UNC-Chapel Hill and the
NIH
Roadmap
NIH ROADMAP
Tony G.Waldrop
Vice Chancellor
Research and Economic Development
NIH’s
Roadmap
Vision
• Est. 2% of total NIH budget
• Primary funding source: “tax” on
NIH institutes
•
•
•
•
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Emphasis:
Attacking difficult problems
Interdisciplinary collaboration
Translation to clinic
Computation/informatics
• Allied projects will make Roadmap
much larger than its core funding
Dr. Elias Zerhouni
Themes
New Pathways to Discovery
• Building Blocks, Pathways, and
Networks
• Molecular Libraries and Imaging
• Structural Biology
• Bioinformatics and Computational
Biology
• Nanomedicine
Research Teams of the Future
• High-Risk Research
• Interdisciplinary Research
• Public Private Partnerships
Re-engineering the Clinical
Research Enterprise
Dorsal root ganglia neurons
(Annette Markus)
• Clinical Research
Roadmap
Planning
at UNC
• September, 2003: Dr. Zerhouni
announces the Roadmap
• January, 2004: 12-member Carolina
Roadmap Task Force is convened
• March, 2004: Task Force report
recommends:
– Create a campus-wide organization for
Roadmap projects
– Demonstrate administrative support
– Appoint a Roadmap chair
– Provide staff and resources
UNC’s
Response
• NIH Roadmap Executive Committee
•
Chair: Rudy Juliano, Professor of Pharmacology
• Executive Committee members:
– Kim Brouwer, Chair Pharmacotherapy, Pharmacy
– Barbara Entwisle, Director, Carolina Population
Center and Professor of Sociology
– Michael Fried, Professor of Medicine and Director,
Hepatology Division of Gastroenterology and
Hepatology
– Daniel Reed, Vice Chancellor for Information
Technology and Director, Institute for Renaissance
Computing
– Rich Superfine, Professor of Physics
– David Savitz, Chair of Epidemiology
Campus
Support
•
Roadmap Committee will steer efforts to
– Build research teams and partnerships at
UNC
– Liaise with NIH on Roadmap
– Highlight interdisciplinary research
(‘workshops’)
– Facilitate development of proposals
– A new staff position (Karen Stone)
Freeze-dried,
rehydrated platelets in
a canine carotid artery.
(Tom Fishcher)
•
Seed funding from VC for proposal development
•
Additional support from
– Offices within Research and Economic
Development
– College of Arts and Sciences
– Schools of Medicine, Dentistry, Public Health
Action
• The first round of Roadmap P20 RFAs
yields multiple UNC proposals
• REC meets with multiple
Departments/Centers
• VC’s “Workshops In Interdisciplinary
Research”
• Emerging Initiatives
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•
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Fluorescent video
microscopy images of
cell mitosis (Ted
Salmon)
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•
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Metabolomics— Steve Zeisel, others
Stem Cells & Transplantation—Jon Serody, others
Peridontal Disease—Steve Offenbacher, others
Biomedical Research Imaging Center—Etta Pisano,
others
Pathways & Networks—Klaus Hahn others
Child abuse & physiological changes- Jonathan Kotch,
others
Other projects??
SUCCESSES
Roadmap Planning Grant or other Awards
PI
Theme
1.
2.
3.
4.
Obesity
Population Center
Land Use & Health Population Center
Imaging Inflammation Medicine
Exploratory Genetics Computer Sci/
Genetics
Nanomedicine
Pharmacology
Patient Outcomes
Public Health
B. Popkin
R. Rindfuss
B. Sartor
D. Reed/
T. Magnuson
5. G. Johnson
6. H. Guess
Department/Center
WHAT NEXT?
1. LOOKING FOR A FEW
GOOD MEN/WOMEN
2. DARE TO DREAM BIG DREAMS
Help the Roadmap at UNC
1. Consider leading a Roadmap or Roadmap-Like proposal.
Let us know about it!!
2. Help us to ‘penetrate’ the NIH. Are you on NIH Council?
Study Section? Advisory Group? Let us know about it!!