Djaudat Idiyatullin*, Steven Suddarth+, Curt Corum*, Gregor Adriany*, Michael Garwood* *Center for Magnetic Resonance Research and Department of Radiology University of Minnesota Medical School, Minneapolis, Minnesota, USA +Agilent Technologies Santa Clara, California, USA ISMRM, 2011 Declaration of Relevant Financial Interests or Relationships Speaker Name: Idiyatullin Djaudat I have the following conflict of interest to disclose with regard to the subject matter of this presentation: Company name: Steady State Imaging Type of relationship: sales royalty and consulting fee SWeep Imaging with Fourier Transform (SWIFT) Fast and quiet MRI using a swept radiofrequency, D. Idiyatullin, C. Corum, J.-Y. Park, M. Garwood, JMR (2006). Applications: • Molecular imaging, • Dental imaging, • Lung imaging, • Breast cancer, • MSK, • Brain calcification. 1 f G Sensitive to fast relaxing spins Projection method No “echo time” Time shared excitation and acquisition acq p Time shared acquisition, limitations d c = p bw 1 dc - excitation duty cycle - acquisition duty cycle S/N 1 dc bw RFenergy dc S/N p trd 1 dc trdbw trd Q 0 1/ bw bw - acquisition bandwidth trd - coil ring-down time The goal of the project To test SWIFT in continuous mode with Varian/Agilent DirectDrive system & digital receiver. 1 f Expected advantages • acquisition duty cycle =1 -> higher S/N; G acq • excitation duty cycle =1 -> lower power & SAR, absence of sidebands; • absence of coil ringing -> SWIFT efficiency at higher bandwidth, with low Larmor frequency (low field, X-nuclear). Could we acquire a signal when transmitter is “on”? 100 9.0909 4T, Breast coil, water phantom cSWIFT, R=256 0.9091 40 db 1 0.0909 Receiver threshold 0.1 0.0091 Volts 1/2 , Hz 10 cSWIFT, R=4096 1 mm MRI signal level 0.01 0.0009 Peak power needed for excitation calculated for: θ = Ernst angle, T1= 1 s with TR=Tacq, bw=50 kHz, R = bwTp Transmitter-receiver isolation Quad coil Tune/Match Hybrid Preamplifier 0 90 90 0 Transmitter Self-duplexing radar technique using circular polarization, ~30- 40 db. Continuous SWIFT spectroscopy Ethanol-water mixture, 4T, bw= 6kHz, 4096 points Chirp cSWIFT signal c exp(i bt ) exp j / 4 b 2 2 S h(t ) c c Ae Transmitter leakage i Smooth function Continuous SWIFT spectroscopy Ethanol-water mixture, 4T, bw= 6kHz, 4096 points MRI signal reconstruction Frequency sweep & time h ( t ) c c Ae i Re Im h ( t ) c c h(t ) c H ( ) F h(t ) c F (c ) 62.5kHz Wow, it is working! Continuous SWIFT 4 Tesla bw= 62 kHz FOV=40 cm 4 minutes 10 Watt amplifier 0.8Watt Regular SWIFT 31Watt Continuous SWIFT imaging Continuous SWIFT Regular SWIFT bone cartilage 0.02Watt 2Watt Human total knee arthroplasty sample, 9.4 Tesla, bw=71 kHz, 128000 views, 7 minutes, without a transmitter’s amplifier. Conclusions • Continuous SWIFT up to 70kHz bandwidth can run in modern MRI scanners without hardware modification. • Challenges: Sensitive to transmitter instability, coil deformations, subject motion, vibrations. Future development: 1. Probe and connection Crossed coils, Hybrids, Circulators 2. Hardware Modulation technique: ωacq =ω0 +ωmod 3. Software Digital Receivers: signal reconstruction, filtering Acknowledgement This research was supported by NIH P41 RR008079, S10 RR023730, S10 RR027290 RR008079, R21 CA139688 grants and WM Keck Foundation. We also thank Jutta Ellermann and Elizabeth Arendt for opportunity to use TKA sample at this study. Thanks