mesopeels MENU Range of chemical peelings for skin renovation and rejuvenation MENU mesopeel Index Introduction Mesopeel hidroxiacids Mesopeel combined Mesopeel trichloroacetic Application protocol MENU mesopeel introduction line of chemical peelings for the treatment and correction of different cutaneous disorders. Based on the used dermopeeling, we can achieve: Different degrees of exfoliation, and therefore superficial depigmentation and scarring attenuation. Stimulation and reorganization of the collagen and elastin fibres, improving physiological and mechanical qualities of the skin. Increased fibroblast activity , that synthetises different macromoléculas on the extracelular matrix and more hydration. Correct sebaceous secretion and a decrease on the number of imperfections. MENU mesopeel introduction Epidermis pH 4.2 – 5.6 (sweat and sebum) + Acid in men + Acid in dry skins Elastin Dermis pH 6 – 7 (vessels and fibres) Glycosaminoglycan Collagen MENU Complete renovation in 28 days mesopeel Mechanism of action A chemical peeling acts on the skin though three mechanisms: TISSUE DESTRUCTION INFLAMMATION MEDIATORS ACTIVATION FORMATION OF NEW COLAGEN MENU mesopeel Mesopeel hydroxide acids mesopeel hydroxide acids lactic_ melanostop_ peel AL peel mandelic_ mesopeel_ peel AM azelan salicylic_ mesopeel_ peel AS jessner glycolic_ peel AG MENU mesopeel combinados mesopeel Classification mesopeel hydroxide acids MENU mesopeel combinados mesopeel tricloroacético lactic_ melanostop_ mesopeel_ peel AL peel TCA soft mandelic_ mesopeel_ peel AM azelan mesopeel_ TCA salicylic_ mesopeel_ peel AS jessner glycolic_ piruvex_ peel AG peel mesopeel Mesopeel hydroxide acids mesopeel hydroxide acids: • They are organic acids that contain an hydroxide group. • Various concentrations (weight and volume). AHA´s • Glycolic Acid • Mandelic Acid • Lactic Acid MENU BHA´s • Salicylic Acid mesopeel mesopeel hydroxide acids Hydroxide acids glycolic_peel AG lactic_peel AL mandelic_peel AM salicylic_peel AS MENU mesopeel mesopeel hydroxide acids Hydroxide acids are organic acids that contain an hydroxide group. Alpha-hydroxide acids (AHA’s) have the hydroxide group next to carboxyl, from which it derives: • Glycolic Acid • Mandelic Acid • Lactic Acid Beta-hydroxide acids (BHA’s) have it further in the molecule, from which it derives: • Salicylic Acid General characteristics of the mesopeels hydroxide acids are the following: • • • • MENU Various concentrations (weight and volume) pH 1,8 Cosmetic form : fluid transparent gel without preservatives Presentation: 50ml container + measuring glass + neutralizer mesopeel mesopeel hydroxide acids glycolic_peel AG General characteristics: Formulated for intensive skin care for Photo-aging, cutaneous stains, imperfections in skins with tendency to acne or other causes. Stimulate the cellular regeneration and the synthesis of collagen. Mechanism of action: • Destroys the protein bindings between the corneocytes. • Stimulates the production of collagen in the fibroblasts. Indication: • Ideal for all types of skins. • Reduction of wrinkles depth. • Diminishes post acne scarring. MENU Concentractions: 20%, 35%, 50%* and 70%*. (*)Concentrations of 50% and 70% are of exclusive medical use mesopeel mesopeel hydroxide acid lactic_peel AL General characteristics: Indicated for mild or moderated photo-aged skins Soften contours, improves the texture, tone and aspect of the skin in general. Mechanism of action: • Destroys the protein bindings between the corneocytes causing the to detach. • Stimulates the production of GAG’s in the dermis and increases its hydration. • It is less aggressive than Glycolic Acid for the skin. Indication: • Ideal for dry and sensitive skins. • Stretch marks. • Actinic damage. MENU Concentrations: 30%, 40%* and 50%*. (*) the concentration of 50% is for exclusive medical use. mesopeel mesopeel hydroxide acids mandelic_peel AM General characteristics: Indicated for fight imperfections of skins with tendency to acne that can also combine Photo-ageing and/or hyperpigmentation. Produce a mild and progressive exfoliation . Antiseptic and depigmentation effects. Mechanism of action: • Breaks the unions between corneocytes of the stratum corneum, as well as the cellules of the epidermis and the dermis. • Stimulate the synthesis of collagen and proteoglycans. • Induce a process of cutaneous rejuvenation. Indication: • Ideal for thick, oily and seborreic skins. • treatment of hyperchromies. • Photo-aging / Dilated pores. MENU concentrations: 30%, 40% and 50%*. (*)concentration of 50% is of eclusive medical use mesopeel mesopeel hydroxide acids salicylic_peel AL General characteristics: Formulated to reduce or eliminate imperfections in skins with tendency to acne, photoaging alterations and wrinkles. Controls the proliferation of “propionilbacterium acnes”. Mechanism of action: • Liposoluble substance that eliminates intercellular lipids. • It does not have inflammatory action, and therefore it is safe in skins predisposed to PIH (Post-inflammatory Hyperpigmentation). Indication: • Hyperkeratosis skins . • Oily / proacneic skins. • Acneic skins. • Ideal as deep hygiene treatment . MENU Concentrations: 10%, 20% and 30%*. (*) The concentration of 30% is of exclusive medical use mesopeel mesopeel hydroxide acids MAXIUM RECOMMENDED EXPOSITION TIMES Lactic peel AL (Lactic Acid) Concentration 30% 40% 50% time 10’ 7’ 7’ mandelic_peel AM (Mandelic Acid) Concentration 30% 40% 50% time 10’ 7’ 5’ salicylic_peel AS (Salicylic Acid ) Concentration 10% 20% 30% time 10’ 7’ 5’ glycolic_peel AG (Glycolic Acid) Concentration 20% 35% 50% 70% time 10’ 10’ 6’ 3’ * The maximum exposition time will always be subject to the professional criteria. MENU mesopeel Combined mesopeel mesopeel hidroxiácidos lactic_ melanostop_ peel AL peel mandelic_ mesopeel_ peel AM azelan salicylic_ mesopeel_ peel AS jessner glycolic_ peel AG MENU mesopeel combined mesopeel Combined mesopeel mesopeel hidroxiácidos MENU mesopeel combined mesopeel tricloroacético lactic_ melanostop_ mesopeel_ peel AL peel TCA soft mandelic_ mesopeel_ peel AM azelan mesopeel_ TCA salicylic_ mesopeel_ peel AS jessner glycolic_ piruvex_ peel AG peel Combined melanostop_peel mesopeel_azelan mesopeel_jessner modified MENU Combined melanostop_peel mesopeel_azelan mesopeel_jessner modified piruvex_peel MENU mesopeel Combined mesopeel melanostop_peel General characteristics: Its effect is based on the synergic action of the three active ingredients that work jointly. Composition: • Azelaic Acid 20%: Essentially metabolic activity. Antioxidant properties. • Resorcinol 10%: Whitening effect. • Fitic Acid 6%: depigmentation. Mechanism of action: • Inhibition of formation of abnormal melanic pigmentations. • Renovation of the epidermis. • Whitening effect Indications: • Treatment of superficial melasma. • epidermal solar lentigo. • Body hypercromies (armpits, knees, groin, etc…) MENU mesopeel Coadjuvant products melanogel antispot cream melanogel touch // Depigmentation cream puntual depigmentation treatment post-treatment Apply morning and night Depigmentation cream for all types of skins. MENU post-treatment Apply morning and night puntual depigmentation treatment . mesopeel Combined mesopeels mesopeel_azelan General characteristics : Especially indicated in oily skins or with acneic tendency. Treatment of acne in all its different manifestations. composition: • Azelaic Acid 20%: Activity essentially metabolic. Antioxidant properties. • Salicylic Acid 20%: Epidermical exfoliation. Antiseborrheic action. Indications: • Oily proacneic skins. • Mild or moderate acne. • Comedonal skins. MENU mesopeel Productos coadjuvants purifying cleanser // purifying face mask // Facial gel mask facial exfoliant continous maintenance continous maintenance application morning and night application morning and night Descaling and purifying facial mask. Cleansing facial gel for oily and proacneic skins. purifying cream // Maintenance cream post-treatment post-treatment application morning and night Puntual application Eases the superficial peeling and prevents pore obstruction. MENU cosmelan active system spot treatment Sebum regulation puntual treatment mesopeel Combined mesopeel mesopeel_jessner modified General characteristics: Ideal for faded skins care , with signs of chronologic aging , superficial scars and epidermal hyperpigmentations. Composition: • Salicylic Acid 14%: Keratolytical exfoliating and comedolytic effect. • Lactic Acid 14%: Gives tautness and hydration to the skin. Activates the formation of collagen and elastin. • Citric Acid 8%: Lesser keratolytical action due to its heavier molecular weight. Similar properties to Lactic Acid. Indications: • Photoaging. • Antiaging treatments. • Post-acne scarring. MENU mesopeel Coadjuvant products post-treatment post-treatment continous maintenance continous maintenance Cosmeceutical line with high concentrations of Vitamin C. MENU Cosmeceutical line with high concentrations of marine collagen. mesopeel Combined mesopeel piruvex_peel General characteristics: Specially indicated to tackle photo-aging, thin and deep wrinkles. Useful in acne and thin seborrheic keratosis. Increases the tone, luminosity and softness. Composition: • Pyruvic Acid 40%: Tackles chrono- and photo-aging. • Lactic Acid 10%: Stimulates new collagen, elastic fibres and glycoproteins production. Indication: • Chronologic aging. • Photo-ageing. • Deep wrinkles. • Post-acne scarring. • Seborrheic and actinic keratosis. MENU mesopeel Productos coadjuvants post-treatment post-treatment continous maintenance Cosmeceutical line with high concentrations of vegetal stem cells. continous maintenance global antiage treatment that includes [meso]recovery complex. MENU mesopeel Exposition time MAXIMUM RECOMMENDED EXPOSITION TIME FACE NECK BODY melanostop_peel 5 minutes 2 minutes 5 minutes mesopeel_azelan 10 minutes 2 minutes 5 minutes mesopeel_jessner 10 minutes 2 minutes 10 minutes piruvex_peel 3 minutes 2 minutes 3 minutes * The maximum time of exposition will be subject to professional opinion. MENU mesopeel mesopeel trichloroacetic mesopeel hidroxiácidos MENU mesopeel combinados mesopeel trichloroacetic lactic_ melanostop_ mesopeel_ peel AL peel TCA soft mandelic_ mesopeel_ peel AM azelan mesopeel_ TCA salicylic_ mesopeel_ peel AS jessner glycolic_ piruvex_ peel AG peel Trichloroacetics mesopeel_TCA soft mesopeel_TCA MENU mesopeel mesopeel tricloroacético mesopeel_TCA and mesopeel_TCA soft General characteristics: Trichloroacetic Acid is derived from Acetic Acid through by chloration of three hydrogenate ions. Treats superficial and mid lesions. • Superficial lesions: superficial hyperchromies, comedonal acne , thin wrinkles . • Mid lesions: Acne damage reversion, actinic keratosis, wrinkles, dyschromy. Mechanism of actuación: • Acts by floculation pf skin proteins. • Produce the precipitation of proteins by hydrofobic interaction. hidrofóbica. Indication: • Treatment of photo-aging, wrinkles, actinic and seborrheic keratosis, pigmentary dischromies, acne and acne scars; and lack of facial luminosity. MENU mesopeel Treatment protocol PHASE PRIOR TO TREATMENT: Complete a clinical record (anamnesis) All the relevant data will be collected such as , habits, personal or technical (skin type, lesion types, associated problems) and any factors related to the disorder. Personalized diagnosis In order to adapt the application protocol based on the needs of each patient Fill out the informed consent form Involving the patient on the treatment process, and also at the same time invite them to continue with the home treatment (fundamental protocol) Photographic register Guaranteing an objetive assessment of the evolution of results Control visits It is important to carry out control visits with an adapted periodicity based on the particular needs of each case. MENU mesopeel Treatment protocol CONSIDERATIONS WHEN WE CARRY OUT A CHEMICAL PEELING • Treatment with retinoid (6 month wash out period). • Active herpes lesions. • Pregnancy. • History of keloids or hypertrophic scars. • Solar allergies or photo-sensitization. • Hypersensitivity reaction to peeling. • Radiotherapy treatment. • Previous surgery in the area where the peeling it will applied. MENU mesopeel Treatment protocol Mesopeel application protocol Phase 1: preparation Remove make up and tone up with hydra milk cleanser and hydratonic. Phase 2: degrease Apply professional degreasing lotion with a gauze and rubbing. MENU mesopeel Treatment protocol Mesopeel application protocol Phase 3: protect Protect with mesolips protector areas that due to their sensitivity must not be in contact with the peeling. Phase 4: treat Apply with a brush or gauze the selected peeling according the type of skin and estetopathy that will be treated. Control the exposition time. MENU mesopeel Treatment protocol Mesopeel application protocol Phase 5: remove and neutralise Remove with abundant water and spray the area treated with post-peel neutralizing spray. Phase 6: enhacing the result Apply the mask post-peel crystal fibre mask or anti-stress face mask and leave in exposition for 20 minutes. MENU mesopeel Treatment protocol Mesopeel application protocol Phase 7: complete and protect After removing the mask apply post-procedure fast skin repair cream. Apply moisturising sun protection. MENU mesopeel Treatment protocol CHANGES IN THE SKIN DURING THE TREATMENT Sensation of tightness MENU This sensation is relieved through the repeated application of products that encourage reepitelization and hydration. PEELING It is an expected evolution after carrying out an Acid based treatment. Frost The frosty areas must be moisturised repeatedly on subsequent days. Burning Typical treatment manifestation; Cool air may relieve this sensation. Erythema According to skin sensitivity, erythema may appear, being a temporary manifestation. mesopeel Treatment protocol APPLICATION OF CHEMICAL PEELINGS| CYCLES OF TREATMENT Peeling as previous treatment Peeling as como specific treatment Peeling as maintenance MENU Before another more specific type of treatment , it is advisable to prepare the skin with the peeling application . For this reason, it is advisable to carry out a session 10 days before applying treatment with mesohyal, treatment antiaging, photogen system, tmt system, amongst others. When an estetopathy is treated with peelings, cycles of 6 to 8 sessions are recommended. It is advisable to carry out a peeling in every season of the year, once every 3 months approximately. mesopeel Results | Clinical cases Before MENU After mesopeel Results | Clinical cases Before MENU After mesopeel Results | Clinical cases Before Firstsession: salicylic_peel 10 % + 3 sessions peeling combined MENU After mesopeel Results | Clinical cases Before After 6 sessions mesopeel glycolic_peel AG 20% and 35% MENU mesopeel Results | Clinical cases MENU mesopeel mesoestetic peelings advantages THEY CAN BE USED IN ANY SEASON OF THE YEAR APPLICABLES TO ANY PHOTOTYPE IDEAL FOR BOTH FACIAL AND BODY TREATMENTS FAST, SIMPLE AND HARMLESS APPLICATION VISIBLE RESULTS FROM THE FIRST APPLICATION THEY NO DOT REQUIRE RECOVERY PERIOD MENU mesopeel Peelings registered at Agencia Española de Medicamentos y Productos Sanitarios mesoestetic glycolic_peel AG 20% / 318-PE mesoestetic glycolic_peel AG 35% / 316-PE mesoestetic glycolic_peel AG 50% / 326-PE mesoestetic glycolic_peel AG 70% / 325-PE mesoestetic lactic_peel AL 30% / 315-PE mesoestetic lactic_peel AL 40% / 322-PE mesoestetic lactic_peel AL 50% / 321-PE MENU mesopeel Peelings registered at Agencia Española de Medicamentos y Productos Sanitarios mesoestetic mandelic_peel AM 30% / 317-PE mesoestetic mandelic_peel AM 40% / 320-PE mesoestetic mandelic_peel AM 50% / 319-PE mesoestetic salicylic_peel AS 10% / 314-PE mesoestetic salicylic_peel AS 20% / 324-PE mesoestetic salicylic_peel AS 30% / 323-PE MENU mesopeel Peelings registered at Agencia Española de Medicamentos y Productos Sanitarios mesoestetic mesopeel_TCA / 364-PE mesoestetic mesopeel_TCA Soft / 365-PE mesoestetic melanostop_peel / 370-PE mesoestetic mesopeel_azelan / 368-PE mesoestetic piruvex_peel / 366-PE MENU mesopeel FAQ’s – mesopeel 1. How does a chemical peeling work? Besides of smoothing the skin, it unleashes series physiological reactions and increases cutaneous permeability, stimulating the synthesis of collagen through a controlled aggression of the skin (decrease of pH). 2. What performance can I get in sessions with a bottle of peelings? Each bottle of peeling contains enough product for approximately 10 facial applications (5 ml. per session). 3. Hoy do I ken te peeling once oponed? It can be perfectly kept at room temperature, closing it properly to avoid that it vaporises and the gel base solidifies. In case that it adopts a very viscose consistence, it can be rinsed with abundant hot water and shake it well until it reaches gain the right texture to apply it. MENU mesopeel FAQ’s 4. How long must we leave between from the solar exposition solar until the application of treatments with chemical peelings? We must always assess the type and condition of the skin and absence of photo-sensitizing factors. As a general rule, it is advisable to leave 10 days from the extended solar exposition until the application in cabin of chemical peelings. 5. Is it advisable to combine peelings with electro-aesthetic techniques? Chemical peeling is a quite complete treatment, however, it can be combined with topical treatments that act as coadjuvants in the same session, and it is important not to combine it with techniques that involve thermic or light stimulation in the same session, because it may cause photosensitivity reactions. MENU mesopeel FAQ’s 6. What products can recommended for home care after a treatment with chemical peelings? According the type of peeling used and the skin conditions, certain specific patterns of treatment will be established. However, there are recommendable products for all cases: MENU • post-procedure fast skin repair: during the 72 hours after the peeling application in cabin (only if there is peeling). • hydra vital factor K: Moisturises. • anti-stress face mask or hydra-vital face mask: once a week at home. • The use of a moisturising sun protection is essential. mesopeel FAQ’s 7. Is it necessary that the skin peels to produce a result? The reactions of the skin are unique and unpredictable, but we can have an expectation of results more or less standard for our treatments, but the way every individual reacts is unique, and therefore, it can be expected that some skins peel, while others do not , and logically, some people have a faster response than others. The peeling, does not involve a better result, and probably in cases where there is no distinctive peeling, the result will take slightly longer to be evident, but internally the same dermal stimulation occurs. In terms of the dryness and tightness sensation, it indicates that the skin is recovering after the application of peeling, and the only thing that can be done to balance it is to moisturise it continuously, and we must also keep in mind that external factors make this sensation more pronounced (cold and heating). MENU mesopeel FAQ’s 8. What special precautions should be taken in consideration when performing treatments with chemical peelings in high phototypes? It should be considered that the darker the skin, it gets more inflamed and, therefore, it has greater risk of post-inflammatory hyperpigmentation unless extreme solar care. In these cases, the best way of proceeding is to avoid aggressive peels and use discrete concentrations, performing a increased number of sessions. Do not perform other exfoliating techniques for 3 weeks prior to treatment. In male skins, shaving is not recommended 24 hours prior to treatment. 9. Is there here is a minimum of preset exposition time? No, once peeling is applied, it is the normal reaction of the skin itself, that determines the exposition time, the times indicated in the tables are the maximum recommended. MENU mesopeel FAQ’s 10. Can a chemical peeling be applied on a skin that it is still peeling? No, in that case, you should wait until the skin fully recovers before a new session. 11. What is the minimum time recommended intersession? 10 days recommended. 12. In body treatments, what are the peelings used for and how are they applied? They are used as phase of preparation of the skin for body treatments in anya rea, and they are applied in the same way in the face and the exposition times will vary according ot the skin conditions (specially folded skin thickness). The most common applications in body are: treatments of pigmentation in arms and hands, necklines, stretch marks in abdomen and buttocks; acne in back, as keratolytic in elbows, knees and feet, and finally as general maintenance of the condition of the skin . MENU mesopeel FAQ’s 13. It is mandatory the use of professional degreasing lotion before of the application of chemical peelings? It is not mandatory but highly recommended to obtain a uniform penetration of the chemical peeling, as it prepares the skin, evaporating the hydrolipidic layer and eliminating impurities of the cornea layer. 14. What peeling is more effective to treat facial acne : salicylic peel_AL or mesopeel_azelan? Is it one stronger than the other? Are they complementary or do they need to be substituted? They are actually complementary options: MENU − salicylic peel_AL indicated to treat keratinized skins in the first sessions of treatment. − mesopeel_azelan specífic for cases of acne in active phase, when there is an infection present or inflamamation, and for treating post-acne scarring. Chemical peelings MENU