The Integumentary System Learning Objectives • List the components of the integumentary system, including their physical relationships. • Specify the functions of the integumentary system. • Describe the main features and functions of the epidermis and dermis. • Discuss individual and racial differences in skin. • Discuss the effects of UV light on the epidermis. • Explain the structure and function of the various accessory organs of the skin. • Explain how the skin responds to injury and aging. The integumentary system consists of • Cutaneous membrane • Epidermis • Dermis • Accessory structures • Subcutaneous layer Integumentary system functions: • Protection • Excretion • Temperature maintenance • Nutrient storage • Vitamin D3 synthesis • Sensory detection Figure 5.1 The Components of the Integumentary System Figure 5.1 SECTION 5-2 The Epidermis Figure 5.2 Thin Skin and Thick Skin • The epidermis is composed of layers of keratinocytes • Thin skin = four layers (strata) • Thick skin = five layers Figure 5.2 The epidermis • Provides mechanical protection • Prevents fluid loss • Keeps microorganisms from invading the body Layers of the epidermis: • Stratum germinativum • Stratum spinosum • Stratum granulosum • Stratum lucidum • Stratum corneum Figure 5.3 The Epidermal Ridges of Thick Skin Figure 5.3 Epidermal characteristics: • Cells accumulate keratin and eventually are shed • Epidermal ridges are interlocked with dermal papillae • Fingerprints • Improve gripping ability • Langerhans cells (immunity) in s. spinosum • Merkel cells (sensitivity) in s. germinativum Figure 5.4 The Structure of the Epidermis Figure 5.4 Skin color depends on • Blood supply • Carotene and melanin • Melanocytes produce melanin and protect from UV radiation • Epidermal pigmentation • Interrupted blood supply leads to cyanosis Figure 5.5 Melanocytes Figure 5.5a, b Epidermal cells • Synthesize vitamin D3 (cholecalciferol) when exposed to UV • Respond to epidermal growth factor • Growth • Division • Repair • Secretion SECTION 5-3 The Dermis Dermal Organization • Papillary layer • Contains blood vessels, lymphatics, sensory nerves of epidermis • Reticular layer • Contains network of collagen and elastic fibers to resist tension Figure 5.8 Dermal Circulation Figure 5.8 Stretch marks • Caused by excessive stretching of the dermis • Patterns of collagen and elastic fibers form lines of cleavage Figure 5.7 Lines of Cleavage of the Skin Figure 5.7 Dermal Circulation and innervation • Cutaneous plexus arteries found in subcutaneous layer/ papillary dermis • Cutaneous sensory receptors (light touch, pressure) Hypodermis • Stabilizes skins position against underlying organs and tissues SECTION 5-5 Accessory Structures Hairs • Originate in hair follicle • Composed of root and shaft • Root base (hair papilla) surrounded by hair bulb and root hair plexus • Hairs have soft medulla and hard cortex • Cuticle = superficial dead protective layer Figure 5.9 the Anatomy of a Single Hair Figure 5.9 Hair types • Vellus hairs (peach fuzz) • Terminal hairs ( heavy) • Club hair (cessation of growth) • Shed and grow according to hair growth cycle Arrector pili muscle attaches to hair Figure 5.10 Hair Follicles Figure 5.10a-c Glands in the skin • Sebaceous • Suderiferous • Mammary • Ceruminous Sebaceous glands • Discharge waxy sebum onto hair shaft when associated with hairs • Sebaceous follicles discharge onto epidermal surface Figure 5.11 Sebaceous Glands and Follicles Figure 5.11 Suderiferous glands • Apocrine sweat glands • Produce odorous secretion • Merocrine (eccrine) sweat gland • Sensible perspiration Figure 5.12 Sweat Glands Figure 5.12a, b Other glands • Mammary glands • Structurally similar to apocrine sweat glands • Ceruminous glands • In ear, produce waxy cerumen Nails • Nail body covers the nail bed • Nail production occurs at the nail root • Eponychium (cuticle) overlies root • Free edge of nail extends over hyponychium Figure 5.13 The Structure of a Nail Figure 5.13 SECTION 5-7 Local Control of Integumentary Function Injury and repair • Regenerates easily • Regeneration process includes formation of • Scab • Granulation tissue • Scar tissue Figure 5.14 Integumentary Repair Figure 5.14, step 1-2 Figure 5.14 Integumentary Repair Figure 5.14, step 3-4 SECTION 5-4 The Subcutaneous Layer You should now be familiar with: • The components of the integumentary system, including their physical relationships. • The functions of the integumentary system. • The main features and functions of the epidermis and dermis. • Individual and racial differences in skin. • The effects of UV light on the epidermis. • The structure and function of the various accessory organs of the skin. • How the skin responds to aging. SECTION 5-7 Aging and the Integumentary System With age • Integument thins • Blood flow decreases • Cellular activity decreases • Repairs occur more slowly