Relevant Cerebro-Vascular Anatomy for Carotid Intervention Ricardo A Hanel, MD Elad Levy, MD L N Hopkins, MD Cerebrovascular Anatomy Why should I learn it For CAS ? Basic anatomy and collateral circulation is enough Always obtain baseline films for comparison Knowing the anatomy helps avoid complications 2 ICA’s &VA’s carry 20% of Cardiac OP ICA’s fixed from skull base to supraclin ICA VA’s fixed in vertebral foramen Carotid artery interventions Clinical applied Anatomy will influence: – The best therapeutic option (CEA x CAS) – The best Access (femoral, brachial, direct) – Device selection – Complication avoidance – Complication management Aortic Arch Views Arch angio to assess access LAO 30-45 degrees best Multiple views…origin ds RAO 20.. R subclavian from RCCA Carotid Artery Petrous Carotid Variability enormous Bifurcation C1 – T2 Best working view… lat/obl Bony landmarks … -Unsubtract Skull Base ICA ECA Cervical Carotid Views Obtain AP, Lateral and Oblique projections Clear ICA origin from ECA Evaluate for dissection, thrombus, calcium, kinks Measurements using NASCET criteria – 1 - (Stenosis diameter/Nontapered segment diameter) Cervical ICA “No Branches” Hi flow…Don’t overdilate! Fixed near skull base Carotid Sinus What is this?? Where to put the filter? Connections ICA to VA Pcomm Otic Primitive trigeminal Hypoglossal Pro atlantal ECA anatomy ECA Branches 1. Key source of collateral 2. Anastomoses to ICA or VA 3. Stent will not occlude ECA When handling the ECA remember… EC-IC anastomosis common May not be seen on angiogram With major vessel occluson these anastomosis may hypertrophy ECA embolus may cause stroke BE AWARE! The GuardWire® Balloon Protected Procedure Pre-intervention Cine E. Deflate the GuardWire® protection balloon and evaluate final result Post-intervention Cine The GuardWire® Balloon Protected Procedure SVG with covered stent sample Carotid stenting sample Complication: Visual Loss due to retrograde embolization of retinal arteries via ECA branches ICA Anatomy Supraclinoid ICA Petrous ICA Ophthalmic a Cavernous ICA Base of Skull Onward and Upward… ICA becomes fixed 2-3mm proximal to skull base Petrous ICA up to supraclinoid ICA fixed in bone/ligamentous/dural encasement Intracranial vessels more mobile but fragile and easily damaged/ruptured Skull Base From Below ANT •Horizontal Petrous ICA ICA Entrance Post Skull Base From Above Ant Horiz Petrous ICA Post Petrocavernous ICA Side View - Right Cavernous Ascending Petrous Cavernous – Supraclinoid ICA Anterior Medial Loop Horizontal Cavernous ICA Supraclinoid ICA Post Communicating Perforators Quiz … What is this?? Although uncommon, carotid-basilar anastomoses, other then PComm, may occur: – Persistent trigeminal artery (0.25%) From Cavernous ICA to basilar Ascending Petrous ICA Primitive Trigeminal Intracranial Vascular Anatomy After giving origin to the Ophthalmic A, PComm and Ant Choroidal artery the ICA finally bifurcates into the Anterior Cerebral Artery - ACA and Middle Cerebral Artery – MCA Intracranial Vascular Anatomy A Must….pre op AP and Lateral Angio Have them handy!!!! Variations are the Rule Many variations of these vessels Always have pre op films to compare in case of trouble And always do a baseline Neuro exam pre op 3 M-2 branches MCA embolus ????? The Circle of Willis Connection between: – Carotid-basilar system – Rt/Lt side – Vessels involved: ACAs & AComm ICAs & PComms PCAs Basilar T/F : The Circle is Always Intact ?? Pcomm Acomm Pcomm Pcomm The Circle of Willis The Circle of Willis is complete in only 3040% of the cases Many variations Hypoplasia of one of the A-1 segments of the ACAs… Or ICA stenosis??? A-1 What is this? MCA & ACA Anatomy ACA MCA ACA A-2 Acomm A-1 M-1 M-2 MCA Where is the ACA ? MCA … Many Variations ACA Anatomy A-2 A-2 PComm A-1 Variations, variations, variations … Message ??? Vertebral Artery Anatomy Rich Muscular Collateral Variations, variations, variations … A complete diagnostic angiogram with clinical/anatomical correlation should be performed and available before any major intervention ICA Occlsion R ICA Occl with Collateral …Circle of Willis L Carotid R Vertebral R ICA Occl with Pial Collateral R ICA Occl with Vertebral Collateral to MCA PComm ICA Occlusion with Ophthalmic Collateral Ophthalmic To ICA L CCA R ICA Occl with Ophthalmic and Pial Collateral Vascular Territories Normal Angiogram Capillary Phase Capillary Phase Pre Embolus Post Embolus Complications Interventional procedure going uneventfully until….. Pt agitated & hemiparetic What is this? What should you do? Complications Intracerebral Hemorrhage ACA and MCA spread…Barrel Shift Hemorrhage CT Scan You DO NOT need to angiographically visualize extravasation to have bleeding. What is This ? Proceed with CAS ?? And this ? …And This ?? Dangerous Anatomy Elderly Patient Stay Away!! “Corkscrew” Carotid Trouble …for sure! Judgement!! Backing out is OK Causing a Stroke is Not Roubin Conclusion… Catheter skills + Anatomic Knowledge = Better results