Hunter S. Lewis, DVM, DABVP
Greene, Lewis and Associates
www.greenelewis.com
Osteoarthritis
1. Degenerative Joint Disease (DJD)
2. Characterized by cartilage damage,
new bone formation
effusion.
3. Caused by “use trauma”
and
joint
Osteocondritis Dessicans (OCD)
Subcondral Bone Cysts
Osteoarthritis

Fetlock
Osteoarthritis

Fetlock
Osteoarthritis

Hock
Osteoarthritis
Osteocondritis Dessicans (OCD)
1.
Developmental Orthopedic Disease (DOD)
2.
Characterized by failure of normal bone
formation
Subcondral Bone Cysts
Osteoarthritis
Osteocondritis Dessicans (OCD)
3.
Causes:
a.
b.
c.
d.
e.
4.
Genetic predisposition
Rapid growth
Nutrition
Mineral Imbalances
Endocrine Factors
Can result in DJD
Subcondral Bone Cysts
Osteocondritis Dessicans (OCD)

Stifle
Osteocondritis Dessicans (OCD)

Hock
Osteoarthritis
Osteocondritis Dessicans (OCD)
Subcondral Bone Cysts
Development Orthopedic Disease
Characterized by failure of normal bone
formation and loss of normal bone
3. Same causes as OCD but trauma is also
involved.
4. Can result in DJD
1.
2.
Subcondral Bone Cysts

Stifle
Subcondral Bone Cysts

Stifle
Subcondral Bone Cysts

Fetlock
Assessment of Joint Treatment
 Symptom-Modifying Osteoarthritis Drug
(SMOAD)
 Disease-Modifying Osteoarthritis Drug
(DMOAD)
Types of Joint Treatment
 Oral
 Injectable
 Intra-articular
Types of Joint Treatment
 Oral
1. Glucosamin
2. Chondrotin Sulfate
3. Anti-inflammatories
4. ASU – Avocado, Soybean
Unsaponifiable Extracts
Types of Joint Treatment
 Oral
4. ASU – Avocado, Soybean
Unsaponifiable Extracts
a.
b.
c.
d.
Did not improve lameness
Reduced damage to joint
Increased production of glycosaminoglycan
Stimulated cell and tissue repair
Types of Joint Treatment
 Injectable
1. Adequon
2. Legend
3. Generics
a. Polyglycan
b. Map 5
4. Tildren
Types of Joint Treatment
 Injectable
4. Tildren




Inhibits bone resorption and may
promote bone reformation
Shown effective in hock osteoarthritis
and navicular syndrome
Most effective if used early in disease
Cost ??
Types of Joint Treatment
 Intra-articular
1. Corticosteroids
2. Hyaluronic Acid
3. IRAP – Interleukin-1 Receptor
Antogonist Protein
Types of Joint Treatment
 Intra-articular
3. IRAP – Interleukin-1 Receptor
Antogonist Protein

or ACS – Autologous Condition Serum
 Blocks IL-1 release
 Reduces negative effects of
inflammation
 Reduces pain
 Improves synovial membrane health
Types of Joint Treatment
 Other
1. Extrocorporeal Shockwave
Therapy
2. Surgery
3. Alternative Therapies