Larissa M. Podust Drug Discovery for Neglected Tropical Diseases • Moved to the Skaggs School of Pharmacy from UCSF in December 2014 • Center for Discovery and Innovation in Parasitic Diseases (CDIPD) directed by James McKerrow • CDIPD Structural Biology and X-ray Crystallography Core Core Expertise • • • • • Protein Chemistry Enzymology Structural Biology X-ray Crystallography Structure-based Drug Discovery Proposed Collaborations with SSPPS Faculty • Continue as CDIPD Structural Biology/X-ray Crystallography Core (collaboration with the Research Faculties and Project Scientists: Jair Lage (Kinetoplastids) and Anjan Debnath (Amoebas) • Collaboration with Tracy Handel on setting and maintaining Crystal Lab equipped with the shared state of the art instruments – Mosquito (LCP), Dragonfly and the UV Imager – for the service-based and collaborative research • Implement computation into structure-based drug-discovery project on Chagas Disease in collaboration with Ruben Abagyan • Three-way collaboration on phosphodiesterase 4 (PDE4)-related project is discussed with Susan Taylor and the new coming Faculty, Conor Caffey