on stored samples in the clinical laboratory Oscar Oliva Torstensson, Carina Gustafsson, Birgitta Gren, Jan Friden, Ola Hammarsten P07 Implementation of cardiac biomarkers in ambulatory emergency medicine department Vaike Viia P07:2 Estimation of the possible economic effects of a sequential testing strategy with NT-proBNP before echocardiography in primary care Banafsheh Seyyed Khezri, Johanna Helmersson-Karlqvist, Anders Larsson Novel techniques P08 An invitro assay to measure cell sensitivity to ionizing radiation Sherin Mathew, Pegah Johansson, Ola Hammarsten P09 An improved high performance liquid chromatography-fluorescence detection method for the analysis of Pimozide in human plasma samples Alessandra Barassi, Francesca Ghilardi, Alessandra Flaminio, Roberta Marotta, GianVico Melzi d'Eril P10 Validation of a new OptiScanner™ 5000 system for an intermittent glucose monitoring Alessandra Barassi, Michele Umbrello, Clara A. L. Damele, Francesca Ghilardi, Rossana Stefanelli, Gaetano Iapichino, GianVico Melzi d'Eril P11 Preparation and in vitro evaluation of doxorubicin-loaded Fe3O 4 magnetic nanoparticles modified with biocompatible copolymers Abolfazl Akbarzadeh P012 Amyloidosis diagnosis by mass spectrometry Jakob C. Albrethsen, Morten Salomo, Anders H. Johnsen 13 Biomarkers in neurodegenerative disease P13 Plasma levels of apolipoprotein E and risk of dementia in the general population Katrine Laura Rasmussen, Anne Tybjærg-Hansen, Børge G. Nordestgaard, Ruth Frikke-Schmidt P14 Blood biomarkers for brain injury in concussed professional ice hockey players Pashtun Shahim, Gisela Malmgård, David H. Wilson, Jeffrey Randall, Birgitta Kallberg, Yelverton ­Tegner, Kaj Blennow, Henrik Zetterberg P15 Biomarker-determined Alzheimer prevalence in patients undergoing surgery due to hip ­fracture Maria Lönnquist, Birgitta Kallberg, Kaj Blennow, Henrik Zetterberg, Bengt Nellgård Laboratory as a diagnostic partner 14 P16 Critical results for community based patients and audit of a two tier biochemical phone list Jeffrey Barron, Geoff Smith P017 HbA1c as the diagnostic criterion for diabetes reduces incidence and prevalence of DM2 by 25% but strongly depending on analytical quality Ivan Brandslund, Aneta A. Nielsen, Per H. Petersen, Anders Green, Cramer K. Christensen, Henry Christensen P018 Ensuring faster patient treatment by reducing turn-around-time for laboratory results Carsten Thomsen, Claus Brasen, Christian U. Maegaard, Nina Mogensen, Ivan Brandslund P019 Vitamin D in patients with pancreatic diseases Gianvico Melzi D’eril, Alessandra Barassi, Raffaele Pezzilli P20 Vitamin D and Erectile Dysfunction Alessandra Barassi, Raffaele Pezzilli, Clara A. L. Damele, Rossana Stefanelli, Giovanni M. Colpi, ­Massimiliano M. Corsi Romanelli, GianVico Melzi d’Eril P21 Assessing the mitochondrial iron metabolism in hereditary hemochromatosis Sonia Distante, Ragnhild Skinnes, Kari Høie, Lars Mørkrid, Lars Eide P22 The Role of Early Evaluation of Porphyrins in Diagnosis of Acute Porphyria Galina Zemtsovskaja, Agnes Ivanov, Marika Pikta P23 Can Morning Serum Cortisol Ranges and Action Limits be Harmonised? Robert Wardrop, Narelle Hadlow P24 An Alpha-Thalassemia Case in Estonia Marika Pikta, Galina Zemtsovskaja, Iige Viigimaa, Jelena Jerjomina P25 Use of Pyrosequencing for the Detection of Several Polymorphisms Associated with Lactase Persistence Catherine Herrera, Gunnhild Kravdahl, Malene Nilsen Biomarker development P26 Effect of fasting on plasma levels of 7-alpha-hydroxy-4-cholesten-3-one – a marker for bile acid synthesis in humans Magnus Axelson, Kerstin Brismar P27 Detection of antinuclear antibodies – a comparison of indirect immunefluorescence on HEp-2 cells and fluoroenzymeimmunoassay (EliA CTD screen, Thermo Fisher) Lone Nørgård Troelsen, Søren Jacobsen, Lina Pedersen P28 Measuring gamma-H2AX as a biomarker for DNA damage after ionizing radiation treatment in cancer patients Pegah Johansson, Aida Muslimovic, Ragnar Hultborn, Erik Fernström, Ola Hammarsten P29 Novel Circulating isoforms of hepcidin Morten Moe, Tor-Arne Hagve, Ingrid M. Hardang P30 Early diagnosis and calculating the risk of ovarian cancer in women by combining the results of two biomarkers HE4 & CA125 Aaso Raoofi, Adam Molner, Fereshteh Pourlotfi, Tatyana Danylchenko Hematology P31 Assessment of a diagnostic algorithm to classify von Willebrand disease Karin Littmann, Maria Berndtsson, Eva-Marie Norberg, Jovan Antovic P32 Trypan Blue accurately defines the viability of CFU-GM cells in Cord Blood Units Sofia U. Frändberg, Eva Anghem, Inger Ögärd, Lars Palmqvist P33 Exploring the heterogeneity of the hematopoietic stem cell pool: A simultaneous ­staining protocol for the Side population, Aldehyde dehydrogenase and CD34 in Cord Blood Sofia U. Frändberg, Susann Li, Cecilia Boreström, Lars Palmqvist P34 Are hemoglobin variants eluting in “variant window” on Bio-Rad Variant Turbo 2.0 affecting the HbA1c results? Britta Landin, Lena Fredriksson P35 The usefulness of the “Imm Gran?” flag reported on by the Sysmex XE-5000 Heidi Eilertsen, Tor-Arne Hagve P36 Hypersegmentation in a routin laboratory– a common finding or not? Anna Maj Ericsson, Helena Orre-Ekdahl, Stefan Jacobsson P37 Evaluation of ‘CellaVision Advanced RBC application’; new software for reporting ­erythrocyte morphology Eva Grönlund, Margit Döry, Agnetha Evers, Soheir Beshara P38 Interference of Monoclonal Antibody Therapies with Serum Protein Electrophoresis Analysis Claus Brasen, Jakub Krejcik, Torben Plesner P39 Whole exome sequencing of sorted leukemic cells as a complementing method in genetic ­characterization of acute myeloid leukemia Erik Malmberg, Sara Ståhlman, Sofie J. Alm, Tore Samuelsson, Lars Palmqvist, Linda Fogelstrand 15 Point of care testing P40 Evaluation of HemoCue WBC DIFF system versus Sysmex XE in blood samples from pediatric patients Anette Friis Larsen, Ole Halfdan Larsen, Anne Dorthe Møller, Søren Ladefoged, Tore Hardlei P41 Harmonizing POCT and Central Core Laboratory analyzers Anne-Charlotte Wicktorsson, Maria Thornemo P41:2 Assuring quality in point-of-care testing at the Sahlgrenska University Hospital Anne-Marie Johannesson, Ingrid Uttberg, Maria Thornemo P42 Centralized vs. decentralized blood collection: A comparison of quality indicators for the p ­ reanalytical phase Erik K. Amundsen, Solrun Fransen, Gro Siri B. Lillesund, Tonje V. Larsen, Karin Toska P43 Like Herding Cats – Information Technology Facilitates Management of Point of Care Testing Systems Nicole Carney, Robert Dodds, Katrina Moreau, Gregory Sharp P44 Evaluation of three different CRP Point of Care Testing instruments Slavena Mandic, Marie Palmblad, Laura Goobar Larsson Laboratory education P45 Clinical chemistry practice in Republic of Macedonia Jasna Bogdanska, Danica Labudovic Novel company technology P46 Keeping Bacteria Under Control to Minimize Impact on Assays and Maximize Analyzer Uptime Stephane Mabic, Maryse Gauthey Baraou, Johan Thorell Other 16 P47 Integrated EQA Jonna Pelanti, Samuli Niiranen P48 Method comparison of three automated 25-hydroxy vitamin D enzyme immunoassays to l­iquid chromatography tandem mass spectroscopy (LCMS/MS) and against each other Nada Rakovan, Trine Lauritzen, Per O. Nordstrøm, Øyvind Skadberg P49 Automated alarm to detect antigen excess in serum free immunoglobulin light chain kappa and lambda assays – Experience from routine application Karin Toska, Erik K. Amundsen, Petter Urdal, Olav Klingenberg P50 Haemolysis in underfilled venipuncture testtubes Birgitta Gren P51 Reproducibility problem in an ELISA assay method – fibroblast growth factor 23 (FGF-23) as an example Henrik Alfthan, Helene Markkanen, Esa Hämäläinen P52 Efficient extraction of human DNA from stool samples and detection of genetic and ­epigenetic alterations specific for colorectal neoplasia Aleksandra Mandic Havelka, Annelie Strålfors, Lars-Olof Hansson, Ulrik Lindfors, Gösta Eggertsen P53 PAPP-A2. Median values in normal pregnancy in first trimester and association to Small-For-Gestational-Age infants Young Bae Hansen, Vibeke Myrhøj, Finn S. Jørgensen, Claus Oxvig, Steen Sørensen P54 Comparison of two methods for determination of coagulation factor VIII activity Susanne Samuelsson P55 Evaluation of Technopath Controls on the ARCHITECT Family of Instruments Jessie Shih, Didier Brault, Antonio Croce, Lieselotte Lennartz, Matthias Orth P56 Comparison of the results of immunoglobulin (IgA,IgG,IgM), IgG subclasses and specific ­antibodies of patients with frequent sinopulmonary problems Elo Saue P57 Clinical chemical monitoring of PFIC-patients treated with a new surgical method Karin Littmann, Cecilia Gälman, Paolo Parini, Björn Fishler, Antal Nemeth, Eva Beijer, Maria M ­ agnusson, Ronald Oude-Elferink, Gösta Eggertsen P58 Hidden asymptomatic CDG cases may be mistaken for excessive alcohol consumption Anders Helander, Jaak Jaeken, Gert Matthijs, Gösta Eggertsen P59 Up-regulation of Liver Enriched Transcription Factors (HNF4a and HNF6) and Liver ­Specific MicroRNA (MiR-122) by Inhibition of Let-7b in Mesenchymal Stem Cells Nosratollah Zarghami, Effat Alizadeh, Abolfazl Akbarzadeh, Mohamadreza Baghaban Eslaminejad, Kazem Nejati-Koshki P60 Kidney stone analysis by FTIR Morten Moe, Marianne Moe, Gunnhild Kravdal P61 Sigma metrics used to assess analytical quality of clinical chemistry assays: Importance of the allowable total error (TEa) target Dave Armbruster, Sten A. Westgard P62 Inhibitory Effects of β-Cyclodextrin-Helenalin Complexes on H-TERT Gene Expression in the T47D Breast Cancer Cell Line – Results of Real Time Quantitative PCR Faraz Zarghami, Abolfazl Akbarzadeh P63 Effect of rest time prior to blood sampling on common biochemical parameter – results from thyreotropin Ida B. Andersen, Claus L. Brasen, Lene Nohr-Jensen, Dorthe E. Nielsen, Jonna S. Madsen P64 Serum 25-hydroxyvitamin D below 75 nmol/L observed in 75% of healthy Swedish audults ­during 75% of the year Göran Oleröd, Eva Klingberg, Jan Konar, Max Petzold , Ola Hammarsten P65 Effect of apixaban on common coagulation analyses Inger Fagerberg Blixter and Equalis 17 Author index A Aggerholm, Anni 316, P316 Beijer, Eva P57 Akbarzadeh, Abolfazl P11, P59, P62 Bellosillo, Beatriz 316, P316 Alabakovska, Sonja P01 Benedek, Peter 223, P223 P12 Bergo, Martin O. 103 Alfthan, Henrik P51 Berndtsson, Maria P31 Alizadeh, Effat P59 Beshara, Soheir P37 Alm Johansson, Sofie P39 Bjurman, Christian 414, P414 Almås, Bjørg 317 Blennow, Kaj 306, P14, P15 Altamura, Sandro 302 Bogdanska, Jasna P01,P45 Amundsen Koldberg, Erik P42, P49 Borén, Jan 101 Andersen Boegh, Ida P63 Boreström, Cecilia P33 Andersen Tolstrup, Morten 316, P316 Boudry, Pascal 217, P217 Andréasson, Björn 315, P315 Brandslund, Ivan P17, P18 316, P316 Brasen Lohmann, Claus P63 223, P223 Brasen, Claus P18, P38 P32 Brault, Didier P55 P31 Brismar, Kerstin P26 205, P205 Brody, Ed 218, P218 410, P410 Bryon, Jane 316, P316 Armbruster, Dave P61 Burthem, John 304 Ärnlöv, Johan 203,413, P413 Asin Cayuela, Jorge 222, P222 Asp, Julia 315, P315, 316, P316 Carlsson, Lena P05 Carney, Nicole P43 Axelson, Magnus P26 Cassinat, Bruno 316, P316 Ayala, Rosa 316, P316 Chaudhari, Ravindra 205, P205 Christensen Kjeldahl, Cramer P17 Christensen, Henry P17 Christensen, Monika H.E. 317 Colpi, Giovanni M P02, P03, P20 Corsi Romanelli, Massimiliano M P02, P03, P20 Coudoré, François 213, P213 Croce, Antonio P55 Albrethsen, Jakob C. Andrikovics, Hajnalka Angelin, Bo Anghem, Eva Antovic, Jovan Antwi, Kwasi Arendt, Johan Frederik Berg B Baghaban Eslaminejad, Mohamadreza Barassi, Alessandra 18 P59 P02, P03, P09, P10, P19, P20 Barron, Jeffrey P16 Bauer, Timothy 218, P218 C G D Damele, Clara Anna Linda P02, P10, P20 Gauthey Baraou, Maryse P46 Danylchenko, Tatyana P30 Ghilardi, Francesca P09, P10 Dicker, Frank 316, P316 Girodon, François 316, P316 Distante, Sonia P21 Gomez Toledo, Alejandro 412, P412 Dodds, Robert P43 Goobar Larsson, Laura P44 Duvefelt, Kristina 223, P223 Green, Anders P17 Döry, Margit P37 Gren, Birgitta P06, P50 Grubb, Anders 411 Grönlund, Eva P37 E Eggertsen, Gösta P52, P57, P58 Gustafsson, Carina P06 Eide, Lars P21 Gyllensten, Ulf 401 Eilertsen, Heidi P35 Gälman, Cecilia P57 Ericsson, Anna Maj P36 Eriksson Boija, Elisabet 206 Eriksson, Mats 223, P223 Hadlow, Narelle P23 Ernberg, Ingemar 407 Hagve, Tor-Arne P29,P35 Estan, Nuria 217, P217 Hammarsten, Ola Evers, Agnetha P37 414, P414, P06, P08, P28, P64 Hanlon, David 308 Hansen, Young Bae P53 P52 F H Fagerberg Blixter, Inger P65 Hansson, Lars-Olof Fahlen, Eva P04 Hansson, Ulrika 315, P315 Farkas Körmendiné, Dóra 410, P410 Hardang, Ingrid M P29 Fellmann, Mark 305, P305 Hardlei, Tore P40 Fernström, Erik P28 Hardy, John 221 Finazzi, Dario 303 Hasselbalch, Hans 313 Fishler, Björn P57 Hasselbalch, Hans Karl 316, P316 P09 Heegaard, Niels 307 P39 Helander, Anders P58 P42 Helmersson-Karlqvist, Johanna 413, P413, P07:2 P34 Hermouet, Sylvie 316, P316 P06 Herrera, Catherine P25 P40 Hesse, Camilla 404 P13 Høie, Kari P21 P32, P33 Hornung, Nete 406 414, P414 Hultborn, Ragnar P28 Flaminio, Alessandra Fogelstrand, Linda Fransen, Solrun Fredriksson, Lena Friden, Jan Friis Larsen, Anette Frikke-Schmidt, Ruth Frändberg, Sofia Ulrika Fu, Michael 19 317 Hämäläinen, Esa P51 Labudovic, Danica P01, P45 Höök, Fredrik 214 Ladefoged, Søren P40 Laitinen, Päivi 403 Landegren, Ulf 209 I Iapichino, Gaetano P10 Landin, Britta P34 Ivanov, Agnes P22 Langenstam, Erika P04 Larsen Versvik, Tonje P42 Larsen, Ole Halfdan P40 J Jacobsen, Søren P27 Larson, Göran 412, P412 Jacobsson, Stefan P36 Larsson, Anders Jaeken, Jaak P58 413, P413, P05, P07:2 Jerjomina, Jelena P24 Lauritzen, Trine P48 Johannesson, Anne-Marie P41:2 Leber, Amanda 205, P205 Johansson, Pegah P08, P28 Lefèvre, Guillaume 217, P217 Johansson, Peter 315, P315 Leibundgut Oppliger, Elisabeth 316, P316 Johnsen, Anders H. P12 Lemonnier, Alban 213, P213 Jørgensen, Finn Stener P53 Lennartsson, Ann-Britt 305, P305 Jovanova, Silvana P01 Lennartz, Lieselotte 217, P217,P55 Jürs, Martina 310 Lewandowski, Krzysztof 316, P316 Li, Susann P33 Lien, Ernst A. 317 K 20 L Hustad, Steinar Kallberg, Birgitta 208, P14, P15 Lillesund Birkeland, Gro Siri P42 Karabasic, Erika P04 Lindahl, Anders 211, P211,322 Kere, Juha 223, P223 Lindahl, Bertil 201 Kiernan, Urban 205, P205 Lindahl, Per 103 Kinalis, Joannis P04 Linde, Malin 223, P223 Kjær, Lasse 316, P316 Lindfors, Ulrik P52 Kjellström, Birgitta 222, P222 Lindgren, Julia 222, P222 Klingberg, Eva P64 Lippert, Eric 316, P316 Klingenberg, Olav P49 Littmann, Karin P31,P57 Konar, Jan P64 Lodé, Laurence 316, P316 Krastins, Bryan 205, P205 Lopez, Mary 205, P205 Kravdahl, Gunnhild P25, P60 Lotz, Johannes 217, P217 Krejcik, Jakub P38 Lovestone, Simon 312 Krintus, Magdalena 217, P217 Lönnquist, Maria P15 Kristensen Kielsgaard, Thomas 316, P316 Löwbeer, Christian 405 Kubista, Mikael 210 Köller, Ursula 217, P217 M Mabic, Stephane P46 Madsen Skov, Jonna P63 Maegaard, Christian Ulrik P18 Magnusson, Maria P57 Nilsson, Åsa 222, P222 Malmberg, Erik P39 Nilsson, Jonas 412, P412 Malmgård, Gisela P14 Nilsson, Maria 212, P212 Mandic Havelka, Aleksandra P52 Noborn, Fredrik 412, P412 Mandic, Slavena P44 Nohr-Jensen, Lene P63 Markkanen, Helene P51 Nomdedéu, Josep 316, P316 Marotta, Roberta P09 Norberg, Eva-Marie P31 Marusic, Maruska 316, P316 Nordestgaard, Børge G P13 Mathew, Sherin P08 Nordstrøm, Per Olov P48 Matthijs, Gert P58 Norlén, Anna-Karin 212, P212 Matussek, Andreas 320 Nybo, Mads 217, P217 Mehler, Bob 218, P218 Melander, Olle 202 Melzi D'eril, Gianvico P02, P03, P09, P10, P19, P20 Ohlsson, Claes 212, P212 Oleröd, Göran P64 Mindemark, Mirja 309 Oliva Torstensson, Oscar P06 Moe, Marianne P60 Orre-Ekdahl, Helena P36 Moe, Morten P29,P60 Orth, Matthias P55 Mogensen, Nina P18 Oude-Elferink, Ronald P57 Molina, Rafael 408 Oxvig, Claus P53 Møller, Anne Dorthe P40 Møller, Holger Jon 319 Molner, Adam P30 Pallisgaard, Niels 316, P316 Monserrat, Lorenzo 220 Palmblad, Marie P44 Moreau, Katrina P43 Palmqvist, Lars Mørkrid, Lars P21 315, P315, P32, P33, P39 Muslimovic, Aida P28 Pancrazzi, Alessandro 316, P316 Myrhøj, Vibeke P53 Paolo, Arosio 303 Månsson, Jan-Eric 222, P222 Parini, Paolo P57 Möckel, Martin 215 Pedersen, Lars 410, P410 Pedersen, Lina P27 Pelanti, Jonna P47 N O P Naguib, Dina 316, P316 Percy, Melanie 316, P316 Nejati-Koshki, Kazem P59 Peterman, Scott 205, P205 Nellgård, Bengt P15 Petersen Hyltoft, Per P17 Nemeth, Antal P57 Pettersson, Tom 402 Nexø, Ebba 301,410, P410 Petzold, Max 414, P414, P64 Niederkofler, Eric 205, P205 Pezzilli, Raffaele P02, P03, P19, P20 Nielsen Elkjaer, Dorthe P63 Pikta, Marika P22, P24 P17 Plebani, Mario 217, P217 318 Plesner, Torben P38 P47 Pourlotfi, Fereshteh P30 P25 Prakash, Amol 205, P205 Nielsen, Aneta Alexandra Niemelä, Onni Niiranen, Samuli Nilsen, Malene 21 R Thornemo, Maria P41, P41:2 Rakovan, Nada P48 Tivesten, Åsa 212, P212 Randall, Jeffrey P14 Tosheska Trajkovska, Katerina P01 Raoofi, Aaso P30 Toska, Karin P42,P49 Rasmussen, Katrine Laura P13 Troelsen, Lone Nørgård P27 Ryberg, Henrik 212, P212 Tubbs, Kemmons 205, P205 Tybjærg-Hansen, Anne P13 Tyynismaa, Henna 219 S Salomo, Morten P12 Samuelson, Emma 222, P222, 316, P316 Umbrello, Michele P10 Samuelsson, Susanne P54 Urdal, Petter P49 Samuelsson, Tore P39 Uttberg, Ingrid P41:2 Sandberg, Sverre 207 Saue, Elo P56 Sayin, Volkan 103 Vandenput, Liesbeth 212, P212 Schnittger, Susanne 314 Venge, Per 204 Schroeder, Tara 205, P205 Viia, Vaike P07 Schwarz, Jiri 316, P316 Viigimaa, Iige P24 Seyyed Khezri, Banafsheh P05, P07:2 Viktil, Jørgen 321 Shahim, Pashtun P14 Vorland, Marta 316, P316 Sharp, Gregory P43 Shih, Jessie 217, P217, P55 Siegbahn, Agneta 216 Wardrop, Robert P23 Simonsson, Per 311 Wasslavik, Carina 315, P315 Singer, Britta 218, P218 Westgard, Sten Anders P61 Skadberg, Øyvind 217, P217, P48 Wicktorsson, Anne-Charlotte P41 Skinnes, Ragnhild P21 Williams, Stephen 218, P218 Smith, Geoff P16 Wilson, David H P14 Sørensen Toft, Henrik 410, P410 Wold, Agnes 102 Sørensen, Steen P53 Ståhlman, Sara P39 Stefanelli, Rossana P02,P10,P20 Zarghami, Faraz P62 Sterling, David 218, P218 Zarghami, Nosratollah P59 Strålfors, Annelie P52 Zemtsovskaja, Galina P22,P24 Sundfeldt, Karin 409 Zetterberg, Henrik P14,P15 Tegner, Yelverton P14 Ärnlöv, Johan Thibert, Valérie 213, P213 Thomsen, Carsten P18 Thorell, Johan P46 T 22 U V W Z Ä Ö Ögärd, Inger P32 Roche Diagnostics Seminars Program Wednesday, September 17 8:30-9:00 (Booth) The value of NT-proBNP in the monitoring and treatment of heart failure patients Åke johansson M.D. Specialist Allmänmedicin Askim Vårdcentral Göteborg Thursday, September 18 8:30-9:00 (Booth) New hematology instruments from Roche cobas m511 (Bloodhound technology) Mark Fellmann Ph.D., Int Produktchef Hematologi Roche 9:45-10:15 The value of NT-proBNP in the monitoring (Booth) and treatment of heart failure patients Åke johansson M.D. Specialist Allmänmedicin Askim Vårdcentral Göteborg 9:45-10:15 New hematology instruments from Roche (Booth) cobas m511 (Bloodhound technology) Mark Fellmann Ph.D., Int Produktchef Hematologi Roche 11:30-12:00 Evaluation of the CoaguChek XS for analysis (Booth) of PK(INR) taken by capillary sampling Maria Tornemo M.D.Ph.D., Annika Björk Leg. BMA Klinisk Kemi Sahlgrenska Universitetsjukhuset 10:15-11:30 The future clinical laboratory as diagnostic (Conference partner program) Mirja Mindemark, PhD, Senior Account Manager, Roche Diagnostics Scandinavia AB 12:30-13:00 Evaluation of the CoaguChek XS for analysis (Booth) of PK(INR) taken by capillary sampling Maria Tornemo M.D.Ph.D., Annika Björk Leg. BMA Klinisk Kemi Sahlgrenska Universitetsjukhuset 12:30-13:15 Lunchseminarium, (F1) Paneldebatt med fokus på hur sjukvården 14:45-15:15 High-sensitivity troponin T provides faster (Booth) and better care for chest pain Dina Melki M.D., Ph.D. Avd för Kardiologi Karolinska Universitetssjukhuset 14:45-15:15 S100B; Biomarker in new guidelines for (Booth) traumatic brain injury Eric elin, M.D., Ph.D.-doktorand Avd. för Neurokirurgi Karolinska Universitetssjukhuset kan dra mer nytta av laboratoriemedicin Friday, September 19 9:45-10:15 S100B; Biomarker in new guidelines for (Booth) traumatic brain injury Eric elin, M.D., Ph.D.-doktorand Avd. för Neurokirurgi Karolinska Universitetssjukhuset 23 Guidelines for Speakers The Speakers Preview Room is located outside Room 1. Speakers are kindly requested to provide their PC-formatted USB keys (PowerPoint presentations) to the staff in the Speakers room, preferably the day before, or at least 2 hours prior to the presentation. The lecture room is equipped with data projection equipment. File format: Microsoft Power Point or Adobe Acrobat formatted for Windows (PC). Preferred Resolution: XGA (1024 x 768) Technical staff will be available in the Conference room as follows: Tuesday 16th 11.00 –15.30 Wednesday–Thursday 17th & 18th 07.30–16.30 Friday 19th 08.00–11.30 ! Good to know Prepare your presentation in good time. If you have film sequences in your presentation be sure that they function when you have transferred them into the NFKK computer system. In respect to Your fellow Oral Presenters be at the first row seats 15 minutes prior to the start of Your session and announce Your presence to the Chairman of Your session. 24 WE ARE SHARING OUR KNOWLEDGE – JOIN US! “Better staining. Better diagnostic morphology. Three Ways.” Thursday 18 September 12:30 – 13:15, Meetingroom F2 Come visit us at booth #14 and win an iPod nano* ! We pride ourselves on being a knowledge-based company and enjoy sharing our know-how. So you can truly make the most of our products, technology and services. And, perhaps, even better serve your customers. “Better staining. Better diagnostic morphology. Three Ways.” Thursday 18 September 12:30 – 13:15, Meetingroom F2 We look forward to seeing you there. Of course there will be time for a Q&A session afterwards. Sysmex Sverige www.sysmex.se Shaping the Advancement of Healthcare * So why not take some time out from your busy schedule to brush up on some of our latest insights and enjoy a tasty lunch? We think you’ll appreciate it … iPod nano is a trademark of Apple Inc. This year at the XXXIV Nordic Congress in Clinical Chemistry, Gothenburg, Sweden, we are holding a lunch symposium – given by one of our experts within Laboratory Solutions. Social Program Welcome Reception Tuesday, September 16th, 15:15 Immediately after the last session this day a Welcome Reception will be held in the exhibition area. The reception is hosted by the City of Göteborg and the Region of Västra Götaland. Participation is included in the congress fee but must be reserved in advance through the online registration system to obtain a ticket. Glitter and Glamour Banquet Thursday, September 18th, 19:30 Estrad Restaurant, Mässans gata 5. Entrance 5 Come and join colleagues and new friends! The Congress Banquet with the theme, “Glitter & Glamour” will be held in the Estrad Restaurant, one of the restaurants in the Congress Centre. We will start with a drink at “Bryggan” located on the first floor, directly above our entrance. We then proceed along the “red carpet” to the ­Estrad Restaurant where a delicious three course dinner will be served. During this evening, the winners of the Astrup prizes and the recipients of the Eldjarn prizes will be announced. The “Glitter Girls” Jamladies will entertain us followed by a Dj and dancing. Participation is not included in the congress fee. Price SEK 700. 26 Jamladies are three well experienced artists who will give your evening that little extra when it comes to glitter and glamour. With fancy costumes, beautiful voices and a warm and charming appeal Jamladies will create a show you will never forget. Congress Information Abstracts All abstracts will be available in an abstract database on the web site www.nfkk2014.se You can search for abstracts in several different ways; browse author index and session programme indices (orals and posters) or free text search. Badge Participants will receive their name badges at the conference registration desk. Since only registered participants will be permitted to attend the scientific sessions, the exhibition and poster areas, you are kindly requested to wear your badge when entering the congress venue. Please note that admission to scientific sessions is strictly restricted to participants wearing their badges. Exhibitors without a full congress registration are not entitled to attend the scientific sessions. Lost badges can be replaced at the registration desk. However, a handling fee will be charged. Cloak room There is an unattended cloak room in the exhibition are. Coffee breaks and luncheon Refreshments will be served free of charge in the exhibition area. Congress Web site In time for the congress we will rearrange www.nfkk2014.se to focus on the information you need when you are on site. The site will also be optimised for portable units to fit nicely on your smartphone or tablet. The Daily News is produced by our editorial on site, follow it on our big screen or on nfkk2014.org On site Registration Registration Desk Opening Hours Tuesday 16th................................................11.00–15.30 Wednesday–Thursday 17th & 18th...........07.30–16.30 Friday 19th...................................................08.00–12.00 On-site registration is accepted but participation in the social events at that time may be severely limited. Exhibition Opening Hours Tuesday 16th................................................11.00–18.00 (Welcome reception 15.15–18.00) Wednesday 17th.........................................09.30–16.30 Thursday 18th.............................................09.30–16.30 Friday 19th...................................................09.30–12.00 27 General Information Credit cards Commonly accepted credit cards in hotels, restaurants and shops and at the conference ­registration desk are American Express, Diners Club, Visa, Master Card and Euro card. Restaurants and shops generally display signs indicating what cards they accept. Currency The local currency is the Krona (pl. kronor). 1 krona = 100 öre. Approximate exchange rate: 1 EUR = 9.15 SEK. Most banks, the manned ones, can exchange foreign currency. Credit cards are widely accepted in Sweden and the exchange rate is usually better than for cash or travellers cheques. It is advisable to find out what the commission is before proceeding with the transaction. Electricity Sweden uses 230-volt AC, 50Hz current. Visitors will need an adaptor for electric appliances, whereas North Americans need a transformer. Emergency numbers For all emergencies, please dial 112. Internet There is WIFI access in the exhibition area. Use the net work NCCC2014 and login NCCC2014 to go on line. Insurance Neither the Conference Organisers or the Conference Secretariat accept any liability for ­personal injuries sustained, or for loss or damage to property belonging to conference participants, either during or as a result of the conference. Language The official conference language is English. There will be no simultaneous translation. Swedish is the official language in Sweden. English is common in hotels and tourist places and is also spoken by most Swedes. 28 Foto: Kjell Holmner Foto: Kjell Holmner Public transportation Gothenburg has a very modern and efficient public transportation network which includes an elaborate tramway system, buses, and ferries. The city has over 200 trams, covering 11 different routes, all of which connect to other forms of transport. Gothenburg also bills itself as having “the world’s most modern public transportation system”, with electronic signs at all tram, bus, and ferry stops telling passengers exactly when the next one is coming and ­notifying riders of any traffic snarls in the system. The information posted on the trams and stops is in Swedish only, so you should have a good idea of how the trip should go before starting. www.vasttrafik.se/en From Landvetter Airport to the Congress Centre Gothenburg-Landvetter Airport – main international airport – is located 20 km to the east of Gothenburg. Airport buses are running frequently between Gothenburg and the airport. Take the airport bus (SEK 90 = approx. EUR 9) or taxi to Korsvägen (SEK 450 = approx. EUR 50) – opposite The Swedish Exhibition Centre´s main entrance. From City Airport (Säve Airport) to the Congress Centre Gothenburg City Airport is located 8 km to the north of Gothenburg. Buses run every 20 ­minutes between the airport and Gothenburg Central Station. Stop at Nils Ericssonsplatsen/ Central Station. Change to tram (see below). The trip takes 35 minutes. A taxi fare between the airport and the City Centre is approximately SEK 400 (around EUR 45). From Gothenburg Train Central Station by tram Take tram No. 4, 13 or 14. From nearby Brunnsparken, you can take tram No. 4 or 5. The trams stop at Korsvägen, just opposite Svenska Mässan and Gothenburg Convention Centre. 29 Foto: Bernstone Fotografi Foto: Kjell Holmner Tram Gothenburg has the largest tram network in Europe. Taking the tram is one of the nicest ways of getting around in Gothenburg. The city has 204 trams which operate 11 routes, as well as buses and archipelago ferries. The Älvsnabben ferry provides services along the harbour. The journeys are included in the same public transport ticket. The easiest way is to buy tickets in advance from Tidpunkten or Pressbyrån shops. The Gothenburg’s City Pass, available from all tobacconists allows unlimited use of the city’s excellent tram and bus system. You can also buy your ticket directly on the bus or tram. Shopping Department stores and most shops are open from: Monday–Friday....................................... 09:30–18:00 Saturday.........................................09:30–13:00/16:00 Sunday (department stores)....................12:00–16:00 In Sweden, many convenience stores (“närbutiker”) are open 07:00–23:00 in major cities, such as Stockholm, Gothenburg and Malmö. 30 Foto: Kjell Holmner Foto: Lars Ardarve Taxis The concierge of your hotel can call a taxi for you, or you may want to call the following taxi companies: “Taxi Göteborg”: +46 (0)31 650 000 or “Taxikedjan” +46 (0)911-922 66. Gothenburg’s taxis are one way of getting around in the city, although the meter ticks away alarmingly when you are stuck in the rush hour traffic. You can share the front seat with the driver if you wish. There is an initial charge when starting the journey. There is a slightly higher rate per ­kilometre if leaving the city limits. If you pay by credit card, it is necessary to inform the driver in advance. Note! There are a lot of so called “Svart taxis” in Gothenburg. That means a person ­driving an ordinary car without a taxi license. Usually they come up to you asking you if you would like a “Svart taxi”. We do not recommend you to take these taxis. Smoking policy No smoking will be permitted at any time inside the conference venue. Smoking is banned on public transport, in stores, restaurants and pubs. Hotels offer special rooms for non smokers. Please indicate your request on the registration form, when you make your hotel reservation. Time zone Sweden is one hour ahead of Greenwich Mean Time (GMT). 31 Foto: Bernstone Fotografi Foto: Jorma Valkonen Tourist information For tourist information about Gothenburg, Sweden, please visit the website: ­ www.goteborg.com. VAT The standard VAT rate in Sweden is 25%. Everybody who visits Sweden as a tourist and who is not a resident of an EU country is eligible for the VAT reimbursement (More information at www.globalrefund.com). Note that value added tax in Sweden is almost always included in the price that is ­ indicated in shops. Visitors from outside the European Union are able to reclaim the VAT on goods purchased, either at the airport or at the border. Look for the tax-free sign in shops and please remember to ask for the VAT reclaim form at the time of the purchase. Global Refund Sverige has around 15’000 affiliated shops and department stores. Minimum purchase is 200 SEK. When ­purchasing the goods, a Global Refund Cheque is issued and your items are sealed. The Global Refund Cheque can be cashed upon departure from the EU at any exit point – ports, ferry t­ erminals, airports, border crossings, etc. The cheque is valid during the month of ­purchase and during the 3 following months. For additional information, please contact: Global Refund Sverige E-mail: taxfree@se.globalrefund.com Venue Svenska Mässan (The Swedish Exhibition & Congress Centre) in Gothenburg Visitor´s addresse: Mässans Gata 2, Entrance 2. 32 2014H-017A Today’s well-being is tomorrow’s greatest resource. Siemens answers are creating an impact on human health that will last generations. siemens.se/healthcare The healthier people are today, the better the world will be tomorrow. That’s because long, healthy lives make it possible for people to give their best. And build a happier world for today’s generations and generations to come. That’s why Siemens works to advance human health, with answers that last. We’re helping clinicians and hospitals expand access to care while cutting costs, so they can better care for a growing world. We’re creating innovations that will have a lasting impact, so an aging population can continue to be a healthy one. We believe that, like every precious resource on earth, human health should be cherished, sustained. Not just for today, but for the promise of a better tomorrow. Answers for life. Our Exhibitors Exhibitor Stand No Abbott Scandinavia AB ACC NordiC AB Alere AB AH diagnostics Beckman Coulter AB Bio-Medical Lab Supplies Ltd Bio-Rad Laboratories AB BioMerieux Sweden AB Biotech-IgG AB Exhibitor 12 23 32 22 10 5 3 27 25 Entrance 1 BP F2 F3 TECH 260 seats TECH buffét buffét posters Gång BP Triolab 34 posters Fiomi 33 TECH 250 seats Cloakroom Passage to Gothia Towers/ Meeting Rooms 34 26 6 4 24 7 40 8 29 33 Slide Room Press Room 36 F1 Room Nordenskiöld Stand No CALPRO AS CellaVision CompuGroup Medical Lab AB Dako DiaSorin AB DiaSystem Scandinavia AB Electra-Box Diagnostica AB Euro Diagnostica AB Fiomi Diagnostics AB Tieto 28 Buffét Roche Diagnostics 13 Siemens Healthcare Diagnostics 9 Nordic Alere BioSite 30 32 Scantec 39 DiaSystem 40 LGC 37 HaemoMedtech 38 Electra 8 DiaSorin 7 CellaVision 6 Bio-Medical 5 Staff/Storage 35 Stand No Nordic Haenostatis 41 Sysmex Sverige 14 Buffét Thermo Fisher Scientific 11 Beckman Coulter 10 SERO 19 GATC Biotech AB 17 Haemo Medtec Aps 38 HemoCue 15 IDS Nordic A/S 20 Lab-Tech & Skafte Medlab 1 LGC37 Merck Millipore 21 Nordic BioSite 30 Nordic Haemostasis AB 41 Roche Diagnostics 13 Timedico 18 GATC Biotec 17 Euro Diagnostica 29 HemoCue Abbot 15 Scandinavia AB 12 Compu Group 4 Registration IDS Nordic 20 Bio Rad 3 Buffét Lab-Tech Software 1 Point 2 550 platser daily news Millipore 21 AH Diagnostics 22 ACC Nordic 23 DAKO 24 Biotech 25 CALPRO 26 bioMérieux 27 Exhibitor Exhibitor Scantec Nordic AB SERO AS Siemens Healthcare Diagnostics Software Point Sysmex Sverige Thermo Fisher Scientific Tieto Sweden Healthcare & Welfare Timedico A/S Triolab AB Stand No 39 19 9 2 14 11 28 18 34 Entrance 2 35 Foto: Dick Gillberg Foto: Krister Engström Foto: Liseberg Operan Kajskjul 8 Göteborg Lilla Bommen Central Station Ullevi city Scandic Hotel Opalen n ny e Av The Swedish Exhibition & Congress Centre Götaplatsen Museum of Modern Art Villa Fridolin Hotel Gothia Korsvägen Universeum Thanks to our Sponsors and Exhibitors P latinum sponsors: ARING OUR E – JOIN US! G old sponsor S: er diagnostic morphology. Three Ways.” E xhibitors: ACC NordiC AB, Alere AB, AH diagnostics, Bio-Medical Lab Supplies Ltd, Bio-Rad ­Laboratories AB, BioMerieux Sweden AB, Biotech-IgG AB, CALPRO AS, CellaVision, CompuGroup Medical Lab AB, Dako, DiaSorin AB, DiaSystem Scandinavia AB, Electra-Box Diagnostica AB, Euro Diagnostica AB, Fiomi Diagnostics AB, GATC, HaemoMedtec ApS, IDS Nordic A/S, Lab-Tech & Skafte Medlab, LGC, Merck Millipore, Come visit us Nordic Biosite, Nordic Haemostasis AB, Scantec Nordic AB, SERO AS, Software Point, booth Tieto Sweden Healthcare & Welfare, Timedicoat A/S, Triolab#14 AB and win an iPod nano* ! Samtliga foton genom Mediabank Göteborg & Co – 13:15, Meetingroom F2