Drugs and Consciousness Psychoactive Drug a chemical substance that alters perceptions and mood Physical Dependence physiological need for a drug marked by unpleasant withdrawal symptoms Psychological Dependence a psychological need to use a drug for example, to relieve negative emotions Dependence and Addiction Big effect Drug effect Tolerance diminishing effect with regular use Response to first exposure After repeated exposure, more drug is needed to produce same effect Little effect Small Large Drug dose Withdrawal discomfort and distress that follow discontinued use Psychoactive Drugs Depressants – “downers” drugs that reduce neural activity alcohol, barbiturates, opiates slow body functions sympathetic NS Psychoactive Drugs Alcohol affects motor skills, judgment, and memory reduces self awareness Disrupts processing of recent events into long-term memories large amts – depressant, small amts - stimulant Animation - Alcohol http://outreach.mcb.harvard.edu/animations/s ynapse.swf http://learn.genetics.utah.edu/content/a ddiction/drugs/mouse.html Psychoactive Drugs Barbiturates tranquilizers, mimic effects of alcohol drugs that depress the activity of the central nervous system, reducing anxiety but impairing memory and judgment Psychoactive Drugs Opiates opium and its derivatives (morphine and heroin) opiates depress neural activity, temporarily lessening pain and anxiety highly addictive Animation - Heroin http://outreach.mcb.harvard.edu/animations/s ynapse.swf http://learn.genetics.utah.edu/content/a ddiction/drugs/mouse.html Psychoactive Drugs Stimulants – “uppers” drugs that excite neural activity caffeine, nicotine, amphetamines, cocaine speed up body functions – nicknamed “speed” Animation Caffeine, Nicotine, Cocaine http://outreach.mcb.harvard.edu/animat ions/synapse.swf http://learn.genetics.utah.edu/content/a ddiction/drugs/mouse.html Psychoactive Drugs Amphetamines drugs that stimulate neural activity, causing speed-up in body functions and associated energy and mood changes more powerful than cocaine Psychoactive Drugs Cocaine effects depend on dosage, form, expectations, personality and situation (coca leaves, powder, crack ) Blocks dopamine, serotonin, norepinephrine – depression, irritability Cocaine Euphoria and Crash Psychoactive Drugs Ecstasy MDMA (methylenedioxymethamphetami ne) stimulant and mild hallucinogen dangerous short and long term effects Blocks the reabsorbtion of serotonin, releases dopamine Animation - Ecstasy http://learn.genetics.utah.edu/content/a ddiction/drugs/mouse.html Psychoactive Drugs Hallucinogens psychedelic (mind-manifesting) drugs that distort perceptions and evoke sensory images in the absence of sensory input LSD MDMA (Ecstasy) Psychoactive Drugs LSD lysergic acid diethylamide, also as acid a powerful hallucinogenic drug chemically similar to serotonin and block it THC the major active ingredient in marijuana triggers a variety of effects, including mild hallucinations cognitive effects out last the use of the drug Animation - LSD http://learn.genetics.utah.edu/content/a ddiction/drugs/mouse.html Near-Death Experiences Near-Death Experience an altered state of consciousness reported after a close brush with death often similar to druginduced hallucinations Psychoactive Drugs Trends in Drug Use Perceived Marijuana Risk Near-Death Experiences Dualism the presumption that mind and body are two distinct entities that interact Monism the presumption that mind and body are different aspects of the same thing Links Meth Ingredients – http://www.kci.org/meth_info/sites/Riverside_County.htm Meth Epidemic – PBS Frontline Series http://www.pbs.org/wgbh/pages/frontline/meth/body/#2