The NIEHS Training and Career Development Programs Spanning undergraduate summer research to faculty development; future directions. National Institute of Environmental Health Sciences Training and Career Development Opportunities Short-term Training Undergraduate Students (R25) Diversity Pre-doctoral (F31) Individual MD/PhD (F30) Short-term Training: Medical Students (T35) Institutional Training Grants Pre-, Post-doctoral (T32) Individual Post-doctoral (F32) Clinical Investigator Career Awards (K08, K23) National Institute of Environmental Health Sciences Career Transition Awards (K99/R00) Independent Research Career Faculty Development (K02, K24, F33, K25) “Training” = Ruth L. Kirschstein National Research Service Award (NRSA) Fellowships (F- series) T32 Institutional Training Grants (T32 mechanism) Short-Term Research Training for Health-Professional Students (T35 mechanism) National Institute of Environmental Health Sciences National Research Service Awards • Authority and Regulations: Section 487 of Public Health Service Act as amended (42 USC 288) and Federal Regulations 42 CFR 66 • June 3, 1983 plus amendments National Institute of Environmental Health Sciences Legislative Framework: Training Grants and Fellowships • U. S. Citizen or Permanent Resident • Research or training to undertake research: predoctoral leading to PhD, postdoctoral research • Training on full time basis • Max time of support: 5 years predoctoral, 3 years postdoctoral • Public or Nonprofit Private Institution (T32) National Institute of Environmental Health Sciences NRSA Budget Formula • Stipend ($21,600 predoctoral, $38,496$53,112 postdoctoral) • Tuition and fees (60% up to $16,000) • Travel • Training related expenses including Health Insurance ($4,200 per predoctoral, $7850 per postdoctoral) • No direct research funding National Institute of Environmental Health Sciences NIEHS NRSA Programs Individual Fellowships 55 total fellowships 27 - F30 Individual Predoctoral MD/PhD Fellowships 13 - F31 Individual Diversity Predoctoral Fellowships 15 - F32 Individual Postdoctoral Fellowships 0 – F33 Individual Senior Fellowships $2.1 M total cost Average: $38,400 total National Institute of Environmental Health Sciences NIEHS NRSA Programs T35 Short-Term Research Training for HealthProfessional Students Research training grants for short-term predoctoral positions reserved specifically to provide full-time, health-related research training experiences during the summer or other "off-quarter" periods. 4 T35s 28 med students total $1.0 M total cost National Institute of Environmental Health Sciences NRSA Programs T32 Institutional Training Grants 48 T32 Programs 271 predoctoral trainees 147 postdoctoral trainees $16.4 M total cost Average program 6 predocs 3 postdocs $350,000 total cost Program size span: 2 predocs + 1 postdoc to 20 predocs + 8 postdocs National Institute of Environmental Health Sciences Kirschstein-NRSA training grants and fellowships Funding in current and constant dollars – NIH total National Institute of Environmental Health Sciences Kirschstein-NRSA training grants and fellowships Pre- and Post-Doctoral full-time training positions awarded National Institute of Environmental Health Sciences PRE AND POST-DOCTORAL POSITIONS AS A PERCENT OF ALL KIRSCHSTEIN-NRSA POSITIONS Pre-Doctoral Post-Doctoral 60% Percent of all Positions 50% 40% 30% 20% 10% 0% 1998 1999 2000 2001 2002 2003 Fiscal Year Number of individuals appointed to institutional training positions are estimates Institute of Environmental Health Sciences TFNational 12 2004 2005 2006 2007 PRE AND POST-DOCTORAL KIRSCHSTEIN-NRSA RESEARCH TRAINING POSITIONS BY PARTICIPATING INSTITUTES AND CENTERS FY 2007 Pre-Doctoral Post-Doctoral 4,000 3,500 3,000 Number of Positions 2,500 2,000 1,500 1,000 500 Number of individuals appointed to institutional training positions are estimates National Institute of Environmental Health Sciences NI DC R NI DC D NH G RI NC RR NI NR NI AA A NI AM NC S CA M NE I K NI DA NI ND S NI BI B NI DD NI A ID NI M H NI CH D NH LB I NC NI I EH S NI A NI G M S 0 Participating NIH Institutes and Centers TF 13 NIEHS Mission Statement • The mission of the NIEHS is to reduce the burden of human illness and disability, by understanding how the environment influences the development and progression of human disease. National Institute of Environmental Health Sciences Recent Directions in Training (2006 Announcement) • Multidisciplinary and Interdisciplinary • Focus on environmental exposures in human health, human biology and human disease processes • Emphasis on gene x environment interactions and genomics • Defined focus on NIEHS mission area National Institute of Environmental Health Sciences Trainee Research Projects • NIEHS relevant exposures: industrial chemicals or byproducts, metals, pesticides, air pollutants, other inhaled toxicants like particulates or fibers, ambient exposures • Belongs to other NIH Institutes: alcohol, drugs of abuse, pharmaceuticals, infectious or parasitic agents, ionizing radiation, chemotherapeutics, etc. National Institute of Environmental Health Sciences Training Areas • Toxicologically related biomedical sciences and Environmental Medicine: 29 programs; 165 pre + 95 post slots • Environmental Epidemiology, Biostatistics and Bioinformatics: 12 programs; 72 pre + 32 post slots • Environmental Pathology: 4 programs; 18 pre + 13 post slots • Human Genes and the Environment: 3 programs; 16 pre + 9 post slots National Institute of Environmental Health Sciences Models for Training in Toxicological Sciences • Interdisciplinary Graduate Program • PhD in Toxicology offered by curriculum or Institute independent of Departmental affiliation, often answering to University Administration • Faculty, coursework drawn from multiple Departments, specific core curriculum National Institute of Environmental Health Sciences Models for Training in Toxicological Sciences • Multidisciplinary Graduate Program • Faculty participants from multiple Departments, coordinating administrative structure for training program • Students receive degrees through Departments • Common seminar series, journal clubs, core course(s) in toxicology National Institute of Environmental Health Sciences Moving Environmental Health Forward: Insights and Opportunities • NIEHS Stakeholder Community Workshop in July • Stakeholder workshop report: 12 strategic goals identified, then prioritized by vote • Strategic Plan web site: http://www.niehs.nih.gov/about/od/strate gicplan/index.cfm National Institute of Environmental Health Sciences Top 6 Topics and Scores • • • • • • Understanding how early life environmental exposures impact development and health across life span (83) Lead the advancement for state-of-the art for characterizing exposure to promote health and prevent disease (71) Attract, train, and retain the next generation of environmental health scientists and professionals (65) Connecting environmental influences to disease through the study of epigenomics and epigenetic mechanism as an opportunity and important long-term goal for NIEHS (62) Identify NIEHS as the Prevention Institute within NIH, through research, training, and education that leads to exposure reduction and disease prevention (60) Provide leadership and resources in translating and communicating scientific knowledge on the role of the environment on human health (60) National Institute of Environmental Health Sciences Training and Career Development Opportunities Short-term Training Undergraduate Students (R25) Diversity Pre-doctoral (F31) Individual MD/PhD (F30) Short-term Training: Medical Students (T35) Institutional Training Grants Pre-, Post-doctoral (T32) Individual Post-doctoral (F32) Clinical Investigator Career Awards (K08, K23) National Institute of Environmental Health Sciences Career Transition Awards (K99/R00) Independent Research Career Faculty Development (K02, K24, F33, K25) Training and Career Development Opportunities • Undergraduates – Summer research • Graduate students – training grants, targeted individual fellowships • Postdoctorals – training grants, individual fellowships • Career Transition – Career Development Awards (K series) • Faculty Development National Institute of Environmental Health Sciences