Ostium Secundum Atrial Septal Defect Closure Thomas Hoy Department of Biomedical Engineering BME 272 Senior Design Background What is a Ostium Secundum Atrial Septal Defect? • • congenital heart disease causes left to right shunting across interatrial septum Why should we care? • Isolated secundum atrial septal defects of significance occur in approximately 70,000100,000 individuals today. • Isolated ASDs can cause congestive heart failure or Eisenmengers syndrome Techniques Used Today Surgical Suture & Surgical Patch • Both require open heart surgery • Requires stopping the patient's heart and utilizing cardiopulmonary bypass Transcatheter Amplatzer septal occluder • Pioneer in 1976 • Minimally invasive with excellent results Both Cost The Same Project Definition To design a device that should: • Provide more accurate application • Less strain on the applied interatrial wall • Stimulate endotheliazation of the device • Be lower in cost and more simplistic in design • Improve the quality of life of the patient Current Status Research • History of device and methods used • Success rate and cost analysis of those devices an methods • Study of the engineering aspects of the Amplatzer design Brainstorming possible solutions to this problem Future Work Scheduled meeting with advisor to discuss progress Continued brainstorming and documentation of possible designs and implementation devices Study engineering possibilities of designs and modeling Model