Hormonal Control of
Digestion
Gastrin = hormone produced by
stomach.
• Triggered by entry of
food into the
stomach, and the
stretching of the
Gastrin +
stomach
Gastrin
• Enters the
bloodstream

Gastrin +
• goes back to
the stomach
affecting the
Gastrin
• Promotes the
release of HCl &,
stomach churning
Gastrin +
Cross section of the
stomach
these are the folds
2 kinds of Cells:
2 kinds of Cells:
Cross section of the
stomach
these are the folds
2 kinds of Cells:
2 kinds of Cells:
Cross section of the
stomach
these are the folds
Cross section of the
stomach
these are the folds
Secretin = hormone produced
in cells of the small intestine
• Triggered by HCl
acid in the chyme
• enters bloodstream
and stimulates
pancreatic cells.
• Response = Output
of sodium
bicarbonate buffer.
Secretin = hormone produced
in cells of the small intestine
• ALSO, stimulates
the liver to
produce bile
First hormone discovered
• BILE = emulsifies
FAT
CCK = hormone produced in
cells of the small intestine
• Triggered by
partially digested
protein & fat that
enters the sm.
intestine
CCK
CC
K
CCK = hormone produced in
cells of the small intestine
• Stimulates
Gallbladder
contraction to
release bile
• Stimulates Pancreas
to release enzymes
• Reduces appetite
Enterogastrone
Enterogastrone -
• Hormone produced
in small intestine
• Triggered by acid rich chyme filled
with lipids.
• Target cells in the
stomach and blocks
gastrin
• Slows digestion b/c
digestion of fats
takes more time
Enterogastrone
Enterogastrone -
• Inhibits peristalsis
and acid secretion
of the stomach
• Slows digestion in
the stomach.