Mitosis Flipbook By Trevor Interphase: This is where cell performs normal functions and grows. As it grows in size, it will transition into late interphase. In late interphase, DNA will replicate. While this occurs, the DNA molecule unwinds using the help of an enzyme, new bases pair with ones on the original DNA, and two new identical DNA molecules are created. Early Prophase In this phase, the replicated chromosomes will coil into an X shape. As this occurs, the nucleolus will disappear and the spindle fibres start to be formed. Late prophase In this phase, after the spindle fibres are formed, the spindle fibres will attach to centromeres of chromosomes. Metaphase In this phase, the X shaped chromosomes will align at the equator of the cell. Anaphase In this phase, the X shaped chromosomes will be pulled apart by the spindle fibres. When this happens, the X shaped chromosomes split in two, becoming sister chromatids. Each sister chromatid head to opposite poles of the cell. Telophase In this phase, the cells begin to separate. When this happens, spindle fibres will disappear and a nuclear membrane will form around each of the separated set of chromosomes. This is also where the nucleolus reappears inside each of the nuclear membranes. Cytokinesis This is where the cell membrane pinches together and divides the cell’s cytoplasm and organelles. Once this happens, they then form into two daughter cells. The whole process then repeats.