www.uniprot.org
www.expasy.org
Swiss Institute of Bioinformatics – Geneva in collaboration with the UniProt Consortium
The main focus of the Swiss-Prot group is to provide the scientific community with the most accurate protein sequences associated with a high level of functional annotation, in an user friendly format allowing easy data retrieval and analysis. The group is involved in the production of the manually curated
UniProtKB/Swiss-Prot knowledgebase (www.uniprot.org), the ENZYME nomenclature database (http://www.expasy.org/enzyme) , the protein families and domains PROSITE database (http://www.expasy.org/prosite) and the taxonomy database (http://www.uniprot.org/taxonomy/)
Protein Annotation Programs
- Vertebrates (CD2)
- Bacteria and Archae (HAMAP)
- Plants (PPAP)
- Fungi (FPAP)
- Viruses
- Dictyostelium discoideum
- Drosophila and C.elegans
- Toxins (Tox-Prot)
- Controlled vocabulary (GO annotation)
- Post-translational modifications (PTMs)
- Integration of proteomic data
- Integration of 3D structure information
- Human polymorphisms and diseases
- Quality Assurance
Research
- Calipho
Computer Analysis and Laboratory Investigation of Proteins of Human Origin
- Phylogeny
- Text mining
- Sequence analysis tool development
- Knowledge management of human variants
Software development
- Annotation platform development and maintenance
- UniProtKB/Swiss-Prot release
- ExPASy and UniProt websites
Service, education and popular science
- User support
- Courses and tutorials (e-Proxemis)
- Master in Proteomics and Bioinformatics
- Doctoral school (SIB)
- Protein Spotlight
(www.expasy.org/spotlight/)
- Protéines à la ‘Une’
(www.expasy.org/prolune/)
Electronic publications
Contact
Swiss-Prot group
Swiss Institute of Bioinformatics
Centre Médicale Universitaire
1 Michel Servet
1211 Geneva 4
Phone: + 41 22 379 50 50
Fax: + 41 22 379 58 58 swiss-prot@expasy.org
The team
Amos Bairoch and Lydie Bougueleret
(group leaders)
50 annotators (life science background),
13 programmers, 8 reseachers,
15 persons involved in system administration, service/education and administration.
The Swiss-Prot group is part of the Swiss Institute of Bioinformatics (SIB) and of the UniProt Consortium.
Swiss-Prot group activities are supported by the Swiss Federal Government through the Federal Office of Education and
Science and by the National Institutes of Health (NIH) grant 2 U01 HG02712-04. Additional support comes from the
European Commission contract FELICS (021902RII3) and from the PATRIC BRC (NIH/NIAID contract HHSN
266200400035C).
Swiss Institute of Bioinformatics (SIB)
European Bioinformatics Institute (EMBL-EBI)
Protein Information Resource (PIR) www.uniprot.org