OLYMPUS EUS CONTENTS • • • • • • Diagnostic EUS Sampling & Interventional EUS EBUS Ultrasound Processors Needles for EUS-FNA & EBUS-TBNA Summary DIAGNOSTIC EUS GF-UE160/260-AL5 • Full 360 degree Electronic Radial Array for comprehensive imaging of GI tract and adjacent structures • • • • • Superior handling characteristics Colour / Power Doppler capability Tissue Harmonic Echo Contrast Harmonic Echo Up to 12MHz imaging in conjunction with EU-ME1 SUPERIOR HANDLING • Forward-oblique optic design, supports: • Short rigid portion at distal tip • Facilitates safe intubation and easy access the duodenum • Easy to keep the scope in the second part of the duodenum • Wide angulation range • Up 130°, Down/Left/Right 90° COLOUR & POWER DOPPLER • Colour/Power Doppler provides information on blood flow conditions: • Aids orientation via identification of vessels • Helps distinguish between vessels, lymph nodes and ducts Colour Doppler Power Doppler TISSUE HARMONIC ECHO • Technique that detects & processes 2nd harmonic echoes (double the transmit frequency) for improved imaging: • Reduction in noise & artefacts such as sidelobes • Improved spatial & contrast resolution is achieved Fundamental Tissue Harmonic Echo MINIATURE PROBES • Comprehensive range of miniprobes for use with EU-ME1 Universal EUS Processor • Designs for: • • • • • • Superficial imaging of GI tract (UM-2R/UM-3R) Ultra-Slim Diameter (UM-S20/S30) Guide wire introduction for IDUS (UM-G20/UM-DG20) 3D Scanning (UM-DP12/DP-20/DG20) Rectal (RU-75M/RU-12M) Endobronchial Ultrasound (UM-BS20/UM-S17) • Imaging from 12 to 30MHz offering exceptional resolution MINIATURE PROBES • Dual Plane Reconstruction (DPR) • Used to display radial & linear images simultaneously • Generates two dimensions that directly correlate making images easier to understand SAMPLING & INTERVENTIONAL EUS NEW GF-UCT180 / GF-UCT260 • New Curved Linear Array (CLA) scope offering high performance and flexibility during FNA & Interventional EUS procedures • • • • New Broadband transducer Enhanced CCD Modified 3.7mm channel Supports Contrast Harmonic Echo studies SUPERIOR IMAGE QUALITY • New CCD • Improved optical image quality • Supports Narrow Band Imaging (NBI) • New Broadband Transducer • Greater penetration depth • Improved Doppler sensitivity • Supports Tissue Harmonic Echo & Contrast Harmonic Echo MODIFIED CHANNEL & ELEVATOR DESIGN • 3.7mm channel with modified design allows improved passage of 10Fr devices • Newly designed forceps elevator provides greater stability of the FNA needle SUPPORTS CONTRAST HARMONIC ECHO • Compatible with ultrasound contrast agents*, e.g. Sonovue, Sonazoid • Novel tool for demonstration of microvasculature • May aid differentiation of lesions * Function available with ALOKA Alpha 10 and ALOKA Alpha 7 only EASIER HANDLING • Detachable ultrasonic cable (MAJ-1597) • Benefits for transportation, storage and reprocessing • Ultrasonic cable fits BF-UC180F / BF-UC260FW, offering potential cost saving EBUS EBUS-TBNA • Endobronchial Ultrasound-Guided TBNA • Valuable tool for lung cancer staging and biopsy of bronchial masses LUNG CANCER PATIENT PATHWAY CT STAGING OF LUNG CANCER • Staging by CT-image based on lymph node size alone is not reliable • CT over-stages in up to 25% of cases • CT under-stages in up to 25% of cases • Difficulties exist in detecting nodes < 5mm PET STAGING OF LUNG CANCER • Good negative predictive values (93%) but low positive predictive value (requires tissue) MEDIASTINOSCOPY • Invasive • Expensive • Limited number of stations can be sampled Endobronchial ultrasound guided transbronchial needle aspiration MEDIASTINOSCOPY EBUS-TBNA COMBINED EBUS-TBNA AND EUS-FNA EUS EBUS EBUS-TBNA CLINICAL DATA Sensitivity Specificity Accuracy Herth et al, Thorax 2006 94 100 Yasufuku et al., Chest 2004 95 100 97 Rintoul et al., ERJ 2005 85 100 89 Yasufuku et al, Lung Cancer 2005 94 100 96 MINIMALLY INVASIVE LN STAGING • EBUS-TBNA + EUS-FNA = avoidance of mediastinoscopy • Multiple benefits: • Cost saving (theatre time, anaesthesia, bed stay) • Reduced risk (no GA) • Better for the patient (outpatient procedure) BF-UC180F/260FW: TRANSDUCER HYBRID SCOPE CONSTRUCTION • Combined fiber and video technologies • Narrow insertion tube diameter despite ultrasound functionality DOPPLER FACILITY • Helps to identify vascular structures in the puncture pathway during EBUS-TBNA procedures • Facilitates safer puncture MINIATURISED CURVED LINEAR ARRAY • Miniature Curved Linear Array (CLA) • 6.2mm x 5.6mm • Facilitates easy passage into Bronchi 2.2MM CHANNEL INNER DIAMETER • Large 2.2mm channel offers superior suction and smoother needle insertion SUITABLE FOR OESOPHAGUS • • Complete mediastinal staging Option for EUS imaging in case of oesophageal strictures DETACHABLE ULTRASONIC CABLE • • • Easier reprocessing, handling & storage Cross compatibility with GF-UCT180/260 Connects to a range of Olympus and ALOKA processors RADIAL EBUS • Allows assessment of: • Depth of tumour invasion in central airways for ‘T’ staging • Diagnostic sampling of peripheral lung lesions GUIDESHEATH KIT WITH MINIPROBE GUIDESHEATH KIT WITH MINIPROBE ULTRASOUND PROCESSORS FOR EUS & EBUS PROCESSORS FOR EUS & EBUS • Range of options from Olympus and ALOKA to suit all requirements PRODUCT POSITIONING Compatibility EU-ME1 ALOKA ALPHA 7 EU-M60/ EU-M2000 EU-C60/ EU-C2000 Image Quality ALOKA ALPHA 10 EU-ME1 UNIVERSAL PROCESSOR • Advantages: • Compact design enables simple integration with LUCERA or EXERA II • Maximum versatility - virtually all Olympus ultrasound endoscopes connect • Miniprobe compatibility for specialist applications • Picture-in-Picture function • Dedicated to EUS – easy to learn • Excellent price : performance ratio • 3D scanning EU-ME1 UNIVERSAL EUS PROCESSOR ALOKA PLATFORMS • Compatibility with ALOKA Alpha 10 & Alpha 7 • Advantages: • Premium image quality • Contrast Harmonic Echo capability • Extracorporeal probes NEEDLES FOR EUS-FNA & EBUS-TBNA EZ SHOT2 NEEDLES FOR EUS-FNA • Excellent puncture capability with a choice of needle sizes: • • • • 19 Gauge 22 Gauge 22 Gauge with Sideport 25 Gauge • Uniquely dimpled tip ensures it is clearly visible in ultrasound images VIZISHOT FOR EBUS-TBNA • Dedicated ‘ViziShot’ aspiration needle • Excellent puncture capability with a choice of needle sizes: • • 22G NA-201SX-4022 21G NA-201SX-4021 SUMMARY SUMMARY • Ongoing commitment to providing the widest choice of instruments and highest performance in EUS • Focus on expanding the capabilities of Interventional EUS with the introduction of the GF-UCT180/260 and future products • Continuation of collaboration with Aloka to provide access to advanced ultrasound technologies such as EUS-CHE OLYMPUS EUS