End-of-life Issues in the ICU Dr. Nehad Nabeel Al-Shirawi MRCP(UK), EDIC, Saudi Fellowship in ICU Intensivist / Pulmonologist بسم هللا الرحمن الرحيم ‘And whosoever saves a life, it is as if they have saved the whole of ’humankind علَى َبنِي إِس َرائِي ْل َ أَ َّن ْه ك َك َتب َنا َْ {مِنْ أَج ِْل َذلِ َْ ض َف َكأ َ َّن َما سادْ فِي األَر ِ ْ سا ِب َغي ِْر َنفسْ أَوْ َف َ َمن َق َت ْل َ َنف ً ِيعا َو َمنْ أَحْ َياهَا َف َكأ َ َّن َما أَحْ َيا َق َت ْل َ ال َّن َْ اس َجم ً ت ث َّْم إِنَّْ اس َجمِي ًعا َولَ َقدْ َجاءتهْمْ رسل َنا ِبال َب ِّيَْنا ِْ ال َّن َْ ض لَمس ِرفونَْ} ك فِي األَر ِ ْ َكثِيرْاً ِّمنهم َبعدَْ َذلِ َْ Qur’an 5:32 Presentation Outline • • • • • • Problems with DNR decision in our societies Definitions When to consider DNR Islamic Point View of DNR My Study Conclusions Problems with DNR Decisions in Our Societies Problem # 1 Ignorance Many people are so ignorant to understand the meaning of “DNR” and futility of treatment. Problem # 2 Misconceptions Regarding Death Misconceptions among most of the population leading to lack of understanding and acceptance of “DEATH”. !!!!!!!! )ْ(يحيْالعظامْوهيْرميم Problem # 3 Misconceptions Regarding Role of HCP Confusion about our role as health care providers (save lives at any cost) ْ(احناْعملناْإ ّليْعلينا )والباقيْعليْهللا DNR Guideline: How Much of Islamic Point-View • Guidelines are necessary to identify the key ethical and legal issues that govern DNR decisions • The guidelines provide a framework to support physician in 1. Making DNR decisions 2. Communicating them effectively • Islamic point-view should be considered ALL the time Definitions DNR • Instructions that the patient should not receive cardiopulmonary resuscitation (CPR) in the event that he / she suffers a cardiac arrest, usually in the hospital • Do not intubate, do not defibrillate, no medications Life – Prolonging Measures • • • • • Intravenous Fluids Nasogastric tube feeding Dialysis Vasopressors Mechanical ventilation Medical Futility • When CPR and other critical care efforts have no reasonable chance of prolonging life or providing benefit to the patient – i.e. they are futile – Discharge to home intact – Pain / symptom free life – Full awareness of the surroundings Euthanasia • Euthanasia: comes from the Greek “Eu-thanatos” which means “ an easy or good death” • Killing the patient for their own benefit Death • Death has several consequences Medical Legal Religious Socioeconomic 1. 2. 3. 4. (خروج الروح من الجسد) • Death = body – spirit • قال هللا تعالى ( :قل يتوفاكم ملك الموت الذي و ّكل بكم ثم إلى ربكم ترجعون ) السجدة 11 • ( ويسألونك عن الروح قل الروح من أمر ربي وما أوتيتم من العلم إال قليال) االسراء 58 Death • Medical Definition: The irreversible cessation of all vital functions especially as indicated by permanent stoppage of the heart, respiration, and brain activity • In many countries : Brain Death = Death • In Islamic countries – disagreement When to Consider DNR ? When to Consider DNR ? 1. CPR is unlikely to useful (Futile) 2. CPR is not in accord with a valid advance directive 3. CPR is not in accord with a competent patient’s recorded and sustained wishes 4. Resuscitation is likely to be followed by a length and quality of life that would not be in the best interest of the patient (pain, lack of awareness) Emergency Situations • In emergencies, there will rarely be time to make a proper assessment of the patient’s condition and the likely outcome of CPR and so attempting CPR will usually be appropriate • Health professionals will make all reasonable efforts to attempt to revive the patient in the event of cardiac or respiratory arrest It is Important to Explain that: • No CPR does not mean no other treatment • No CPR does not mean withdrawal of mechanical ventilator, etc • No CPR does not mean “Mercy Killing” Islamic Point-View What’s Unique about Ethics in Islam What is Moral in Islam is Always Legal (Halal) Human Life But if one saves a life, it shall be as if he saved all mankind.” Qur’an 5:32. “Every soul shall taste death” Qur’an 3:185. Death: International Collective Of Islamic Jurists And OIC. Amman, Jordan 1986 • Declaration of death: – Heart and breath have stopped and the condition is irreversible OR – Mental function has ceased and the condition is irreversible – Responsibility of the physician ١٣ -٨ ) الصادرعن مجلس مجمع الفقه اإلسالمي المنعقد في دورة مؤتمره الثالث بعمان من٥ ( القرار رقم في دورة مؤ تمره٨٨ / ٠٨ /٤ ) د١ ( وقراره رقم، ١٩٨٦ تشرين األول/ أكتوبر١٦- ١١ / ه١٤٠٧ صفر ١٩٨٨ شباط/ فبراير١١ -٦ الموافق/ ه١٤٠٨ جمادى اآلخرة٢٣ - ١٨ الرابع بجدة في السعودية من Time of Death • Time of Death = Complete cardiopulmonary arrest after withdrawal • المريض الذي ركبت على جسمه أجهزة اإلنعاش يجوز رفعها إذا تعطلت جميع وظائف دماغه تعطالا نهائيا ا وقررت لجنة من ثالثة أطباء اختصاصيين خبراء أن التعطل ال رجعة فيه ،وإن كان القلب والتنفس ال يزاالن يعمالن بفعل األجهزة المركبة ،لكن ال يحكم بموته شرعا ا إال إذا توقف التنفس والقلب تاما بعد رفع األجهزة في قرار المجمع الفقهي اإلسالمي التابع لرابطة العالم اإلسالمي في دورته العاشرة المنعقدة في مكة المكرمة 1408هـ 4 Ethical Principles 4 Ethical Principles in Islam Principle of maslahah (Self and public interest) is to address the needs of humankind and confers the welfare of most people. The principle of la darar wa la dirar (a person must not harm himself or someone else) – prohibited to cause a loss to another person The Major Islamic Ruling Principles The Sharia Law System Arabic Do it Not do it Fard Wajeb Reward Punishment Mustahab Mandub Reward No Punishment Mubah Halal No Reward No Punishment Discouraged (Disliked) Makruh Manboth No Punishment Reward Forbidden (Prohibited) Haraam Mahd’ur Punishment No Reward Category Obligatory (Prescribed) Recommended (Desirable) Permitted (Allowed) 28 Is Medical Treatment Necessary? • Definite: o o o The desired results are achieved without fail e.g. stop bleeding to sustain life Mandatory )(واجب • Probable/Expected: o o o The desired results are often achieved but not always e.g. many medical treatments Sunnah )(سنه • Imagined: o o o The desired results are not a realistic expectation e.g. some medical treatments Permissible )(مباح Resuscitation In Islam • Two opinions (مندوب)= حكم التداوي 1. Recommended (فرض كفاية) = إنقاذ الروح 2. Obligatory • Most people agree on second opinion because • المريض ال اختيار له في هذه الحال فال يمكن إجراء حكم التداوي على مسألة اإلنعاش • المريض في في حالة خطرة وحاجته ألجهزة اإلنعاش أصبحت أمراا ضروريا ا كحاجته للطعام والشراب بحيث لو تركه فقد عرض نفسه للهالك Fatwa # (12086) Dated (1989) by the Saudi Committee for Fatwa & Islamic Affairs Fatwa # (12086) Dated (1989) by the Saudi Committee for Fatwa & Islamic Affairs Permitted (Mubah) Do Not Resuscitate order: when the treatment becomes futile. Withdrawal or withheld therapy is permitted in brain death. Forbidden (Haraam) Active Euthanasia: Passive Euthanasia: Patient should be provided with food, drink, nursing, and relief from pain until death. Suicide Murder. "take not life which Allah has made sacred" Qur’an 6:151. What About Withdrawal ? • In patients with deep coma/persistent vegetative state –forbidden (Haram) by most authorities • In Brain Death – many authorities said is allowed (Halal) ،١٩٨٧ مجمع الفقه اإلسالمي الثالث التابع لمنظمة المؤتمر اإلسالمي المنعقد في عمان باألردن عام ه١٤٠٨ /٢ / ٢٤ وفتوى المجلس الفقهي التابع لرابطة العالم اإلسالمي في دورته العاشرة في ? What About Withdrawal • إذا قرر ثالثة أطباء متخصصون فأكثر رفع أجهزة اإلنعاش عن المريض الموضحة حالته في السؤال األول (حالة عجز شديد -مثل :الشلل الدماغي ، ومصاب بتخلف عقلي شديد) -فإنه يجوز اعتماد ما يقررونه من رفع أجهزة اإلنعاش ،ولكن ال يجوز الحكم بموته حتى يعلم ذلك بالعالمات الظاهرة الدالة على موته ،أما موت الدماغ فال يعتمد عليه في الحكم بموته • إذا قرر األطباء المختصون رفع األجهزة في الحالة المذكورة في السؤال األول ، فإنه ال يلتفت إلى معارضة األهل • إذا غلب على ظن الطبيب المختص أن الدواء ينفع المريض وال يضره أو أن نفعه أكثر من ضرره ،فإنه يشرع له مواصلة عالجه ،ولو كان تأثير العالج مؤقتا؛ ألن هللا سبحانه قد ينفعه بالعالج نفعا مستمرا خالف ما يتوقعه األطباء . [ قرار هيئة كبار العلماء) رقم ( ) 190وتاريخ 1419/ 4/ 6هـ My Study My Study • Questionnaire-based study • 12-questions questionnaire distributed to physicians at SMC • Total sample size 152 physicians Basic Characteristics Characteristic Number Percent Age < 40 years 103/144 71.5 Age ≥ 40 years 41/144 28.5 Male 109/152 71.7 Female 43/152 28.3 Muslims 140/150 93.3 Other Religions 10/150 6.7 Sub-specialty Total Number = 135 51.1% 25.9% 17.7% 5.3 % Professional Level Answer to Policy Questions DNR Do you Feel Comfortable or at Ease when Talking to Relatives about DNR?? Do you Feel Comfortable or at Ease when Talking to Relatives about DNR?? Majority of females don’t feel comfortable )P value < 0.05) Withdrawal in Brain Dead There is a significant number of physicians Who said NO !!!! Why not Withdrawing in Brain Dead ? Persons Involved in DNR Decision The main persons involved in DNR decisions are the Caring Team and consultant Reasons for Making DNR Conclusions Conclusions • There are many misconceptions concerning DNR decisions among health care professionals • In the era of resource utilization and scares ICU beds, making DNR decisions might seem necessary if the treatment is futile • A clear Law is needed to regulate this matter