NuPECC – Long Range Plan 2010 Working Group 6 Nuclear Physics Tools and Applications J. Benlliure (Univ. Santiago de Compostela), A. Boston (University of Liverpool), M. Durante ( GSI Darmstadt), S. Gammino (INFN-LNS Catania), J. Gomez Camacho (CNA, Sevilla), M. Huyse (K. U. Leuven), J. Kucera (Nuclear Physics Institute, Rez), S. Leray (CEA/Irfu) (Convener), L. Sihver (Chalmers University), C. Trautmann (GSI Darmstadt) NuPECC: Ph. Chomaz (CEA/Irfu) (SC), E. Nappi (INFN-Bari) (liaison), With contributions from : A. Aloisio (Università and INFN Napoli), M. Caccia (Università dell’Insubria and INFN Milano), F. Javier Santos (CNA Sevilla), A. Letourneau (CEA/Irfu), P.A. Mandò (INFN Florence), G. Pappalardo (INFN-LNS), P. Pelican (Lubljana), M.A. Respaldiza (CNA, Sevilla), F.P. Romano (INFN-LNS), J.C. Sublet (Culham Centre, UK), M. Toulemonde (CIMAP, Caen), C. Vockenhuber (ETH, Zurich), M. Winter (IRES, Strasbourg) 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 1 Importance of NP applications From the beginning of its history, nuclear physics always closely tied to applications, in particular energy and medicine Marie Curie and her daughter Irène at the Hoogstade Hospital in Belgium, 1915. Copyright © Association Curie Joliot-Curie The Birth of the Atomic Age was captured by Gary Sheahan to remember Enrico Fermi, Chicago Pile-1 and the first sustained nuclear chain reaction. Used with permission of the Chicago Historical Society. Today, both renewed interest for certain applications and new opportunities provided by advanced NP tools and techniques 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 2 Domains of applications Nuclear energy Life science and radioprotection Environmental and space applications Security Applications in material science and other fundamental domains Cultural heritage, arts and archaeology New frontiers in NP tools (accelerators, detectors, microelectronics) 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 3 Nuclear energy • Revival of nuclear energy (due to increase in energy demand, need for CO2-free energies) Advanced options for nuclear energy generation Next generation fission reactors (Gen-IV) inherent safety sustainability economics proliferation resistance MYRRHA Accelerator-driven sub-critical reactors Transmutation of nuclear waste in dedicated systems Demonstrator (MYRRHA) IFMIF Accelerator Fusion reactors ITER, DEMO Material test facility (IFMIF) 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - D+ Beam (40 MeV, 2x 125 mA) Li Target Li Free Surface Test Cell Neutrons (~1017n/s) 10 MW Specimens EMP 4 Nuclear energy • The role of nuclear physics for accurate nuclear 232 Th(n,) bdf photons dif fus és bdf radioactiv ité dn/d(lnE) coups par bunch need 103 102 data for: – Existing reactors (increase of fuel burnup, life time…) – Fast reactors (GenIV) (new materials) – ADS (actinide transmutation, HE data…) – Fusion reactors (activation data, (n,xn) for n multiplication, tritium breeding….) 101 100 100 101 102 103 104 105 106 energie de neutron (eV ) Nuclear data and models – Measurements of cross-sections, characteristics of reaction products, nuclear structure data …. – Reaction models for libraries, transport codes – Integral experiments 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 5 Nuclear energy • The role of nuclear physics Methods and tools developed nuclear physics for – High-power accelerators, d-t sources…. – Advanced detector systems, electronics, modern data analysis techniques n_TOF BaF2 calorimeter important infrastructures: – n-ToF (CERN) 2nd phase with the construction of the short flight path – NFS at SPIRAL2 especially for fusion relevant data – FAIR/NUSTAR: DESPEC-MATS for structure data, R3B-ELISE for reaction studies – HIE-ISOLDE, GANIL for surrogate reactions studies Education, training and know-how preservation 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 6 Nuclear energy • Recommendations Support to small scale facilities and unique installations Fundamental studies should be encouraged Effort on evaluation should be increased and involvement of theoreticians in nuclear reaction models development should be encouraged so that European measurements contribute to European libraries and transport codes Improvement of the relations between fundamental physicists, reactor physicists, theoreticians, evaluators and end-users (networking) Coordinated European action for radioactive target production and handling 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 7 Life science • Increasing use of nuclear physics tools in medicine, both in diagnostics and therapy Radioisotope production Particle therapy Imaging Radioprotection/radiobiology 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 8 Life science Radioisotope production – 99Mo/99mTc supply and alternative methods for 99Mo production – β+ emitters, metal radionuclides for PET imaging – Production in-situ of short lived isotopes – radiotracers in drug development role of nuclear physics – Production of novel radioisotopes: reaction cross-sections, improved production techniques using e.g. new radiochemistry schemes, targets sustaining high intensities… – The very high sensitivity of AMS for 14C detection permits studies of the metabolism and kinetics of substances labeled with very small quantities of 14C 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 9 Life science Particle therapy – Many proton centers now operating in the world, more in preparation – Development of carbon therapy: Heidelberg (Germany); projects: ETOILE (France), CNAO (Italy), MedAustron (Austria) role of nuclear physics – Precise nuclear data, in particular concerning the fragmentation process (C and others) – Appropriate nuclear models and libraries to be used in treatment planning codes – Development of cheaper and more compact accelerators (e.g. plasma-based ) 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 10 Life science Imaging – Macroscopic imaging systems providing anatomical and physiological information: CT, MRI…. – Systems providing molecular, functional information: PET, SPECT… role of nuclear physics – High sensitivity detectors (dose reduction) – In beam PET and SPECT for monitoring of the dose deposition), combination of several techniques (PET-CT, SPECT-MRI, PET-MRI…) – ToF techniques to allow real-time observation of the dose delivery, reconstruction-visualisation algorithms 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 11 Life science Radioprotection/radiobiology – Accurate assessment of doses received during medical treatment (and more generally after some exposition) – Understanding of low dose effects: bystander/abscopal effects (effects in cells/organs not directly exposed), hormesis (low doses protect from high dose exposure)… role of nuclear physics – Nuclear data and reaction models – Nuclear physics tools (accelerators, isotope labeling, high sensitivity detectors, underground laboratories….) for radiobiology studies 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 12 Life science • Recommendations Access to beam time and adequate equipment at NP facilities should be guarantied Links between fundamental (physics and biology), applied research and medical centers should be reinforced Research in life science applications helps improve the perception of NP 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 13 Environmental and space applications • Nuclear physics tools play an important role in environmental applications Climate evolution: measurements of some radioactive or stable nuclides – studies of paleoclimate, ocean circulation (129I) – CO2 exchange between atmosphere and ocean (14C) – 10Be and 26Al with AMS for estimation of the age and origin of sediments Water and food management – dating, tracing and source identification for water resource management, understanding of water cycle – Sterilization, techniques plant breeding using mutation Pollution control – Tracing of contaminant in air, water… 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 14 Environmental and space applications • Space applications Radiation hazard in space – Assessing radiation risk of astronauts on low earth orbits (ISS, space shuttle) or on mission to the Moon or Mars due to Solar Particle Events and Galactic Cosmic Rays – Radiation damage to electronics (single-event upset) Simulation codes for radiation risk assessment – Measurement of relevant data (p to Fe induced reactions) – Development of nuclear reaction models Nuclear power sources for satellites and spacecrafts 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 15 Environmental and space applications • Recommendations profit from the strong interest in climate change studies to (re)-build highly trained teams, in particular in AMS techniques support to cross-disciplinary projects 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 16 Security • Nuclear physics methods (both passive and active) for security applications Detection of concealed fissionable or other radioactive material in airports, ship containers, trucks…. – Neutron/photon interrogation techniques – detection of gammas, neutrons, delayed or prompt identification of Special Nuclear Material: Pu, HEU (235U), 233U and 237Np and suspicious radionuclides that may be associated with: 232U, 238U, 241Am but also of isotopes used in medical or industrial applications Detection of explosives – technology based on neutron bombardment would allow identifying the elemental composition of items packed in hold luggage 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 17 Security challenges: – high intensity portable neutron generator, – improved spectroscopic gamma-ray scintillators, e.g. medium energy resolution material such as cadmium zinc telluride (CZT) and LaBr3 for Eγ up to 3MeV, Ge using gamma tracking for location of isotopes – development of improved non flammable neutron scintillators with digital neutron/gamma separation – Nuclear data (photonuclear reactions, delayed n and γ) 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 18 Security • Nuclear physics methods for security applications Non-proliferation control – Measuring traces of nuclear materials with AMS, γ-spectrometry (also for accidental comtamination) High sensitivity detection methods – Use of anti-neutrinos to control possible illicit use of reactors (neutrino spectrum sensitive to the composition of the fuel (Pu/U)) Depends on the achievable precision on fission products yields, β-decay Scheme of the Nucifer detector 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 19 Security • Recommendations Further mechanisms need to be established : – to encourage knowledge transfer between academic nuclear community and industry – to protect the investment in training the younger generation through graduated and post graduate programmes 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 20 Applications in material science and other fundamental domains • Availability of ion beams of all elements (stable and radioactive), from KeV to hundreds of GeVs and advanced detection techniques new opportunities in materials science, nanotechnology, planetary and geosciences, plasma physics… – Understanding and characterization of material properties – Controlled modification and nanostructuring of materials 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 21 Applications in material science and other fundamental domains • Ion beam analysis and modification with lowenergy beams (< MeV) characterization of structure properties (ordering, occurrence of defects….) analysis of electrical, magnetic and optical functionalities properties can be controlled or modified by ion implantation Layers can be grown leading to new properties at interfaces and surface design of hybrid materials e.g. with magnetic and superconducting properties 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 22 Applications in material science and other fundamental domains • Ion beam analysis and modification with low-energy beams (< MeV) Using stable ions – Nuclear reactions for depth profiling or to analyze light element concentrations – Proton induced x- and γ-emission, non-destructive method with a detection limit ~ 100 ppm Using radioactive ions (at ISOL facilities e.g. ISOLDE) – Dynamical properties studied by recording decay of implanted radioactivity – Emission channeling: direction of emission sensitive to crystal structure Low E, low I universities, small institutes 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 23 Applications in material science and other fundamental domains • Material modification with high-energy heavy-ions beams (MeV-GeV) Material structuring – adjusting the structuring depth via beam energy, writing structures with microbeams, placing individual ions at defined positions – ion tracks with MeV-GeV HI produces nanopores in membranes (commercial filters, cell cultivation substrates, synthesis of nanowires) Tracks of 100 MeV oxygen ions from linewise (upper pictures) and matrix irradiation 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - Ion-beam produced nanostructures 24 Applications in material science and other fundamental domains • Material modification with high-energy heavy-ions beams (MeV-GeV) Materials exposed to radiation – Characterization and control of material exposed to extreme radiation environments (high-power accelerators, fission and fusion reactors) – response of solids simultaneously exposed to several extreme conditions such as high pressure, temperature, and HE beams – exposure to HE ion beams and high pressure important in geosciences (stability of planetary and geomaterials, understanding processes in the Earth’s interior) Samples pressurized between two diamond anvils up to several tens of GPa irradiated with relativistic heavy ions of sufficient kinetic energy to pass through several mm of diamond. 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 25 Applications in material science and other fundamental domains • Recommendations fundamental understanding needed to go beyond today’s “cook and look” approach promising trends that should be further promoted providing suitable beams and warranting sufficiently frequent access to nuclear-physics dominated facilities favour closer interlink between the existing complementary facilities within Europe (e.g. FP6 ITS LEIF, FP7 SPIRIT) 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 26 Cultural heritage, arts and archaeology • Extensive use of nuclear physics tools (virtually nondestructive) to obtain information of archaeological and artistic objects : in-depth elemental analysis dating Ion beam analysis techniques (IBA) mainly at AGLAE (Louvre) and LABEC (Florence) 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - PONT44 - c118v 500 S+Pb(M) 400 Counts – external PIXE (Particle-Induced X-ray Emission) – PIGE (Particle-Induced Gamma-Ray Emission) – high energy resolution detectors. – Recent developments aiming at determining the depth profile of the sample : confocal PIXE, differential PIXE, deep proton activation analysis Ca Al 300 200 100 Na Si P K Cl 0 0 2 4 6 8 10 12 Energy (keV) 27 Cultural heritage, arts and archaeology Neutron activation techniques – Advantages: deep penetration, selective resonant absorption for specific elements – Thermal and epithermal beams at some reactors, ISIS, ESS in the future – Neutron Resonant Capture Imaging combined with Neutron Resonance Transmission as a non-invasive technique for 3D tomographic imaging AMS techniques – Dating with 14C (new simpler, more compact and cheaper generation developed at ETH Zurich using multiple ion collisions to destroy molecular interference) • Recommendations A European network of AMS facilities exchange of information between the different fields 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 28 New frontiers in Nuclear Physics tools • Accelerators High-power accelerators – Synergies between fondamental research (SPIRAL2, EURISOL) and applications: ADS (MYRRHA), spallation sources (ESS), IFMIF… Planned IFMIF facility – Already a large European effort – Further research needed in : fast cycling magnets, beam cooling devices, highly charged ion sources, high power targets, superconducting cavities – Questions about reliability, beam losses still need to be solved 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 29 New frontiers in Nuclear Physics tools • Accelerators Plasma-based accelerators – May revolutionize the field leading to much cheaper and compact systems for instance for hadrontherapy – Technology not yet mature, questions about achievable intensities, beam qualities… Magnets – R&D on magnets for accelerators useful for different industrial and medical application, in particular for NMR applications – To reduce cost, research on high Tc superconducting materials necessary (e.g. V3Si) 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - One of the first Silicon Photomultipliers (SiPM) produced by IRST (Trento, Italy) Iseult magnet (11.7 T) for NEUROPSIN 30 New frontiers in Nuclear Physics tools • Detectors Advanced γ-ray spectrometers (γ tracking) – Security, medical applications Micro-pattern gas detectors (Micromegas, GEM) – High spatial resolution, large area – High rate capabilities, radiation hardness Direct beam imaging of a 1.2 MeV proton beam obtained in Namur, with a CMOS pixel detector 3D silicon strip detectors – Very short collection time, radiation hardness Monolithic active pixel sensors – granularity and spatial resolution at the micron level – ultra-low material budget Principle of GEM detector Silicon photomultipliers – Possibility of detecting single photons – expected time resolution at the 100 ps level new perspectives in different applications, in particular medical imaging 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - One of the first Silicon Photomultipliers (SiPM) produced by IRST (Trento, Italy) 31 New frontiers in Nuclear Physics tools • Electronics analogical – Si-Ge and Silicon-on-Insulator (SOI) VLSI technologies – SOI appealing for the design of monolithic active pixel sensors (MAPS) detectors digital – Last generation FPGAs for transfer of data streams at rates up to 10 Gbit/s – perform sophisticated analysis in every node of complicated systems FPGA from Xilinx FAMMAS (CEA/Saclay) 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 32 New frontiers in Nuclear Physics tools • Recommendations common European R&D platforms for accelerators and detectors Research on new materials for high Tc superconductors should be continued Research for high-power accelerators: ion sources, beam dynamics, reliability… availability and reliability of low noise and low power electronics 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 33 Summary NP finds increasing interest in a large number of interdisciplinary fields likely expansion of nuclear energy in the future, issue of nuclear waste management and perspective of fusion development of particle therapy, need for more sensitive imaging techniques for both diagnostics and therapy and necessity of finding new ways to produce radiopharmaceutical isotopes NP tools extensively used in climate evolution studies and water resource management, and in archaeology and cultural heritage applications NP involved in assessing radiation hazard in space and in the growing field of security related applications and nonproliferation control. 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 34 Summary Progress in Nuclear Physics tools Recent sensitivity improvement of the AMS technique has allowed new progress in nearly all the domains of applications availability of ion beams of elements (stable and radioactive), from KeV to hundreds of GeV, and advanced detection techniques provide new opportunities in materials science, nanotechnology, planetary and geosciences, plasma physic The field of high-intensity accelerators largely benefits from the synergies between studies for radioactive beam production, ADS, IFMIF, radiopharmaceutical isotope production, and ESS. Research on plasma-based accelerators could lead to the development of much more compact and cheaper machines allowing a larger spreading of hadrontherapy Progress in detector development offers very promising opportunities in a lot of interdisciplinary domains, in particular medical imaging 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 35 General recommendations Numerous applications need more accurate nuclear data and reaction models in order to complement European data libraries and/or computer codes necessity to perform fundamental studies response to end-user requests substantial effort should be put on the evaluation process so that measurements can end up rapidly into European data libraries Measurements of nuclear data and material research requires targets or samples of high isotopic purity, which may be radioactive Coordination of target production facilities, situation of radiochemistry, and standardized procedures should be given sufficient attention and addressed at the European level 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 36 General recommendations Small scale facilities as well as installations at large scale facilities are unique within Europe the support for these application oriented activities should be enforced beam time quota for applied research and/or dedicated Program Advisory Committees should be considered to keep the European cutting-edge position it is strongly recommended to closer interlink the existing complementary equipments and facilities. Networking between fundamental physicists and end-users, networks of infrastructures (IBA, AMS or high-energy irradiation facilities), communication with medical doctors, climate scientists, environmental scientists, archaeologists) transfer of trained people to nuclear industry, medical centres, applied research organizations or governmental bodies (as radioprotection and safety authorities) 01/06/10 CEA DSM Irfu - Sylvie Leray - NuPECC LRP2010 WG6 - 37