Dysphagia นพ.โกสิ นทร์ ชัยชำนำญ Ent Objectives Normal physiology Dysphagia Definition Cause and classification History taking,physical examination and investigation Disease Normal physiology 4 stage Oral preparatory stage Oral stage Pharyngeal stage Esophageal stage Normal physiology Oral preparatory stage Prepare food for swallow Mechanism of action 1.lip closure to hold food in mouth anteriorly 2.tension in labial&buccal musculature to close Ant&Lat sulci 3.rotatory motion of jaw for chewing 4.lateral rolling motion of tongue position food on teeth during mastication – most important 5.bulging forward of soft palate to seal oral cavity posterior and widen nasal airway Oral preparatory stage 1.Muscle of facial expression (VII) –oral sphincter Orbicularis oris – sphincter of lip – compress lip@flatten cheek Buccinator Oral preparatory stage 2.Muscle of mastication (V) – jaw movement pterygoid – open@grinding Lateral Masseter jaw – close – open@A/P move Temporalis pterygoid – close@grinding Medial Oral preparatory stage y 3.Tongue muscle – down soft palate@up BOT Palatoglossus(X) Genioglossus(XII) elevate BOT – Hyoglossus(XII) depress -- Oral preparatory stage er Time : depend on type of food Normal physiology Oral stage Move food from front oral cavity to pharynx Mechanism of action ○ 1.Upward&backward by midline& Lat margin of tongue – most important ○ 2.Backward by tension in buccal musculature ○ 3.trigger swallowing reflex (locate at anterior pillar) Oral stage swallow buccal musculature tongue Styloglossus Hyoglossus muscle muscle Oral stage swallow trigger zone at anterior pillar Oral stage ri swallow trigger swallowing reflex sensory impulse at CN IX Oral stage swallow Tractus solitarius nucleus/ Solitary tract nucleus trigger swalling reflex sensory impulse at CN IX (& Sup. Laryngeal nerve) Oral stage swallow nucleus ambiguus nucleus ambiguus to motor neuron of CN X at pharynx Oral stage swallow nucleus ambiguus nucleus ambiguus to motor neuron of CN X at pharynx Oral stage er Time : take 1 second Pharyngeal stage Move food from pharynx to esophagus Mechanism of action 1.velopharyngeal closure (prevent backflow of material up nose) 2.tongue base retraction (propel bolus through pharynx) 3.pharynx contraction (clear redisue through pharynx) 4.larynx elevate and closure (airway protection) 5.cricopharyngeal opening (allow bolus to pass into esophagus) t Pharyngeal stage swallow 1.tongue Styloglossus Hyoglossus muscle muscle Pharyngeal stage swallow 2.Levator @ Tensor palatini Tensor palatini Levator palatini Pharyngeal stage swallow 3.pharyngeal constrictor muscle Superior Middle Inferior Pharyngeal stage swallow 4.aryepiglottic fold/true vocal fold /false vocal fold AEF FVF/TVF Pharyngeal stage er Time : take less than 1 second (not vary with age and gender) Esophageal stage Close UES Body of esophagus Outer -> longitudinal ,Inner -> circular Peristalsis primary peristalsis : ○ upper 1/3 striated & transitional zone ○ mix voluntary & involuntary secondary peristalsis : ○ lower 2/3 smooth ○ Involuntary Open LES Esophageal stage er Time : take 8 to 20 seconds (depend on food influence by peristalsis&gravity) Dysphagia History Onset & Site Cough or choke or food coming back through your nose Liquid or solid or both Liquid and solid motility disorder Solid progress to liquid benign or malignant stricture Progression Dysphagia History Other symptoms Loss of appetite,weight loss ,N/V regurgitation,heart burn,weakness, hematemesis,pain Medical problems DM, HT, cancer Hx. Of surgery Dysphagia History Hx. Of radiation Medications In children Feeding Growth Development Dysphagia Physical examination Complete examination Head and neck Mass Thyroid Lymph node Salivary gland Oral mucosa Gag reflex, Cough reflex Dysphagia Investigation Procedure to evaluate -- major 1.Fluoroscopy 2.Endoscopy 3.Manometry 4.Ultrasonography Dysphagia Fluoroscopy Barium swallow conventional barium swallow modified barium swallow Dysphagia Fluoroscopy Modified barium swallow Gold standard Examine oral cavity & pharyngeal swallowing Ba(1/3 teaspoon per swallow) & vary food consistency Seated upright in normal eating position Dysphagia Fluoroscopy Modified barium swallow View in lat. plane with fluoroscope tube Focus on lips & C7th Dysphagia Fluoroscopy Modified barium swallow Purpose restore oral intake as quickly ○ 1.define oral&pharyngeal disorder during swallow ○ 2.identify aspiration of any food consistency ○ 3.assess speed of swallow to determine adequate nutrition ○ 4.assess effect of Tx eg.postural change ,heightened sensory input ,Tx procedure (swallowing maneuvers) Dysphagia Fluoroscopy convention barium swallow Examine anatomy & motility esophagus Ba(a cup of barium)(250 cc)swallow repeatedly Lies in supine position View in anteroposterior plane Dysphagia Fluoroscopy Dysphagia Achalasia(failure to relax) (bird's beak appearance) A:Contrast penetrate laryngeal vestibule within boundary of vocal cord B:aspirate tracheobronchial tree Dysphagia Endoscope Via transnasal placement of flexible fiberoptic scope Can not examine oral stage & during swallow May be identified residual food in pharynx after swallow Dysphagia Manometry Used examine esophageal peristalsis & function of UES & LES Swallow soft tube contain 3 pressure sensor First register --- UES Second register – body of esophagus Third register – pressure in LES No information on aspirate or function in oral cavity or larynx Dysphagia Ultrasonography Used assess anatomy & physiology of tongue during swallowing (oral stage ) Can not examine pharynx or larynx because of skeletal interference Dysphagia Other investigate Plain film : film lateral neck(soft tissue technique) -- FB,Infection CT/MRI 24 hrs.pH monitoring วัดภาวะกรดด่ างในหลอดอาหาร คน ปกติจะมี pH<4 ที่เหนือกล้ามเนื้อหูรดู ล่าง 5 cm ไม่เกิน 1 hr./วัน Dysphagia Other investigate Scintigraphy Nuclear medicine test Swallow several selected bolus of radioactive material Gamma camera detect amount radiation passing Oropharyngeal anatomy not visible Aspiration – two trial material swallows ○ One to esophagus ○ Another to airway The end…