Adult and Paediatric
Blackpool Teaching Hospitals
Supported by DRN and MCRN
Identifies new ways to prevent, identify and treat diabetes.
Identifies new ways to prevent, identify and treat diabetes

 Dr Ahmed, Principal Investigator
 Vas Vasudevan, Diabetes Research Nurse
 Established in Dec 2011. Based in Clinical Research
Centre, BTH.
 Working towards DOH – NIHR plan to improve health and wealth of the nation through research.
Identifies new ways to prevent, identify and treat diabetes

 So far
 1 in 3 patients attended diabetes clinic were informed about diabetes research activities in BTH.
 (DoH White paper 2010)
 Recruited to target
 Improving patient involvement
 Helped to promote and conduct research as core role in the BTH
 Helped to raise research awareness amongst staff, patient and public.
Identifies new ways to prevent, identify and treat diabetes

 DARE – Adult
 ADDRESS 1 - Paediatric
 ADDRESS-2 – Adult and Paediatric
 TRIALNET - Relatives of T1DM patients Adult and paediatric
 EPIC - Paediatric
Identifies new ways to prevent, identify and treat diabetes

 Aim – to produce a research database of all patients with diabetes.
 To produce a DNA repository of all diabetes patients
 Target – 500 patients per year
 Single visit, optional blood sample, questionnaire
 Recruitment started in dec2011, recruited 250 so far
 Data stored for
 Samples stored for indefinite period
Identifies new ways to prevent, identify and treat diabetes

 To recruit first degree relatives of T1DM patients, between 5 and 45 years.
 Aim – to determine the risk for the occurance of
T1DM using different tests.
 Looking to commence recruiting post July 2012 -
2015
 Blood samples and data collected, if antibodies are present, participants will be invited for further investigations.
Identifies new ways to prevent, identify and treat diabetes

 A fter D iabetes D iagnosis RE search S upport S ystem-2
 To recruit newly diagnosed T1DM patients and their non-diagnosed siblings.
 Data Collection and optional blood sample
 Follow up data is recorded 3mth and 6mth post consent only but stored up to 10 years
 To support future research into the development of
Type 1 diabetes and its prevention
 Recruited 4 adults, and 12 newly diagnosed children await being approached for research
Identifies new ways to prevent, identify and treat diabetes

 Dr Rabin Mohanty, Principal Investigator
 Angela Waktare Paediatric Diabetes Research Nurse
 and
 Sandra Singleton Paediatric Diabetes Research Nurse
 Established in Jan 2010, based in Clinical Research
Centre, BVH.
Identifies new ways to prevent, identify and treat diabetes

Study Overview Study Completion
To develop and evaluate an age appropriate education pack to support decision making and self care relating to insulin management and blood glucose monitoring.
The information packets are for:
6-10 years
11-15 years
16-18 years


Closed March 2012
Exceeded target recruited to the study (26)


3mth questionnaires and
6mth questionnaires completed
 First study undertaken by the
Team
 Positive feedback within a shorter recruitment time
Identifies new ways to prevent, identify and treat diabetes

 A fter D iagnosis RE search S upport S ystem
 A database of clinical measures post diagnosis of Type
1 Diabetes only
 Data is recorded 6mth post diagnosis then yearly till 5 years post diagnosis.
 Currently 11 children recruited
 All data is recorded from clinical records post initial consent
Identifies new ways to prevent, identify and treat diabetes

 16 newly diagnosed children await being approached for research
 Families are open to new developments which can improve care to their child
 Research creates a positive talking point where their child is the centre
 Families feel empowered as their contribution is essential to the success in recruiting to the trial and their information is invaluable to participating in the study
Identifies new ways to prevent, identify and treat diabetes

Identifies new ways to prevent, identify and treat diabetes