Epicardial Ablation: Another route to be arrhythmia free John R Onufer MD FHRS Epicardial Ablation Scar related Ventricular tachycardia Accessory pathways Atrial fibrillation Idiopathic Ventricular tachycardia Outflow tract Non ischemic cm Sarcoid Chagas ARVD Afib Hybrid lesion set ECG of a PVC originating in the epicardium. Baman T S et al. Circ Arrhythm Electrophysiol 2010;3:274279 Copyright © American Heart Association Left, Venogram of the great cardiac vein (GCV). Baman T S et al. Circ Arrhythm Electrophysiol 2010;3:274279 Copyright © American Heart Association Table 2 Steps taken preprocedurally and intraprocedurally during a case of epicardial access Preprocedural Decide on the likelihood/need for epicardial access 1. Obtain a history of prior cardiac surgery, pericarditis, or pericardial instrumentation 2. Ensure normal coagulation parameters 3. Have surface or preferably intracardiac echocardiography available 4. Obtain a typed blood sample 5. Ensure access to a cardiac surgical team on short notice 6. Intraprocedural Obtain baseline imaging of the pericardial space before obtaining epicardial access 7. Routine double wiring of the pericardial space 8. Use of soft tipped sheaths/do not leave sheath tip exposed 9. Periodic survey of pericardial space by ICE 10 Periodic drainage of the intrapericardial sheath, with or without use of pig-tail catheter ICE Intracardiac echocardiography catheter. Epicardial Access 18g 15cm Epidural spinal needle .032 wire Contrast injection Minimize contrast or will obscure view Echocardiographic monitoring Soft tip sheaths Double wiring the access site Keep sheath occupied with pig tail catheter wire or ablation catheter as sheath can lacerate epicardial vessels or RV Epicardial access Left of xiphoid process Aim to mid clavicular line Push down on the skin to create angle of entrance. Keep open end of needle away from heart on entrance to pericardium Epicardial Access Lungs: the more posterior you advance the less likely to hit lungs Diaphram/infradiaphragmatic vessels Liver: more lateral less risk of injury LIMA: begin 20-30 degrees then angle deeper after past xiphoid towards cardiac silhouette 40 degrees lao Epicardial access Air in pericardium: evacuate as cannot cardiovert nor defibrilate. Aspirate frequently Ablate: initally 15W irrigation 30 cc temp 4041 20-25W average) Sagittal section of a cadaveric specimen. Koruth J S et al. Circ Arrhythm Electrophysiol 2011;4:882888 Copyright © American Heart Association Scar Map of VT Epicardial Fat vs Scar Inferolateral less fat RV free wall and RVOT more fat. >3 mm fat cannot burn through 0-5 mm fat voltage can be similar to normal myocardium. >5 mm will have low voltages and no capture at 10ma unipolar pacing. Endo scar <1.5 mv/ Epi Scar <1 mv with wide split potentials and late potentials Epicardial Access Complications Hemopericardium/tamponade Hemoperitoneum Injury to epicardial vessel (artery or vein) Phrenic nerve injury Hepatic injury Early hemopericardium 1. Inadvertent right ventricular (RV) puncture 2. Perforation of an epicardial vessel (artery/vein) 3. Disruption of pre-existent pericardial adhesions Intraoperative image of the surgically repaired laceration (arrow) to a large-caliber posterolateral branch of the coronary sinus. Koruth J S et al. Circ Arrhythm Electrophysiol 2011;4:882888 Copyright © American Heart Association A, Location of 2 puncture sites (black arrows) within the left hepatic lobe in an image obtained during laparotomy. Koruth J S et al. Circ Arrhythm Electrophysiol 2011;4:882888 Copyright © American Heart Association A, Left anterior oblique view of right coronary angiography. Koruth J S et al. Circ Arrhythm Electrophysiol 2011;4:882888 Copyright © American Heart Association Transverse view of an abdominal CT scan with contrast showing a large heterogeneous lesion in the left hepatic lobe (arrows), measuring 6×7×11 cm. Koruth J S et al. Circ Arrhythm Electrophysiol 2011;4:882888 Copyright © American Heart Association CT angiography of the anterior aspect of the heart illustrating the course of the great cardiac vein in relation to the left anterior descending coronary artery (LAD) and the left circumflex coronary artery (Cx). Baman T S et al. Circ Arrhythm Electrophysiol 2010;3:274279 Copyright © American Heart Association Post ablation Leave Pigtail in place: delayed tamponade Pericarditis: triamcinalone 2mg/kg into pericardium Pain management Summary Epicardial ablation is feasible for arrthythmias There are specific techniques and attention to procedural details that are necessary to avoid complications and optimize outcomes Complications can be avoided and mitigated by a knowledge of the anatomy and the experience of others. Thank you Right ventricular (RV) angiogram reveals contrast entering a crypt (arrow pointing to structure encircled) extending inferiorly below the RV wall. Koruth J S et al. Circ Arrhythm Electrophysiol 2011;4:882888 Copyright © American Heart Association Epicardial VT Morphology