What Your CTSA Can Do for You! The University of Chicago Institute for Translational Medicine Julian Solway, MD ITM Director NCRR-funded Consortium of 55 CTSAs The University of Chicago ITM/CTSA NorthShore University HealthSystem Argonne National Laboratory CHeSS Center for Medical Ethics Illinois Institute of Technology CTSA Solway/Ross CTSA Advisory Boards, esp CARC IGSB Comp. Cancer Center CIHDR INSTITUTE FOR TRANSLATIONAL MEDICINE Solway/Ross (Gomez/Pollack) UHI Clinical Trials Cluster Community Translational Science Cluster Schilsky/Cohn/ Stadler Burnet/Miller/Ewigman Population Sciences Cluster Core Support & Technology Cluster Thisted/Ross Weiss Training Cluster Beyer/Meltzer/Olopade COMMITTEE ON CLINICAL AND TRANSLATONAL SCIENCE Meltzer (Beyer/Weichselbaum/McNally/Daum) Advocate ACCESS CHAS What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • • • • • • • Support your multidisciplinary research with external capabilities • • • • • Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities • • • • • Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU) What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • • • • • • • Support your multidisciplinary research with external capabilities • • • • • Research navigation – CTSA Discovery Match http://itm.uchicago.edu/intranet Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities • • • • • Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU) What Your CTSA Can Do for You! What Your CTSA Can Do for You! What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • • • • • • • Support your multidisciplinary research with external capabilities • • • • • Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities • • • • • Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU) What Your CTSA Can Do for You! Funding Mechanism Maximum Award Principal Amt (Approx # Characteristics Awards/Yr) Clinical and Translational Human Subjects Studies $40,000 (11) Community Collaborative Research Studies $50,000 (4) Short-term Studies by Post-doctoral ClinicianScientists $5,000 (5) Collaborative Studies Among NorthShore $75,000 (5) University HealthSystem and UC Researchers Proposed research must involve human subjects - i.e., require IRB approval or IRB exemption Must include investigators from both UC and the Community Restricted to clinicianscientists in training (residents or post-doctoral fellows, or equivalent) Must include investigators from both UC and NorthShore University HealthSystem Application Receipt Dates 10/15/10 01/15/11 04/15/11 07/15/11 10/15/10 01/15/11 04/15/11 07/15/11 Any time 10/15/10 01/15/11 04/15/11 07/15/11 Preclinical Pilot Translational Studies $40,000 (3) Intended for preclinical studies of biology or drug or device development 10/15/10 01/15/11 04/15/11 07/15/11 Core Subsidy Mini-Awards $5,000 (25) Any time Community Projects Mini-Awards $5,000 (6) Must be used to pay charges of a BSD core Must be used to pay costs incurred by a community partner in planning, executing, or reporting a research or demonstration project Any time What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • • • • • • • Support your multidisciplinary research with external capabilities • • • • • Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities • • • • • Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU) What Your CTSA Can Do for You! Clinical Resource Center • • Inpatient studies – intensive nursing, nutritional support, monitoring of all sorts No hospitalization costs or routine supply costs to investigators (except industry supported research) • • Outpatient studies – wide range of capabilities, including invasive procedures Extension into community anticipated • Satellite CRC at NSUHS, less well subsidized • Laboratory services including DNA extraction and storage What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • • • • • • • Support your multidisciplinary research with external capabilities • • • • • Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities • • • • • Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU) What Your CTSA Can Do for You! Biostatistics, study design, ethics, epidemiology advice • • Biotime Clinic – http://biotime.uchicago.edu Free 1 hr consultation, Tues 9–1, walk-in or appt, in Biostats Lab on MARP 3 • • Research Ethics Consultation service – Dr. Lainie Ross Adult and pediatric Research Subject Advocates • Epidemiology advice on individual basis What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • • • • • • • Support your multidisciplinary research with external capabilities • • • • • Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities • • • • • Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU) What Your CTSA Can Do for You! Bioinformatics support and advice • Initiative in Biomedical Informatics (iBi) http://ibi.uchicago.edu • Wide range of genetic/genomic computation tools and expertise • REDCap research data capture system • High performance and grid computing • TraM – integrating translational data mart http://tram.uchicago.edu and related informatics resources … • eVelos – clinical trials management system offered through UCCCC • TRIDOM – translational research initiative in the Dept of Medicine http://tridom.bsd.uchicago.edu • HIRO – human imaging research office in the Imaging Research Institute What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • • • • • • • Support your multidisciplinary research with external capabilities • • • • • Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities • • • • • Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU) What Your CTSA Can Do for You! Community Engagement help • Entrée into community through Community Connections, Center for Community Health and Vitality, interface with Chicago Dept of Public Health, NSUHS connections with Lake County Health Dept • Advice on Community-involved research and research priorities from Community Advisory and Review Council (CARC) • Practice-based research network (South Side, ACCESS, NSUHS) • Emerging relationship with Woodlawn Children’s Promise Community What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • • • • • • • Support your multidisciplinary research with external capabilities • • • • • Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities • • • • • Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU) What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • • • • • • • Support your multidisciplinary research with external capabilities • • • • • Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities • • • • • Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU) What Your CTSA Can Do for You! What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • • • • • • • Support your multidisciplinary research with external capabilities • • • • • Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities • • • • • Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU) What Your CTSA Can Do for You! What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • • • • • • • Support your multidisciplinary research with external capabilities • • • • • Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities • • • • • Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU) What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • • • • • • • Support your multidisciplinary research with external capabilities • • • • • Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities • • • • • Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU) What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • • • • • • • Support your multidisciplinary research with external capabilities • • • • • Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities • • • • • Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU) What Your CTSA Can Do for You! 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