Pituitary Gland
Posterior Lobe
BY: ELENA SEIFERT & KRISTEN THORNE
PERIOD 8
1/8/14
Location
 Part of the brain
What type of hormones are produced?
 ADH (antidiuretic hormone)
 Oxytocin
How do these hormones affect the body?
 ADH- Promotes reabsorption of water by the kidneys
 Oxytocin- strongly affects human social interactions,
stimulates uterine contractions during childbirth and
facilitates breast feeding

AKA the “love hormone”
Maintenance of homeostasis
 ADH- helps maintain water and electrolyte balance
 The pituitary and the hypothalamus glands work
together to regulate the release of other hormones in
the body.
Feedback Mechanisms
 ADH- when there is not enough water in the blood ADH is
secreted so the kidneys reabsorb water (negative feedback)
 Oxytocin- during childbirth, oxytocin is released to
stimulate uterine contraction and lactation from the
mammary glands (positive feedback)
Antagonistic Hormones
 Vasopressin Receptor Antagonist (VRA)- blocks
ADH for those with congestive heart failure
 Atosiban (oxytocin receptor antagonist)- blocks
Oxytocin to control emotions and hormones
Disorders
 With a damaged or malfunctioning pituitary gland,
your body would lose the normal ability to regulate
the hormones released by most endocrine glands.
 Disorders of the posterior pituitary gland are:


diabetes insipidus
Syndrome of Inappropriate Antidiuretic Hormone Secretion
(SIADH)
Diabetes insipidus
 Condition where the kidneys are unable to conserve
water due to lack of ADH
 Symptoms

Extreme thirst
Excessive urine volume
 Treatment Medication (vasopressin)
SIADH
 Condition where high levels of ADH cause the
kidneys to absorb excessive amounts of water.
 Symptoms



Nausea/vomiting
Cramping
Seizures
Coma
 Treatment Surgery to remove the gland releasing ADH
 Medication to block ADH
Sources
 http://someinterestingfacts.net/wp-content/uploads/2012/12/Pituitary-gland.jpg
 http://droualb.faculty.mjc.edu/Course%20Materials/Physiology%20101/Chapter%
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20Notes/Fall%202011/chapter_6%20Fall%202011.htm
http://scientopia.org/blogs/scicurious/2009/11/09/oxytocin-starting-with-thebasics/
http://www.emoryhealthcare.org/pituitary/pituitary-gland.html
http://faculty.clintoncc.suny.edu/faculty/michael.gregory/files/bio%20102/bio%20
102%20lectures/endocrine%20system/endocrin.htm
http://www.frontalpioneer.com/2013/04/adhoxytocinprolactin-podcast.html
http://www.drugs.com/drug-class/vasopressin-antagonists.html
http://www.lpch.org/DiseaseHealthInfo/HealthLibrary/diabetes/siadh.html
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001415/#adam_000377.diseas
e.symptoms
http://www.urmc.rochester.edu/Encyclopedia/Content.aspx?ContentTypeID=90&
ContentID=P01974