Management of Severe Head Trauma in A&E Dr. David Tran A&E department FVHospital 17 mars 2010 Management of head injury Primary survey: ensure that airways, breathing, circulation and cervical spine are secure. Assessment of mental state (glasgow score adapted to the age) Alert (A), responds to voive (V), Responds to pain (P), unresponsive (U) Perform secondary survey Neck & cervical spine (tenderness, muscle spasm) Head: scalp hematoma, laceration, swelling, tenderness… Eyes: pupils size, equality, reactivity Ears: otorrhage, hemotympan Nose, mouth, facial fractures Motor function: limbs, reflexes, lateralised weakness, Babinski’s sign. Seriousness of head trauma Glasgow Score < or = 8 (severe head trauma) Glasgow score 9-12 (moderate head trauma) Glasgow score > or = 13 (mild head trauma) Adapted Glasgow Coma Scale Do not forget neck protection Severe head trauma are frequently associated with neck injuries. Those injuries often concern the cervicooccipital region (C1/C2) Neck collar has to be put immediately at arrival in A&E and will be removed only after imaging. General management IV line, use infusion of isotonic solutions* (NaCl 0.9% is the most adapted) Intubation: all patients with severe head trauma (Glasgow score < or =8) have to be intubated. Crash induction is the gold standard for management of airways. * Avoid hypotonic solutions like G5% or Ringer Lactate Induction / sedation Crash induction: Etomidate 0.3mg/Kg & Suxamethonium 1mg/Kg Orotracheal intubation Immediate sedation with Hypnovel / (becareful of the neck) Fentanyl IV is very important to control intracranial pressure (continuous infusion following protocole sedation in SMUR: 10 amp. Hypnovel /1 amp. Fentanyl) Interest of early sedation in case of severe head trauma Control agitation of the patient Control of analgesia Avoid or decrease intra-cranial hypertension. Adaptation to mechanical ventilation Monitoring head trauma in A&E Non invasive blood pressure/15 min SpO2 Pulse rate on scope PCO2 (if not available, blood gaz during mechanical ventilation) Intracranial pressure monitoring (PPC= MAP-ICP) Each time there is a severe traumatic brain injury (with GCS 3-8) associated with CT scanner images of hematomas, contusions, swelling, herniation or compressed basal cisterns. Head CT scanner abnormalities Left Epidural hematoma Effacement of left ventricle Shift >10mm of the medium line Signs of ICH Head CT scanner abnormalities (2) Right Sub-dural hematoma Shift > 10mm of the medium line Effacement of the right ventricle Head CT scanner abnormalities (3) Frontal contusions (hemorrhages) Effacement of the cisterns and subarachnoid spaces Head CT scanner abnormalities (4) Hyperdense lesion in R. frontal lobe = cerebral contusion Biconvexity in the left petrus temporal = HED CT scanner abnormalities (5) Ventricles & subarachnoid spaces obliterated = ICH Sub-arachnoid hemorrhage CT Scanner abnormalities (6) Sub-arachnoid hemorrhage in posterior fossa Recommandations Blood pressure should be monitored and hypotension avoided (Pas > 90mmHg) Oxygenation should be monitored and hypoxemia avoided (Pa O2 > 60mmHg SpO2>90%) Mannitol is effective for control of raised intra-cranial pressure (ICP) Signs of intra-cranial hypertension (ICH) Signs of transtentorial herniation / ICH: anisocoria, mydriasis, neurological lateral signs, seizures, bradycardia, hypertension, bradypnea. Progressive neurological deterioration not attributable to extra-cranial causes. Those signs are an indication for immediate use of bolus of Mannitol (up to 1mg/Kg/20 min.) Use of Mannitol Indication: Signs of intra cranial hypertension Mannitol 20 or 25% (20g/100ml or 25g/100ml) Bolus 0.25 to 1g/Kg/20 min. Exp: body weight 60 kgs > 15g to 60g IV in 20 min. = 100 to 300ml Mannitol 20% Administration of Mannitol Mannitol is superior to Barbiturates for control of high ICP after TBI. The osmotic effect of Mannitol is delayed for 15-30 min. while gradients are established between plasma & cells. Its effects persist for about 90 min. to several hours. Use of hypertonic Saline (HS) Osmotic mobilization of water across blood brain-barrier. (Saline 7,2% or 10%) HS as a bolus infusion could be an effective adjuvant to Mannitol to treat ICH. Potential side effects: central pontic myelinolysis in patient with chronic hyponatremia. More studies are required to determine the place of HS in the treatment of ICH. Goals for management of severe head trauma Any episode of hypotension or hypoxia increases head injury mortality. Systolic blood pressure > 90mmHg (ideal = SBP 120mmHg & MAP 85mmHg ) SpO2 > 90% (PaO2> 60mmHg) Management of severe head trauma in A&E Neck collar Monitoring BP, pulse, SaO2 IV line and fluid infusion (NaCl 0.9%) to restore systolic BP >90mmHg Intubation (crash induction) and mechanical ventilation. Immediate sedation after intubation (hypnovel/fentanyl) Interest of early CT scanner CT scanner has to be performed before transfert to neurosurgical center. The time you spend to perform CT in FVH (<15min.) is time you save for the patient later. (timing in CR is probably longer) Management of imaging Head CT scanner without injection Complete by images of cervico-occipital and cervical region. Chest Xray and Pelvis Xray are systematic Thorax, abdomen and dorso-lombar rachis CT scanner are requested according clinical signs. Indication of early neurosurgery Neurosurgery in emergency