Vocabulary The Cell Cycle Mitosis Mitosis Cell Cycle Regulation 10 10 10 10 10 20 20 20 20 20 30 30 30 30 30 40 40 40 40 40 50 50 50 50 50 Question 1 - 10 • This is the process by which a cell divides into 2 daughter cells. Answer 1 – 10 • What is cell division? Question 1 - 20 • Collectively, this part of the cell cycle includes the G1, S and G2 phases. They are the “intermediate” phases between periods of cell division. Answer 1 – 20 • What is interphase? Question 1 - 30 • When chromosomes replicate, they form these. It looks like an “x” shape. Answer 1 – 30 • What are sister chromatids? Question 1 - 40 • This is the area where sister chromatids attach. When the spindle forms, this is the part of the sister chromatids that binds to the spindle. Answer 1 – 40 • What is the centromere? Question 1 - 50 • This is a protein that regulates the timing of the cell cycle. Answer 1 – 50 • What is a cyclin? Question 2 - 10 • The cell cycle consists of this many phases? Answer 2 – 10 • What are four? Question 2 - 20 • Cell division occurs in the M phase of the cell cycle. It is made up of these two parts? Answer 2 – 20 • What are mitosis and cytokinesis? Question 2 - 30 • These two phases of the cell cycle control the growth of cells, in between periods of division. Answer 2 – 30 • What are the G1 ad G2 phases? Question 2 - 40 • These are the phases of the cell cycle, in order. Answer 2 – 40 • What are M, G1, S and G2? Question 2 - 50 • Chromosome replication occurs during this phase of the cell cycle. Answer 2 – 50 • What is the S phase? Question 3 - 10 • Mitosis is the division of the nucleus. This is the division of the cytoplasm. Answer 3 – 10 • What is cytokinesis? Question 3 - 20 • Mitosis occurs during this phase of the cell cycle. Answer 3 – 20 • What is M phase? Question 3 - 30 • This is the longest phase of mitosis. Chromosomes condense, the nuclear envelope disappears and the centrioles form a spindle across the cell. Answer 3 – 30 • What is prophase? Question 3 - 40 • During this phase, the sister chromatids split, becoming two individual chromosomes. They begin to move to opposite ends of the cell. Answer 3 – 40 • What is anaphase? Question 3 - 50 • Cytokinesis usually happens at the same time as this phase of mitosis Answer 3 – 50 • What is telophase? Question 4 - 10 • Cytokinesis is the division of the cytoplasm. This is the division of the nucleus. Answer 4 – 10 • What is mitosis? Question 4 - 20 • This is the acronym for the four phases of mitosis. Answer 4 – 20 • What is PMAT? Question 4 - 30 • During this phase, the sister chromatids line up across the center of the cell and their centromeres attach to the spindle. Answer 4 – 30 • What is metaphase? Question 4 - 40 • During this phase, the spindle disappears nuclear envelopes re-form around the two new sets of chromosomes. Answer 4 – 40 • What is telophase? Question 4 - 50 • During cytokinesis, animal cell membranes simply draw in and pinch off, creating two new cells. However, in plant cells, this structure forms as a precursor to the cell wall. Answer 4 – 50 • What is the cell plate? Question 5 - 10 • Uncontrolled cell growth can cause this disease? Answer 5 – 10 • What is cancer? Question 5 - 20 • This is a form of cancer treatment where toxic chemicals are used to alter the cell cycle of cancerous cells. Answer 5 – 20 • What is chemotherapy? Question 5 - 30 • There are two types of cyclin drugs. Internal regulators respond to events inside the cell while these respond to signals outside the cell. Answer 5 – 30 • What are external regulators? Question 5 - 40 • When functioning properly, this gene is in charge of pausing cell division until all DNA is properly copied. Answer 5 – 40 • What is the p53 gene? Question 5 - 50 • Cyclins are a family of proteins that regulate the timing of the cell cycle. When injected into non-dividing cells, the cells will then do this Answer 5 – 50 • What is divide?