SCHISTOSOMIASIS and OTHER INTESTINAL HELMINTHES SCHISTOSOMIASIS chronic tropical disease Bloodfluke called Schistosoma Japonicum Transmitted through the intermediary host of a tiny snail known as Oncomelania Quadrazi.asi. SCHISTOSOMIASIS: - is one of the most widespread parasitic infection afflicting mankind for a long time (118 years in the Philippines) - second to malaria in Prevalence - rank first in prevalence among waterborne diseases -thrives where environmental sanitation is poor. - eggs hatch into miracidia that penetrate snail intermediate hosts that inhabit these fresh water bodies -total population of 12 million exposed to the disease Life Cycle of Schistosomiasis Adult worms live in portal and mesenteric veins Mode of infection: SKIN PENETRATION OF CERCARIAE Schistosoma eggs pass out with feces and hatch in fresh Water into miracidia. Intermediate host: Oncomelania snails An area is endemic: 1.Presence of Positive cases 2.Presence of Infected Snails ( Oncomelania quadrasi ) Transmission WASHING OF CLOTHES DEFECATING ON SCHISTO INFESTED AREA. LAUNDERING IN SCHISTO ENDEMIC AREAS S Adult Worm of Schistosoma Japonicum in the Portal Vein LIVE IN THE BLOOD VESSEL CONNECTING THE LIVER WITH THE INTESTINE. AVERAGE LIFE SPAN IS 3-5 YEARS BUT CAN SURVIVE UP TO 30 YEARS OR MORE SCHISTOSOMA EGG PRODUCED/ EGGLAYING 500 – 2000 EGGS / DAY /FEMALE WORM MIRACIDIUM Life span is 48 hrs Infective up to 24 Hrs. CERCARIAE Will survive for a maximum of 3 days, & infective for 36 hrs. Symptomatology : Study showed that : 37.8 % = symptomatic 62.2 % = asymptomatic Symptoms Early Stage: epigastric or abdominal pain bloody-mucoid stool dysenteric attacks fever Advance Stage: enlargement of the abdomen enlargement of the liver and spleen epileptic seizures of the Jacsonian type Cor-pulmonale Soil-transmitted Helminth Infections (ascariasis, trichuriasis, hookworm infection) Caused by: ingestion of eggs from contaminated soil (Ascaris and Trichuris) or skin penetration by larvae from the soil (hookworms) Poor environmental sanitation (open defecation) and poor personal hygiene (dirty hands) are major factors People dirtying the environment for exposure infect other people… Open defecation! -helminth parasites of man include the nematodes (roundworms), trematodes (flukes) and cestodes (tapeworms) -major cause of poor cognitive development and physical retardation and anemia in children -Persevere in areas where poverty or poor economic condition breed poor personal hygiene and inadequate sanitation. - Highly agricultural communities found to be high prevalence of STH. - Erratic migration of ascaris worms can lead to a very serious conditions and even death. s EFFECTS OF STH s Enterobius Vermicularis - Human ‘pinworm” Eggs of E. Vermicularis in Scotch Tape or Cellulose Tape Preparation Life Cycle E. Vermicularis Signs and Symptoms •Frequently asymptomatic •Perianal pruritis •Anorexia •Irritability •Abdominal pain Treatment Mebendazole,Abendazole Strongyloides Stercoralis Signs and Symptoms •Frequently asymptomatic •Abdominal pain •Diarrhea •Pulmonary symptoms Laboratory Diagnosis Identification of larvae (rhabditiform form) through: •DFS –follow-up stool exams 2-4 weeks after treatment to confirm clearance of infection. •FECT Treatment •Ivermectin •Albendazole INTEGRATED CONTROL PROGRAM FOR SCHISTOSOMIASIS AND OTHER INTESTINAL HELMINTHES Case Finding: 1.1 clinical diagnosis * history of exposure * symptoms 1.2 Laboratory diagnosis * stool examination ( K/K method) * blood exam (COPT ) CASE FINDING Use of sanitary toilets and safe water supply reduction in the transmission of schisto by 75 % can be achieved. Use of Sanitary Facilities Use of Foot bridges Control of Stray Animals 25 % reduction of transmission can be achieved environmental sanitation through the use of latrines can prevent contamination of the environment with eggs of STH, schistosomes and food-borne helminthes thus arresting the life cycle. 2. ENVIRONMENTAL SANITATION Health Education Objective: - change undesirable knowledge, attitudes & practices for the improvement of their personal & community health. Health education is needed to convince people to use toilets and to participate in other control and prevention activities of the Government The impact: is measured in terms of health enhancing behaviors; the outcome is reduction in morbidity & mortality Preventive chemotherapy can prevent development of serious morbidity as well as transmission. 85% coverage should be achieved in this intervention. 2. Water , Sanitation And Hygiene ( WASH) Water , Sanitation And Hygiene ( WASH) > serves as the cornerstone in the reduction of diseases specially those related to intestinal parasitism. > is formulated in line with the UNICEF’s water, sanitation, and hygiene strategies for 2006 – 2015. Control of Schistosomiasis x Adult worms live in portal and mesenteric veins CHEMOTHERAPY x Mode of infection: SKIN PENETRATION OF CERCARIAE PERSONAL PROTECTION x Schistosoma eggs pass out with feces and hatch in fresh Water ENVIRONMENTAL SANITATION x Intermediate host: Oncomelania snails SNAIL CONTROL DESIRED BEHAVIOUR CHANGE SUBMIT FOR EXAMINATION & TREATMENT USE OF SANITARY FACILITIES USE OF FOOTBRIDGES, CONTROL OF STRAY ANIMA PARTICIPATE IN SNAIL CONTROL MEASURES Summary: s Schistosomiasis is still a public health problem. Helminthiasis affect people of all ages and cause profound effects esp. on children Kato-Katz is use to diagnose Schistosomiasis and STH An integrated control program can be used for Schisto and STH The DISEASE is influenced by the 3P’s people,parasite,poverty Disposal of excreta containing Schistosome eggs into fresh water SCHISTOSOMIASIS IS SPREAD BY PEOPLE AND NOT BY SNAILS HUMAN PARASITES ARE A REASONABLE INDICATION OF LACK OF PERSONAL CLEANLINESS AND HYGIENE SONIA G. MARGALLO, RMT Schisto/STH/ FWBD Assistant Program Manager