Introduction to the Chemical Biology Program Chulabhorn Graduate Institute June 5th, 2012 Chemical Biology • Emphasizes the interface between Chemistry and Biology, as well as its potential applications for other fields • Involves the study of interactions between small molecules and their possible biological targets, the study of biological pathways using chemical tools, drug delivery, as well as chemical understanding of disease states, in order to create basic science knowledge for future drug discovery efforts 2 Curriculum • M.Sc. Program – Coursework – Thesis Research – Duration 24 credits 12 credits 2-2.5 academic years • Ph.D. Program M.Sc. – Coursework – Thesis Research – Duration 24 credits 36 credits 3.5 acad. yrs. B.Sc. 24 credits 48 credits 4-5 acad. yrs. 3 Courses • Students may choose one of the two tracks in either Chemistry or Biology, depending on the strength of their previous training and experience. • Students must take 5 required courses and 3-4 electives. • Required courses include: – Principles of Applied Biosciences: Systems Biology – Experimental Strategies for Biological Problems – Drug Discovery and Development – Spectroscopic Methods for Organic Compounds and Biomolecules – Case Studies in Applied Biosciences (Biology-track students) – Advanced Organic Chemistry (Chemistry-track students) • Electives may be selected from a number of chemistry-oriented courses offered in this program and the courses from the ET or ABS programs. 4 Research Areas • Organic Synthesis/Medicinal Chemistry – Development of synthetic methodologies – Total synthesis of complex natural products • Natural Products Chemistry – Extraction, isolation, purification, and structure elucidation of natural products from plants, marine organisms, and microorganisms • Chemistry and Biology of Biomolecules – Application of integrated and multidisciplinary approaches to solve problems involving biomolecules, especially proteins and carbohydrates 5 Faculty Members Prof. Somsak Ruchirawat Chair Dr. Prasat Kittakoop (Nat. Prod.) Dr. Nopporn Thasana (Org. Syn. & Nat. Prod.) Dr. Poonsakdi Ploypradith (Org. Syn. & Med. Chem.) Dr. Montakarn Chittchang (Pharm. Sci. & Med. Chem.) Dr. Charnsak Thongsornkleeb (Org. Syn.) 6 Faculty Members (CRI) Prof. Supanna Dr. Anucha Dr. Arthit Dr. Hunsa Dr. Jumreang Dr. Jutatip Dr. Nisachon Dr. Phanruethai Dr. Poolsak Dr. Sirirat Dr. Vilailak Dr. Wannaporn Dr. Watcharra Dr. Winai 7 Faculty Members (external) CGAB courses: Prof. Essigmann MIT, USA Prof. Sasisekharan MIT, USA Prof. Engelward MIT, USA Prof. Dedon MIT, USA Prof. Isobe NTHU, Taiwan Aj. Polkrit CU Aj. Kiattawee KU Dr. Gleeson KU Aj. Boon-ek RU Aj. Siwarutt SITT, TU Dr. Suchart Thai FDA Mr. Sprenger 8 Bruker CGCB courses: CB Students & Alumni • Class of 2007 (8) – M.Sc./Ph.D. Program 1. Ms. Acharavadee Pansanit 2. Ms. Sasiwadee Boonya-udtayan Dr. Prasat Dr. Nopporn – M.Sc. Program 3. 4. 5. 6. 7. 8. Ms. Nattha Ingavat Ms. Pacharin Kamolkijkarn Mr. Paratchata Batsomboon Ms. Sukanya Eursakun Ms. Thitawan Prasertdee Mr. Kyaw Thet Oo Dr. Prasat Dr. Songpon Dr. Poonsakdi Prof. Dr. Kavi (ABS) Dr. Songpon Dr. Prasat 9 CB Students & Alumni (cont’d) • Class of 2008 (8) – M.Sc./Ph.D. Program 1. Mr. Prattya Nealmongkol Dr. Nopporn – M.Sc. Program 2. 3. 4. 5. 6. 7. 8. Mr. Anon Bunrit Ms. Jarinee Maneekul Ms. Kamolchanok Tianpanich Mr. Pakornwit Sarnpitak Mr. Suttipol Radomkit Ms. Seaim Lwin Aye Mr. Thinley Gyeltshen Dr. Charnsak Dr. Apinya (ABS) Dr. Prasat Dr. Poonsakdi Dr. Poonsakdi Dr. Suvit (ABS) Dr. Prasat 10 CB Students & Alumni (cont’d) • Class of 2009 (7) – M.Sc./Ph.D. Program 1. Mr. Chakree Wattanasiri Dr. Siwarutt (SIIT) – M.Sc. Program 2. 3. 4. 5. 6. 7. Ms. Parichart Kedkum Ms. Patchaya Sukjarean Mr. Prateep Worawittayanon Mr. Tawan Chaiwon Ms. Varisa Katesompao Mr. Santi Prasad Bajgai Dr. Bodin (CU) Dr. Poonsakdi Dr. Nopporn Dr. Anucha Dr. Poonsakdi Dr. Prasat 11 CB Students & Alumni (cont’d) • Class of 2010 (8) – M.Sc. Program 1. 2. 3. 4. 5. 6. 7. 8. Mr. Chatchai Kesornpun Dr. Prasat Ms. Chiobouaphong Phakeovilay Dr. Tripetch (KKU) Ms. Kamil Prajapati Dr. Montakarn Mr. Le Van Huy Dr. Kriangsak Mr. Panatpong Hutacharoen Dr. Siwarutt (SIIT) Ms. Sarath Parakumge Dayani Senadeera Dr. Prasat Ms. Sofia Bensulong Dr. Jutatip Mr. Wangchuk Rabten Dr. Charnsak 12 CB Students & Alumni (cont’d) • Class of 2011 (6) – M.Sc. Program 1. 2. 3. 4. 5. 6. Mr. Haris Leelayuwapan Ms. Kanokrat Trongchit Ms. Rapeepat Sangsuwan Ms. Vorathip Sawattanai Mr. Wuttikiat Jullamanop Mr. Tsherwang Dendup Dr. Siwarutt (SIIT) Dr. Poonsakdi Dr. Prasat Dr. Siwarutt (SIIT) Dr. Prasat Dr. Prasat 13 CB Students & Alumni (cont’d) • Class of 2012 (11) – M.Sc. Program 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. Ms. Apiwan Jumruksa Ms. Apsorn Watthanaudomchai Mr. Harin Leelayuwapan Mr. Kasidej Poonsilp Mr. Kittikun Songsomboon Mr. Nattapong Asawatinnapan Mr. Pasuk Aroonkit Ms. Tapanee Maibunkaew Ms. Dakshina Udayamali Ganihigama Mr. Mario Wibowo Mr. T. H. N. R. T. Hewage Prof. Dr. Somsak Dr. Prasat Dr. Nopporn Dr. Poonsakdi Prof. Dr. Somsak Dr. Montakarn Dr. Charnsak Dr. Charnsak Dr. Poonsakdi Dr. Prasat Dr. Nopporn 14 Desirable Traits of CGI Students • • • • • • • Punctuality Honesty and Integrity Pride Humility Assertiveness Diligence Curiosity 15 CGI: the Enabling Institution At CGI, we will instill in you with the ability to • Creatively perform original and novel research work • Efficiently perform multitask • Effectively communicate with your peers as well as others • Think critically • Be knowledgeable, resourceful, and instrumental • Ultimately become the future leaders in science and technology 16