Principles of Cardiac Arrest Management Richard Lake 10/2003 Background Information 40% of deaths under the age of 75yrs in Europe are due to cardiovascular disease One third of people who suffer a myocardial infarction die before reaching hospital Most die within an hour of the onset of acute symptoms The majority of these deaths the presenting rhythm is Ventricular Fibrillation or pulseless Ventricular Tachycardia, (VF/ pulseless VT) The only treatment for VF/ pulseless VT is attempted defibrillation With each minute’s delay the chance of a successful outcome fall by 7-10% Once in hospital the incidence of VF after Myocardial Infraction is approximately 5% Most likely presentation of in hospital cardiac arrest is asystole or pulseless electrical activity (PEA). The Chain of Survival Early Access to emergency services or cardiac arrest team Out of hospital summon EMS by dialling 999/112 In hospital call cardiac arrest team ring 2222 (check number when on placement) External chest compressions and ventilation will slow down the rate of deterioration of the brain and heart Basic Life Support should be performed immediately Basic Life Support Danger Response Shout for Help Airway Breathing If no help arrived leave victim, go for help Circulation Danger Check for danger to: Yourself Bystanders Victim Even clinical areas can have dangers, so ALWAYS CHECK Response Check the victim for response Ask a question, ‘hello are you alright?’ Give a command, ‘open your eyes!’ Give a painful stimulus; pinch the shoulder If no response shout for help Checking for response Airway Check the airway Open the airway, place one hand on the victims forehead and gently tilt head back Remove any visible obstruction from the victims mouth, including dislodged dentures. Leave well fitting dentures in place DO NOT ATTEMPT ANY FINGER SWEEPS Opening the airway Jaw thrust technique may be needed if C-spine injury If available use airway adjuncts Nasopharyngeal airway insertion Oropharyngeal airway insertion Breathing Keeping the airway open: Look – for chest movements Listen – at the victims mouth for breath sounds Feel – for air on your cheek Look, listen and feel for no more than 10 seconds to determine if the victim is not breathing. If not breathing and no help has arrived Leave the victim and go to summon help Turn the victim onto his back if he is not already in that position Give 2 effective rescue breaths, each of which should make the chest rise and fall If you have difficulty achieving an effective breath: Recheck the victims mouth and remove any obstruction Recheck there is head tilt and chin lift Make up to 5 attempts to achieve 2 effective breaths Even if unsuccessful move onto check circulation If available use a pocket mask Bag valve mask device may be used Circulation Look, listen and feel for normal breathing, coughing, swallowing, eye flickering, or any movement by the victim If you feel confident check for a carotid pulse You should take no more than 10 seconds to do this Always check pulse same side as you If no breathing but signs of circulation Continue rescue breaths at a rate of 10 breaths per minute After every 10 breaths (every 1 minute) recheck for signs of circulation This should take no longer than 10 seconds to check If no breathing and no signs of circulation Commence CPR at a ratio of 15 Compressions to 2 ventilations Ensure correct hand position The Chain of Survival Out of hospital the aim is to deliver a shock within 5 minutes of the EMS receiving a call In hospital the first healthcare responder should be trained and authorised to use a defibrillator immediately Automated External Defibrillator AED hands off pads Automated External Defibrillators may be used Manual Defibrillator Manual Defibrillator Paddles Defibrillation Defibrillation should be performed promptly Often defibrillation restores a perfusing heart rhythm, this is often inadequate to sustain circulation and further advanced life support is required to improve the chances of long term survival Remember the chain of survival The Universal Treatment Algorithm An important part of Advanced Cardiac Life Support Objectives Recognise the four cardiac arrest rhythms Identify correctly the appropriate algorithm for each of the rhythms Discuss the potential reversible causes of cardiac arrest BLS Algorithm if appropriate Precordial Thump Attach Monitor/Defib Assess rhythm +/- Pulse Check NON VF/VT VF / VT DEFIB X 3 as necessary During CPR Correct reversible causes CPR 1 MIN Check electrode / paddle positions Attempt/verify airway/02/IV access Give adrenaline every 3 mins ? buffers/atropine/ pacing/antiarrhythmics CPR 3 min Re-assess one minute after defibrillation BLS Algorithm if appropriate Precordial Thump if appropriate Attach Monitor/Defib Assess rhythm +/- Pulse Check ? VF / VT Non VF / VT BLS Algorithm if appropriate Precordial Thump Attach Monitor/Defib Assess rhythm +/- Pulse Check VF / VT DEFIB X 3 as necessary CPR 1 MIN During CPR Correct reversible causes Check electrode / paddle positions Attempt/verify airway/02/IV access Give adrenaline every 3 mins ? buffers/atropine/ pacing/antiarrhythmics BLS Algorithm if appropriate Precordial Thump Attach Monitor/Defib Assess rhythm +/- Pulse Check NON VF/VT During CPR Correct reversible causes Check electrode / paddle positions Attempt/verify airway/02/IV access Give adrenaline every 3 mins ? buffers/atropine/ pacing/antiarrhythmics CPR 3 min Re-assess one minute after defibrillation Potentially Reversible Causes Hypoxia Hypovolemia Hyper/ Hypokalemia and metabolic disturbances Hypothermia Tension pneumothorax Tamponade Toxic/ therapeutic disturbances Thrombo-embolic/ mechanical obstruction BLS Algorithm if appropriate Precordial Thump Attach Monitor/Defib Assess rhythm +/- Pulse Check NON VF/VT VF / VT DEFIB X 3 as necessary During CPR Correct reversible causes CPR 1 MIN Check electrode / paddle positions Attempt/verify airway/02/IV access Give adrenaline every 3 mins ? buffers/atropine/ pacing/antiarrhythmics CPR 3 min Re-assess one minute after defibrillation Drugs used commonly during resuscitation Epinephrine (Adrenaline) Atropine Amiodarone Magnesium Sulphate Lidocaine (Lignocaine) Sodium Bicarbonate Calcium Epinephrine (Adrenaline) First line cardiac arrest drug, given after every 3 minutes of CPR Dose 1mg (10ml of 1 in 10,000) IV Causes vasoconstriction, increased systemic vascular resistance increasing cerebral and coronary perfusion Increases myocardial excitability, when the myocardium is hypoxic or ischaemic Atropine Given for asystole or pulseless electrical activity with a rate less than 60 beats per minute 3mg is given as a single intravenous dose It blocks the activity of the vagus nerve on the SA and AV nodes, increasing sinus automaticity and facilitating AV node conduction Amiodarone For Refractory VF/VT; haemodynamically stable VT and other resistant tachyarrhythmias If VF or pulseless VT persists after the first 3 shocks then Amiodarone 300mg is considered. If not pre-diluted, must be diluted in 5% dextrose to 20ml. (Will crystallise is mixed with saline) Should be given centrally but in an emergency can be given peripherally Increases the duration of the action potential in the atrial and ventricular myocardium Magnesium Sulphate For refractory VF when hypomagnesaemia is possible; ventricular tachyarrhythmias when hypomagnesaemia is possible In refractory VF – 1 to 2g (2-4ml of 50% magnesium sulphate) peripherally over 1 to 2 minutes. Other circumstances 2.5g (5ml of 50% magnesium sulphate) over 30 minutes Lidocaine (Lignocaine) For Refractory VF/ pulseless VT (when Amiodarone is unavailable 100mg for VF/ pulseless VT that persists after three shocks. Another 50mg can be given if necessary Sodium Bicarbonate Given for severe metabolic acidosis and Hyperkalaemia 50mmol (50ml of 8.4% solution), where there is an acidosis or cardiac arrest associated with Hyperkalaemia Calcium Administered when pulseless electrical activity caused by: Hyperkalaemia Hypocalcaemia Overdose of Calcium channel blocking drugs Dose 10ml of 10% calcium chloride repeated according to blood results Summary Cardiac arrest can have a variety of causes The chain of survival is essential to improve outcome from cardiac arrest Awareness of the universal treatment algorithm is important A knowledge of the drugs used in cardiac arrest, their routes and dilution is also essential Questions References Resuscitation Council (UK). (2000) Advanced Life Support Provider Course Manual . 4th Edition. Resuscitation Council (UK).:London Resuscitation Council (UK). (2002) Immediate Life Support Course Manual . 1st Edition. Resuscitation Council (UK).:London