Epidemiology in Italy North, Center, South, Islands 70 National Laboratory Reference for Cystic Echinococcosis -Italia- 60 Sheep 50 Goat 40 Cattle Pigs 30 20 10 Toni Piseddu DVM Istituto Zooprofilattico Sperimentale della Sardegna 0 Nord IX Workshop of NRLs for Parasites Roma, 19-20 maggio 2014 Center South Sicily Sardinia Sinzoo data 2012 Roma, 19-20 maggio 2014 INFORMATION FLOW Presence of Cystic echinococosis in animals in Italy: • The epidemiological situation in the last years should be considered basically constant. • Dangerous situation in Sardinia and Sicily, even if CE prevalence and cyst fertility rates seem to be lower than in the past. The Veterinary Operational Centre for Epidemiology, Programming and Information (COVEPI) • The sheep-dog cycle, especially the role of shepherd dog not managed correctly, is the most important way of diffusion the parasite. Roma, 19-20 maggio 2014 Roma, 19-20 maggio 2014 1 Average prevalence of Human CE in Italian Regions from HDRs 2012 SINZOO: REPORT 2013 7 Regions (Basilicata, Calabria, Molise, Piemonte, Puglia, Valle d’Aosta, Veneto e Sicilia) not sent data for 2013. CASES/100000 INHAB Positivity prevalences trasmitted are ever less than 1% Evident under reporting of animal echinococcosis in Italy Prevalence rate are strongly age dependent and reports from abattoirs that may slaughter only young animals will under represent the real situation Ministry of Health data Roma, 19-20 maggio 2014 Roma, 19-20 maggio 2014 -Presence of Cystic echinococosis in Humans in Italy in 2012 HDRs drawn from the National Ministry of Health • Italy average prevalence rate (A.P.) was 1,51/100.000inhab. • The highest A.P was 3.96/100,000 inhabitants registered in the Islands (2.92 in Sicily and 5.01 in Sardinia) • In the South was registered an A.P. of 2.21 /100,000 inhab. (4.16 in Basilicata) • In the Centre 0.82/100.000 inhab (highest A.P. Latium:1,55) • Prevalence in North was considerably lower, with a registered A.P. of 0.73/100.000 inhab. (1.13 in Emilia Romagna) Roma, 19-20 maggio 2014 2012 Cases Prevalence cases/100000 Islands 228 3.96 Sardegna 82 5.01 Sicilia 146 2.96 South 215 2,21 Basilicata 24 4.16 Molise 8 2.55 Calabria 40 2.04 Puglia 71 1.75 Abruzzo 25 1.91 Campania 47 0.83 Roma, 19-20 maggio 2014 2 2012 Cases Prevalence cases/100000 Centre 215 0.82 Lazio 85 1.55 Umbria 7 0.79 Assisted trasmission of diagnostic Toscana 30 0.82 method: Marche 2 0.13 North 189 0.73 Emilia Romagna 49 1.13 Method CeNRE/02 “IDENTIFICATION OF Echinococcus granulosus COMPLEX AT SPECIES LEVEL FROM HYDATID CYSTS BY PCR” Liguria 13 0.83 Piemonte 31 0.71 Lombardia 53 0.55 Friuli Venezia Giulia 7 0.57 Veneto 28 0.58 Trentino Alto Adige 7 0.68 Valle D'Aosta total 1 0.79 756 1.51 Stage 2013 CeNRE - 6 technicians take part in stage Roma, 19-20 maggio 2014 Roma, 19-20 maggio 2014 PROFICIENCY TEST 2013 CeNRE RING TEST 2013 CeNRE 8 laboratories participating: Method CeNRE/02: - IDENTIFICATION OF Echinococcus granulosus COMPLEX AT SPECIES LEVEL FROM HYDATID CYSTS BY PCR. • Organized on July 2013 and concluded on November 2013 PT targets Armonization, among italian parasitology laboratories, on application of procedure CeNRE/02; • • Identification of possible critical points of procedure; Definition of corrective measures; • Testing preparation, shipment and logistic procedures of reference material for parasitological diagnosis of C.E. from LNR to national laboratories; Roma, 19-20 maggio 2014 - National distribution from north to south, island included. - 8 laboratories received the method and reference materials. - 7 labs were evaluated as “Positive” Partecipant laboratories to PT Roma, 19-20 maggio 2014 3 Training course Cystic and Alveolar echinococcosis: status quo, information flow, regional action planning, lab procedures CeNRE • Update of the disease • Standardize monitoring system and reporting information of data for epidemiological elaboration • Harmonization the interventions of official veterinarians Next editions: Pavia-Perugia Istituto Zooprofilattico Sperimentale della Sardegna Via Duca degli Abruzzi, 8 07100 Sassari mail: cenre@izs.sardegna.it • Doctors • Veterinarians • Biologists Phone number: +390792892325 Fax: +390792892324 • Agronomysts Roma, 19-20 maggio 2014 Roma, 19-20 maggio 2014 4