Department of Critical Care Medicine Kovai Medical Center and Hospital Supportive Care of Patients on Mechanical Ventilation Dr.M.N.Sivakumar DA.,DNB.,IDCCM.,EDIC., Senior Consultant in Critical care Head - Dept. of Critical Care Medicine Kovai medical Center and Hospital ACKNOWLEDGEMENT Dr Ram E Rajagopalan, AB (Int Med), AB (Crit Care) Dr Mahendran, MD Dr N Selvarajan, MD Department of Critical Care Medicine Kovai Medical Center and Hospital NOSOCOMIAL PNEUMONIA Intubation for mechanical ventilation increases the risk for pneumonia 3x to 21x ! AJRCCM 2002; 165:867-903 Department of Critical Care Medicine Kovai Medical Center and Hospital Colonization Aspiration MRSA* VAP Department of Critical Care Medicine Kovai Medical Center and Hospital GOAL • Suctioning • Humidification • Aerosol delivery Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING SUCTIONING Introduction • Commonly done procedure in a patient on Mechanical Ventilation. • Includes preparation, Suctioning event and follow up care. • Closed or Open Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING NEED FOR SUCTION • Saw tooth pattern on FV loop Inspiration Flow (L/min) • Increase PIP in VCV • Decrease SPo2 Volume (ml) • Visible secretions in airway • Patients inability to generate effective cough. • Acute Respiratory distress • Suspecting aspiration of gastric secretion or upper airway secretions Department of Critical Care Medicine Kovai Medical Center and Hospital Expiration Normal Abnormal SUCTIONING SUCTIONING - PREPARATION Suction Catheter • More influence on lung volume loss than suction pressure. • Diameter of the catheter should not exceed > half ID of ET Tube. Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING SUCTIONING - PREPARATION • Pre oxygenation • 100% : Setting the Fio2 O2 Enrichment programme Manual Breath not recommended • Suction : Checked • Negative Hg : 150mm.hg for adults. 80-100mm.hg for neonates Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING SUCTIONING Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING SUCTIONING Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING SUCTIONING Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING SUCTIONING Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING SUCTIONING Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING SUCTIONING Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING SUCTIONING Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING • Don’t apply suction as you go in • Don’t disconnect for suction > 15 sec • Don’t use soda bicarbonate or saline • On need basis • Pre-oxygenation must • Should be done with sterile precautions Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING SUCTIONING CLOSED SUCTION • In hypoxic pts on high PEEP • MDR infections - Open TB, Viral Infections (HCW protection) • Does not reduce VAP • OPEN SUCTION OK IN MOST PATIENTS Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING COMPLICATIONS OF SUCTION • Decreases FRC • Atelectasis • Hypoxemia • Tissue trauma • Bronchospasm • Colonization of lower airways • Increases BP & Arrhythmia • Increases ICP Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING HUMIDIFICATION Definition: • Absolute Humidity : Density of moisture (water vapour) per unit volume of air, expressed usually as kilogram per cubic meter (kg/m3). • Relative Humidity : Absolute Humidity Maximum capacity Department of Critical Care Medicine Kovai Medical Center and Hospital 100 SUCTIONING HUMIDIFICATION Introduction • Normal breathing upper airway does the function of warm, humidification, and filtered inspired gases. • Lower airway also contribute but less effective. • During exhalation, upper airway reclaim most of the heat and moisture added during inspiration. • Normal daily respiratory tract loss 1470J of heat and 250ml of H20. • Normal upper airway remarkably effective at extremes of temperature. Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING HUMIDIFICATION Introduction • Moisture output for HH – 33mg H20 / L • AARC - Required moisture output to be determined relative to application and duration of use. • Moisture output based – Insp Time RR TV Temperature Rebreathing Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING HUMIDIFICATION Isothermic Saturation boundary • Point of which gases reaches alveolar condition is known as Isothermic Saturation boundary. • Under normal condition - 4th or 5th subsegmental bronchi. • Post Intubation – shifted down, less effective. Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING HUMIDIFICATION Types • High flow Humidifier - Bubble through - Flow over • HME Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING HUMIDIFICATION High flow Humidifier Consist of • Heating elements • Water reservoir • Temperature control unit • Gas - liquid interface Capable of providing wide range of temperature and humidification. Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING HUMIDIFICATION High flow Humidifier • Water level maintained - Manual fill - Auto fill ( float) • Servo controlled • Alarms • Heated wire circuit available • Circuits with water trap Department of Critical Care Medicine Kovai Medical Center and Hospital HEATED HUMIDIFIER • Gold standard • Raining is a problem • Cannot be maintained as a closed system • Condensate should be drained away from pts to water trap • Newer generation less raining & can be maintained as a closed system (AUTOFILL) • VAP rate > HME Department of Critical Care Medicine Kovai Medical Center and Hospital HEATED HUMIDIFIER • Gold standard • Raining is a problem • Cannot be maintained as a closed system • Condensate should be drained away from pts to water trap • Newer generation less raining & can be maintained as a closed system (AUTOFILL) • VAP rate > HME Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING HUMIDIFICATION HME • Hygroscopically treated Devices (HHME) • HHME & Bacterial Filter - HHMEF • Aluminium insert with fibrous element • Polypropylene insert with hygroscopic channel usually ca or lithium chloride for moisture conservation. • Filter material - spun Polypropylene, is electrostatically charged attracts and traps airborne particles. Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING HUMIDIFICATION - HME Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING HUMIDIFICATION HME • Increases Resistance - <3.5cm.H2O • Increases Resistance when occluded with blood or secretions • Disconnect during Aerosol devices • Visual inspection - Manufacturing defect • Dead space - Minimal Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING HUMIDIFICATION HME Desirable Qualities • Moisture output - 28 mg H2O/L • Dead space - 50ml • Resistance <2.5cm. H2O • Always involves net loss of heat and temperature. Department of Critical Care Medicine Kovai Medical Center and Hospital HME DON’T USE 1. Hypothermia 2. Thick secretions 3. Bloody secretions Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING HUMIDIFICATION - ALGORITHM Department of Critical Care Medicine Kovai Medical Center and Hospital SUCTIONING HME Vs HUMIDIFIER No difference in terms of • ICU Mortality • Length of ICU stay • Duration of Mechanical Ventilation • Episodes of airway occlusion Department of Critical Care Medicine Kovai Medical Center and Hospital FACTORS AFFECTING DRUG DELIVERY DURING MV • Position of patient • Aerosol generator & Configuration in ventilator circuit • Aerosol particle size • Ventilatory parameters Department of Critical Care Medicine Kovai Medical Center and Hospital INHALED MEDICATIONS EMPLOYED IN PATIENTS RECEIVING MECHANICAL VENTILATION • Bronchodilator • Beta-agonist (albuterol, metaproteronol, fenoterol) • Anticholinergic (ipratropium bromide) • Prostaglandin (alprostadil, prostacyclin, iloprost, treprostonil) • Mucolytics (acetylcysteine) • Proteins (Pulmozyme) Department of Critical Care Medicine Kovai Medical Center and Hospital INHALED MEDICATIONS EMPLOYED IN PATIENTS RECEIVING MECHANICAL VENTILATION • Surfactant (Exosurf) • Antibiotics • Antibacterial (aminoglycosides) • Antiviral (Ribavirin) • Antifungal (amphotericin) • Corticosteroids (beclomethasone; budesonide) • Miscellaneous Department of Critical Care Medicine Kovai Medical Center and Hospital OPTIMAL TECHNIQUE FOR DRUG DELIVERY BY PMDI IN VENTILATED PATIENTS • Review order, identify patient, and assess need for bronchodilator. • Suction endotracheal tube and airway secretions. • Shake pMDI and warm to hand temperature. • Place pMDI in space chamber adapter in ventilator circuit. • Remove HME. Do not disconnect humidifier. • Coordinate pMDI actuation with beginning of inspiration. • Wait at least 15 seconds between actuations; administer total dose. • Monitor for adverse response. • Reconnect HME. • Document clinical outcome. Department of Critical Care Medicine Kovai Medical Center and Hospital OPTIMAL TECHNIQUE FOR DRUG DELIVERY BY JET NEBULIZER IN VENTILATED PATIENTS • Review order, identify patient, and assess need for bronchodilator. • Suction endotracheal and airway secretions. • Place drug in nebulizer to fill volume of 4 ml to 6ml. • Place nebulizer in the inspiratory line 18 inches (46 cm) from the patient y-piece. • Turn off flow-by or continuous flow during nebulizer operation. • Remove HME from circuit (do not disconnect humidifier). • Set gas flow to nebulizer at 6 L to 8 L per minute. • Use a ventilator if it meets the nebulizer flow requirements and cycles on inspiration, or • Use continuous flow from external source. Department of Critical Care Medicine Kovai Medical Center and Hospital OPTIMAL TECHNIQUE FOR DRUG DELIVERY BY JET NEBULIZER IN VENTILATED PATIENTS • Adjust ventilator volume or pressure limit to compensate for added flow. • Tap nebulizer periodically until nebulizer begins to sputter. • Remove nebulizer from circuit, rinse with sterile water and run dry, store in safe place. • Reconnect humidifier or HME, return ventilator settings and alarms to previous values. • Monitor patient for adverse response. • Assess outcome and document findings. Department of Critical Care Medicine Kovai Medical Center and Hospital AEROSOL DELIVERY • MDI preferred • MDI adaptor placed 18cm from ‘Y’ of inspiratory limb • May use collapsible chambers • Actuation timed to end of expiration • Remove HME in place Department of Critical Care Medicine Kovai Medical Center and Hospital HAND HYGIENE Department of Critical Care Medicine Kovai Medical Center and Hospital HAND HYGIENE • Intubation: If elective standard hand wash + sterile gloves If emergent hand rub + sterile gloves • Suctioning : Alcohol hand rub before and after procedure Clean gloves • Bronch’: Surgical hand / forearm scrub Full sterile field, gown and gloves • Always consider masks, splash guards and eyewear. • Full chlorhexidine hand wash if accidental exposure to secretions Department of Critical Care Medicine Kovai Medical Center and Hospital FAST HUG F …………. Feeding A …………. Analgesia S …………. Sedation T …………. Thrombo prophylaxis H ……….... Head-of-bed elevation U …………. Ulcer prophylaxis G …………. Glucose control Department of Critical Care Medicine Kovai Medical Center and Hospital DON’TS • Paralyze endlessly to calm down • Daily CXR in stable pts • Don’t put soda bicarb to loosen the secretions • Change ET tube or ventilator circuits routinely • Don’t make them starve • Don’t sent ET or suction catheter tip – c/s • No prophylactic antibiotics Department of Critical Care Medicine Kovai Medical Center and Hospital TRAINING COURSES OFFERED AT KMCH ICU Indian Diploma in Critical Care Medicine Conducted by Indian Society of Critical Care Medicine Indian Fellowship in Critical Care Medicine Conducted by Dr MGR Medical University, BSc Respiratory Therapy Conducted by Dr MGR Medical University Post Graduate Dip. In Critical Care Nursing Conducted by Christian Medical Association & INC Department of Critical Care Medicine Kovai Medical Center and Hospital ICU TEAM TEAM - Together Everyone Achieves More Thank You