MEDICAL GASES Manufacture, Storage, Transport + Delivery First Year Respiratory Therapy MJC RsCr 220 Composition of the Air We breathe earth’s atmosphere composed of: Nitrogen (78%) Oxygen (21%) Carbon Dioxide (0.03%) Argon and trace gases (0.93%) Neon, Xenon, Krypton and Deon RsCr 220 2 How Oxygen is produced Fractional Distillation Physical Separation Nitrogen Molecular sieve Semi-Permeable membrane Fractional Distillation Large Manufacturing Facility Fractional Distillation for liquid O2 RsCr 220 5 Fractional Distillation Atmospheric air is filtered of pollutants, carbon dioxide and water Air is compressed and cooled to a liquid Then it is slowly heated and the nitrogen boils off. Liquid oxygen remains RsCr 220 6 Physical Separation Molecular Sieve Semi-Permeable Plastic Membrane (in the home) Molecular Sieve Composed of inorganic sodium aluminum silicate pellets These pellets absorb the nitrogen and water vapor from the air Produces up to 90% mixture RsCr 220 8 Oxygen Concentrator RsCr 220 9 Semipermeable Membrane Pulls air through membrane Oxygen passes through faster than nitrogen Can produce 40% mixture Good for long-term low flow oxygen RsCr 220 10 Oxygen concentrator–Semi-permeable membrane RsCr 220 11 Physical Separators Will produce concentrations for nasal cannula but only at low flows Used in oxygen concentrators IN THE HOME RsCr 220 12 Home Concentrator RsCr 220 13 Medical Gases Oxygen, Carbon Dioxide, Helium, Nitrous Oxide, Nitric Oxide, Nitrogen, Carbon Monoxide Properties of Common Gases Chemical symbol Molecular weight Color, odor, taste Physical state Critical temperature, boiling point Combustion characteristics RsCr 220 15 Oxygen 02 Molecular Weight 32 Colorless, odorless, tasteless Slightly heavier than air Density of 1.29 g/L Nonflammable but supports combustion RsCr 220 16 Compressed Air Is the same mixture of nitrogen, oxygen, carbon dioxide and argon. Is piped in to all modern hospitals Used to power pneumatically powered equipment Some situations (patients are C02 retainers) when oxygen is contraindicated RsCr 220 17 Carbon Dioxide C02 Colorless and Odorless Does not support combustion More soluble in liquids than oxygen Used in fire extinguishers Easier transporting in blood then oxygen Used to treat hiccups (singulation) RsCr 220 18 Helium He Odorless, tasteless, non-flammable Second lightest of gases Combined with oxygen (heliox) to reduce work of breathing with swollen upper airways RsCr 220 19 Nitrous Oxide N 20 Nonflammable but supports combustion Used as an anesthesia in OR (laughing gas) Always mixed with oxygen (Entonox) and other anesthesia agents RsCr 220 20 Nitric Oxide N0 Is nonflammable but supports combustion Used experimentally in low concentrations (ppm) for pulmonary vasodilation Recently has had excellent results with premature babies RsCr 220 21 Nitrogen N2 Used as lab gas (liquid) for freezing tissue RsCr 220 22 Carbon Monoxide CO Used in Pulmonary Function Lab Very diffusible – used to test how easily gas will pass through the lung membranes RsCr 220 23 Cyclopropane Strictly an anesthesia gas RsCr 220 24 Ethylene Oxide Used to gas sterilize medical equipment Useful for equipment that can’t handle high temperatures or immersion in water RsCr 220 25 Oxygen Storage Tanks – Liquid Tanks - Gas Tank Sizes and Capacities Large Cylinders Small Cylinders Oxygen Tank Sizes RsCr 220 28 H Cylinders 2200 psi A.S.S.S safety system Threaded connection Need to be safety chained and in a secured dolly for moving RsCr 220 29 E Cylinders Small and lightweight (15 pounds) PISS – Pin Index Yoke connection RsCr 220 30 Types and colors of cylinders Air Yellow Oxygen Green – Int’l (White) Helium Brown CO2 Grey Nitrogen Black Nitrous Oxide-Blue Do NOT trust the color of the tank as sole indicator of it’s contents RsCr 220 31 Labels – The only sure way RsCr 220 32 Other Oxygen Tank Markings RsCr 220 33 Regulation of cylinders D.O.T O.S.H.A. F.D.A. B.M.D. Recommending Agencies C.G.A. N.F. P.A. A.N.S.I. I.S.O RsCr 220 35 Bulk Supply Systems Liquid Oxygen Bulk Oxygen Systems Large capacity Liquid oxygen Small system (or back up) Nitrous Oxide Bank of H cylinders RsCr 220 37 Large Oxygen Supply System RsCr 220 38 Small Bank of Cylinders RsCr 220 39 Liquid vs Gas Insulated – Liquid Solid metal - Gas Large continuous demand – Liquid Small portable – Liquid or tank Tanks act differently if they contain gas or liquid No accurate gauge on liquid tank content RsCr 220 40 Go figure RsCr 220 41 Liquid Oxygen Constantly losing oxygen despite insulation Needs pressure and insulation for cold temperature (-118oC) Low pressure (200 psi) Large system has vaporizers fins to help with heat transfer when liquid turns to gas (frozen year round) Small system is great for mall shopping RsCr 220 42 Bulk Liquid Oxygen supply RsCr 220 43 Bulk Oxygen Supply System RsCr 220 44 Home Liquid Oxygen RsCr 220 45 Low Pressure Safety Systems Diameter Index Safety System Quick Connect Wall (low pressure) systems D.I.S.S. 50 P.S.I The MJC lab has these Quick connect A newer “better system” RsCr 220 47 DISS (and Dat) RsCr 220 48 DISS Wall Outlet RsCr 220 49 Different Quick Connects RsCr 220 50 More Quick Connects RsCr 220 51 Flowmeters Thorpe Tube is most common Can use Bourdon Gauge RsCr 220 52 RsCr 220 53 Other Safety Features Zone Valves Zone Valve System RsCr 220 55 Zone Valves for bulk O2 supply RsCr 220 56 Cylinder Connections (High Pressure) American Standard Safety System Pin Index Safety System Key Index Safety System Regulators They decrease internal tank pressure down to a working pressure (50psi) They read and display the internal tank pressure They meter out the precise flow for patient use. RsCr 220 58 Cylinder connections A.S.S.S. (American Standard) H cylinders High pressure, large tanks P.I.S.S. (Pin Index) E cylinders High pressure, small tanks RsCr 220 59 American Safety Standard System RsCr 220 60 Pin Index System RsCr 220 61 Pin Index System RsCr 220 62 Pin Index Numbering for small cylinders RsCr 220 63 Tank Duration How long will they last Cylinder Duration Calculations You can memorize size of tank then calculate how long it will last Or use: Conversion factors 3.14 for H cylinders 0.28 for E cylinders RsCr 220 65 Liquid Oxygen Duration Convert pounds to liters Multiply by 860 to get volume of gaseous oxygen (Liters) Divide by the liter flow (L/min) Convert minutes to hours and minutes RsCr 220 66 Thanks for listening RsCr 220 67