Investor Presentation 1 May 2014 TSX:MBX Forward-Looking Statements Certain of the statements contained in this presentation are forward-looking statements within the meaning of applicable securities laws, including, but not necessarily limited to, the “safe harbour ” provisions of the Securities Act (Ontario). These statements involve known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of the Company, or industry results, to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. Microbix does not assume responsibility for the accuracy and completeness of these forward-looking statements. The Company does not undertake any obligation to publicly update or revise these forward-looking statements to reflect subsequent events or circumstances. This cautionary language applies expressly to the forward-looking statements included herein. 2 TSX:MBX Investment Highlights • Commercial virology business produces and supplies the world’s largest range of native infectious disease antigens • 2013 financial turnaround • Advancing major pipeline opportunity: LumiSort™ (livestock semen sexing) • VIRUSMAX™ (influenza vaccine yield enhancement) represents a potential “free call option” • Upcoming milestones should provide near- and mid-term value inflections 3 TSX:MBX Commercial Virology Business Provides Solid Foundation For Growth • Founded in 1988 • Produces and supplies infectious disease antigens, primarily for the diagnostics market • Products enjoy “gold standard” positioning • Customers include many of the top global diagnostics products companies 4 TSX:MBX 2013 ”Performance Improvement Program” Key Profitability Turnaround $7.6 $8.0 $6.1 $6.0 $6.7 $6.0 Q1 – 2014 $5.0 $4.4 $4.0 $6.5 $3.6 Revenue doubled: $1.9M $4.0 Operating income: $214,000 EBITDA: $495,000 $2.0 $0.2 $0.1 $0.0 -$2.0 -$2.1 -$4.0 -$2.7 -$3.7 2005 2006 2007 2008 2009 2010 2011 2012 2013 Revenue 5 -$2.3 -$2.5 -$2.6 -$2.6 Loss Profit TSX:MBX Growth Strategy For 2014 • Growth Strategy: –Continue to increase share and profitability of virology business –Leverage resources to help drive pipeline • VIRUSMAX™: –Unlock value by enforcing our patents • Lumisort™: –Complete prototype to prove patent claims 6 TSX:MBX Influenza Vaccine Yield Enhancement Technology TSX:MBX Global Trends Driving Need For Improvements to Influenza Vaccine Manufacturing • Limited to a small number of competitors (Merk, GSK, Sanofi Pasteur, Wyeth, Novartis) – Insufficient capacity for emerging markets, especially in the event of a pandemic – Governments reluctant to allow import-dependent mass vaccination campaigns • Need for high volume/high quality domestically manufactured product located in key emerging countries/regions 8 TSX:MBX Our Solution: VIRUSMAX™ • Proven to double output of traditional manufacturing process • VIRUSMAX™ patents issued in 21 major markets including US, Canada, Europe, India, China and Australia 9 TSX:MBX Unlocking Value From VIRUSMAX™ • Original plan was to bring technology to global market via JVs • 2013 strategic review resulted in focus shifting to protection and monetization of the VIRUSMAX™ IP – January 6, 2014: commenced a U.S. patent infringement litigation against Novartis in Texas – January 23, 2014: successfully defended all of its VIRUSMAX™ patent claims against a challenge by Novartis at the European Patent Office • Legal activities to advance throughout 2014 • Represents a “free call option” on MBX 10 TSX:MBX Livestock Semen Sexing Technology 11 Dairy Products Are a Major Source of Dietary Protein Food Group Meat & Alternatives Milk & Alternatives Grain Products Vegetables Food Protein* Beef sirloin steak, 75 g 26 g Chicken, skinless breast, 75 g 20 g Cottage cheese, 125 mL (½ cup) 15 g Milk, 250 mL (1 cup) 8g Whole-wheat bread, 1 slice 3g Brown rice, cooked, 125 mL (½ cup) 3g Broccoli, cooked, 125 mL (½ cup) 2g Butternut squash, cooked, 125 mL (½ cup) 1g *Health Canada; Canadian Nutrient File (CNF), 2007 12 TSX:MBX By 2050, the World’s Population Will Require 100% More Protein • As per capita income >$5,000/year, diets shift from grains to animal protein • Increased land use can only address 20% of need for more protein • LumiSort™ will contribute to closing the protein gap by optimizing dairy and beef production efficiency – Constant drive for genetic improvement to livestock – Efficiency of converting animal feed to human food 13 TSX:MBX Sex Preselection Advantage to Farmers • Dairy farmers want female calves – Replace 35% of their herd every year – Females are the only ones that produce milk – Cows need to be constantly bred to keep producing milk – Recent studies: cows pregnant with female fetuses produce 2.5% more milk 14 TSX:MBX Global Livestock Semen Market Is Well-Established • Almost all dairy cows are artificially inseminated with a “straw” purchased from a semen distributor Region Sales, USD North America $200M South America $125M Europe $550M China $40M India $40M Russia $60M Oceania $20M Other $175M Total >$1.2B* * Despite strong drivers, technology limitations have resulted in sexed semen capturing <5% of market TSX:MBX 16 LumiSort™ Overcomes the Low Yield and Fertility Rate Issues That Hamper Competitive Technology Lumisort™ Competitor • • + – – – M ? F • Fluid sprayed into droplets • Undesired cells rendered infertile • Continuous liquid stream: – Droplet size = speed limit (~8,000 cells/sec. maximum) + + Sex identification <50% efficient • Sperm cells damaged by: Sex identification >90% efficient – >100,000 cells/sec – Spray (depressurization) – No explosive decompression – Charge – No electric shock – Sudden stop – No collision with collection vessel Overall yield <30% “Killing” Laser Collector Overall yield >90% TSX:MBX Value Proposition of LumiSort™ Segment PRODUCERS (Farmers) Technology Competitor LumiSort™ 90 Straws 270 Straws (@ $20 each = $1,800) (@ $20 each = $5,400) 9-10 Straws/Hour 90 Straws/Hour Accurate Sex Selection High Fertility rates SEMEN DISTRIBUTORS Yield Per Ejaculate Productivity 17 TSX:MBX Already Negotiated Term Sheet Agreements with 25% of Global Livestock Genetics Companies Small sales force requirement No entry/capital cost for customers Sexed semen is market expanding Attractive recurring revenue model for MBX ~40 semen distributors service global market We provide equipment Producers operate We maintain Significant distributor mark-up $1 per sexed semen straw + 15% of the gross sales TSX:MBX Significant Revenue Potential Even at Low Penetration Rates Estimated Straws Purchased Worldwide ~ 200 Million Average Lumisort™ Revenue Per Straw Sold $4.15 LumiSort™Annual Revenues ($ in millions) Annual Revenue Level $50 $100 $200 $400 Market Share Required 6.0% 12.1% 24.1% 48.2% TSX:MBX Strong Patents Will Help Drive Widespread Market Adoption • LumiSort® U.S. patent 8,004,661 granted August 24, 2011 – Sexing Technologies has twice challenged the patents – USPTO has rejected these challenges both times • Patent filed internationally in large dairy and beef producing countries – Canada, Europe, Mexico, China, Brazil, Chile and others 20 TSX:MBX 2014 Strategic Plan for LumiSort™ • Prove our patent claims work in practice • Prototype will process sperm cells by year’s end – Dedicated funding in place • Lathrop Engineering engaged to build and test prototype • Target completion end of 2014 – Industry showcase event upon completion 21 TSX:MBX Summary In Summary • Growing and profitable commercial virology business • Well defined, significant new LumiSort™ market opportunity • VIRUSMAX™ potential “free call option” • Strong management team with a record of industry success • Near- and mid-term value inflections 22 TSX:MBX