Fluorescent core-shell
silica nanoparticles
Jianming Kang
2013.3.30
1
Contents
2
Preparation
3
Applications
4
Conclusions
Introduction
Novel nanoscale fluorescent materials are integral to the
progress of emergent fields such as nanobiotechnology and
facilitate new research in a variety of contexts. Sol–gel
derived silica is an excellent host material for creating
fluorescent nanoparticles by the inclusion of covalentlybound organic dyes. Significant enhancements in the
brightness and stability of organic dye emission can be
achieved for silica-based core–shell nanoparticle
architectures at length scales down to tens of nanometers
with narrow size distributions.
Several nanoscale fluorescent
materials
Reaction types
1.Substitution reaction
Ammonolysis reaction
other substitution reaction
2. Addition reaction
C=C bond
C=N bond
3. Condensation reaction
Ammonolysis reaction
Other substitution reaction
C=C bond addition reaction
C=N bond addition reaction
Condensation reaction
Applications in biology and medicine
pH sensing
Cell imaging
Throughout my presentation, many kinds of reaction types
have been introduced that demonstrate the versatility of
fluorescent silica nanoparticles. Also, we can add different
shells to create probes tailored to explore specific biological
questions at near-molecular scale. The versatility provides
a wide and open space for innovative research for
nanobiotechnology and beyond.
Thank you!
感谢各位老师和同学
欢迎大家提出宝贵意见