1. Tuberculosis case reports, UK, 2000-2012 1 Tuberculosis in the UK: 2013 report Figure 1.1: Tuberculosis case reports and rates, UK, 2000-2012 10,000 15 14 9,000 13 8,000 12 Number of cases 10 6,000 9 8 5,000 7 4,000 6 5 3,000 Rate (per 100, 000) 11 7,000 4 2,000 3 2 1,000 1 0 0 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 Year Number of cases Rate per 100,000 Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI), Office for National Statistics (ONS) Data as at July 2013 Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England 2 Tuberculosis in the UK: 2013 report Figure 1.2: Tuberculosis case reports and rates by country, UK, 2012 10,000 18.0 Number of cases 9,000 Rate per 100,000 16.0 8,000 14.0 Number of cases 12.0 6,000 10.0 5,000 8.0 4,000 6.0 Rate (per 100, 000) 7,000 3,000 4.0 2,000 2.0 1,000 0 0.0 England Northern Ireland Wales Scotland Total Country Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI), Office for National Statistics (ONS) Data as at July 2013 Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England 3 Tuberculosis in the UK: 2013 report Figure 1.3. Three-year average tuberculosis case rates by local area*, UK, 2010-2012 *England – Local authorities, Wales and Scotland – Health Boards, NI – data not available London © Crown copyright and database rights 2013 Ordnance Survey 100016969 Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI), Office for National Statistics (ONS) Data as at July 2013 Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England 4 Tuberculosis in the UK: 2013 report Figure 1.4: Tuberculosis case reports and rates by region*, England, 2012 4,000 3,500 50 41.9 Number of cases 45 Rate (per100,000) and 95% CI 40 3,000 Number of cases 2,500 30 2,000 25 19.4 20 1,500 1,000 11.3 11.5 9.3 15 10.8 7.8 5.8 500 0 Region * HPA region CI – 95% confidence intervals Source: Enhanced Tuberculosis Surveillance (ETS), Office for National Statistics (ONS) Data as at July 2013 Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England Tuberculosis in the UK: 2013 report 10 5 0 5 6.4 Rate (per 100, 000) 35 Figure 1.8: Non UK-born tuberculosis case reports by time since entry to the UK to tuberculosis diagnosis, UK, 2012 600 Number of cases 500 400 300 200 100 0 0 5 10 15 20 25 30 35 Years since entry to diagnosis Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI) Data as at July 2013 Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England 6 Tuberculosis in the UK: 2013 report 40 45 50+ Table 1.1: Most frequent countries of birth for non UK-born tuberculosis cases, UK, 2012 Country of birth Number of Percentage cases of cases* Median time since entry UK (IQR)** India 1,858 30.7 4 (2 - 13) Pakistan 1,091 18.0 7 (2 - 21) Somalia 380 6.3 8 (3 - 12) Bangladesh 276 4.6 7 (2 - 23) Nepal 216 3.6 2 (1 - 5) Nigeria 184 3.0 5 (1 - 10) Philippines 136 2.3 5 (2 - 9) Zimbabwe 132 2.2 9 (7 - 11) Kenya 98 1.6 13 (6 - 40) Sri Lanka 98 1.6 7 (2 - 15) Eritrea 87 1.4 4 (2 - 5) Romania 78 1.3 2 (0 - 4) Afghanistan 75 1.2 5 (2 - 10) Poland 71 1.2 5 (2 - 7) Others (each <1%) 1,265 21.1 5 (1 - 13) Total* 6,045 100 6 (2 -13) * Where country of birth was known; **Years Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI) Data as at July 2013 Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England 7 Tuberculosis in the UK: 2013 report Figure 1.10: Tuberculosis case reports and rates by age group and place of birth, UK, 2012 1,200 140 1,100 Number of cases 900 100 800 700 80 600 60 500 Rate (per 100,000) 120 1,000 400 40 300 200 20 100 0 0 Age group (years) UK-born Non UK-born Rate in UK-born Rate in non UK-born Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI), Office for National Statistics (ONS) Data as at July 2013 Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England 8 Tuberculosis in the UK: 2013 report Figure 1.12: Tuberculosis case reports and rates by place of birth, UK, 2000-2012 7,000 120 98 88 Number of cases 5,000 100 91 93 86 85 89 86 82 76 84 80 77 80 4,000 60 3,000 40 Rate (per 100,000) 6,000 2,000 1,000 20 4 4 4 4 4 4 4 4 4 4 4 4 4 0 0 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 Year UK-born Non UK-born Rate UK-born Rate Non UK-born Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI), Office for National Statistics (ONS) Data as at July 2013 Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England 9 Tuberculosis in the UK: 2013 report Figure 1.13: Proportion of tuberculosis case reports by site of disease (pulmonary/extra-pulmonary), UK, 2000-2012 100 90 80 Percentage of cases (%) 70 60 50 40 30 20 10 0 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 Year Pulmonary Extra-pulmonary Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI) Data as at July 2013 Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England 10 Tuberculosis in the UK: 2013 report 2010 2011 2012 Table 1.2: Tuberculosis case reports by site of disease, UK, 2012 Site of disease* Number of cases 4,563 Percentage** 52.1 Extra-thoracic lymph nodes 1,872 21.4 Intra-thoracic lymph nodes 946 10.8 Other extra-pulmonary 619 7.1 Pleural 651 7.4 Gastrointestinal 471 5.4 Bone – spine Cryptic ± 394 4.5 46 0.5 ± 197 2.3 Bone – other 218 2.5 CNS – meningitis 187 2.1 Genitourinary 137 1.6 CNS – other 80 0.9 Laryngeal 16 0.2 Unknown extra-pulmonary 15 0.2 Pulmonary Miliary *With or without disease at another site ±For **Percentage of cases with known sites of disease (8751) Scotland cases, this includes both cryptic and miliary site CNS - Central Nervous System Total percentage exceeds 100% due to infections at more than one site Source: Enhanced Tuberculosis Surveillance (ETS), Enhanced Surveillance of Mycobacterial Infections (ESMI) Data as at July 2013 Prepared by: TB Section, Centre for Infectious Disease Surveillance and Control, Public Health England 11 Tuberculosis in the UK: 2013 report