MRI Physics 3: Hardware Douglas C. Noll Biomedical Engineering University of Michigan MRI Hardware • Recall the three magnetic fields – B0 – B1 – Gx, Gy, Gz • Also, we need pulse control and data acquisition systems Noll Major MRI Components RF Screen Room Main magnet Gradient Coil RF Coil Receiver Sampler RF Amp Real-Time Controller Gradient Amps Display & Console Operator’s Computer Disks Noll RF Screen Room • Encloses the MRI device • Shields MRI scanner from electromagnetic noise from computers, radio stations, etc. – MRI signals are weak compared to noise sources – Any wires going in/out must be filtered and grounded so they don’t introduce noise • These rooms can also incorporate magnetic shielding to contain the magnetic field. Noll The Main Field • B0 range: 0.2 T to 7 T • Higher fields: – – – – – Higher SNR Slightly longer T1’s, Poorer RF homogeneity Higher power deposition Higher cost • Typically superconducting Noll The Main Field • Safety issues: – – – – – – Noll Attraction of ferrous objects Attraction of metallic implants (e.g. cochlear implants, neurostimulators, pacemakers, and poorly designed/manufactured stents, screws, pins, aneurysm clips, etc.) Attraction of foreign metal objects (metal in eyes, shapnel, ingested ferrous objects). Affects magnetic switches in pacemakers Some reports of dizziness, light flashes, unusual tastes, etc. at very high magnetic fields. The FDA has classified 7 T and under as a “nonsignificant risk.” RF Fields • RF coils must generate a rotating (or oscillating) magnetic field – Ideally uniform application of B1 • RF coils also detect precessing magnetization – Ideally sensitive mainly to tissue of interest – Uniformity is of secondary importance • Three main types: – Volume Coils – Surface Coils – Arrays Coils (which are basically arrays of surface coils) Noll RF Coils Volume Coils Birdcage Coil Saddle Coils Array Coil Noll Surface Coil RF Coils • Typical Coils – Head Coil (volume birdcage coil) – Body Coil (volume, mostly transmit only) – Surface Coils (e.g. occipital coils for visual system studies, mostly receive only) • Improved SNR vs. volume coils – Head Array (array of surface coils, receive only) • The idea here is that one can receive the benefits of surface coils, but over a larger volume. • Also allows use of parallel MRI technology. Noll RF Fields • Safety issues: – RF heating of the body (FDA limits our power deposition) – Focal RF heating around metals (glasses, jewelry, implants, some tattoos, etc.) can lead to burns – Focal heating near implanted devices e.g. cochlear implants, neurostimulators, pacemakers, and poorly designed/manufactured stents, screws, pins, aneurysm clips, etc.) Noll Gradient Fields • High power amplifiers generate magnetic fields in the same direction as B0, but with variations along x, y and z. Noll z x Gradients x-gradient (G ) y x z x y y-gradient (Gy) z x y z-gradient (Gz) Noll Gradient Coil Designs z B(z) B(x) x Z Gradient Noll X,Y Gradient Gradient Fields • Safety issues: – – Noll Rapid changes of fields can lead to peripheral nerve stimulation (e.g. like a twitching in the back). FDA guidelines state that stimulation cannot be “painful.” The gradients are also responsible for the substantial acoustic noise. FDA says it can’t exceed 99 dBA with hearing protection in place. Additional Slides Noll Typical fMRI Protocol • Scout Acquisition – Where am I? • T1-weighted images – To align structure to fMRI maps • T2-weighted images – To rule out pathology • fMRI – T2*-weighted, dynamic – EPI or spiral • High-resolution 3D T1-weighted images – For segmentation of anatomy Noll