RADS-2 Reynolds Adolescent Depression Scale – nd 2 Edition William M. Reynolds, PhD 1 Introduction The Problem of Depression in Adolescents 2 Depression in Adolescents Depression is one of the most prevalent mental health problems in adults and adolescents, and is a significant problem in children. 3 Depression in Adolescents Depression is an internalizing disorder in that most of the symptoms of depression are covert, subjective in intensity, and internal to the individual. 4 Depression in Adolescents Depression in adolescents is often comorbid with other internalizing as well as externalizing disorders, and may be overlooked due to diagnostic overshadowing . 5 Depression in Adolescents Depression is an insidious and complex mental health problem with multiple etiologies, courses, types, and potential treatments. 6 A Biopsychosocial Model of Depression PSYCHOLOGICAL INFLUENCES Cognitive Appraisal Behavioral and Coping Response Self-Esteem / Interpersonal Skills Social Adaptation Functional and Dysfunctional Cognitions SOCIAL INFULENCES Major Life Events Familial Attachment, Nurturance, & Support Daily Hassles Interpersonal Relationships Social Systems - Life Stressors BIOLOGICAL INFLUENCES Genetic Loading Nervous System Activation Neuroendocrine Functioning Biological Vulnerability Organic/Nutritional 7 Depression in Adolescents National Comorbidity Study (NIMH) 12 Month Depression Prevalence Rates Major Depression Minor Depression 15-16 yr olds 13.0% 6.5% 17-18 yr olds 12.2% 11.2% 8 DSM IV MOOD DISORDERS Major Depressive Disorder Single Episode Recurrent Dysthymic Disorder (early onset) Bipolar Disorder 9 Assessment of Depression in Adolescents For the evaluation of depression, we can diagnose depression according to a classification system such as DSM-IV, or we can assess the severity of the symptoms of depression and obtain a score, with the higher the score the more clinically severe the depression. 10 Assessment of Depression in Adolescents The primary methods used to assess the severity of depression are self-report measures and clinical interviews. Teacher, peer and parent reports are not viable methods. 11 Reynolds Adolescent Depression nd Scale – 2 Edition RADS-2 Requires a third-grade reading level. Allows for scores on four subscales. Development included large samples of school-based (9,000+) and clinical (250+) adolescents. Norms based on a national standardization sample of 3,300 adolescents. Norms extended to ages 11 to 20 years. 25 years of school, clinical, and research applications. 12 RADS-2 Depression Factors Dysphoric Mood Anhedonia/ Negative Affect RADS-2 Total Scale Negative SelfEvaluation Somatic Complaints 13 RADS-2 Subscales Dysphoric Mood (DM) The 8 item DM subscale evaluates symptoms of dysphoric mood and related symptoms, including: sadness, crying behavior, loneliness, irritability, worry, and self-pity. Dysphoric mood represents a prototypic dimension of depression as a disturbance of mood (DSM-IV) and may be viewed as a negative emotional state. 14 RADS-2 Subscales Anhedonia/Negative Affect (AN) The 7 item AN subscale evaluates depressive symptoms associated with anhedonia with several items of negative affect. High scores on this subscale represent limited or lack of interest in pleasurable activities. AN items include symptoms of disinterest in having fun, engaging in pleasant activities, and disinterest in talking with others and eating meals. 15 RADS-2 Subscales Negative Self-Evaluation (NS) The 8 NS items evaluate negative feelings about oneself. Items deal with low self-worth, selfdenigration, feelings of self-harm, that parents and others do not like or care about them, and thoughts of running away, and feeling there is nothing they can do that will help the situation. In some adolescents, this negative self-evaluation is internalized as reflected in thoughts of selfharm, feelings of pervasive helplessness and suicidal thoughts or behaviors. 16 RADS-2 Subscales Somatic Complaints (SC) The 7 SC items evaluate somatic and vegetative complaints (classic symptoms), along with general feelings of malaise (boredom, life is unfair) and irritability. Symptoms include stomachaches, feeling ill, fatigue, and sleep disturbance. 17 Characteristics of the RADS-2 Normative Sample Size of sample 3,300 Gender (n) Males 1,650 Females 1,650 Age Groups 11 – 13 14 – 16 17 – 20 Ethnicity (%) Caucasian African Amer Hispanic Asian Native Amer (n) 1,100 1,100 1,100 70.5 12.1 11.8 4.3 1.3 18 Reliability of RADS-2 Scales RADS-2 scale Internal Consistency Test-retest Clinical Standardization Clinical Dysphoric Mood Anhedonia/Negative Affect Negative Self-Evaluation Somatic Complaints .86 .85 .87 .81 .85 .89 .86 .79 .87 .81 .85 .81 RADS-2 Depression Total .94 .92 .89 19 RADS Research with Special Populations Baker, 1995 Brand, et al., 1996 Brown, et al., 1991 Cauce et al., 2000 Cunniff et al., 1995 Dalley et al., 1992 D’Imperio et al., 2000 Ghaziuddin et al., 1999 Graves & Reynolds,1985 Gutierrez, 1999 Hagborg, 1992 Gifted & exceptionally gifted Major Depression & sexual abuse Suicide attempters Homeless adolescents Turner syndrome Learning disabled Disadvantaged urban city Psychiatric inpatients Behavior disorders Parentally bereaved students Seriously emotionally disturbed 20 RADS Research with Special Populations Hein & Dell, 1995 King et al., 1995a King et al., 1995b King et al., 1996 King, et al, 1997 Manikam, et al 1995 Matson & Nieminen,1987 MacLean et al., 1999 Navarrete, 1999 Nieminen & Matson,1989 Ott & Reynolds, 2001 HIV+(+) in medical settings Psychiatric inpatients Psychiatric inpatients Inpatients w/ major depression Psychiatric inpatients Mental retardation Behavior disordered Homeless adolescents Learning disabled Conduct disordered Mental retardation 21 RADS Research with Special Populations Perks & Jameson 1999 Reid, et al., 1995 Reinecke & Schultz,1995 Ryan, et al., 2000 Sadowski & Kelley,1993 Shain, et al, 1990 Shain, et al., 1991 Sinclair et al., 1995 Spirito, et al., 1987 Spirito, et al., 1993 Williams et al, 1998 Wurzbacher, et al 1991 Witness domestic violence /St. Lucia Adolescents with diabetes Psychiatric outpatients Homeless abused and nonabused Suicide attempters Inpatients w/ Major Depression Psychiatric inpatients Sexually abused adolescents Hospitalized suicide attempters Suicide attempters Incarcerated adolescents Prostitution-involved youth 22 RADS-2 Clinical Severity T-Score Range %ile range Below 61 1 – 81 61 to 64 82 – 92 65 to 69 93 – 96 70 & above 97+ Clinical Description Normal Range Mild clinical depression range Moderate clinical depression Severe clinical depression 23 RADS-2 Scores for School and Clinical Samples The RADS-2 has a possible range of 30 to 120, although raw scores above 100 are rare. The average RADS-2 Total raw score for the restandardization sample was approximately 60. The average raw score for the clinical sample of 297 adolescent psychiatric inpatients and outpatients with formal DSM diagnoses was approximately 75. The average Total raw score for a sample of 107 adolescents with Major Depressive Disorder was 90, equivalent to a standard score of 70T. 24 Clinical Levels of Depression T-Score Raw Score Clinical Description Below 61 61 to 64 65 to 69 70 & above 30-75 76-81 82-88 89+ Normal Range Mild clinical depression range Moderate clinical depression Severe clinical depression Based on the total normative sample N = 3,330 25 Comparisons with Normative Data Primary comparison group for converting raw scores to standard scores is the total standardization sample (N = 3,300). Secondary comparisons may be made with gender, age, and gender within age group standardization groups. 26 Interpretation Dysphoric Mood (DM) High DM scores are suggestive of a distinct disturbance of mood and are often associated with feelings of subjective misery and distress. Some adolescents with high scores may be overly worried or anxious, an aspect of dysphoric mood noted in DSM-IV. 27 Interpretation Anhedonia/Negative Affect (AN) High scores on this subscale suggest a reduced engagement in pleasant activities and a generalized negative affect to self. High scores may reflect low motivation and affect, as well as social withdrawal, a characteristic of anhedonia noted in DSM-IV. 28 Interpretation Negative Self-Evaluation (NS) It is important to recognize that high scores on the NS subscale are indicative of more than negative self-esteem and in some, may reflect extreme negative feelings toward self including thoughts of self-harm (selfmutilation, suicidal ideation, suicidal acts). The scale measures broad symptoms of negative self-evaluation (unrealistic negative self-appraisal, feelings of worthlessness, selfblame), not just negative self-concept. 29 Interpretation Somatic Complaints (SC) Adolescents with elevated scores generally show somatic involvement in their depression, with very high scores suggesting the potential for a depressive episode. It is important to rule out the presence of a prior physical illness that would mimic somatic complaints . 30 Interpretation Critical Items Serve as a double-check if the Depression Total is below the clinical cutoff, yet may be at risk for depression or require additional evaluation. The general rule is if four or more or endorsed, further assessment should be done. They are NOT meaningful indicators of depression in isolation or meant to be used as a screener. 31 Treatment of Depression in Adolescents The research on the treatment of depression in adolescents has focused on pharmacological and psychological interventions. 32 Treatment of Depression in Adolescents Pharmacotherapy Most of the antidepressant drugs developed and tested with adults have also been used, with varying degrees of clinical efficacy, with children and adolescents. In 1993 the FDA approved the first antidepressant for the treatment of major depressive disorders in young people. The American Academy of Child and Adolescent Psychiatry estimates that 5% of the pediatric population -- or 3.4 million children and adolescents under the age of 18 -suffer from depression. This is probably an underestimate. 33 Treatment of Depression in Adolescents Psychotherapy The efficacy of psychotherapeutic interventions for depression in adolescents has been examined in a number of studies. Most of these studies have used treatment procedures developed for adults with modifications made for adolescents. Core empirical studies: Reynolds & Coats, (1986) Kahn, et al., (1990) Lewinsohn, et al., (1990) 34 A Comparison of CognitiveBehavioral Therapy and Relaxation Training for the Treatment of Depression in Adolescents Journal of Consulting and Clinical Psychology (1986) William M. Reynolds & Kevin I. Coats 35 Treatment of Depression in Adolescents Pharmacotherapy The primary classes of antidepressants: Tricyclic antidepressants (TCAs), Monoamine Oxidase Inhibitors (MAOIs), Selective Serotonin Reuptake Inhibitors (SSRIs), and several newer classes of drugs that do not fit these categories. 36 Summary Depression and depressive disorders are prevalent among adolescents. Young people typically do not get better without intervention of some kind. The foremost need is for the identification of adolescents who are at risk and subsequent referral for treatment. There is a need for schools and communities to be proactive in the identification and referral for treatment of at-risk youth. 37