The central nervous system the spinal cord Xiaoming Zhang Department of Human Anatomy School of Medicine Zhejiang University The Spinal Cord 1. External features: Location: foramen magnum -- lower border of first lumbar vertebra Shape: A long cylindrical structure Enlargements: cervical enlargement lumbar enlargement Conus medullaris Filum terminale • main longitudinal fissure and sulci on surface: Cauda equina posterior lateral posterior median sulcus sulcus Filum terminale anterior lateral sulcus anterior median fissure • Spinal segment: It's a part of spinal cord, which is connected with the rootlets of a pair of spinal nerve. 31 segments 8 cervical segments 12 thoracic segments 5 lumbar segments 5 sacral segments 1 coccygeal segments Corresponding relationship between spinal segments and vertebrae spinal segments C1-C4 C5 ~ T8, T l~ T4 correspond to vertebrae C1-C4 C4 - C7, C7 ~ T3 T5 ~ T8 T3 ~ T6 T9-T12 T6-T9 L1-L5 T10-T12 S l~S5,Co1 LI 2. Internal structure The central canal central canal Gray matter: parts: Lateral horn (only extends from Tl posterior horn Intermediate zone Lateral horn to L3 segments.) gray commissure (anterior and posterior ) anterior horn Gray matter gray commissure Main nuclei: anterior horn: medial group lateral group intermediate zone: intermediolateral nucleus intermediomedial nucleus the nucleus posteromarginalis the substantia gelatinosa the nucleus proprius the dorsal nucleus (thoracic nucleus) posterior horn: the nucleus posteromarginalis the substantial gelatinosa the nucleus proprius: the dorsal nucleus (thoracic nucleus) intermediolateral nucleus Intermediomedial nucleus: lateral group medial group The nuclei and the laminas the nucleus posteromarginalis the substantia gelatinosa the nucleus proprius the dorsal nucleus (thoracic nucleus) intermediolateral nucleus Intermediomedial nucleus: lateral group medial group White matter: parts: posterior median sulcus posterior funiculus posterior lateral sulcus lateral funiculus anterior lateral sulcus anterior white commissure anterior median fissure anterior funiculus Main tracts (or fasciculi): long ascending tracts: fasciculus gracilis: come from sacral, lumbar and lower six thoracic nerves, terminate upon nucleus gracilis fascicules cuneatus: come from cervical and upper six thoracic nerves, terminate upon nucleus cuneatus. *conduct the fine tactile (e.g.two-point discrimination) and kinesthetic sense (e.g.position and movement and vibration)of the ipsilateral trunk and limbs. fascicules cuneatus fascicules gracilis lateral and anterior spinothalamic tracts: *in corresponding funiculus *arises from opposite nucleus proprius *terminate on thalamus *conduct pain, thermal and rough tactile sense of opposite trunk and limbs thalamus anterior spinothalamic tracts anterior spinothalami c tracts nucleus proprius main long descending tracts lateral corticospinal tract: *arises from opposite cerebral cortex *descends through lateral funiculus of spinal cord *terminate on ipsilateral anterior horn (lateral group) *controls the contraction of skeletal muscles of ipsilateral limbs anterior corticospinal tract: *controls the movement of bilateral muscles of trunk lateral corticospinal tract anterior corticospinal tract Other descending tracts: they are related to regulate muscle tonus Fascicules gracilis fascicules cuneatus lateral corticospinal tract Rubrospinal tract anterior spinothalami c tracts Reticulospinal tract anterior spinothalamic tracts vestibulospinal tract tectospinal tract anterior corticospinal tract Functions: • To convey afferent impulses, which come from somatic and visceral receptors to the brain, and conduct efferent impulses from brain to effectors. • Related to reflexes