Using Evidence to Make Everyday Decisions ROBIN STEED, PHD, LOTR LOTA CONFERENCE 2014 Objectives and Agenda Part One • Intro: What? Why? • Learn the 5 easy steps: 1. Identify the problem 2. Ask a question 3. Find some answers 4. Evaluate the answers 5. Try the best one out Part Two Practice EBP Skills Easy Checklist Getting Started Part One Introduction to Evidence Based Practice WHAT DID YOU SAY? NOW WHY WOULD I WANT TO DO THAT? What is EBP? knowledge Research Client Factors Clinical Reasoning Best Practice (Sackett ,Straus, Richardson, Rosenberg, & Haynes, 2000). wisdom Why? Client education Why? Client trust Why? Do no harm! NSAIDs do not reduce fibromyalgia pain No evidence to support psychoanalytic (Freudian) treatment Stretching does not prevent or improve contracture Sheltered workshops do not increase employment Cognitive remediation does not improve function Why? Your own peace of mind Why? Our clients deserve the BEST! The Process of Evidence Based Practice Yes, you too can be an evidenced based practitioner in just 5 easy steps! Identify the clinical problem 1 I want my clients to: be more functional have a higher quality of life have better outcomes faster transfer skills to home environment have maintained gains at follow-up have better adherence to treatment plan Types of problems and their questions 1 Assessment/Diagnostic (What is the best assessment to use to identify performance deficits?) Intervention efficacy (What is the best treatment?) Intervention cost-effectiveness (Which treatment gives me the most return for my money?) Identify your problem 1 Complete the problem identification worksheet. Examples: My clients don’t like constraint induced therapy, would a modified approach work just as well? My clients have poor sensory motor skills and have trouble with handwriting. We send instructions home with the clients but we aren’t sure they understand them. A good problem 1 Ask a PICO question 2 Patient or Problem Intervention Comparison Intervention Outcomes PICO Examples 2 In children with autism, evidence on vigorous vs. mild exercise, on stereotyped behaviors? In clients with schizophrenia, evidence on environmental supports on ability to transition to community? In children with hemiplegia, evidence on constraint induced therapy on motor function? Work on step two worksheet Good Questions 2 Within occupational therapy domain “What” questions, not ‘why’ Just right focus, not too wide, not too narrow Measurable in some way Clinically important Not already answered! Take a break and relax! Looking for some answers 3 P: serious or chronic mental illness, psychosis, schizophrenia, mood disorder, anxiety disorder I: child care, meal preparation, home management, shopping, time management, safety, social participation, education exploration, retirement exploration, employment seeking O: employment and education (Arbesman & Logsdon 2011) Types of evidence 3 Meta-analysis Systematic review Critically appraised papers (CAPs) Critically appraised topics (CATs) Individual journal articles wikipedia Where do we find the (free) evidence? 3 AOTA Evidence Exchange Centre for Evidence-based Mental Health Cochrane Consumer Network McMaster Occupational Therapy EBR Reviews National Guideline Clearinghouse™ (NGC) OT Seeker - The Occupational Therapy Evidence Database OT Evidence at www.otevidence.info Everyday Evidence Podcast from AOTA Centre for Reviews and Dissemination Where do we find the articles? 3 Pub Med ncbi.nlm.nih.gov/pubmed Pub Med Central: pubmedcentral.gov Directory of Open Access Journals: www.doaj.org NBCOT if registered (ProQuest) Google Scholar PubMed Central 3 Open Access: • Arthritis • Autism Research • Journal of Pain Research NBCOT 3 ProQuest RefWorks AJOT An easy way to keep OTJR track of your articles OT International OT Canada, NZ Google Scholar 3 Critically evaluate the evidence 4 Read the article Fill out a form Critical Review from McMaster’s University CAP from AOTA CASP in the UK Critically evaluate the evidence 4 Study Design randomization control for bias ethical control group Sample size described Assessment Properties Intervention detailed/replicable Statistical Analysis Threats to Validity internal external Make a decision Given the quality of the evidence, what are the implications for clinical practice? Implement and evaluate 5 Implement Evaluate What is the risk? Choose outcome What is the cost? measures Keep records of outcomes and adverse events Do a ROI assessment Do you need special training? Getting client consent Facility support Take a longer break! Part Two Evidence Based Practice Practice 1. Easy Checklist 2. Getting Started Checklist Are the results valid? Subject selection Research design Data analysis & results Are the results meaningful? Are the results applicable to my client? Source: Portney & Watkins (2009) How were the subjects selected? 1 Random sampling Random assignment Convenience Sample Size? 2 not that great <30> much better Sample Size? 3 Inclusion: who we let in Exclusion: of the ones we let in, who do we kick out How were participants assigned? 4 Did it result in two equal groups at the start? Was the design reasonable? 5 • Exercise 2x week • Constraint Induced Therapy 20 hours/day • A 4 hour workshop on cultural competence Was the intervention the reason for results? 6 • • • • • • • • • History Measurement Instrument Statistical Regression Maturation Unequal Groups Attrition Multiple Treatments Treatment Diffusion Participant Responses History Instrumentation Statistical Regression Maturation Unequal Groups Mortality/Attrition Multiple Treatment Treatment Diffusion Participant’s Reactions Artificial environment in effort to control extraneous variables (can’t generalize to real world) Hawthorne effect- subjects aware of being studied John Henry effect- subjects get competitive between groups Novelty effect- increase motivation because tx is new Was everyone blind to treatment? 7 Did the researchers pick the right assessment? 8 • Toglia Categorization Assessment or the Allen Cognitive Levels to measure change over time. • Using the O’Connor as a measure of functional ability Observation versus self-report Simulation versus natural setting Standardized versus made up test Were the measures valid and reliable? 9 Validity Reliability Content Re-test Face Tester Criterion Internal Consistency Concurrent Pearson’s Alpha r ICC .7 and above Cronbach How many people dropped out of the study? 10 Why? Percentage http://www.englishblog.com/2013/10/cartoon-oreos-more-addictive-than-cocaine.html#.UuqugLTkroI Were the appropriate statistics used? 11 Variables Levels Groups n > 30 n < 30 1 2 1 Paired t test Wilcoxon 2 Unpaired t (independent t) Mann-Whitney U 1 One way repeated measures ANOVA Friedman 2 One way ANOVA Kruskal Wallis 1 2 way repeated measures ANOVA 2+ Two way ANOVA 3+ 2+ Source: Portney & Watkins (2009) Were the results significant? 12 Increased shoulder ROM 10° = function? Power- the ability of a study design to find an effect if there is one, depends on: Effect size- the amount of impact the independent variable has on the dependent variable (Cohen’s d) small= .20 medium= .50 large = .80 Sample size- increases the power to find effect Source: Portney & Watkins (2009) Take another break Are the results meaningful? 13-16 Is the intervention feasible, cost effective? Is there any risk? Is this within the scope of OT? What is the ‘take home’ message? www.haven.com www.bioness.com/Healthcare_Professionals/H200_for_Hand_Paralysis.php Are the results applicable? 17-19 Given the quality of the study, should I apply this to my practice? Do I need extra training? Do I have the resources to replicate intervention? Are subjects similar to my clients? Get Real! LIKE I AM REALLY GOING TO HAVE TIME FOR ALL THIS! Why not? Therapists said . . . Lack of time (87%) Large workload/caseload (67%) Limited searching skills (50%) Limited critical appraisal skills (44%) McCluskey (2003) Expert Solutions Prioritizing daily tasks Making plans & goals Delegating tasks Setting aside blocks of time Dividing into manageable chunks Influences on Success Readiness for change Personal and organizational expectations Presence of deadlines Availability of support EBP in just 10 minutes a day! Join AOTA (Journal Club Toolkit) Listen to AOTA evidence podcast Read one or two journal articles a month Look up the quick summaries on EBP web sites Sign up for evidence alerts at McMaster’s Start an EBP file at work Join/start a journal club Keep records EBP Books on Evidence photos: amazon.com EBP Books on Implementing EBP Reasons to Create Evidence Referrals Client self-efficacy Funding for program Third party payment Resource allocation Keep your job ! References Arbesman, M., & Logsdon, D. (2011). Occupational therapy interventions for employment and education for adults with serious mental illness: A systematic review. American Journal of Occupational Therapy, 65, 238-246. Dunn, (2008). Bringing evidence into everyday practice. Thoroughfare, NJ: Slack McCluskey, A. (2003), Occupational therapists report a low level of knowledge, skill and involvement in evidence-based practice. Australian Occupational Therapy Journal, 50, 3–12. doi: 10.1046/j.1440-1630.2003.00303.x Page, S. J., Levine, P., & Hill, V. (2007). Mental practice as a gateway to modified constraint induced movement therapy: A promising combination to improve function. American Journal of Occupational Therapy, 61(3), 321–327. http://dx.doi.org/10.5014/ajot.61.3.321 Portney, L. & Watkins, M. (2009). Foundations of clinical research (3rd ed.).Upper Saddle River NJ: Pearson. Sackett, D. L., Straus, S. E., Richardson, W. S., Rosenberg, W., & Haynes, R. B. (2000). Evidence based medicine: How to practice and teach EBM (2nd ed.). London: Churchill Livingstone. Gladstone, D. J., Danells, C. J., & Black, S. E. (2002). The Fugl-Meyer Assessment of Motor Recovery after Stroke: A Critical Review of Its Measurement Properties. Neurorehabilitation and Neural Repair, 16(3), 232-240. doi: 10.1177/154596802401105171 Resources at LSUHSC Shreveport www.robinsteed.pbworks.com