Geriatric Urinary Incontinence Alexandra F. Suslow MD % of Geriatric aged population 1970 --->9.9% 1984 -->11.5% 1997 -- >13.1% 2020 --> 20% Life Expectancy A child born in 1900--> <40 years A child of the late 60’s--> 68.5 years A child of the 90’s---> 72 years A child of the Millenium--> >75 years Reported prevalence of UI 15-30% of community dwellers (ie” independent seniors”) 30% of elderly in acute care > 50% of long term care facilities (eg. NH) DON’T ASK DON’T TELL Myths and Facts It is a normal part of aging It is not a medical issue “I’m not incontinent,I just have “accidents” There is nothing to do about it It’s just a minor inconvenience It is abnormal at any age(other than infant) It is a medical issue, like HTN or DM Any involuntary loss is incontinence Alleviation and occsl. cure are possible THINK AGAIN!!! Problems due to UI Major Medical Problems Major social issues Major economic issues Medical Issues Pressure ulcers leading to infections and sepsis Perineal rashes Urosepsis Increased risk of falls and fractures with subsequent increase of morbidity/mortality Social issues “ Cultural conditioning leading to stigmatization,social isolation, depression, and increased Psychological Morbidity” (Umlauff et. all) Economical Issues, general Cost of Rx of associated symptoms (eg rashes and pressure sores) Routine care costs( supplies,laundry) Direct Medical Cost: Physician and Diagnostics Economical Issues, Nursing Home Marked increase in cost due to the increase in necessary nursing care (frequent changing of pt and linens) and due to increase utilization of supplies and ancilliary services Estimated cost $3 billion Breakdown of costs Diagnostic/ medical $6.0 0.2% Treatement surgical 1.2 0.04 Treatement Pharmac. 0.7 0.02 Routine care c catheter 104.7 3.2 Routine care s catheter 19,061 58.4 Sequelae (uti,falls etc) 15.71 4.8 NH admissions due to UI 1087.7 33.3% Total NH Cost Us$ 3.26 Billion (cost in 1987) Cost in Community Dwellers Estimated to be about $7 Billion, including costs of supplies, outpatient visits, short term hospitalizations etc. GRAND TOTAL • $10 billion . • Adjusted to 1997-->$16 billion • (more than cost of CABG/Dialysis combined) Continence Determining Factors Intact lower urinary tract anatomy and function Adequate Mobility Motivation Mentation Manual dexterity Age Related Changes in LUT Women: postmenopausal decrease in oestrogen leading to tissue atrophy,prolapse, changes in vaginal flora--->incr. risk of UTI Men:Prostatic changes leading to urodynamic obstruction and the sequelae thereof Age related changes cont’d changes in both genders Changes in neurotransmittor balance and immune response. Anatomic changes such as trabeculation, diverticulae, decreased elasticity Involuntary detrussor contractions Malnutrition, dehydration leading to fecal impaction and incr. risk of UTI Medications Diuretics--.polyuria,frequency,urgency Anticholinergics:retention,impact. overflow alpha-adrenergic blockers:urethral relax alpha agonists,beta agonists, Ca channel Blockers:urinary retention Ace inhibitors: cough exacerbation Medications, cont’d Narcotics: retention, impaction, sedation, delirium Psychotropics: anticholinergic effect, sedation, rigidity Lithium: polyuria,frequency ETOH: polyuiria,urgency, sedation Classification of UI Transient incontinence “Functional “ incontinence Established incontinence --LUT causes Transient Incontinence D elirium I nfection symptomatic UTI A trophic urethritis P harmacological agents Side effects of Specific Meds Anticholinergic agents Frequent in prescription and OTC meds( antihistamines) Causes overt and clinical retention---> faster attainment of capacity--> exacerbation of Detrussor overactivity Aggravates leakage in stress inc. Causes dry mouth-->polidypsia--> increase UOP Side Effects of Specific Meds Alpha adrenergic blockers Found in many anti hypertensive meds Block receptors in the bladder neck--> decreased tone-->agrravation of stress incontinence Side Effects of Specific Meds ACE INHIBITORS Often prescribed for HTN, CHF Tend to exacerbate chronic cough--> increase of stress incontinence Transient Incontinence D elirium I nfection symptomatic UTI A trophic urethritis Pharmacological agents Psychiatric causes Excess UOP Restricted mobility Stool impaction Established Incontinence: LUT causes of UI overactivity (“Urge Inc.”) Stress incontinence Overflow incontinence Detrussor Goals of the Work-up R/o and treat transient causes R/o uncommon causes : CNS,CA,stone Determine the type of established UI Complaints in Detrussor Overactivity Presence or absence of “warning” Frequency Nocturia Causes of Nocturia Volume related:Excess intake, diuretic use, metabolic/endocrine, fluid overload, meds LUT Related: detrussor instability,sensory urgency, prostatic changes Only 22% of incontinent patients had pelvic/rectal exam preformed by their Doctor (Shame on us!!!) Physical Exam Baseline Exam (HEENT--->Extremities) Expanded Neurological Exam Stress Test PVR Urodynamic tests: cystometry Cystoscopy False Results of Stress test False Pos: Urge during the test False neg: – Stressor not strong enough – Bladder not full – Cystocele kinking the urethra Management of Detrussor Overactivity Bladder Retraining Prompted Voiding “ Just Say No” to Surgery Pharmacological management Drugs For DO Others: Flavoxate, Ca chnl Blk, B-block/agonist Imipramine Doxepine Anticholinergics • Propantheline (Pro-Banthine) • Dicyclomine (Bentyl) • Oxybutinin (Ditropan) • Tolterodine (Detrol) Management of Stress Incontinence Surgical Pharmacological Pelvic mm.Strengthening • Kegel excercises • Vaginal Cones • Electric Stimulation Surgical Interventions in Stress Incontinence Perurethral injection of teflon Artificial Sphincter Colposuspension Management of Overflow Incontinence Blockage: • Conservative Rx • alpha antagonists • 5-alpha reductase inhibitor • Prostatectomy Underactive Bladder: • Decompression • Catheterization • Betanechol Diapers and Pads Protect Environment Maintain comfort and dignity of patient Special Thanks The Lord: For everything Pam S.: For her help (and patience) in the Library Dr Houghton:For his help and advice for the presentation Stacy and Julie: The Fairy Godmothers of the Residents Dr Wells-Padron PharmD for the Nutrasweet All who had to listen to the presentation over and over and over again